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1 Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion
article 2001    
Author: Kypreos, K.E. · Dijk, K.W. van · Zee, A. van der · Havekes, L.M. · Zannis, V.I.
Keywords: Biology · Adenoviridae · Animalia · Adenoviridae · Animals · Apolipoprotein E4 · Apolipoproteins E · Base Sequence · Cholesterol · Chromatography, Liquid · DNA Primers · Female · Homeostasis · Humans · Liver · Mice · Mice, Knockout · RNA, Messenger · Triglycerides · Tumor Cells, Cultured
[PDF] [Abstract]

2 Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
article 2003    
Author: Laan, W.H. van der · Quax, P.H.A. · Seemayer, C.A. · Huisman, L.G.M. · Pieterman, E.J. · Grimbergen, J.M. · Verheijen, J.H. · Breedveld, F.C. · Gay, R.E. · Gay, S. · Huizinga, T.W.J. · Pap, T.
Keywords: Adenoviridae · Animals · Arthritis, Rheumatoid · Cartilage, Articular · Cell Division · Fibroblasts · Gene Expression · Gene Therapy · Genetic Vectors · Humans · Matrix Metalloproteinases · Mice · Mice, SCID · Synovial Membrane · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Transduction, Genetic · Adenoviridae · Animalia
[Abstract]

3 Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain
article 2003    
Author: Gerritsen, G. · Kypreos, K.E. · Zee, A. van der · Teusink, B. · Zannis, V.I. · Havekes, L.M. · Dijk, K.W. van
Keywords: Biology · Adenoviridae · Animals · Apolipoprotein E2 · Apolipoprotein E4 · Apolipoproteins E · Cholesterol · Humans · Hyperlipidemias · Lipids · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · Protein Structure, Tertiary · Triglycerides
[PDF] [Abstract]

4 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

5 In vivo suppression of restenosis in balloon-injured rat carotid artery by adenovirus-mediated gene transfer of the cell surface-directed plasmin inhibitor ATF.BPTI
article 2001    
Author: Lamfers, M.L.M. · Lardenoye, J.H.P. · Vries, M.R. de · Aalders, M.C. · Engelse, M.A. · Grimbergen, J.M. · Hinsbergh, V.W.M. van · Quax, P.H.A.
Keywords: Adenoviridae · Angioplasty, Balloon · Animals · Aprotinin · Carotid Arteries · Carotid Stenosis · Cell Culture Techniques · Gene Expression · Gene Therapy · Gene Transfer Techniques · Genetic Vectors · Humans · Male · Peptide Fragments · Plasmin · Rats · Rats, Sprague-Dawley · Recurrence · RNA, Messenger · Tunica Intima · Tunica Media · Urinary Plasminogen Activator · Adenoviridae · Animalia · Bovinae
[Abstract]

6 Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor
article 1998    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Zee, A. van der · Hof, B. van 't · Boom, H. van der · Kobayashi, K. · Chan, L. · Havekes, L.M. · Hofker, M.H.
Keywords: Health · ApoE variants · Atherosclerosis · Gene therapy · VLDL receptor · Adenoviridae · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Female · Gene Transfer Techniques · Humans · Hypercholesterolemia · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL · Triglycerides
[Abstract]

7 In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE
article 1999    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Hof, H.B. van 't · Zee, A. van der · Santamarina-Fojo, S. · Berkel, T.J.C. van · Havekes, L.M. · Hofker, M.H.
Keywords: Health · Adenovirus-mediated gene transfer · Hepatic VLDL triglyceride production · Hypertriglyceridemia · LDL receptor-related protein · VLDL-triglyceride lipolysis · Adenovirus · Adenoviridae · Animals · Apolipoproteins E · Cholesterol · Female · Humans · Immunohistochemistry · Lipolysis · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Receptors, LDL · Transfection · Triglycerides
[PDF] [Abstract]

8 Apolipoprotein E2 (Lys146→Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides
article 2000    
Author: Beer, F. de · Dijk, K.W. van · Jong, M.C. · Vark, L.C. van · Zee, A. van der · Hofker, M.H. · Fallaux, F.J. · Hoeben, R.C. · Smelt, A.H.M. · Havekes, L.M.
Keywords: Adenoviridae · Alleles · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Gene Expression · Gene Transfer Techniques · Humans · Hydrolysis · Hyperlipoproteinemia Type III · Hypertriglyceridemia · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · Point Mutation · RNA, Messenger · Triglycerides
[Abstract]

9 In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 → Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice
article 1996    
Author: Vlijmen, B.J.M. van · Dijk, K.W. van · Hof, H.B. van 't · Gorp, P.J.J. van · Zee, A. van der · Boom, H. van der · Breuer, M.L. · Hofker, M.H. · Havekesf, L.M.
Keywords: Animals · Apolipoproteins E · Arginine · Cells, Cultured · Cysteine · Genes, Dominant · Heymann Nephritis Antigenic Complex · Hyperlipoproteinemias · Lipoproteins, LDL · Lipoproteins, VLDL · Membrane Glycoproteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL · Adenoviridae · Animalia · Mus musculus
[PDF] [Abstract]

10 Adenovirus-mediated transfer of the 39 kD receptor-associated protein increases fibrinolytic capacity
article 2001    
Author: Goedde, M.F. · Grimbergen, J.M. · Toet, K.H. · Sitter, T. · Quax, P.H. · Kooistra, T.
Keywords: Adenoviridae · Carrier Proteins · Cells, Cultured · Culture Media, Conditioned · Down-Regulation · Drug Stability · Epithelial Cells · Fibrinolysis · Gene Transfer Techniques · Genetic Vectors · Glycoproteins · Humans · Immunoblotting · LDL-Receptor Related Protein-Associated Protein · Peritoneum · Peritonitis · Time Factors · Tissue Extracts · Tissue Plasminogen Activator
[Abstract]

11 Effect of neutralizing sera on factor X-mediated adenovirus serotype 5 gene transfer
article 2009    
Author: Parker, A.L. · Waddington, S.N. · Buckley, S.M.K. · Custers, J. · Havenga, M.J.E. · Rooijen, N. van · Goudsmit, J. · McVey, J.H. · Nicklin, S.A. · Baker, A.H.
Keywords: Biology · Biomedical Research · Adenovirus · article · correlation analysis · fiber · gene therapy · gene transfer · genetic transduction · immunity · in vitro study · liver cell · nonhuman · priority journal · pseudotyping · screening · serotype · gene vector · human · immunology · metabolism · methodology · serodiagnosis · tumor cell line · virology · virus attachment · Adenoviridae · antiserum · blood clotting factor 10 · Adenoviridae · Cell Line, Tumor · Factor X · Gene Therapy · Genetic Vectors · Hepatocytes · Humans · Immune Sera · Neutralization Tests · Transduction, Genetic · Virus Attachment
[Abstract]

12 Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
article 2009    
Author: Liu, J. · O'Brien, K.L. · Lynch, D.M. · Simmons, N.L. · Porte, A. La · Riggs, A.M. · Abbink, P. · Coffey, R.T. · Grandpre, L.E. · Seaman, M.S. · Landucci, G. · Forthal, D.N. · Montefiori, D.C. · Carville, A. · Mansfield, K.G. · Havenga, M.J. · Pau, M.G. · Goudsmit, J. · Barouch, D.H.
Keywords: Health · Biomedical Research · adenovirus vector · antigen · vaccine · allele · cytology · gene expression · human immunodeficiency virus · immune response · primate · recombination · vaccine · acquired immune deficiency syndrome · animal experiment · animal model · article · cellular immunity · controlled study · immune response · immunogenicity · mortality · nonhuman · priority journal · rhesus monkey · serology · Simian immunodeficiency virus · T lymphocyte · therapy effect · virus load · Adenoviridae · Animals · Antibodies, Viral · CD4-Positive T-Lymphocytes · HIV Infections · Humans · Macaca mulatta · Neutralization Tests · SAIDS Vaccines · Simian Acquired Immunodeficiency Syndrome · Simian immunodeficiency virus · Vaccination · Viral Load · Adenoviridae · Animalia · Human immunodeficiency virus 1 · Macaca mulatta · Simian immunodeficiency virus
[Abstract]

13 Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells
article 2000    
Author: Geutskens, S.B. · Eb, M.M. van der · Plomp, A.C. · Jonges, L.E. · Cramer, S.J. · Ensink, N.G. · Kuppen, P.J.K. · Hoeben, R.C.
Keywords: Cancer gene therapy · IL-2 · Recombinant adenovirus · complementary DNA · cytokine · recombinant interleukin 2 · tumor antigen · virus vector · Adenovirus · Animal cell · Animal experiment · Animal model · Antigen recognition · Antineoplastic activity · Cancer inhibition · Colorectal cancer · Controlled study · Delayed hypersensitivity · DNA transfer · Gene expression · Gene therapy · immune response · Immunotherapy · Liver metastasis · Lymphocyte activation · Nonhuman · Rat strain · T lymphocyte · Transgene · Tumor cell · Tumor regression · Virus plaque · Virus recombinant · Virus replication · Adenoviridae · Animals · Colorectal Neoplasms · Flow Cytometry · Gene Therapy · Genetic Vectors · Histocompatibility Antigens Class I · Histocompatibility Antigens Class II · Humans · Intercellular Adhesion Molecule-1 · Interleukin-2 · Liver Neoplasms, Experimental · Lymphocyte Activation · Rats · Rats, Inbred Strains · T-Lymphocytes · Tumor Cells, Cultured · Adenoviridae · Animalia · DNA viruses
[Abstract]

14 Involvement of Membrane-Type Matrix Metalloproteinases (MT-MMPs) in capillary tube formation by human endometrial microvascular endothelial Cells: Role of MT3-MMP
article 2004    
Author: Plaisier, M. · Kapiteijn, K. · Koolwijk, P. · Fijten, C. · Hanemaaijer, R. · Grimbergen, J.M. · Mulder-Stapel, A. · Quax, P.H.A. · Helmerhorst, F.M. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Fibrin · Gelatinase A · Immunoglobulin G · Interstitial collagenase · Matrix metalloproteinase · Matrix metalloproteinase inhibitor · Membrane type 3 metalloproteinase · Membrane type 4 metalloproteinase · Messenger RNA · Unclassified drug · Urokinase · Adenovirus · Capillary · Cell culture · Controlled study · Endometrium cell · Endothelium cell · Enzyme inhibition · Enzyme regulation · Genetic transduction · Human cell · Immunohistochemistry · Prepuce · Protein expression · Vascular endothelium · Adenoviridae · Cells, Cultured · Collagen Type I · Endometrium · Endothelial Cells · Female · Humans · Matrix Metalloproteinase 16 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Neovascularization, Physiologic · Plasmin · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Urinary Plasminogen Activator · Adenoviridae
[Abstract]

15 Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35
article 2010    
Author: Kälin, S. · Amstutz, B. · Gastaldelli, M. · Wolfrum, N. · Boucke, K. · Havenga, M. · DiGennaro, F. · Liska, N. · Hemmi, S. · Greber, U.F.
Keywords: Biology · Biomedical Research · actin · F actin · heparan sulfate · jaspamide · p21 activated kinase 1 · protein kinase C · sodium proton exchange protein · article · carboxy terminal sequence · epithelium cell · HeLa cell · hematopoietic cell · human · Human adenovirus · human cell · lung fibroblast · nonhuman · priority journal · serotype · Adenoviruses, Human · Antigens, CD46 · Cell Line · Epithelial Cells · Fibroblasts · Humans · Integrins · Pinocytosis · Receptors, Virus · Virus Internalization · Adenoviridae · Human adenovirus
[Abstract]

16 Adenovirus mediated overexpression of human phospholipid transfer protein alters plasma HDL levels in mice
article 1998    
Author: Ehnholm, S. · Dijk, K.W. van · Hof, B. van · Zee, A.D. van · Olkkonen, V.M. · Jauhiainen, M. · Hofker, M. · Havekes, L. · Ehnholm, C.
Keywords: Biology · Apolipoprotein A-I · HDL conversion · HDL metabolism · Lipid metabolism · Phospholipid transfer protein · Recombinant adenovirus · Adenoviridae · Animals · Apolipoprotein A-I · Carrier Proteins · Cholesterol · Cholesterol Esters · Female · Genetic Vectors · Humans · Lipoproteins · Lipoproteins, HDL · Liver · Membrane Proteins · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phospholipid Transfer Proteins · Phospholipids · Recombinant Proteins · Triglycerides
[PDF] [Abstract]

17 Adenoviral expression of a urokinase receptor - Targeted protease inhibitor inhibits neointima formation in murine and human blood vessels
article 2001    
Author: Quax, P.H.A. · Lamfers, M.L.M. · Lardenoye, J.H.P. · Grimbergen, J.M. · Vries, M.R. de · Slomp, J. · Ruiter, M.C. de · Kockx, M.M. · Verheijen, J.H. · Hinsbergh, V.W.M. van
Keywords: Adenoviridae · Animals · Aprotinin · Blood Vessels · Cattle · CHO Cells · Cricetinae · Femoral Artery · Femoral Vein · Gene Expression · Genetic Vectors · Humans · Mice · Mice, Inbred C57BL · Muscle, Smooth, Vascular · Organ Culture Techniques · Peptide Fragments · Plasmin · Recombinant Fusion Proteins · Saphenous Vein · Transfection · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

18 Fiber-chimeric adenoviruses expressing fibers from serotype 16 and 50 improve gene transfer to human pancreatic adenocarcinoma
article 2009    
Author: Kuhlmann, K.F.D. · Geer, M.A. van · Bakker, C.T. · Dekker, J.E.M. · Havenga, M.J.E. · Oude Elferink, R.P.J. · Gouma, D.J. · Bosma, P.J. · Wesseling, J.G.
Keywords: Biology · Biomedical Research · Adenovirus · Fiber-chimeric · Pancreatic cancer · Serotype · adenovirus vector · bacterial enzyme · coxsackie virus and adenovirus receptor · cytosine deaminase · flucytosine · green fluorescent protein · red fluorescent protein · virus DNA · virus fiber protein · Adenovirus fiber gene · Adenovirus fiber knob 5 · Adenovirus type 16 · Adenovirus type 50 · antineoplastic activity · article · bacterial gene · cancer cell culture · cell viability · controlled study · cytosine deaminase gene · drug cytotoxicity · drug efficacy · drug mechanism · drug specificity · fiber chimeric human adenovirus 5 · gene directed enzyme prodrug therapy · gene expression · gene targeting · human · Human adenovirus · Human adenovirus 5 · human cell · human tissue · liver cell culture · molecular cloning · nonhuman · pancreas adenocarcinoma · priority journal · protein domain · protein expression · suicide gene · viral gene delivery system · virus fiber · virus gene · Adenoviridae · Cell Line · Cell Line, Tumor · Flow Cytometry · Gene Therapy · Genetic Vectors · Green Fluorescent Proteins · Humans · Pancreatic Neoplasms · Polymerase Chain Reaction · Recombinant Fusion Proteins · Recombination, Genetic · Transduction, Genetic · Viral Envelope Proteins · Adenoviridae
[Abstract]

19 Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1
article 2002    
Author: Lamfers, M.L.M. · Grimbergen, J.M. · Aalders, M.C. · Havenga, M.J. · Vries, M.R. de · Huisman, L.G.M. · Hinsbergh, V.W.M. van · Quax, P.H.A.
Keywords: Biology · Adenovirus · Matrix metalloproteinases · Neointima formation · Plasmin(ogen) · Urokinase-type plasminogen activator · Adenovirus · Adenoviridae · Animals · Cell Division · Cell Membrane · Cell Movement · Cells, Cultured · CHO Cells · Collagenases · Cricetinae · Culture Media, Conditioned · Enzyme Activation · Flow Cytometry · Gene Transfer Techniques · Humans · Matrix Metalloproteinase 13 · Muscle, Smooth, Vascular · Protein Structure, Tertiary · Receptors, Cell Surface · Recombinant Fusion Proteins · RNA, Messenger · Saphenous Vein · Tissue Inhibitor of Metalloproteinase-1 · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

20 Induction of atherosclerotic plaque rupture in apolipoprotein E-/- mice after adenovirus-mediated transfer of p53
article 2002    
Author: Thüsen, J.H. von der · Vlijmen, B.J.M. van · Hoeben, R.C. · Kockx, M.M. · Havekes, L.M. · Berkel, T.J.C. van · Biessen, E.A.L.
Keywords: Health · Carotid arteries · Genes · Muscle · Adenovirus vector · Apolipoprotein E · Beta galactosidase · Phenylephrine · Protein p53 · Animal experiment · Animal model · Atherogenesis · Atherosclerotic plaque · Carotid artery · Cell death · Controlled study · Gene overexpression · Genetic transfection · Knockout mouse · Mouse · Nonhuman · Rupture · Smooth muscle fiber · Thrombosis · Transgene · Tumor suppressor gene · Adenoviridae · Animals · Apolipoproteins E · Apoptosis · Arteriosclerosis · beta-Galactosidase · Biological Markers · Carotid Artery Diseases · Cell Division · Genetic Vectors · Immunohistochemistry · Mice · Mice, Knockout · Muscle, Smooth, Vascular · Transfection · Tumor Suppressor Protein p53
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 28 found. Next | Sort by date