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1 Genetic modulation of coagulation factor VII plasma levels : Contribution of different polymorphisms and gender-related effects
article 1998    
Author: Di Castelnuovo, A. · D'Orazio, A. · Amore, C. · Falanga, A. · Kluft, C. · Donati, M.B. · Lacoviello, L.
Keywords: Biology · Adult · Alleles · Factor VII · Female · Humans · Italy · Male · Middle Aged · Polymorphism, Genetic · Sex Factors
[Abstract]

2 Association between polymorphisms in the fibrinogen α- and β-genes on the post-trauma fibrinogen increase
article 1998    
Author: Ferrer-Antunes, C. · Maat, M.P.M. de · Palmeiro, A. · Pimentel, J. · Fernandes, V.
Keywords: Health · Adult · Aged · Alleles · Craniocerebral Trauma · Female · Fibrinogen · Gene Frequency · Genotype · Humans · Male · Middle Aged · Polymorphism, Genetic · Thoracic Injuries
[Abstract]

3 Apolipoprotein E phenotype is not related to late-life depression in a population-based sample
article 1998    
Author: Schmand, B. · Hooijer, C. · Jonker, C. · Lindeboom, J. · Havekes, L.M.
Keywords: Health · Aged · Aged, 80 and over · Alleles · Analysis of Variance · Apolipoproteins A · Chi-Square Distribution · Depression · Female · Genetics, Population · Humans · Likelihood Functions · Male · Netherlands · Phenotype · Regression Analysis
[Abstract]

4 Association between apolipoprotein E ε4 and the rate of cognitive decline in community-dwelling elderly individuals with and without dementia
article 1998    
Author: Jonker, C. · Schmand, B. · Lindeboom, J. · Havekes, L.M. · Launer, L.J.
Keywords: Health · Aged · Aged, 80 and over · Alleles · Apolipoproteins E · Cognition · Dementia · Female · Humans · Longitudinal Studies · Male · Neuropsychological Tests · Phenotype · Residence Characteristics · Severity of Illness Index
[Abstract]

5 A genetic association study of the IGF-1 gene and radiological osteoarthritis in a population-based cohort study (the Rotterdam study)
article 1998    
Author: Meulenbelt, I. · Bijkerk, C. · Miedema, H.S. · Breedveld, F.C. · Hofman, A. · Valkenburg, H.A. · Pols, H.A.P. · Slagboom, P.E. · Duijn, C.M. van
Keywords: Health · Aged · Alleles · Body Mass Index · Bone Density · Female · Genotype · Humans · Insulin-Like Growth Factor I · Male · Middle Aged · Osteoarthritis · Prospective Studies
[Abstract]

6 Plasma levels of apolipoprotein E and risk of stroke in old age
bookPart 2007    
Author: Vliet, P. van · Mooijaart, S.P. · Craen, A.J.M. de · Rensen, P.C.N. · Heemst, D. van · Westendorp, R.G.J.
Keywords: Biology · Biomedical Research · Atherosclerosis · Elderly · Plasma apolipoprotein E levels · Stroke · Aged, 80 and over · Alleles · Apolipoproteins E · Atherosclerosis · Cerebrovascular Accident · Cerebrovascular Disorders · Female · Genetic Predisposition to Disease · Genotype · Humans · Ischemia · Male · Risk · Risk Factors
[Abstract]

7 Apolipoprotein E genotype and concomitant clinical features in early-onset Alzheimer's disease
article 1996    
Author: Bronzova, J. · Duijn, C.M. van · Havekes, L.M. · Knijff, P. de · Broeckhoven, C. van · Hofman, A.
Keywords: Biology · Apolipoprotein E gene · Apolipoprotein e · Apolipoprotein e4 · Adult · Allele · Clinical feature · Disease course · Genotype · Major clinical study · Myoclonus · Rigidity · Risk · Seizure · Tremor · Alleles · Alzheimer Disease · Apolipoproteins · Female · Humans · Male · Middle Aged · Prognosis
[Abstract]

8 A specific allele of the histidine-rich glycoprotein (HRG) locus is linked with elevated plasma levels of HRG in a Dutch family with thrombosis
article 1995    
Author: Hennis, B.C. · Boheemen, P.A. van · Koeleman, B.P.C. · Boomsma, D.I. · Engesser, L. · Wees, A.G.M. van · Novakova, I. · Brommer, E.J.P. · Kluft, C.
Keywords: Biology · Aged · Alleles · Base Sequence · Blood Coagulation · Female · Glycoproteins · Human · Linkage (Genetics) · Male · Middle Age · Molecular Sequence Data · Pedigree · Polymorphism (Genetics) · Proteins · Repetitive Sequences, Nucleic Acid · Support, Non-U.S. Gov't · Thrombosis
[Abstract]

9 Lipid profiles reflecting high and low risk for coronary heart disease : Contribution of apolipoprotein E polymorphism and lifestyle
article 1998    
Author: Boer, J.M.A. · Feskens, E.J.M. · Schouten, E.G. · Havekes, L.M. · Seidell, J.C. · Kromhout, D.
Keywords: Health · Apolipoprotein E polymorphism · HDL-cholesterol · Lipid profile · Modifiable risk factors · Total cholesterol · Adult · Alleles · Apolipoproteins E · Cholesterol · Cholesterol, HDL · Coronary Disease · Female · Humans · Life Style · Lipids · Male · Middle Aged · Odds Ratio · Phenotype · Polymorphism, Genetic · Risk Factors
[Abstract]

10 Apolipoprotein E2 (Lys146→Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides
article 2000    
Author: Beer, F. de · Dijk, K.W. van · Jong, M.C. · Vark, L.C. van · Zee, A. van der · Hofker, M.H. · Fallaux, F.J. · Hoeben, R.C. · Smelt, A.H.M. · Havekes, L.M.
Keywords: Adenoviridae · Alleles · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Gene Expression · Gene Transfer Techniques · Humans · Hydrolysis · Hyperlipoproteinemia Type III · Hypertriglyceridemia · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · Point Mutation · RNA, Messenger · Triglycerides
[Abstract]

11 Apolipoprotein A-IV polymorhism and its effect on plasma lipid and apolipoprotein concentrations
article 1988    
Author: Knijff, P. de · Rosseneu, M. · Beisiegel, U. · Keersgieter, W. de · Frants, R.R. · Havekes, L.M.
Keywords: Biology · Triacylglycerol · Apolipoprotein blood level · Heredity · Lipid blood level · Population genetics · Protein polymorphism · Blood · Genetic polymorphism · Genetics · Phenotype · Adult · Alleles · Animal · Apolipoproteins · Apolipoproteins A · Apolipoproteins B · Cholesterol · Gene Frequency · Human · Lipids · Male · Phenotype · Polymorphism (Genetics) · Rabbits · Triglycerides
[PDF] [Abstract]

12 Familial dysbetalipoproteinemia associated with apolipoprotein E3-Leiden in an extended multigeneration pedigree
article 1991    
Author: Knijff, P. de · Maagdenberg, A.M.J.M. van den · Stalenhoef, A.F.H. · Leuven, J.A.G. · Demacker, P.N.M. · Kuyt, L.P. · Frants, R.R. · Havekes, L.M.
Keywords: Adolescent · Adult · Age Factors · Aged · Alleles · Apolipoproteins E · Body Weight · Cholesterol · Female · Heterozygote · Heterozygote Detection · Human · Hyperlipoproteinemia Type III · Lipoproteins · Lipoproteins, VLDL Cholesterol · Male · Middle Age · Pedigree · Sex Factors · Support, Non-U.S. Gov't
[PDF] [Abstract]

13 Structural and functional analysis of the S-layer protein crystallisation domain of Lactobacillus acidophilus ATCC 4356 : evidence for protein : protein interaction of two subdomains
article 2002    
Author: Smit, E. · Jager, D. · Martinez, B. · Tielen, F.J. · Pouwels, P.H.
Keywords: Biology · Bacteria (microorganisms) · Escherichia coli · Lactobacillus · Lactobacillus acidophilus · Alleles · Amino Acid Sequence · Bacterial Proteins · Binding Sites · Chromosomes, Bacterial · Crystallization · Epitopes · Escherichia coli · Genes, myc · Genetic Vectors · Lactobacillus acidophilus · Lactobacillus casei · Membrane Glycoproteins · Membrane Proteins · Molecular Sequence Data · Molecular Weight · Mutagenesis, Site-Directed · Peptide Fragments · Protein Binding · Protein Structure, Secondary · Protein Structure, Tertiary · Proto-Oncogene Proteins c-myc · Recombinant Proteins · Recombination, Genetic · Transformation, Bacterial · Vaccines
[Abstract]

14 An amino acid polymorphism in histidine-rich glycoprotein (HRG) explains 59% of the variance in plasma HRG levels
article 1995    
Author: Hennis, B.C. · Boomsma, D.I. · Boheemen, P.A. van · Engesser, L. · Kievit, P. · Dooijewaard, G. · Kluft, C.
Keywords: Biology · glycoprotein · histidine · adult · age · article · blood level · controlled study · environmental factor · genetic polymorphism · human · inheritance · major clinical study · maximum likelihood method · normal human · pedigree · priority journal · Alleles · Amino Acids · Analysis of Variance · Blood Proteins · Case-Control Studies · Chromosome Mapping · Glycoproteins · Humans · Likelihood Functions · Molecular Weight · Pedigree · Phenotype · Polymorphism, Genetic · Proteins
[Abstract]

15 Coagulation factor VII, serum-triglycerides and the R/Q353 polymorphism: Differences between older men and women
article 1997    
Author: Mennen, L.I. · Maat, M.P.M. de · Schouten, E.G. · Kluft, C. · Jong, P.T.V.M. de · Hofman, A. · Grobbee, D.E.
Keywords: Biology · Blood clotting factor 7 · Triacylglycerol · Adult · Aged · Allele · Cardiovascular risk · Controlled study · Genetic association · Genetic polymorphism · Genotype · Human cell · Major clinical study · Regression analysis · Sex difference · Triacylglycerol blood level · Aging · Alleles · Factor VII · Female · Genotype · Humans · Male · Middle Aged · Polymorphism, Genetic · Sex Characteristics · Triglycerides
[Abstract]

16 Apolipoprotein e4 allele and cognitive decline in elderly men
article 1994    
Author: Feskens, E.J.M. · Havekes, L.M. · Kalmijn, S. · Knijff, P. de · Launer, L.J. · Kromhout, D.
Keywords: Biology · cognition · cognitive defect · disease predisposition · follow up · mental health · phenotype · prediction · priority journal · protein polymorphism · risk factor · Aged · Aged, 80 and over · Alleles · Apolipoproteins E · Cognition Disorders · Cohort Studies · Human · Incidence · Male · Netherlands · Odds Ratio · Polymorphism (Genetics) · Prevalence · Risk Factors · Support, Non-U.S. Gov't · Support, U.S. Gov't, P.H.S.
[Abstract]

17 Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels
article 1994    
Author: Knijff, P. de · Maagdenberg, A.M.J.M. van den · Frants, R.R. · Havekes, L.M.
Keywords: Biology · Apolipoprotein (apo) E · Atherosclerosis · Familial Dysbetalipoproteinemia (FD) · Mutations · Polymorphisms · Type III Hyperlipoproteinemia · Cholesterol · Chylomicron · Low density lipoprotein receptor · Triacylglycerol · Very low density lipoprotein · Alzheimer disease · Atherosclerosis · Cholesterol blood level · Coronary artery disease · Creutzfeldt jakob disease · Gene mutation · Genetic heterogeneity · Genetic linkage · Genetic polymorphism · Ligand binding · Lipoprotein metabolism · Alleles · Amino Acid Sequence · Base Sequence · DNA · Female · Gene Frequency · Human · Hyperlipidemia · Hyperlipoproteinemia Type III · Lipids · Lipoproteins · Male · Molecular Sequence Data · Mutation · Variation (Genetics)
[Abstract]

18 Gender-related association between β-fibrinogen genotype and plasma fibrinogen levels and linkage disequilibrium at the fibrinogen locus in Greenland Inuit
article 1995    
Author: Maat, M.P.M. de · Knijff, P. de · Green, F.R. · Thomas, A.E. · Jespersen, J. · Kluft, C.
Keywords: Biology · cardiovascular risk · DNA polymorphism · fibrinogen · indicators · Inuit · acute phase response · allele · coronary risk · disease association · dna polymorphism · female · fibrinogen blood level · gene linkage disequilibrium · gene locus · genotype · greenland · human · major clinical study · promoter region · sex difference · Adult · Alleles · Body Mass Index · C-Reactive Protein · Deoxyribonucleases, Type II Site-Specific · Eskimos · Female · Fibrinogen · Genotype · Greenland · Human · Linkage Disequilibrium · Male · Mongoloid Race · Polymorphism, Restriction Fragment Length · Sex Characteristics · Smoking
[Abstract]

19 Plasma apoAV levels are markedly elevated in severe hypertriglyceridemia and positively correlated with the APOA5 S19W polymorphism
article 2007    
Author: Henneman, P. · Schaap, F.G. · Havekes, L.M. · Rensen, P.C.N. · Frants, R.R. · Tol, A. van · Hattori, H. · Smelt, A.H.M. · Dijk, K.W. van
Keywords: Biology · Biomedical Research · apoAV · Hypertriglyceridemia · Lipoprotein lipase · Plasma apoAV concentration · SNP-analysis · apolipoprotein A5 · adult · allele · article · circulation · controlled study · endoplasmic reticulum · female · gene frequency · gene mutation · genetic polymorphism · genetic variability · haplotype · human · hypertriglyceridemia · lipolysis · major clinical study · male · priority journal · protein secretion · single nucleotide polymorphism · Adult · Alleles · Apolipoproteins A · Base Sequence · Case-Control Studies · DNA Primers · Female · Gene Frequency · Haplotypes · Humans · Hypertriglyceridemia · Male · Middle Aged · Polymorphism, Single Nucleotide
[Abstract]

20 Tumor necrosis factor-α plays an important role in restenosis development
article 2005    
Author: Monraats, P.S. · Pires, N.M.M. · Schepers, A. · Agema, W.R.P. · Boesten, L.S.M. · Vries, M.R. de · Zwinderman, A.H. · Maat, M.P.M. de · Doevendans, P.A.F.M. · Winter, R.J. de · Tio, R.A. · Waltenberger, J. · Hart, L.M. 't · Frants, R.R. · Quax, P.H.A. · Vlijmen, B.J.M. van · Havekes, L.M. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology Health · Biomedical Research · Haplotype · TNFα · Transgenic mice · Apolipoprotein E3 · Messenger RNA · Thalidomide · Tumor necrosis factor alpha · Adult · Aged · Angiography · Animal experiment · Animal model · Clinical practice · Disease marker · Drug delivery system · Genetic polymorphism · Heredity · Knockout mouse · Nonhuman · Percutaneous coronary intervention · Restenosis · Risk assessment · Screening · Aged · Alleles · Angina Pectoris · Angiography · Angioplasty, Transluminal, Percutaneous Coronary · Animals · Constriction, Pathologic · Coronary Angiography · Coronary Disease · Coronary Restenosis · Disease Models, Animal · Female · Femoral Artery · Gene Expression Regulation, Neoplastic · Genetic Predisposition to Disease · Genotype · Haplotypes · Humans · Inflammation · Ischemia · Linkage Disequilibrium · Male · Mice · Mice, Knockout · Mice, Transgenic · Middle Aged · Multivariate Analysis · Odds Ratio · Polymorphism, Genetic · Regression Analysis · Reverse Transcriptase Polymerase Chain Reaction · Risk Factors · RNA, Messenger · Thalidomide · Treatment Outcome · Tumor Necrosis Factor-alpha · Up-Regulation · Animalia · Mus musculus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 22 found. Next | Sort by date