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1 Ageing and osteoarthritis: A different perspective
article 2003    
Author: Verzijl, N. · Bank, R.A. · TeKoppele, J.M. · Groot, J. de
Keywords: Biology Health · Biomedical Research · Advanced glycation end products · Cartilage · Chondrocyte · Collagen · Osteoarthritis · Articular cartilage · Cartilage degeneration · Cartilage matrix · Diabetes mellitus · Economic aspect · Musculoskeletal disease · Rigidity · Aging · Cartilage, Articular · Glycosylation End Products, Advanced · Humans
[Abstract]

2 Influence of site and age on biochemical characteristics of the collagen network of equine articular cartilage
article 1999    
Author: Brama, P.A.J. · TeKoppele, J.M. · Bank, R.A. · Weeren, P.R. van · Barneveld, A.
Keywords: Biology · Biomedical Research · collagen · aging · animal · animal disease · article · articular cartilage · histology · horse · horse disease · metabolism · osteochondritis · pathology · protein processing · Aging · Animals · Cartilage, Articular · Collagen · Horse Diseases · Horses · Osteochondritis · Protein Processing, Post-Translational
[Abstract]

3 Mechanical properties of the collagen network in human articular cartilage as measured by osmotic stress technique
article 1998    
Author: Basser, P.J. · Schneiderman, R. · Bank, R.A. · Wachtel, E. · Maroudas, A.
Keywords: Health · Collagen network · Connective tissue · Degeneration · Human cartilage · Hydration · Swelling · Tension · Collagen · Articular cartilage · Biomechanics · Calculation · Human · Human tissue · Hydration · Osmotic stress · Priority journal · Tensile strength · Cartilage, Articular · Collagen · Extracellular Matrix · Humans · Osmotic Pressure · Osteoarthritis · Polyethylene Glycols · Proteoglycans · Trypsin · Water
[Abstract]

4 Quantitative in vivo CT arthrography of the human osteoarthritic knee to estimate cartilage sulphated glycosaminoglycan content: correlation with ex-vivo reference standards
article 2016    
Author: Tiel, J. van · Siebelt, M. · Reijman, M. · Bos, P.K. · Waarsing, J.H. · Zuurmond, A.M. · Nasserinejad, K. · Osch, G.J.V.M. van · Verhaar, J.A.N. · Krestin, G.P. · Weinans, H. · Oei, E.H.G.
Keywords: Biology · CT arthrography · Sulphated glycosaminoglycan content · Knee osteoarthritis · Articular cartilage · Clinical research · Translational study · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

5 Compositional and metabolic changes in damaged cartilage are peak- stress, stress-rate, and loading-duration dependent
article 1999    
Author: Chen, C.-T. · Burton-Wurster, N. · Lust, G. · Bank, R.A. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · Biosynthesis · Compression testing · Impact testing · Metabolism · Monoclonal antibodies · Stress analysis · Tissue culture · Articular cartilage · Monoclonal antibody · Proteoglycan · Animal tissue · Articular cartilage · Cartilage degeneration · Cartilage matrix · Collagen degradation · Compression · Controlled study · Explant · Nonhuman · Proteoglycan synthesis · Shear stress · Tissue metabolism · Water content · Weight bearing · Animal · Cartilage · Collagen · Dogs · Fibronectins · Glycosaminoglycans · Immunohistochemistry · Osteoarthritis · Stress, Mechanical · Support, U.S. Gov't, P.H.S. · Time Factors · Water
[Abstract]

6 Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: The use of pentosidine levels as a quantitative measure of protein turnover
article 2001    
Author: Verzijl, N. · Groot, J. de · Bank, R.A. · Bayliss, M.T. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · Maroudas, A. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · Articular cartilage · Osteoarthritis · Pentosidine · Turnover · Aspartic acid · Collagen · Hyaluronic acid · Protein · Binding site · Controlled study · Glycation · Half life time · Human tissue · Protein domain · Protein metabolism · School child · Adolescent · Adult · Aged · Aged, 80 and over · Aggrecans · Aging · Arginine · Cartilage, Articular · Chemical Fractionation · Child · Extracellular Matrix Proteins · Glycosylation End Products, Advanced · Humans · Lectins, C-Type · Lysine · Middle Aged · Osteoarthritis · Proteochondroitin Sulfates · Proteoglycans
[Abstract]

7 Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: A possible mechanism through which age is a risk factor for osteoarthritis
article 2002    
Author: Verzijl, N. · Groot, J. de · Zaken, C.B. · Braun-Benjamin, O. · Maroudas, A. · Bank, R.A. · Mizrahi, J. · Schalkwijk, C.G. · Thorpe, S.R. · Baynes, J.W. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · 6 n carboxymethyllysine · Advanced glycation end product · Arginine · Collagen · Collagenase · Hydroxylysine · Pentosidine · Adult · Aging · Articular cartilage · Controlled study · Human · Human tissue · Hydration · Joint stiffness · Osmotic stress · Osteoarthritis · Priority journal · Protein cross linking · Protein glycosylation · Adult · Aging · Arginine · Cartilage, Articular · Collagen · Cross-Linking Reagents · Glycosylation End Products, Advanced · Humans · Lysine · Osteoarthritis · Pyruvaldehyde · Regression Analysis · Ribose · Stress, Mechanical · Tetroses
[Abstract]

8 Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma
article 2015    
Author: He, M. · Wijk, E. van · Berger, R. · Wang, M. · Strassburg, K. · Schoeman, J.C. · Vreeken, R.J. · Wietmarschen, H. van · Harms, A.C. · Kobayashi, M. · Hankemeier, T. · Greef, J. van der
Keywords: Biology · Collagen type 2 · Lipopolysaccharide · Oxylipin · Animal experiment · Animal model · Arthritis · Articular cartilage · Controlled study · Electrospray mass spectrometry · High performance liquid chromatography · Male · Mouse · Nonhuman · Oxidative stress · Tandem mass spectrometry · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

9 Age-related decrease in proteoglycan synthesis of human articular chondrocytes: The role of nonenzymatic glycation
article 1999    
Author: Groot, J. de · Verzijl, N. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · age · article · articular cartilage · cartilage cell · glycation · human · human tissue · pathogenesis · priority journal · proteoglycan synthesis · rheumatic disease · Adult · Aged · Aged, 80 and over · Aging · Arginine · Cartilage, Articular · Cross-Linking Reagents · Extracellular Matrix · Glycosylation End Products, Advanced · Humans · Lysine · Middle Aged · Osteoarthritis · Proteoglycans · Ribose
[Abstract]

10 Skin and urine pentosidine weakly correlate with joint damage in a cohort of patients with early signs of osteoarthritis (CHECK)
article 2010    
Author: Vos, P.A.J.M. · Groot, J. de · Huisman, A.M. · Oostveen, J.C.M. · Marijnissen, A.C.A. · Bijlsma, J.W.J. · El, B. van · Zuurmond, A.M. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Age · Canine · Cohort · Osteoarthritis · Pentosidine · pentosidine · adult · aged · article · articular cartilage · autopsy · cohort analysis · controlled study · creatinine clearance · disease severity · female · high performance liquid chromatography · hip · hip osteoarthritis · human · joint injury · knee · knee osteoarthritis · major clinical study · male · multiple regression · predictor variable · priority journal · radiography · skin · urinalysis · X ray
[Abstract]

11 Degeneration, inflammation, regeneration, and pain/disability in dogs following destabilization or articular cartilage grooving of the stifle joint
article 2008    
Author: Frost-Christensen, L.N. · Mastbergen, S.C. · Vianen, M.E. · Hartog, A. · Groot, J. de · Voorhout, G. · Wees, A.M.C. van · Lafeber, F.P.J.G. · Hazewinkel, H.A.W.
Keywords: Health · ACLT · Gait · Groove-model · Meniscectomy · Osteoarthritis · Animal experiment · Animal model · Animal tissue · Anterior cruciate ligament injury · Article · Articular cartilage · Cartilage cell · Controlled study · Disease model · Dog · Gait · Joint degeneration · Knee osteoarthritis · Knee pain · Knee radiography · Nonhuman · Osteophyte · Physical disability · Priority journal · Synovitis · Tissue regeneration · Animals · Anterior Cruciate Ligament · Arthralgia · Cartilage, Articular · Chondrocytes · Dogs · Gait · Inflammation · Joint Instability · Models, Animal · Osteoarthritis · Osteophyte · Regeneration · Stifle
[Abstract]

12 Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage
article 2002    
Author: Chen, A.C. · Temple, M.M. · Ng, D.M. · Verzijl, N. · Groot, J. de · TeKoppele, J.M. · Sah, R.L.
Keywords: Biology · Biomedical Research · advanced glycation end product · buffer · pentosidine · ribose · age · aging · animal tissue · article · articular cartilage · biomechanics · cattle · controlled study · culture medium · fluorescence · joint degeneration · joint fracture · light absorption · nonhuman · priority journal · rigidity · stress · tensile strength · Animals · Biomechanics · Cartilage, Articular · Cattle · Elasticity · Glycosylation End Products, Advanced · Ribose · Tensile Strength
[PDF] [Abstract]

13 Doxycycline inhibits collagen synthesis by differentiated articular chondrocytes.
article 1998    
Author: TeKoppele, J.M. · Beekman, B. · Verzijl, N. · Koopman, J.L. · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · antiinfective agent · collagen · doxycycline · metalloproteinase · protein synthesis inhibitor · proteinase inhibitor · animal · article · articular cartilage · biosynthesis · cartilage cell · cattle · cell culture · cytology · dog · drug antagonism · metabolism · osteoarthritis · Animals · Anti-Bacterial Agents · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Dogs · Doxycycline · Metalloendopeptidases · Osteoarthritis · Protease Inhibitors · Protein Synthesis Inhibitors
[Abstract]

14 Urinary CTX-II levels are associated with radiographic subtypes of osteoarthritis in hip, knee, hand, and facet joints in subject with familial osteoarthritis at multiple sites: The GARP study
article 2006    
Author: Meulenbelt, I. · Kloppenburg, M. · Kroon, H.M. · Houwing-Duistermaat, J.J. · Garnero, P. · Hellio Le Graverand, M.P. · Groot, J. de · Slagboom, P.E.
Keywords: Biology · Biomedical Research · carboxy terminal telopeptide · collagen type 2 · creatine · articular cartilage · controlled study · familial disease · hand · hip · intervertebral disk degeneration · knee · major clinical study · radiography · risk factor · sibling · urinalysis · Adult · Aged · Arthrography · Biological Markers · Collagen · Collagen Type I · Female · Hand Joints · Humans · Male · Middle Aged · Osteoarthritis · Osteoarthritis, Hip · Osteoarthritis, Knee · Peptides · Risk Assessment · Severity of Illness Index · Zygapophyseal Joint
[Abstract]

15 Degenerated human articular cartilage at autopsy represents preclinical osteoarthritic cartilage : comparison with clinically defined osteoarthritic cartilage
article 1997    
Author: Valburg, A.A. van · Wenting, M.J.G. · Beekman, B. · TeKoppele, J.M. · Lafeber, F.P.G.J. · Bijlsma, J.W.J.
Keywords: Health · Biomedical Research · cartilage · metalloproteinases · osteoarthritis · proteoglycans · metalloproteinase · proteoglycan · adult · aged · article · articular cartilage · autopsy · cartilage degeneration · controlled study · female · histochemistry · histology · human · human tissue · male · osteoarthritis · priority journal · Aged · Aged, 80 and over · Cartilage, Articular · Female · Humans · Knee Joint · Male · Metalloendopeptidases · Middle Aged · Osteoarthritis · Proteoglycans · Synovial Fluid · Synovial Membrane

16 Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes
article 2001    
Author: Groot, J. de · Verzijl, N. · Budde, M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Advanced glycation end product · Alginate culture · Cartilage · Chondrocyte · Collagen · Matrix metalloproteinase · Turnover · advanced glycation end product · alginic acid · collagen · matrix metalloproteinase · ribose · animal cell · article · articular cartilage · cartilage cell · cattle · cell culture · collagen defect · collagen degradation · collagen synthesis · controlled study · culture medium · enzyme activity · extracellular matrix · nonhuman · osteoarthritis · priority journal · reaction time · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Enzyme Precursors · Extracellular Matrix · Glycosylation End Products, Advanced · Matrix Metalloproteinases · Osteoarthritis · Ribose · Bovinae
[Abstract]

17 Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: The role of advanced glycation end products
article 2001    
Author: Groot, J. de · Verzijl, N. · Wenting-Van Wijk, M.J.G. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · glycosaminoglycan · matrix metalloproteinase · pentosidine · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · colorimetry · controlled study · disease course · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · protein degradation · rheumatoid arthritis · synovial fluid · Adult · Aged · Aged, 80 and over · Aging · Animals · Arginine · Arthritis, Rheumatoid · Cartilage, Articular · Cattle · Chromatography, High Pressure Liquid · Glycosaminoglycans · Humans · Knee Joint · Lysine · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Phenylmercuric Acetate · Ribose · Synovial Fluid
[Abstract]

18 Development of biochemical heterogeneity of articular cartilage: Influences of age and exercise
article 2002    
Author: Brama, P.A.J. · Tekoppele, J.M. · Bank, R.A. · Barneveld, A. · Weeren, P.R. van
Keywords: Health Biology · Biomedical Research · Age · Biochemical heterogeneity · Cartilage · Development · Exercise · Horse · Collagen · DNA · Glycosaminoglycan · Hydroxylysine · Hydroxyproline · Adaptation · Animal experiment · Articular cartilage · Biochemistry · Cell heterogeneity · Controlled study · Exercise · Horse · Nonhuman · Puerperium · Age · Aging · Animal · Animal disease · Chemistry · High performance liquid chromatography · Joint · Methodology · Newborn · Physiology · Animalia · Equidae · Equus caballus · Adaptation, Physiological · Age Factors · Aging · Animals · Animals, Newborn · Cartilage, Articular · Chromatography, High Pressure Liquid · Collagen · DNA · Glycosaminoglycans · Horses · Hydroxylysine · Hydroxyproline · Joints · Physical Conditioning, Animal
[Abstract]

19 Putative role of lysyl hydroxylation and pyridinoline cross-linking during adolescence in the occurrence of osteoarthritis at old age
article 2002    
Author: Bank, R.A. · Verzijl, N. · Lafeber, F.P.J.G. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · Collagen · Fatigue · Hydroxylysine · Osteoarthritis · Pyridinoline · collagen · hydroxylysine · pentosidine · pyridinoline · adolescence · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · collagen synthesis · controlled study · cross linking · fatigue · femur condyle · human · human tissue · hydroxylation · knee osteoarthritis · onset age · pathogenesis · priority journal · senescence · stress · stress strain relationship · Aged · Aged, 80 and over · Amino Acids · Arginine · Case-Control Studies · Collagen · Cross-Linking Reagents · Humans · Hydroxylysine · Lysine · Middle Aged · Osteoarthritis, Knee
[Abstract]

20 Topographical mapping of biochemical properties of articular cartilage in the equine fetlock joint
article 2000    
Author: Brama, P.A.J. · Tekoppele, J.M. · Bank, R.A. · Karssenberg, D. · Barneveld, A. · Weeren, P.R. van
Keywords: Biology · Biomedical Research · Biochemical · Cartilage · Horse · Mapping · Site · 1,9 dimethylmethylene blue · 1,9-dimethylmethylene blue · amino acid · bisbenzimide · collagen · DNA · drug derivative · fluorescent dye · glycosaminoglycan · hydroxylysine · methylene blue · pyridinoline · water · animal · animal disease · article · articular cartilage · biomechanics · biopsy · chemistry · extracellular matrix · forelimb · high performance liquid chromatography · histology · horse · joint · physiology · Amino Acids · Animals · Biomechanics · Biopsy · Bisbenzimide · Cartilage, Articular · Chromatography, High Pressure Liquid · Collagen · DNA · Extracellular Matrix · Fluorescent Dyes · Forelimb · Glycosaminoglycans · Horses · Hydroxylysine · Joints · Methylene Blue · Water
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 35 found. Next | Sort by date