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Showing 1 to 9 of 9 found. | Sort by date

1 Autoantibodies against alpha B-crystallin, a candidate autoantigen in multiple sclerosis, are part of a normal human immune repertoire
article 2006    
Author: Noort, J.M. van · Verbeek, R. · Meilof, J.F. · Polman, C.H. · Amor, S.
Keywords: Health · Biomedical Research · Alpha B-crystallin · Determinant spreading · Alpha crystallin · Autoantibody · Immunoglobulin A · Immunoglobulin G · Immunoglobulin M · Antigen antibody reaction · Cellular immunity · Clinical article · Controlled study · Disease association · Eye inflammation · Immune response · Immunoglobulin blood level · Immunoreactivity · T lymphocyte · Adult · alpha-Crystallin B Chain · Antibody Specificity · Autoantibodies · Autoantigens · Chromatography, High Pressure Liquid · Electrophoresis, Polyacrylamide Gel · Eye Proteins · Female · Humans · Immune System · Lens, Crystalline · Male · Middle Aged · Multiple Sclerosis · Uveitis
[Abstract]

2 Induction of EAE by T cells specific for alpha B-crystallin depends on prior viral infection in the CNS
article 2007    
Author: Verbeek, R. · Dongen, H. van · Wawrousek, E.F. · Amor, S. · Noort, J.M. van
Keywords: Biology · Biomedical Research · alpha crystallin · myelin · allergic encephalomyelitis · animal cell · animal experiment · animal model · antigen expression · article · brain infection · cell specificity · controlled study · encephalitis · immune response · immunological tolerance · lymphocyte transfer · mouse · multiple sclerosis · nonhuman · pathogenicity · priority journal · recipient · Semliki Forest alphavirus · T lymphocyte · T lymphocyte activation · virus infection · virus strain · virus virulence · Adoptive Transfer · alpha-Crystallin B Chain · Alphavirus Infections · Animals · Cells, Cultured · Central Nervous System Viral Diseases · Encephalomyelitis, Autoimmune, Experimental · Immune Tolerance · Inflammation Mediators · Lymphocyte Activation · Mice · Mice, Biozzi · Mice, Inbred C57BL · Mice, Knockout · Semliki forest virus · Spinal Cord · T-Lymphocytes · Time Factors
[Abstract]

3 Encephalitogenic and immunogenic potential of the stress protein αB-crystallin in Biozzi ABH (H-2A(g7)) mice
article 2000    
Author: Thoua, N.-M. · Noort, J.M. van · Baker, D. · Bose, A. · Sechel, A.C. van · Stipdonk, M.J.B. van · Travers, P.J. · Amor, S.
Keywords: Health · αB-Crystallin · Experimental allergic encephalomyelitis · Multiple sclerosis · Peptide epitopes, tolerance · Alpha crystallin · Antigen · Beta crystallin · Epitope · Myelin · Allergic encephalomyelitis · Animal cell · Animal experiment · Animal model · Animal tissue · Autoimmunity · Immunological tolerance · Lymphoid tissue · Multiple sclerosis · Nonhuman · Protein expression · T lymphocyte activation · Animals · Cattle · Crystallins · Encephalitis · Epitopes · Lymphoid Tissue · Mice · Mice, Mutant Strains · Models, Chemical · Molecular Conformation · Peptide Mapping · T-Lymphocytes
[Abstract]

4 αB-Crystallin-reactive T cells from knockout mice are not encephalitogenic
article 2006    
Author: Wang, C. · Chou, Y.K. · Rich, C.M. · Link, J.M. · Afentoulis, M.E. · Noort, J.M. van · Wawrousek, E.F. · Offner, H. · Bark, A.A. van den
Keywords: EAE/MS · Knockout mice · T cells · Tolerance · Alpha B crystallin · Amino acid derivative · Crystallin · Cytokine · Encephalitogenic protein · Heat shock protein · Methionylglutamylvalylglycyltryptophyltyrosylarginylserylprolyl Phenylalanylserylarginylvalylvalylhistidylleucyltyrosylarginylasparaginylglycyl lysine · Unclassified drug · Alpha crystallin · Glycoprotein · Myelin oligodendrocyte glycoprotein (35 55) · Peptide fragment · Allergic encephalomyelitis · Animal cell · Animal experiment · Animal model · Animal tissue · CD4+ T lymphocyte · Cell line · Cell proliferation · Central nervous system · Controlled study · Cytokine release · Disease severity · Immunization · Immunocompetence · Immunological tolerance · Mouse · Multiple sclerosis · Nonhuman · Nucleotide sequence · Protein expression · Protein function · Th1 cell · Genetics · Lmmunology · Lymph node · Molecular genetics · Mouse mutant · Physiology · Reverse transcription polymerase chain reaction · Alpha-Crystallin B Chain · Amino Acid Sequence · Animals · Encephalomyelitis, Autoimmune, Experimental · Glycoproteins · Lymph Nodes · Lymphocyte Activation · Mice · Mice, Knockout · Molecular Sequence Data · Peptide Fragments · Reverse Transcriptase Polymerase Chain Reaction · Spleen · T-Lymphocytes
[Abstract]

5 Tolerization of an established αb-crystallin-reactive T-cell response by intravenous antigen
article 2007    
Author: Verbeek, R. · Mark, K. van der · Wawrousek, E.F. · Plomp, A.C. · Noort, J.M. van
Keywords: Biology · Biomedical Research · αB-crystallin · Autoimmunity · Multiple sclerosis · T cells · Tolerance · alpha crystallin · alphab crystallin · antibody · autoantigen · Freund adjuvant · ovalbumin · epitope · gamma interferon · immunoglobulin G · recombinant protein · animal cell · animal experiment · antibody blood level · antibody response · antigen specificity · article · cellular immunity · controlled study · delayed hypersensitivity · dose response · drug dose comparison · drug efficacy · immune response · immunization · immunological tolerance · immunoregulation · mouse · multiple sclerosis · nonhuman · priority journal · protein deficiency · T lymphocyte activation · animal · biosynthesis · cell culture · dendritic cell · immunology · intravenous drug administration · lymphocyte activation · T lymphocyte subpopulation · time · alpha-Crystallin B Chain · Animals · Autoantigens · Cells, Cultured · Dendritic Cells · Dose-Response Relationship, Immunologic · Epitopes · Hypersensitivity, Delayed · Immune Tolerance · Immunoglobulin G · Injections, Intravenous · Interferon Type II · Lymphocyte Activation · Mice · Multiple Sclerosis · Recombinant Proteins · T-Lymphocyte Subsets · Time Factors
[Abstract]

6 Presentation of αB-crystallin to T cells in active multiple sclerosis lesions: An early event following inflammatory demyelination
article 2000    
Author: Bajramović, J.J. · Plomp, A.C. · Goes, A. van der · Koevoets, C. · Newcombe, J. · Cuzner, M.L. · Noort, J.M. van
Keywords: Health · Alpha crystallin · B7 antigen · Beta crystallin · CD40 antigen · Cytokine · Gamma interferon · Major histocompatibility antigen class 2 · Myelin basic protein · Adult · Blood brain barrier · Clinical article · Controlled stud · Demyelination · Human tissue · Immunohistochemistry · Inflammation · Macrophage function · Multiple sclerosis · Neurologic disease · Antigen Presentation · Antigens, CD40 · Antigens, CD80 · Autoantigens · Cathepsins · Cell Movement · Crystallins · Demyelinating Diseases · Histocompatibility Antigens Class II · Humans · Hydrolysis · Inflammation · Macrophages · Multiple Sclerosis · Myelin Proteins · Myelin Sheath · Phagocytosis · T-Lymphocytes
[Abstract]

7 T- and B-cell nonresponsiveness to self-αB-crystallin in SJL mice prevents the induction of experimental allergic encephalomyelitis
article 2000    
Author: Stipdonk, M.J.B. van · Willems, A.A. · Verbeek, R. · Boog, C.J.P. · Noort, J.M. van
Keywords: Health · Antigens · Rodents · Tolerance · Alpha crystallin · Beta crystallin · Peptide · Active immunization · Adoptive transfer · Allergic encephalomyelitis · Animal cell · Animal experiment · Animal model · Antibody response · Autoimmunity · Cell line · Cell proliferation · Cytokine production · Immunological tolerance · Immunopathogenesis · Lymphocyte function · Lymphoid organ · Nonhuman · Protein expression · Adoptive Transfer · Animals · Autoimmunity · B-Lymphocytes · Cattle · Crystallins · Encephalomyelitis, Autoimmune, Experimental · Female · H-2 Antigens · Immune Tolerance · Interferon Type II · Interleukin-4 · Lymphocytes · Lymphoid Tissue · Mice · Mice, Inbred Strains · Myelin Sheath · Nerve Tissue Proteins · Species Specificity · T-Lymphocytes · Vaccination
[Abstract]

8 αB-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions
article 2010    
Author: Noort, J.M. van · Bsibsi, M. · Gerritsen, W.H. · Valk, P. van der · Bajramovic, J.J. · Steinman, L. · Amor, S.
Keywords: Biology · Biomedical Research · αB-crystallin · Autoantibodies · Microglia · Multiple sclerosis · Preactive lesions · alpha B crystallin · antibody · CCL1 chemokine · chemokine · crystallin · HLA DR antigen · immunoglobulin G · interleukin 10 · interleukin 13 · interleukin 17 · myelin protein · transforming growth factor beta · tumor necrosis factor · unclassified drug · alpha crystallin · basic helix loop helix transcription factor · cytokine · glial fibrillary acidic protein · nerve protein · neurofilament protein · neurofilament protein L · OLIG2 protein, human · proteolipid protein · adaptive immunity · adult · antibody blood level · article · cell activation · clinical article · controlled study · human · immunoglobulin blood level · innate immunity · male · microglia · multiple sclerosis · priority journal · protein secretion · white matter · immunology · mass spectrometry · metabolism · methodology · middle aged · oligodendroglia · pathology · pathophysiology · physiology · Adaptive Immunity · Adult · alpha-Crystallins · Basic Helix-Loop-Helix Transcription Factors · Cytokines · Glial Fibrillary Acidic Protein · HLA-DR Antigens · Humans · Mass Spectrometry · Microglia · Middle Aged · Multiple Sclerosis · Myelin Proteolipid Protein · Nerve Tissue Proteins · Neurofilament Proteins · Oligodendroglia
[Abstract]

9 Protective and therapeutic role for αB-crystallin in autoimmune demyelination
article 2007    
Author: Ousman, S.S. · Tomooka, B.H. · Noort, J.M. van · Wawrousek, E.F. · O'Conner, K. · Hafler, D.A. · Sobel, R.A. · Robinson, W.H. · Steinman, L.
Keywords: Biomedical Research · caspase 3 · cytokine · gamma interferon · interleukin 12p40 · interleukin 17 · interleukin 2 · recombinant alphab crystallin · recombinant protein · tumor necrosis factor · antibody · brain · gene · immune response · immune system · nervous system disorder · rodent · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · apoptosis · article · astrocyte · central nervous system · cerebrospinal fluid · controlled study · cytokine release · demyelination · female · gene function · human · immune response · immune system · macrophage · mouse · multiple sclerosis · myelin sheath · nick end labeling · nonhuman · priority journal · T lymphocyte · Th1 cell · wild type · alpha-Crystallin B Chain · Animals · Apoptosis · Astrocytes · Caspase 3 · Encephalomyelitis, Autoimmune, Experimental · Humans · Inflammation · Macrophages · MAP Kinase Signaling System · Mice · Multiple Sclerosis · Myelin Sheath · Neuroglia · Neuroprotective Agents · NF-kappa B · T-Lymphocytes, Helper-Inducer · Mus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 9 of 9 found. | Sort by date