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Showing 1 to 16 of 16 found. | Sort by date

1 Encephalitogenic and immunogenic potential of the stress protein αB-crystallin in Biozzi ABH (H-2A(g7)) mice
article 2000    
Author: Thoua, N.-M. · Noort, J.M. van · Baker, D. · Bose, A. · Sechel, A.C. van · Stipdonk, M.J.B. van · Travers, P.J. · Amor, S.
Keywords: Health · αB-Crystallin · Experimental allergic encephalomyelitis · Multiple sclerosis · Peptide epitopes, tolerance · Alpha crystallin · Antigen · Beta crystallin · Epitope · Myelin · Allergic encephalomyelitis · Animal cell · Animal experiment · Animal model · Animal tissue · Autoimmunity · Immunological tolerance · Lymphoid tissue · Multiple sclerosis · Nonhuman · Protein expression · T lymphocyte activation · Animals · Cattle · Crystallins · Encephalitis · Epitopes · Lymphoid Tissue · Mice · Mice, Mutant Strains · Models, Chemical · Molecular Conformation · Peptide Mapping · T-Lymphocytes
[Abstract]

2 Role of Th1 and Th2 cells in autoimmune demyelinating disease
article 1998    
Author: Nagelkerken, L.
Keywords: Health · Antigen-presenting cells · Cytokines · Experimental allergic encephalomyelitis · Glucocorticoids · Multiple sclerosis · Th1 cells · Th1 cell · Th2 cell · Animals · Autoimmune Diseases · Demyelinating Diseases · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Humans · Multiple Sclerosis
[PDF] [Abstract]

3 Orally administered Lactobacillus strains differentially affect the direction and efficacy of the immune response
article 1998    
Author: Maassen, C.B.M. · Holten, J.C.A.M. van · Balk, F. · Heijne den Bak-Glashouwer, M.J. · Leer, R. · Laman, J.D. · Boersma, W.J.A. · Claassen, E.
Keywords: Nutrition · lactobacillus vaccine · allergic encephalomyelitis · animal model · antibody blood level · conference paper · cytokine production · immune response · immunization · immunohistochemistry · lactobacillus · nonhuman · rat · Adjuvants, Immunologic · Administration, Oral · Animals · Antibody Formation · Cytokines · Encephalomyelitis, Autoimmune, Experimental · Female · gamma-Globulins · Intestine, Small · Lactobacillus · Mice · Mice, Inbred BALB C · Picrates · Probiotics · Cytokines · gamma-Globulins · Picrates · picric acid, 88-89-1
[Abstract]

4 Instruments for oral disease-intervention strategies : recombinant Lactobacillus casei expressing tetanus toxin fragment C for vaccination or myelin proteins for oral tolerance induction in multiple sclerosis
article 1999    
Author: Maassen, C.B.M. · Laman, J.D. · Heijne den Bak-Glashouwer, M.J. · Tielen, F.J. · Holten-Neelen, J.C.P.A. van · Hoogteijling, L. · Antonissen, C. · Leer, R.J. · Pouwels, P.H. · Boersma, W.J.A. · Shaw, D.M.
Keywords: Experimental autoimmune/allergic encephalomyelitis (EAE) · Heterologous gene expression · Mucosal vaccines · lactobacillus vaccine · Myelin protein · Recombinant vaccine · Antibody response · Immunization · Immunoblotting · Immunogenicity · Nonhuman · Oral drug administration · Priority journal · Tetanus · Vaccination · Administration, Oral · Animals · Bacterial Vaccines · Cattle · Flow Cytometry · Genetic Vectors · Guinea Pigs · Humans · Immune Tolerance · Immunohistochemistry · Lactobacillus casei · Mice · Multiple Sclerosis · Myelin Basic Proteins · Peptide Fragments · Rabbits · Recombinant Fusion Proteins · Tetanus · Tetanus Toxin
[Abstract]

5 FcR interactions do not play a major role in inhibition of experimental autoimmune encephalomyelitis by anti-CD154 monoclonal antibodies
article 2004    
Author: Nagelkerken, L. · Haspels, I. · Rijs, W. van · Blauw, B. · Ferrant, J.L. · Hess, D.M. · Garber, E.A. · Taylor, F.R. · Burkly, L.C.
Keywords: CD40 ligand monoclonal antibody · allergic encephalomyelitis · allotransplantation · animal cell · animal experiment · animal model · cell infiltration · complement fixation · controlled study · fluorescence activated cell sorting · glycosylation · immunoreactivity · lymphocyte depletion · mouse · nonhuman · Th1 cell · Animals · Antibodies, Monoclonal · B-Lymphocytes · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Female · Glycosylation · Mice · Myelin Proteolipid Protein · Peptide Fragments · Receptors, Fc · T-Lymphocytes
[Abstract]

6 Tolerance controls encephalitogenicity of αB-crystallin in the Lewis rat
article 2000    
Author: Stipdonk, M.J.B. van · Willems, A.A. · Plomp, A.C. · Noort, J.M. van · Boog, C.J.P.
Keywords: Health · Tolerance · Autoantigen · Crystallin · Myelin · Myelin associated glycoprotein · Allergic encephalomyelitis · Animal cell · Animal experiment · Autoimmune disease · Central nervous system · Controlled study · Immunization · Lymphocyte proliferation · Multiple sclerosis · Nonhuman · Rat strain · T lymphocyte · Animals · Autoantigens · Cattle · Crystallins · Dose-Response Relationship, Immunologic · Encephalomyelitis, Autoimmune, Experimental · Hypersensitivity, Delayed · Immune Tolerance · Immunity, Cellular · Immunodominant Epitopes · Lymphoid Tissue · Male · Mice · Organ Specificity · Peptide Fragments · Phosphorylation · Rats · Rats, Inbred Lew · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Species Specificity · T-Lymphocytes
[Abstract]

7 T- and B-cell nonresponsiveness to self-αB-crystallin in SJL mice prevents the induction of experimental allergic encephalomyelitis
article 2000    
Author: Stipdonk, M.J.B. van · Willems, A.A. · Verbeek, R. · Boog, C.J.P. · Noort, J.M. van
Keywords: Health · Antigens · Rodents · Tolerance · Alpha crystallin · Beta crystallin · Peptide · Active immunization · Adoptive transfer · Allergic encephalomyelitis · Animal cell · Animal experiment · Animal model · Antibody response · Autoimmunity · Cell line · Cell proliferation · Cytokine production · Immunological tolerance · Immunopathogenesis · Lymphocyte function · Lymphoid organ · Nonhuman · Protein expression · Adoptive Transfer · Animals · Autoimmunity · B-Lymphocytes · Cattle · Crystallins · Encephalomyelitis, Autoimmune, Experimental · Female · H-2 Antigens · Immune Tolerance · Interferon Type II · Interleukin-4 · Lymphocytes · Lymphoid Tissue · Mice · Mice, Inbred Strains · Myelin Sheath · Nerve Tissue Proteins · Species Specificity · T-Lymphocytes · Vaccination
[Abstract]

8 1H-NMR spectroscopy combined with pattern recognition analysis reveals characteristic chemical patterns in urines of MS patients and non-human primates with MS-like disease
article 2003    
Author: Hart, B.A. 't · Vogels, J.T.W.E. · Spijksma, G. · Brok, H.P.M. · Polman, C. · Greef, J. van der
Keywords: Biology · Analytical research · Inflammatory demyelination · MS disease markers · NMR spectroscopy · Pattern recognition · Urine · myelin protein · organic compound · glycoprotein · tritium · animal model · article · autoimmune disease · chemical composition · clinical article · controlled study · disease course · encephalomyelitis · female · human · male · marmoset · molecular recognition · multiple sclerosis · multivariate analysis · nonhuman · primate · priority journal · proton nuclear magnetic resonance · urinalysis · validation process · allergic encephalomyelitis · animal · automated pattern recognition · chemistry · comparative study · disease model · immunization · immunology · methodology · nuclear magnetic resonance spectroscopy · species difference · time · urine · Animals · Callithrix · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Female · Glycoproteins · Humans · Immunization · Magnetic Resonance Spectroscopy · Male · Multiple Sclerosis · Multivariate Analysis · Myelin Proteins · Pattern Recognition, Automated · Species Specificity · Time Factors · Tritium · Urine
[Abstract]

9 Soluble mannosylated myelin peptide inhibits the encephalitogenicity of autoreactive T cells during experimental autoimmune encephalomyelitis
article 2007    
Author: Kel, J. · Oldenampsen, J. · Luca, M. · Drijfhout, J.W. · Koning, F. · Nagelkerken, L.
Keywords: Biology · Biomedical Research · gamma interferon · interleukin 23 · major histocompatibility antigen class 2 · myelin · proteolipid · autoantigen · epitope · lymphocyte antigen receptor · mannose · peptide fragment · proteolipid protein · proteolipid protein 139 151 · proteolipid protein 139-151 · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · female · histopathology · immunization · immunomodulation · immunoreactivity · incidence · macrophage · mouse · nonhuman · priority journal · solubility · spinal cord · T lymphocyte · animal · chemistry · drug effect · immunology · inflammation · lymphocyte activation · pathology · Animals · Autoantigens · Encephalomyelitis, Autoimmune, Experimental · Female · Immunodominant Epitopes · Inflammation · Lymphocyte Activation · Mannose · Mice · Myelin Proteolipid Protein · Peptide Fragments · Receptors, Antigen, T-Cell · Spinal Cord · T-Lymphocytes
[Abstract]

10 Non-invasive measurement of brain damage in a primate model of multiple sclerosis
article 2004    
Author: T Hart, B.A. · Vogels, J. · Bauer, J. · Brok, H.P.M. · Blezer, E.
Keywords: Biology Health · Analytical research · myelin · allergic encephalomyelitis · brain injury · chemometric analysis · demyelination · diagnostic imaging · human · immunopathology · marmoset · multiple sclerosis · neurologic disease · neuropathology · non invasive measurement · nonhuman · nuclear magnetic resonance imaging · nuclear magnetic resonance spectroscopy · pattern recognition · positron emission tomography · proton nuclear magnetic resonance · review · urinalysis · white matter · X ray analysis · Animals · Animals, Outbred Strains · Antigens, CD · Biological Markers · Brain · Callithrix · CD4-Positive T-Lymphocytes · Chronic Disease · Demyelinating Diseases · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Genes, MHC Class II · Humans · Magnetic Resonance Imaging · Magnetic Resonance Spectroscopy · Mice · Multiple Sclerosis · Myelin Basic Proteins · Myelin-Associated Glycoprotein · T-Lymphocytes, Cytotoxic · Th2 Cells · Animalia · Callithrix · Callithrix jacchus · marmosets · Primates · Rodentia
[Abstract]

11 Induction of EAE by T cells specific for alpha B-crystallin depends on prior viral infection in the CNS
article 2007    
Author: Verbeek, R. · Dongen, H. van · Wawrousek, E.F. · Amor, S. · Noort, J.M. van
Keywords: Biology · Biomedical Research · alpha crystallin · myelin · allergic encephalomyelitis · animal cell · animal experiment · animal model · antigen expression · article · brain infection · cell specificity · controlled study · encephalitis · immune response · immunological tolerance · lymphocyte transfer · mouse · multiple sclerosis · nonhuman · pathogenicity · priority journal · recipient · Semliki Forest alphavirus · T lymphocyte · T lymphocyte activation · virus infection · virus strain · virus virulence · Adoptive Transfer · alpha-Crystallin B Chain · Alphavirus Infections · Animals · Cells, Cultured · Central Nervous System Viral Diseases · Encephalomyelitis, Autoimmune, Experimental · Immune Tolerance · Inflammation Mediators · Lymphocyte Activation · Mice · Mice, Biozzi · Mice, Inbred C57BL · Mice, Knockout · Semliki forest virus · Spinal Cord · T-Lymphocytes · Time Factors
[Abstract]

12 Mannosylated self-peptide inhibits the development of experimental autoimmune encephalomyelitis via expansion of nonencephalitogenic T cells
article 2008    
Author: Kel, J.M. · Slütter, B. · Drijfhout, J.W. · Koning, F. · Nagelkerken, L.
Keywords: Biology · Biomedical Research · C-type lectins · Delayed-type hypersensitivity (DTH) · Tolerance · chemokine · cytokine · pertussis toxin · protein m plp139 151 · protein plp139 151 · proteolipid protein · adoptive transfer · allergic encephalomyelitis · animal cell · animal experiment · antigen specificity · article · autoimmunity · CD4+ T lymphocyte · clonogenesis · controlled study · cytokine production · delayed hypersensitivity · drug inhibition · drug tolerance · effector cell · female · immunization · immunocompetent cell · lymphocyte transformation · mouse · nonhuman · priority journal · T lymphocyte · transgenics · Animals · Cell Count · Cell Proliferation · Clone Cells · Encephalomyelitis, Autoimmune, Experimental · Epitopes · Female · Immune Tolerance · Immunization · Mannose · Mice · Peptides · Pertussis Toxin · Spleen · T-Lymphocytes · Mus
[Abstract]

13 Mannosylated PLP139-151 induces peptide-specific tolerance to experimental autoimmune encephalomyelitis
article 2005    
Author: Luca, M.E. · Kel, J.M. · Rijs, W. van · Drijfhout, J.W. · Koning, F. · Nagelkerken, L.
Keywords: C-type lectins · EAE · Mannose-receptor · Tolerance · immunoglobulin G2 · myelin proteolipid protein[139-151] · proteolipid protein · unclassified drug · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · cell migration · cell proliferation · controlled study · delayed hypersensitivity · drug effect · drug efficacy · female · immunization · mouse · nonhuman · priority journal · T lymphocyte · Amino Acid Sequence · Animals · Cell Movement · Cells, Cultured · Central Nervous System · Encephalomyelitis, Autoimmune, Experimental · Female · Hypersensitivity, Delayed · Immunodominant Epitopes · Injections, Subcutaneous · Leukocytes, Mononuclear · Mannose · Mice · Molecular Sequence Data · Myelin Proteolipid Protein · Peptide Fragments · Self Tolerance · Severity of Illness Index · Th1 Cells
[Abstract]

14 Protective and therapeutic role for αB-crystallin in autoimmune demyelination
article 2007    
Author: Ousman, S.S. · Tomooka, B.H. · Noort, J.M. van · Wawrousek, E.F. · O'Conner, K. · Hafler, D.A. · Sobel, R.A. · Robinson, W.H. · Steinman, L.
Keywords: Biomedical Research · caspase 3 · cytokine · gamma interferon · interleukin 12p40 · interleukin 17 · interleukin 2 · recombinant alphab crystallin · recombinant protein · tumor necrosis factor · antibody · brain · gene · immune response · immune system · nervous system disorder · rodent · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · apoptosis · article · astrocyte · central nervous system · cerebrospinal fluid · controlled study · cytokine release · demyelination · female · gene function · human · immune response · immune system · macrophage · mouse · multiple sclerosis · myelin sheath · nick end labeling · nonhuman · priority journal · T lymphocyte · Th1 cell · wild type · alpha-Crystallin B Chain · Animals · Apoptosis · Astrocytes · Caspase 3 · Encephalomyelitis, Autoimmune, Experimental · Humans · Inflammation · Macrophages · MAP Kinase Signaling System · Mice · Multiple Sclerosis · Myelin Sheath · Neuroglia · Neuroprotective Agents · NF-kappa B · T-Lymphocytes, Helper-Inducer · Mus
[Abstract]

15 Targeting the tetraspanin CD81 blocks monocyte transmigration and ameliorates EAE
article 2008    
Author: Dijkstra, S. · Kooij, G. · Verbeek, R. · Pol, S.M.A. van der · Amor, S. · Geisert Jr., E.E. · Dijkstra, C.D. · Noort, J.M. van · Vries, H.E.d.
Keywords: Biology · Biomedical Research · CD81 · EAE · Multiple sclerosis · Tetraspanins · Therapeutic antibodies · Transendothelial migration · CD81 antigen · monoclonal antibody · monoclonal antibody 1 3 3 22 · monoclonal antibody 1D6 · monoclonal antibody 2F7 · monoclonal antibody AMP1 · monoclonal antibody CD81 · monoclonal antibody Eat2 · monoclonal antibody JS81 · monoclonal antibody TA2 · tetraspanin · unclassified drug · very late activation antigen 4 antibody · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · antiinflammatory activity · article · controlled study · drug effect · endothelium cell · female · human · human cell · in vitro study · in vivo study · monocyte · monolayer culture · mouse · myelitis · neurologic disease · neutrophil chemotaxis · nonhuman · priority journal · protein targeting · rat · treatment outcome · Animals · Antibodies, Monoclonal · Antigens, CD · Blood-Brain Barrier · Cell Line, Transformed · Cerebral Arteries · Chemotaxis, Leukocyte · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Endothelial Cells · Female · Humans · Immunosuppression · Immunosuppressive Agents · Mice · Monocytes · Multiple Sclerosis · Rats · Treatment Outcome
[Abstract]

16 αB-Crystallin-reactive T cells from knockout mice are not encephalitogenic
article 2006    
Author: Wang, C. · Chou, Y.K. · Rich, C.M. · Link, J.M. · Afentoulis, M.E. · Noort, J.M. van · Wawrousek, E.F. · Offner, H. · Bark, A.A. van den
Keywords: EAE/MS · Knockout mice · T cells · Tolerance · Alpha B crystallin · Amino acid derivative · Crystallin · Cytokine · Encephalitogenic protein · Heat shock protein · Methionylglutamylvalylglycyltryptophyltyrosylarginylserylprolyl Phenylalanylserylarginylvalylvalylhistidylleucyltyrosylarginylasparaginylglycyl lysine · Unclassified drug · Alpha crystallin · Glycoprotein · Myelin oligodendrocyte glycoprotein (35 55) · Peptide fragment · Allergic encephalomyelitis · Animal cell · Animal experiment · Animal model · Animal tissue · CD4+ T lymphocyte · Cell line · Cell proliferation · Central nervous system · Controlled study · Cytokine release · Disease severity · Immunization · Immunocompetence · Immunological tolerance · Mouse · Multiple sclerosis · Nonhuman · Nucleotide sequence · Protein expression · Protein function · Th1 cell · Genetics · Lmmunology · Lymph node · Molecular genetics · Mouse mutant · Physiology · Reverse transcription polymerase chain reaction · Alpha-Crystallin B Chain · Amino Acid Sequence · Animals · Encephalomyelitis, Autoimmune, Experimental · Glycoproteins · Lymph Nodes · Lymphocyte Activation · Mice · Mice, Knockout · Molecular Sequence Data · Peptide Fragments · Reverse Transcriptase Polymerase Chain Reaction · Spleen · T-Lymphocytes
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date