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1 Apolipoproteine E en familiale dysbetalipoproteinemie
article 1989    
Author: Havekes, L.M.
Keywords: Apolipoproteins · Lipoproteinemia
[Abstract]

2 Suppression of cholesterol synthesis in cultured fibroblasts from a patient with homozygous familial hypercholesterolemia by her own low density lipoprotein density fraction. A possible role of apolipoprotein E
article 1980    
Author: Havekes, L. · Vermeer, B.J. · Wit, E. de
Keywords: Biology · Apolipoproteins · Apolipoproteins E · Cells, Cultured · Cholesterol · Female · Fibroblasts · Homozygote · Human · Hypercholesterolemia, Familial · Lipoproteins, LDL · Phospholipids
[Abstract]

3 Apolipoprotein A-IV polymorhism and its effect on plasma lipid and apolipoprotein concentrations
article 1988    
Author: Knijff, P. de · Rosseneu, M. · Beisiegel, U. · Keersgieter, W. de · Frants, R.R. · Havekes, L.M.
Keywords: Biology · Triacylglycerol · Apolipoprotein blood level · Heredity · Lipid blood level · Population genetics · Protein polymorphism · Blood · Genetic polymorphism · Genetics · Phenotype · Adult · Alleles · Animal · Apolipoproteins · Apolipoproteins A · Apolipoproteins B · Cholesterol · Gene Frequency · Human · Lipids · Male · Phenotype · Polymorphism (Genetics) · Rabbits · Triglycerides
[PDF] [Abstract]

4 Use of transgenic mice in lipoprotein metabolism and atherosclerosis research
article 1997    
Author: Havekes, L.M. · Vlijmen, B.J.M. van · Jong, M.C. · Dijk, K.W. van · Hofker, M.H.
Keywords: Biology · Age Factors · Animals · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Female · Humans · Lipids · Lipoproteins · Lipoproteins, VLDL · Male · Mice · Mice, Transgenic · Sex Factors · Animalia · Mus musculus
[Abstract]

5 Role of apoCs in lipoprotein metabolism : Functional differences between ApoC1, ApoC2, and ApoC3
article 1999    
Author: Jong, M.C. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Apolipoproteins · Lipoprotein lipase · Lipoproteins, VLDL · Mice, transgenic · Animals · Apolipoprotein C-I · Apolipoprotein C-II · Apolipoprotein C-III · Apolipoproteins C · Humans · Lipoproteins · Mice · Mice, Transgenic · Mutation
[Abstract]

6 Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion
article 2001    
Author: Mensenkamp, A.R. · Teusink, B. · Baller, J.F.W. · Wolters, H. · Havinga, R. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Fatty Liver · Lipid Metabolism · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · RNA, Messenger · Triglycerides
[Abstract]

7 Insulin suppresses apolipoprotein(a) synthesis by primary cultures of cynomolgus monkey hepatocytes
article 1999    
Author: Neele, D.M. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · Apolipoprotein(a) · Cynomolgus monkey hepatocytes · Insulin · Animals · Apolipoprotein B-100 · Apolipoproteins · Apolipoproteins B · Apoprotein(a) · Cells, Cultured · Female · Gene Expression Regulation · Insulin · Lipoprotein(a) · Liver · Macaca fascicularis · Male · RNA, Messenger · Transcription, Genetic
[Abstract]

8 Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
article 2001    
Author: Jong, M.C. · Rensen, P.C.N. · Dahlmans, V.E.H. · Boom, H. van der · Berkel, T.J.C. van · Havekes, L.M.
Keywords: Animals · Apolipoprotein C-III · Apolipoproteins C · Apolipoproteins E · Chylomicrons · Crosses, Genetic · Female · Gene Deletion · Hydrolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Time Factors · Triglycerides
[PDF] [Abstract]

9 Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis
article 2000    
Author: Rensen, P.C.N. · Jong, M.C. · Vark, L.C. van · Boom, H. van der · Hendriks, W.L. · Berkel, T.J.C. van · Biessen, E.A.L. · Havekes, L.M.
Keywords: Animals · Apolipoproteins B · Apolipoproteins E · Biological Transport · Blood · Cells, Cultured · Cholesterol Esters · Emulsions · Endocytosis · Lipoproteins · Lipoproteins, LDL · Lipoproteins, VLDL · Liver · Lysosomes · Male · Mice · Mice, Inbred C57BL · Protein Processing, Post-Translational · Animalia
[PDF] [Abstract]

10 Severe learning deficits in apolipoprotein E-knockout mice in a water maze task
article 1997    
Author: Oitzl, M.S. · Mulder, M. · Lucassen, P.J. · Havekes, L.M. · Grootendorst, J. · Kloet, E.R. de
Keywords: Alzheimer' s disease · Animals · Apolipoproteins E · Learning Disorders · Male · Maze Learning · Mice · Mice, Knockout · Motor Activity · Reference Values · Swimming
[Abstract]

11 Effects of fenofibrate on hyperlipidemia and postprandial triglyceride metabolism in human apolipoprotein C1 transgenic mice
article 1998    
Author: Jong, M.C. · Dahlmans, V.E.H. · Princen, H.M.G. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Apo C · LDL-receptor · Transgenic mice · Triglycerides · Animals · Antilipemic Agents · Apolipoproteins C · Humans · Hyperlipidemias · Mice · Mice, Transgenic · Procetofen · Triglycerides
[Abstract]

12 Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis
article 1998    
Author: Hofker, M.H. · Vlijmen, B.J.M. van · Havekes, L.M.
Keywords: Health · APOE · Apolipoprotein · Cholesterol · Gene targeting · Lipoprotein · Triglyceride · Animals · Apolipoproteins E · Arteriosclerosis · Disease Models, Animal · Humans · Hyperlipidemias · Mice · Mice, Transgenic
[Abstract]

13 Immunoelectronmicroscopy of the binding of high density lipoprotein apoproteins to normal and hypercholesterolemic human fibroblasts
article 1981    
Author: Emeis, J.J. · Vermeer, B.J. · Havekes, L.
Keywords: Biology · Apolipoprotein A-I · Apolipoproteins · Cell Membrane · Cells, Cultured · Fibroblasts · Human · Hypercholesterolemia, Familial · Immunologic Techniques · Lipoproteins, HDL · Microscopy, Electron
[Abstract]

14 Stimulation of the in Vivo Production of Very Low Density Lipoproteins by Apolipoprotein E Is Independent of the Presence of the Low Density Lipoprotein Receptor
article 2001    
Author: Teusink, B. · Mensenkamp, A.R. · Boom, H. van der · Kuipers, F. · Dijk, K.W. van · Havekes, L.M.
Keywords: Animalia · Gillia · Animals · Apolipoproteins E · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Receptors, LDL
[PDF] [Abstract]

15 Severe hyperlipidemia in apolipoprotein E2 homozygotes due to a combined effect of hyperinsulinemia and an SstI polymorphism
article 1999    
Author: Sijbrands, E.J.G. · Hoffer, M.J.V. · Meinders, A.E. · Havekes, L.M. · Frants, R.R. · Smelt, A.H.M. · Knijff, P. de
Keywords: Apolipoprotein E · Hyperinsulinemia · Hyperlipoproteinemia type III · Xanthomas · Adult · Aged · Aged, 80 and over · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoprotein E2 · Apolipoproteins A · Apolipoproteins C · Apolipoproteins E · Cholesterol, HDL · Cholesterol, LDL · Cholesterol, VLDL · Family Health · Female · Gene Expression · Haplotypes · Homozygote · Humans · Hyperinsulinism · Hyperlipidemias · Male · Middle Aged · Pedigree · Polymorphism, Single Nucleotide · Promoter Regions (Genetics) · Xanthomatosis
[Abstract]

16 Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine
article 1996    
Author: Hasler-Rapacz, J. · Kempen, H.J. · Princen, H.M.G. · Kudchodkar, B.J. · Lacko, A. · Rapacz, J.
Keywords: Biology · animal model · apolipoproteins · familial hypercholesterolemia · simvastatin · swine · apolipoprotein a · apolipoprotein b · apolipoprotein c3 · apolipoprotein e · high density lipoprotein cholesterol · hydroxymethylglutaryl coenzyme a reductase · lathosterol · lipid · low density lipoprotein cholesterol · phosphatidylcholine sterol acyltransferase · simvastatin · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · animal tissue · article · calculation · cholesterol blood level · dose response · enzyme activity · hypercholesterolemia · hyperlipidemia · lipid analysis · lipid blood level · lipoprotein blood level · nonhuman · priority journal · statistical analysis · swine · Animals · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoproteins · Apolipoproteins B · Apolipoproteins C · Apolipoproteins E · Cholesterol · Cholesterol, HDL · Cholesterol, LDL · Enzyme Inhibitors · Female · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipoproteinemia Type II · Lipids · Male · Swine · Swine Diseases · Triglycerides
[Abstract]

17 Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
article 2005    
Author: Berbée, J.F.P. · Hoogt, C.C. van der · Sundararaman, D. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Apolipoprotein C-I · Fatty acids · Lipid metabolism · Lipoprotein lipase · Triglycerides · Very low density lipoprotein · Lipoprotein receptor · Tritium · Very low density lipoprotein · Animal experiment · Animal model · Cholesterol blood level · Controlled study · Enzyme activity · Half life time · Hyperlipidemia · Hyperlipoproteinemia type 3 · Lipolysis · Mouse · Nonhuman · Pathophysiology · Protein expression · Transgenic mouse · Animals · Apolipoproteins · Apolipoproteins C · Apolipoproteins E · Humans · Hypertriglyceridemia · Lactoferrin · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phenotype · Time Factors
[PDF] [Abstract]

18 Plasma levels of apolipoprotein E and cognitive function in old age
bookPart 2007    
Author: Mooijaart, S.P. · Vliet, P. van · Heemst, D. van · Rensen, P.C.N. · Berbée, J.F.P. · Jolles, J. · Craen, A.J.M. de · Westendorp, R.G.J.
Keywords: Biology · Biomedical Research · Dementia · Aged · Aged, 80 and over · Aging · Apolipoproteins E · Cardiovascular Diseases · Cerebrovascular Disorders · Cholesterol · Cognition Disorders · Dementia · Female · Genotype · Humans · Male · Neuropsychological Tests · Risk Factors
[Abstract]

19 Trans-intestinal cholesterol effl ux is not mediated through high density lipoprotein
article 2012    
Author: Vrins, C.L. · Ottenhoff, R. · Oever, K. van den · Waart, D.R. de · Kruyt, J.K. · Zhao, Y. · Berkel, T.J. van · Havekes, L.M. · Aerts, J.M. · Eck, M. van · Rensen, P.C. · Groen, A.K.
Keywords: Nutrition · Intestine · Apolipoproteins · Reverse cholesterol transport · Neutral sterols · Bile · Food and Nutrition · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

20 Atherosclerosis in APOE(*)3-Leiden transgenic mice from proliferative to atheromatous stage
article 1999    
Author: Lutgens, E. · Daemen, M. · Kockx, M. · Doevendans, P. · Hofker, M. · Havekes, L. · Wellens, H. · Muinck, E.D. de
Keywords: Biology · Apoptosis · Atherosclerosis · Genetics · Animals · Apolipoprotein E3 · Apolipoproteins E · Apoptosis · Arteriosclerosis · Diet, Atherogenic · Disease Models, Animal · Disease Progression · DNA · Female · Foam Cells · Male · Mice · Mice, Transgenic · Phenotype
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 124 found. Next | Sort by date