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1 Adenosine 3':5'-cyclic monophosphate induces regulated secretion of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells
article 1998    
Author: Hegeman, R.J. · Eijnden-Schrauwen, Y. van den · Emeis, J.J.
Keywords: 8-Bromo Cyclic Adenosine Monophosphate · Adenosine · Bucladesine · Calcium · Cells, Cultured · Cholera Toxin · Cyclic AMP · Endothelium, Vascular · Epoprostenol · Forskolin · Humans · Isoproterenol · Second Messenger Systems · Secretory Rate · Thrombin · Tissue Plasminogen Activator · von Willebrand Factor
[Abstract]

2 Effect of the acquisition enhancing drug piracetam on rat cerebral energy metabolism. Comparison with naftidrofuryl and methamphetamine
article 1976    
Author: Nickolson, V.J. · Wolthuis, O.L.
Keywords: Biology · Adenine nucleotide · Adenylate kinase · Methamphetamine · Naftidrofuryl · Piracetam · Brain · Energy transfer · Histochemistry · In vitro study · Rat · Theoretical study · Adenosine Diphosphate · Adenosine Monophosphate · Adenosine Triphosphate · Adenylate Kinase · Animal · Cerebral Cortex · Comparative Study · Energy Metabolism · Furans · In Vitro · Male · Methamphetamine · Nafronyl · Piracetam · Pyrrolidinones · Rats
[Abstract]

3 Low efficacy adenosine A1 agonists inhibit striatal acetylcholine release in rats improving central selectivity of action
article 2003    
Author: Bueters, T.J.H. · Helden, H.P.M. van · IJzerman, A.P. · Danhof, M.
Keywords: Acetylcholine · Adenosine · Adenosine A1 receptor · Low efficacy agonist · Microdialysis · Tissue selectivity · 2' deoxy 6 n cyclopentyladenosine · 3' deoxy 6 n cyclopentyladenosine · 6 n cyclopentyladenosine · 8 butylamino 6 n cyclopentyladenosine · 8 cyclopentyltheophylline · 8 ethylamino 6 n cyclopentyladenosine · Acetylcholine · Adenosine A1 receptor agonist · Unclassified drug · Acetylcholine release · Animal experiment · Animal tissue · Cardiovascular system · Controlled study · Corpus striatum · Dose response · Drug effect · Drug efficacy · Male · Microdialysis · Nonhuman · Rat · Animals · Dose-Response Relationship, Drug · Microdialysis · Neostriatum · Rats, Wistar · Receptor, Adenosine A2B · Receptors, Purinergic P1 · Reproducibility of Results · Sensitivity and Specificity · 6 n cyclopentyladenosine, 41552-82-3 · 8 cyclopentyltheophylline, 35873-49-5 · Acetylcholine, 51-84-3, 60-31-1, 66-23-9 · Adenosine, 58-61-7; · N(6)-cyclopentyladenosine, 41552-82-3 · Receptor, Adenosine A2B · Receptors, Purinergic P1
[Abstract]

4 Long-term niacin treatment induces insulin resistance and adrenergic responsiveness in adipocytes by adaptive downregulation of phosphodiesterase 3B
article 2014    
Author: Heemskerk, M.M. · Berg, S.A. van den · Pronk, A.C.M. · Klinken, J.B. van · Boon, M.R. · Havekes, L.M. · Rensen, P.C.N. · Willems van Dijk, K. · Harmelen, V. van
Keywords: Biology · Adenosine 3'-,5'-cyclic monophosphate · Adipose tissue · Lipolysis · Phosphodiesterases · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

5 New generic approach to the treatment of organophosphate poisoning: Adenosine receptor mediated inhibition of ACh-release
article 1998    
Author: Helden, H.P.M. van · Groen, B. · Moor, E. · Westerink, B.H.C. · Bruijnzeel, P.L.B.
Keywords: Adenosine-5'-(N-ethylcarboxamide) · Animals · Brain Chemistry · Cholinesterase Inhibitors · Dinucleoside Phosphates · Injections, Intramuscular · Injections, Subcutaneous · Poisoning · Rats · Receptors, Purinergic P1 · Soman · Survival Rate · Time Factors
[Abstract]

6 Assessment of some critical factors in the freezing technique for the cryopreservation of precision-cut rat liver slices
article 2000    
Author: Maas, W.J.M. · Graaf, I.A.M. de · Schoen, E.D. · Koster, H.J. · Sandt, J.J.M. van de · Groten, J.P.
Keywords: Production · Technology · Food · Adenosine triphosphate · Cryoprotective agent · Glutathione · Lactate dehydrogenase · Potassium · Testosterone · Animal tissue · Cell death · Cell metabolism · Cell viability · Controlled study · Cryopreservation · Enzyme activity · Freezing · Liver preservation · Male · Nonhuman · Priority journal · Protein content · Rat · Technique · Adenosine Triphosphate · Animals · Cryopreservation · Dinitrochlorobenzene · Evaluation Studies · Glutathione · Glutathione Transferase · L-Lactate Dehydrogenase · Liver · Male · Microtomy · Potassium · Proteins · Rats · Rats, Wistar · Testosterone · Tissue Preservation · Urea · Animalia
[Abstract]

7 Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi α-subunits
article 2004    
Author: Klaasse, E. · Ligt, R.A.F.de · Roerink, S.F. · Lorenzen, A. · Milligan, G. · Leurs, R. · IJzerman, A.P.
Keywords: Health · Physiological Sciences · Adenosine A1 receptor · Allosteric modulation · Constitutive activity · Fusion protein · G protein · Inverse agonism · 2 amino 4,5 dimethyl 3 (3 trifluoromethylbenzoyl)thiophene · 6 n cyclopentyladenosine · 8 cyclopentyl 1,3 dipropylxanthine · 8 cyclopentyltheophylline · Adenosine A1 receptor · Amino acid · Arginine · Cysteine · Glycine · Guanine nucleotide binding protein · Guanosine 5' o (3 thiotriphosphate) · Histidine · Hybrid protein · Isoleucine · Phenylalanine · Proline · Radioligand · Serine · Sodium ion · Sulfur 35 · Valine · Allosterism · Alpha chain · Animal cell · Cercopithecidae · Ligand binding · Nonhuman · Priority journal · Protein analysis · Adenosine · Allosteric Site · Animals · Binding, Competitive · Cell Membrane · COS Cells · Cysteine · Dose-Response Relationship, Drug · GTP-Binding Protein alpha Subunits, Gi-Go · Guanosine 5'-O-(3-Thiotriphosphate) · Humans · Mutation · Radioligand Assay · Receptor, Adenosine A1 · Recombinant Fusion Proteins · Sodium Chloride · Sulfur Radioisotopes · Thiophenes · Transfection · Tritium · Xanthines
[Abstract]

8 On the role of bradykinin in secretion from vascular endothelial cells
article 1992    
Author: Emeis, J.J. · Tranquille, N.
Keywords: 8-Bromo Cyclic Adenosine Monophosphate · Animal · Atrial Natriuretic Factor · Bradykinin · Calcium · Calcium Channel Blockers · Cyclic AMP · Cyclic GMP · Endothelium, Vascular · Forskolin · Hindlimb · Kinetics · Male · Nitroprusside · Perfusion · Rats · Rats, Wistar · Receptors, Bradykinin · Receptors, Neurotransmitter · Tissue Plasminogen Activator · von Willebrand Factor
[Abstract]

9 Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP
article 1996    
Author: Zaman, G.J.R. · Cnubben, N.H.P. · Bladeren, P.J. van · Evers, R. · Borst, P.
Keywords: Adenosine Monophosphate · ATP-Binding Cassette Transporters · Biological Transport · Carcinoma, Non-Small-Cell Lung · Cell Membrane · Drug Resistance, Multiple · Ethacrynic Acid · Glutathione · Humans · Kinetics · Lung Neoplasms · Multidrug Resistance-Associated Proteins · Recombinant Proteins · Saccharomyces cerevisiae · Sulfinpyrazone · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

10 Accurate determination of process variables in a solid-state fermentation system
article 1996    
Author: Smits, J.P. · Rinzema, A. · Tramper, J. · Schlösser, E.E. · Knol, W.
Keywords: Nutrition · adenosine triphosphate · carboxymethylcellulose · hydrolase · analytic method · article · carbon dioxide transport · chemical composition · diagnostic accuracy · fermentation · oxygen consumption · solid state · trichoderma reesei · wheat bran · Hypocrea jecorina · Trichoderma · Triticum aestivum
[Abstract]

11 Transport of glutathione A conjugates by the multifrug resistance protein 1
article 1997    
Author: Evers, R. · Cnubben, N.H.P. · Wijnholds, J. · Deemter, L. van · Bladeren, P.J. van · Borst, P.
Keywords: GS-X pump · Multidrug resistance · Adenosine Triphosphate · Animals · Biological Transport · Cell Line · Cell Polarity · Cyclic AMP · Dogs · Erythrocytes · Ethacrynic Acid · Glutathione · Humans · Kidney · Methotrexate · Mice · Mice, Mutant Strains · Microsomes · P-Glycoprotein · Prostaglandins A, Synthetic · Stereoisomerism
[PDF] [Abstract]

12 Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle
article 1996    
Author: Vliet, A.K. van · Nègre-Arrariou, P. · Thiel, G.C.F. van · Bolhuis, P.A. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitors · Human myoblasts · Sterol synthesis · Adenosine triphosphate · Hydroxymethylglutaryl coenzyme a reductase inhibitor · Mevinolin · Mitochondrial enzyme · Cell culture · Cell proliferation · Cell viability · Concentration response · Controlled study · Dna synthesis · Human cell · Human tissue · Muscle biopsy · Myoblast · Myopathy · Skeletal muscle · Acetic Acid · Adenosine Triphosphate · Anticholesteremic Agents · Cell Division · Cell Survival · Cells, Cultured · DNA · Enzyme Inhibitors · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Mitochondria · Muscle, Skeletal · Oxidoreductases · Pravastatin · Simvastatin · Sterols
[Abstract]

13 Factors affecting the transduction of pluripotent hematopoietic stem cells: Long-term expression of a human adenosine deaminase gene in mice
article 1993    
Author: Einerhand, M.P.W. · Bakx, T.A. · Kukler, A. · Valerio, D.
Keywords: Adenosine deaminase · Interleukin 1alpha · Interleukin 3 · Animal cell · Bone marrow cell · Cell transplantation · Colony forming unit s · Controlled study · Gene expression · Gene transfer · Genetic transduction · Hematopoietic stem cell · Human · Mouse · Nonhuman · Retrovirus · Adenosine Deaminase · Animal · Bone Marrow · Bone Marrow Cells · Bone Marrow Transplantation · Cells, Cultured · Fluorouracil · Gene Expression · Genetic Vectors · Hematopoietic Cell Growth Factors · Hematopoietic Stem Cells · Interleukin-1 · Interleukin-3 · Mice · Mice, Inbred C57BL · Mice, Inbred CBA · Retroviridae · Spleen · Stem Cell Factor · Transfection
[Abstract]

14 Cyclopentyladenosine and some of its low-efficacy derivatives inhibit striatal synaptosomal release of acetylcholine to a similar degree
article 2003    
Author: Bueters, T.J.H. · Duivenvoorde, L.M. van · Danhof, M. · IJzerman, A.P. · Helden, H.P.M. van
Keywords: Biology · 3D-CPA (3′-deoxy-CPA) · 8-BCPA (8-butylamino-CPA) · 8-PCPA (8-propylamino-CPA) · Acetylcholine release · Adenosine A1 receptor · CPA (cyclopentyladenosine) · Low-efficacy agonist · Neuronal synaptosome · Partial agonist · 3' deoxy 6 n cyclopentyladenosine · 8 butylamino 6 n cyclopentyladenosine · 8 propylamino 6 n cyclopentyladenosine · Adenosine A2 receptor antagonist · Adenosine derivative · Adenosine receptor blocking agent · Partial agonist · Tritium · Unclassified drug · Animal tissue · Brain synaptosome · Cardiotoxicity · Concentration response · Controlled study · Corpus striatum · Drug effect · Evoked response · Inhibition kinetics · Male · Nonhuman · Rat · Adenosine · Animals · Dose-Response Relationship, Drug · Rats, Wistar · Synaptosomes · 4 aminopyridine, 1003-40-3, 504-24-5 · 5 amino 2 (2 furyl) 7 (2 phenylethyl)pyrazolo[4,3 e][1,2,4]triazolo[1,5 c]pyrimidine, 160098-96-4 · 6 n cyclopentyladenosine, 41552-82-3 · Acetylcholine, 51-84-3, 60-31-1, 66-23-9 · Theophylline, 58-55-9, 5967-84-0, 8055-07-0, 8061-56-1, 99007-19-9 · Tritium, 10028-17-8 · Adenosine, 58-61-7 · N(6)-cyclopentyladenosine, 41552-82-3
[Abstract]

15 Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication
article 2002    
Author: Bueters, T.J.H. · Groen, B. · Danhof, M. · IJzerman, A.P. · Helden, H.P.M. van
Keywords: Biology · Acetylcholine release · Adenosine A1 receptor · N6-Cyclopentyladenosine · Organophosphate · Adenosine A1 receptor agonist · Adenosine receptor stimulating agent · Cyclohexyladenosine · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Adenosine receptor · Cholinesterase · Drug derivative · N(6) cyclopentyladenosine · Organophosphate · Phosphorothioic acid derivative · Bioaccumulation · Cholinergic system · Concentration response · Controlled study · Corpus striatum · Crug efficacy · Enzyme activity · Hippocampus · Intoxication · Male · Microdialysis · Nonhuman · Rat · Reduction · Animal · Drug potentiation · Enzymology · Metabolism · Secretion · Wistar rat · Animals · Cholinesterase Inhibitors · Cholinesterases · Corpus Striatum · Male · Microdialysis · Organothiophosphorus Compounds · Parathion · Phosphoric Acid Esters · Rats · Rats, Wistar · Receptors, Purinergic P1 · Sarin · Acetylcholinesterase, 9000-81-1 · Cyclohexyladenosine, 36396-99-3 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Parathion, 3270-86-8, 56-38-2, 597-88-6 · Sarin, 107-44-8; tabun, 77-81-6 · Acetylcholine, 51-84-3 · Adenosine, 58-61-7; · Cholinesterase Inhibitors · Cholinesterases, EC 3.1.1.8 · N(6)-cyclopentyladenosine, 41552-82-3 · Organothiophosphorus Compounds · Parathion, 56-38- · Phosphoric Acid Esters · Receptors, Purinergic P1 · Sarin, 107-44-8 · Tabun, 77-81-6 · VX, 50782-69-9
[Abstract]

16 Secondary structure of the intact H+,K+ -ATPase and of its membrane-embedded region. An attenuated total reflection infrared spectroscopy, circular dichroism and Raman spectroscopy study
article 1998    
Author: Raussens, V. · Jongh, H. de · Pézolet, M. · Ruysschaert, J.-M. · Goormaghtigh, E.
Keywords: Perception · Attenuated total reflection · Fourier-transform infrared spectroscopy · Gastric · H<sup>+</sup>,K<sup>+</sup>-exchanging ATPase · adenosine triphosphatase · amino acid · hydrogen potassium adenosine triphosphatase · membrane enzyme · proteinase · proteinase k · animal experiment · animal tissue · article · circular dichroism · controlled study · enzyme localization · infrared spectroscopy · neurospora crassa · nonhuman · priority journal · protein degradation · protein secondary structure · raman spectrometry · stomach tube · Animals · Circular Dichroism · Endopeptidase K · Gastric Mucosa · H(+)-K(+)-Exchanging ATPase · Membrane Proteins · Peptide Fragments · Protein Structure, Secondary · Spectroscopy, Fourier Transform Infrared · Spectrum Analysis, Raman · Swine · Animalia · Garcia · Neurospora crassa
[Abstract]

17 Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice
article 2011    
Author: Coomans, C.P. · Biermasz, N.R. · Geerling, J.J. · Guigas, B. · Rensen, P.C.N. · Havekes, L.M. · Romijn, J.A.
Keywords: Biology · adenosine triphosphate sensitive potassium channel · glucose · insulin · tolbutamide · adipose tissue · animal experiment · animal tissue · article · central nervous system · controlled study · diet · gluconeogenesis · glucose transport · heart · hyperinsulinemia · insulin resistance · insulin sensitivity · lateral brain ventricle · male · mouse · muscle · nonhuman · obesity · priority journal · signal transduction · stimulation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

18 Synthesis and biological evaluation of disubstituted N6- cyclopentyladenine analogues: The search for a neutral antagonist with high affinity for the adenosine A1 receptor
article 2004    
Author: Ligt, R.A.F. de · Klein, P.A.M. van der · Frijtag Drabbe Künzel, J.K. von · Lorenzen, A. · El Maate, F.A. · Fujikawa, S. · Westhoven, R. van · Hoven, T. van den · Brussee, J. · Ijzerman, A.P.
Keywords: Biology Toxicology · Physiological Sciences · [35S]GTPγS binding · Adenosine A1 receptor · Inverse agonism · N-0840 derivatives · Neutral antagonist · 8 bromo 9 methyladenine · 8 bromo n 6 cyclopentyl 9 methyladenine · 8 bromo n 6 cyclopentyl 9 propyladenine · 9 allyl 8 bromo n 6 cyclopentyladenine · 9 allyl n 6 cyclopentyl 8 methoxyadenine · adenine derivative · adenosine A1 receptor antagonist · luf 5666 · luf 5668 · luf 5669 · luf 5674 · n 0840 · n 6 cyclopentyl 8 (ethylthio) 9 methyladenine · n 6 cyclopentyl 8 (n ethyl n butylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methyl n ethylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methyl n propylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methylisopropylamino) 9 methyladenine · n 6 cyclopentyl 8 (n piperidino) 9 methyladenine · n 6 cyclopentyl 8 (n pyrrolidino) 9 methyladenine · n 6 cyclopentyl 8 (n,n diethylamino) 9 methyladenine · n 6 cyclopentyl 8 ethoxy 9 methyladenine · n 6 cyclopentyl 8 isopropoxy 9 methyladenine · n 6 cyclopentyl 8 methoxy 9 methyladenine · n 6 cyclopentyl 8 methoxy 9 propyladenine · n 6 cyclopentyl 9 methyl 8 oxoadenine · n 6 cyclopentyl 9 methyl 8 propoxyadenine · n 6 cyclopentyl 9 methyladenine · unclassified drug · article · binding affinity · drug determination · drug synthesis · drug tolerability · receptor affinity · substitution reaction · Adenine · Adenosine · Animals · Cell Line · CHO Cells · Cricetinae · Drug Evaluation, Preclinical · Humans · Receptor, Adenosine A1
[Abstract]

19 Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2
article 2008    
Author: Wortelboer, H.M. · Balvers, M.G.J. · Usta, M. · Bladeren, P.J. van · Cnubben, N.H.P.
Keywords: Health · Physiological Sciences · Arsenic trioxide · Cisplatin · Glutathione · Mercury chloride · MRP1 · MRP2 · Adenosine triphosphatase · Calcein · Cisplatin · Glutathione · Multidrug resistance protein 1 · Multidrug resistance protein 2 · Animal cell · Cell viability · Complex formation · Controlled study · Enzyme activity · Kidney cell · Membrane vesicle · Molecular interaction · Nonhuman · Protein expression · Transport kinetics
[Abstract]

20 Transport of D-xylose in Lactobacillus pentosus, Lactobacillus casei, and Lactobacillus plantarum: Evidence for a mechanism of facilitated diffusion via the phosphoenolpyruvate:mannose phosphotransferase system
article 1999    
Author: Chaillou, S. · Pouwels, P.H. · Postma, P.W.
Keywords: Nutrition · Mannose · Phosphoenolpyruvate sugar phosphotransferase · Xylose · Bacterial growth · Carbohydrate transport · Diffusion · Enzyme mechanism · Fermentation · Lactobacillus · Lactobacillus casei · Lactobacillus pentosus · Lactobacillus plantarum · Nonhuman · Priority journal · Adenosine Triphosphate · Biological Transport, Active · Carbon Radioisotopes · Diffusion · Genetic Complementation Test · Kinetics · Lactobacillus casei · Mannose · Mutation · Phosphoenolpyruvate · Phosphoenolpyruvate Sugar Phosphotransferase System · Plasmids · Species Specificity · Transformation, Genetic · Xylose
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 28 found. Next | Sort by date