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1 Pulmonary effects of ultrafine and fine ammonium salts aerosols in healthy and monocrotaline-treated rats following short-term exposure
article 2002    
Author: Cassee, F.R. · Arts, J.H.E. · Fokkens, P.H.B. · Spoor, S.M. · Boere, A.J.F. · Bree, L. van · Dormans, J.A.M.A.
Keywords: Nutrition · Administration, Inhalation · Aerosols · Air Pollutants · Ammonium Sulfate · Animals · Bronchoalveolar Lavage Fluid · Ferrous Compounds · Hypertension, Pulmonary · Lung · Macrophages, Alveolar · Male · Monocrotaline · Nitrates · Particle Size · Quaternary Ammonium Compounds · Rats · Rats, Sprague-Dawley · Animalia · Haemophilus · Haemophilus sp.
[Abstract]

2 Evaluation of the sensory irritation test (alarie test) for the assessment of respiratory tract irritation
article 2002    
Author: Bos, P.M.J. · Busschers, M. · Arts, J.H.E.
Keywords: Environment · Administration, Inhalation · Air Pollutants · Animals · Bronchial Hyperreactivity · Dose-Response Relationship, Drug · Irritants · Mice · Models, Animal · Nasal Mucosa · Rats · Rats, Wistar · Reproducibility of Results · Respiratory Tract Diseases · Sensation · Sensitivity and Specificity · Species Specificity · Animalia
[Abstract]

3 Toxicology of chemical mixtures : challenges for today and the future
article 1995    
Author: Feron, V.J. · Groten, J.P. · Jonker, D. · Cassee, F.R. · Bladeren, P.J. van
Keywords: Toxicology · Administration, Inhalation · Administration, Oral · Aldehydes · Animals · Drug Interactions · Hazardous Substances · Kidney Diseases · Organ Specificity · Rats · Rats, Wistar · Research Design · Risk Assessment · Toxicity Tests · Xenobiotics · Animalia · Complex mixtures · Defined · Standard setting · Study designs
[Abstract]

4 Effect of variable versus fixed exposure levels on the toxicity of acetaldehyde in rats
article 1986    
Author: Appelman, L.M. · Woutersen, R.A. · Feron, V.J. · Hooftman, R.N. · Notten, W.R.F.
Keywords: Acetaldehyde · Animal experiment · Inhalation · Intoxication · Lung alveolus macrophage · Lung toxicity · Nonhuman · Nose mucosa · Olfactory epithelium · Olfactory system · Phagocytosis · Rat · Respiratory system · Acetaldehyde · Administration, Inhalation · Animal · Drug Administration Schedule · Lung · Male · Nasal Mucosa · Phagocytosis · Rats · Rats, Inbred Strains
[Abstract]

5 Approaches to induce and elicit respiratory allergy: Impact of route and intensity of exposure
article 2003    
Author: Arts, J.H.E. · Kuper, C.F.
Keywords: Toxicology Health · Toxicology and Applied Pharmacology · Airway irritation · Respiratory allergy · Route and intensity of exposure · allergen · irritant agent · allergic reaction · biosafety · conference paper · environmental factor · exposure · heredity · human · inhalation test · nonhuman · prediction · priority journal · respiratory tract allergy · risk assessment · risk management · sensitization · standardization · Administration, Cutaneous · Administration, Inhalation · Allergens · Animals · Dose-Response Relationship, Drug · Predictive Value of Tests · Respiratory System · Animalia
[Abstract]

6 Respiratory irritation by trimellitic anhydride in Brown Norway and Wistar rats
article 2001    
Author: Arts, J.H.E. · Koning, M.W.de · Bloksma, N. · Kuper, C.F.
Keywords: trimellitic anhydride · animal experiment · article · breathing pattern · concentration response · controlled study · female · lung function · lung weight · nonhuman · priority journal · rat · rat strain · respiratory tract allergy · statistical analysis · Administration, Inhalation · Algorithms · Anhydrides · Animals · Female · Immunoglobulin E · Irritants · Lung · Metals · Organ Size · Particle Size · Rats · Rats, Inbred BN · Rats, Wistar · Respiratory Function Tests · Respiratory Tract Diseases · Animalia · Rattus norvegicus
[Abstract]

7 Adherence to inhaled corticosteroids in children with asthma and their parents
article 2006    
Author: Dellen, Q.M. van · Stronks, K. · Bindels, P.J.E. · Öry, F.G. · Aalderen, W.M.C. van
Keywords: Health · Adherence · Children · Inhaled corticosteroids · Parents · Corticosteroid · Adolescent · Disease association · Health program · Major clinical study · Medical education · Patient assessment · School child · Self report · Administration, Inhalation · Adolescent · Adrenal Cortex Hormones · Adult · Anti-Asthmatic Agents · Asthma · Attitude · Child · Female · Health Knowledge, Attitudes, Practice · Humans · Male · Metered Dose Inhalers · Multivariate Analysis · Netherlands · Parenting · Parents · Patient Compliance · Questionnaires
[Abstract]

8 Inhaled formaldehyde: Evaluation of sensory irritation in relation to carcinogenicity
article 2006    
Author: Arts, J.H.E. · Rennen, M.A.J. · Heer, C.de
Keywords: Health · Toxicology and Applied Pharmacology · Benchmark dose · Carcinogenicity · Formaldehyde · Sensory irritation · formaldehyde · article · carcinogenicity · computer program · eye irritation · human · nonhuman · nose injury · nose irritation · odor · priority journal · rating scale · respiratory tract disease · sense organ · smelling · symptomatology · Administration, Inhalation · Air Pollutants · Animals · Carcinogens · Carcinoma · Eye · Formaldehyde · Humans · Inhalation Exposure · Irritants · Nasal Mucosa · No-Observed-Adverse-Effect Level · Nose Neoplasms · Occupational Exposure · Pharynx · Risk Assessment · Animalia
[Abstract]

9 Setting an indoor air exposure limit for formaldehyde: Factors of concern
article 2008    
Author: Arts, J.H.E. · Muijser, H. · Kuper, C.F. · Woutersen, R.A.
Keywords: Health · Toxicology and Applied Pharmacology · Exposure limit · Formaldehyde · Indoor air · Sensory irritation · Air quality standard · Ambient air · Environmental exposure · Eye irritation · Nose irritation · Throat irritation · Administration, Inhalation · Air Pollutants · Carcinogens · Child · European Union · Eye · Formaldehyde · Humans · Inhalation Exposure · Irritants · No-Observed-Adverse-Effect Level · Nose · Occupational Exposure · Pharynx · Trigeminal Nerve
[Abstract]

10 Allergic inflammation in the upper respiratory tract of the rat upon repeated inhalation exposure to the contact allergen dinitrochlorobenzene (DNCB).
article 2010    
Author: Triel, J.J. van · Arts, J.H. · Muijser, H. · Kuper, C.F.
Keywords: Chemistry · 1 chloro 2,4 dinitrobenzene · allergen · autacoid · animal · article · breathing mechanics · comparative study · drug effect · exposure · female · immunology · inhalational drug administration · pathology · pathophysiology · rat · respiratory system · skin allergy · Wistar rat · Administration, Inhalation · Allergens · Animals · Dermatitis, Allergic Contact · Dinitrochlorobenzene · Female · Inflammation Mediators · Inhalation Exposure · Rats · Rats, Wistar · Respiratory Mechanics · Respiratory System
[Abstract]

11 The ototoxic effects of ethyl benzene in rats
article 1999    
Author: Cappaert, N.L.M. · Klis, S.F.L. · Muijser, H. · Groot, J.C.M.J. de · Kulig, B.M. · Smoorenburg, G.F.
Keywords: Nutrition · Electrocochleography · Ethyl benzene · Histology · Ototoxicity · Rat · Reflex modification audiometry · Ethylbenzene · Organic solvent · Animal experiment · Animal model · Animal tissue · Article · Audiometry · Cochlea · Controlled study · Electrocochleography · Hair cell · Hearing loss · Histology · Male · Morphology · Nonhuman · Ototoxicity · Priority journal · Rat · Administration, Inhalation · Animals · Audiometry · Audiometry, Evoked Response · Auditory Threshold · Benzene Derivatives · Deafness · Ear, Inner · Hair Cells, Outer · Humans · Male · Rats · Rats, Wistar · Solvents
[Abstract]

12 Low level nose-only exposure to the nerve agent soman: Toxicokinetics of soman stereoisomers and cholinesterase inhibition in atropinized guinea pigs
article 1998    
Author: Benschop, H.P. · Trap, H.C. · Spruit, H.E.T. · Wiel, H.J. van der · Langenberg, J.P. · Jong, L.P.A. de
Keywords: Perception · Atropine · Carboxylesterase · Cholinesterase · Animal cell · Blood level · Enzyme inhibition · Exposure · Guinea pig · Inhalation · Male · Neurotoxicity · Nonhuman · Stereoisomerism · Toxicokinetics · Administration, Inhalation · Animals · Carboxylic ester hydrolases · Chemical warfare agents · Dose-response relationship · Drugs · Erythrocytes · Soman · Stereoisomerism · Time factors · Atropine, 51-55-8 · Carboxylesterase, EC 3.1.1.1 · Carboxylic ester hydrolases, EC 3.1.1.- · Soman, 96-64-0
[Abstract]

13 Application of physiologically based toxicokinetic modelling to study the impact of the exposure scenario on the toxicokinetics and the behavioural effects of toluene in rats
article 2003    
Author: Asperen, J. van · Rijcken, W.R.P. · Lammers, J.H.C.M.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Peak exposure · Physiologically based toxicokinetic modelling · Rat · Toluene · toluene · animal experiment · area under the curve · article · behavior · blood level · brain level · concentration response · controlled study · exposure · male · model · nonhuman · prediction · priority journal · rat · reliability · task performance · tissue level · toxicokinetics · visual discrimination · Administration, Inhalation · Animals · Behavior, Animal · Brain · Discrimination Learning · Dose-Response Relationship, Drug · Inhalation Exposure · Models, Biological · Rats · Toluene · Visual Perception
[Abstract]

14 Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteers
article 2004    
Author: Kezic, S. · Meuling, W.J.A. · Jakasa, I.
Keywords: Health · Physiological Sciences · 2-Butoxyacetic acid · 2-Butoxyethanol · Dermal exposure · Skin absorption · 2 butoxyacetic acid · 2 butoxyethanol · acetic acid derivative · biochemical marker · unclassified drug · adult · aqueous solution · article · blood level · calculation · conjugation · controlled study · dermis · environmental exposure · forearm · half life time · human · human experiment · inhalation · kinetics · male · mouth · normal human · sampling · urinalysis · urinary excretion · urine level · volunteer · Administration, Cutaneous · Administration, Inhalation · Adult · Ethylene Glycols · Glycolates · Half-Life · Humans · Male · Middle Aged · Skin Absorption
[Abstract]

15 Oral-to-inhalation route extrapolation in occupational health risk assessment: A critical assessment
article 2004    
Author: Rennen, M.A.J. · Bouwman, T. · Wilschut, A. · Bessems, J.G.M. · Heer, C.de
Keywords: Health Chemistry · Food and Chemical Risk Analysis · Inhalation · Local effects · Oral · Respiratory · Risk assessment · Route extrapolation · Accuracy · Analytical error · Data base · Inhalation · Intermethod comparison · Occupational exposure · Occupational hazard · Priority journal · Quantitative analysis · Reliability · Risk assessment · Screening test · Administration, Inhalation · Administration, Oral · Animals · Dose-Response Relationship, Drug · Humans · Models, Biological · No-Observed-Adverse-Effect Level · Occupational Exposure · Pesticides · Predictive Value of Tests · Research Design · Risk Assessment · Species Specificity
[Abstract]

16 Subacute (28-day) toxicity of furfural in Fischer 344 rats: A comparison of the oral and inhalation route
article 2004    
Author: Arts, J.H.E. · Muijser, H. · Appel, M.J. · Kuper, C.F. · Bessems, J.G.M. · Woutersen, R.A.
Keywords: Biology Health · Toxicology and Applied Pharmacology · Fischer rat · Furfural · Inhalation · Oral · Route-to-route extrapolation · Subacute toxicity · corn oil · furfural · air · animal experiment · animal model · animal tissue · article · comparative study · concentration response · controlled study · exposure · female · histopathology · kidney mass · liver weight · male · mortality · nonhuman · olfactory epithelium · rat · survival · toxicity testing · Administration, Inhalation · Administration, Oral · Animals · Dose-Response Relationship, Drug · Female · Furaldehyde · Kidney · Liver · Longevity · Male · No-Observed-Adverse-Effect Level · Olfactory Mucosa · Organ Size · Rats · Rats, Inbred F344 · Zea mays
[Abstract]

17 Intravenous and inhalation toxicokinetics of sarin stereoisomers in atropinized guinea pigs
article 2000    
Author: Spruit, W.E.T. · Langenberg, J.P. · Trap, H.C. · Wiel, H.J. van der · Helmich, R.B. · Helden, H.P.M. van · Benschop, H.P.
Keywords: Acetylcholinesterase inhibition · Guinea pig · Intravenous bolus · Nose-only exposure · Respiratory parameters · Stereoisomers · Toxicokinetics · Animal experiment · Animal model · Binding site · Chemical warfare · Controlled study · Drug absorption · Drug elimination · Enzyme inhibition · Gas chromatography · Guinea pig · Nonhuman · Nose mucosa · Stereoisomerism · Toxicokinetics · Acetylcholinesterase · Administration, Inhalation · Animals · Area Under Curve · Atropine · Chemical Warfare Agents · Guinea Pigs · Injections, Intravenous · Male · Stereoisomerism · Acetylcholinesterase, EC 3.1.1.7 · Atropine, 51-55-8 · Chemical warfare agents · Sarin, 107-44-8
[Abstract]

18 Changes in the nasal epithelium of rats exposed by inhalation to mixtures of formaldehyde, acetaldehyde, and acrolein
article 1996    
Author: Cassee, F.R. · Groten, J.P. · Feron, V.J.
Keywords: Biology · acetaldehyde · acrolein · aldehyde dehydrogenase · formaldehyde · glutathione peroxidase · glutathione reductase · glutathione transferase · animal experiment · animal model · animal tissue · article · cell proliferation · chemical interaction · controlled study · histopathology · inhalation · male · nonhuman · nose mucosa · olfactory epithelium · rat · respiratory epithelium · upper respiratory tract · Acetaldehyde · Acrolein · Administration, Inhalation · Air Pollutants · Aldehyde Dehydrogenase · Animals · Antigens, Nuclear · Autopsy · Biological Markers · Biotransformation · Bromodeoxyuridine · Cell Division · Dose-Response Relationship, Drug · Epithelial Cells · Epithelium · Formaldehyde · Gene Expression Regulation · Male · Nasal Mucosa · Nuclear Proteins · Rats · Rats, Wistar · Staining and Labeling
[Abstract]

19 Subacute toxicity of a mixture of nine chemicals in rats: Detecting interactive effects with a fractionated two-level factorial design
article 1997    
Author: Groten, J.P. · Schoen, E.D. · Bladeren, P.J. van · Kuper, C.F. · Zorge, J.A. van · Feron, V.J.
Keywords: Acetylsalicylic acid · Butylated hydroxyanisole · Cadmium chloride · Dichloromethane · Formaldehyde · Loperamide · Phthalic acid bis(2 ethylhexyl) ester · Spermine · Stannous chloride · Animal experiment · Controlled study · Drug mixture · Factorial analysis · Male · Model · Nonhuman · Oral drug administration · Prognosis · Rat · Risk assessment · Theory · Toxicity · Administration, Inhalation · Animals · Blood Chemical Analysis · Body Weight · Drug Combinations · Drug Interactions · Epithelium · Hazardous Substances · Hematologic Tests · Hypertrophy · Liver · Male · Models, Statistical · Multiple Chemical Sensitivity · Nasal Cavity · No-Observed-Adverse-Effect Level · Organ Size · Rats · Rats, Wistar
[Abstract]

20 Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats: Combination of findings from two bioassays
article 2001    
Author: Feron, V.J. · Kittel, B. · Kuper, C.F. · Ernst, H. · Rittinghausen, S. · Muhle, H. · Koch, W. · Gamer, A. · Mallett, A.K. · Hoffmann, H.D.
Keywords: Combined long-term rat bioassays · Inhalation · Methylene diphenyl diisocyanate (MDI) · Pulmonary effects · Carbenoid · Cyanic acid derivative · Animal experiment · Bioassay · Carcinogenicity · Exposure · Female · Fibrosing alveolitis · Histopathology · Hyperplasia · Inflammation · Lung adenoma · Lung injury · Lung toxicity · Lung weight · Male · Nonhuman · Priority journal · Rat · Risk assessment · Adenoma · Administration, Inhalation · Aerosols · Animals · Body Weight · Carcinogens · Chronic Disease · Dose-Response Relationship, Drug · Female · Hyperplasia · Inhalation Exposure · Isocyanates · Longevity · Lung Neoplasms · Male · Organ Size · Pulmonary Fibrosis · Rats · Rats, Wistar
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 26 found. Next | Sort by date