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Showing 1 to 14 of 14 found. | Sort by date

1 Glutamate metabolism in ageing rat brain
article 1980    
Author: Koning-Verest, I.F. de
Keywords: Biology · Glutamic acid · Radioisotope · Acetic acid h 3 · Age · Aging · Animal experiment · Brain · Central nervous system · Drug metabolism · Glucose c 14 · In vitro study · Rat · Acetates · Aging · Animal · Aspartic Acid · Brain · Comparative Study · Female · Glucose · Glutamates · Glutamine · Rats
[Abstract]

2 Involvement of aspartic and glutamic residues in kringle-2 of tissue-type plasminogen activator in lysine binding, fibrin binding and stimulation of activity as revealed by chemical modification and oligonucleotide-directed mutagenesis
article 1990    
Author: Weening-Verhoeff, E.J.D. · Quax, P.H.A. · Leeuwen, R.T.J. van · Rehberg, E.F. · Marotti, K.R. · Verheijen, J.H.
Keywords: Health · Chemical modification · Ligand binding · Site directed mutagenesis · Amino Acid Sequence · Aspartic Acid · Base Sequence · Ethyldimethylaminopropyl Carbodiimide · Fibrin · Glutamates · Kinetics · Lysine · Molecular Sequence Data · Mutagenesis, Site-Directed · Mutation · Peptide Fragments · Plasminogen · Protein Engineering · Tissue Plasminogen Activator

3 Collagen turnover in normal and degenerate human intervertebral discs as determined by the racemization of aspartic acid
article 2008    
Author: Sivan, S.-S. · Wachtel, E. · Tsitron, E. · Sakkee, N. · Ham, F. van der · Groot, J.de · Roberts, S. · Maroudas, A.
Keywords: Biology · Acids · Histology · Implants (surgical) · Isomers · Organic acids · Population statistics · Probability density function · Aspartic acids · Collagen molecules · Collagenous tissues · Decreasing functions · Intervertebral discs · Pentosidine · Racemization rates · Statistical analysis · Turnover rates · Dextro aspartic acid · Arginine · Drug derivative · Lysine · Controlled study · Dentin · Half life time · Human tissue · Intervertebral disk · Intervertebral disk degeneration · Isomer · Protein metabolism · Racemization · Statistical analysis · Turnover time · Metabolism · Pathology · Spine disease · Adolescent · Adult · Age Factors · Aged · Arginine · Collagen · D-Aspartic Acid · Dentin · Female · Humans · Intervertebral Disk · Lysine · Male · Middle Aged · Spinal Diseases
[PDF] [Abstract]

4 Effect of collagen turnover on the accumulation of advanced glycation end products
article 2000    
Author: Verzijl, N. · Groot, J. de · Thorpe, S.R. · Bank, R.A. · Shaw, J.N. · Lyons, T.J. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · Baynes, J.W. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · Advanced glycation end product · Aspartic acid · Collagen · N (carboxyethyl)lysine · N (carboxymethyl)lysine · Pentosidine · Unclassified drug · Age · Articular cartilage · Cell survival · Controlled study · Glycation · Human · Human cell · Human tissue · Kinetics · Priority journal · Protein metabolism · Skin · Turnover time · Adolescent · Adult · Age Factors · Aged · Aged, 80 and over · Arginine · Aspartic Acid · Cartilage, Articular · Child · Child, Preschool · Chondrocytes · Collagen · Glycosylation End Products, Advanced · Humans · Kinetics · Lysine · Middle Aged · Skin
[PDF] [Abstract]

5 Aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid
article 2006    
Author: Sivan, S.S. · Tsitron, E. · Wachtel, E. · Roughley, P.J. · Sakkee, N. · Ham, F. van der · Groot, J.de · Roberts, S. · Maroudas, A.
Keywords: Biology · Biomedical Research · Agglomeration · Buoyancy · Cartilage · Synthesis (chemical) · Tissue · Aspartic acid · Non-aggregating molecules · Non-aggregating proteoglycans · Racemization · Organic acids · Aggrecan · Hyaluronic acid · Proteoglycan · Articular cartilage · Controlled study · Human · Human tissue · Racemization · Turnover time · Adolescent · Adult · Aged · Aged, 80 and over · Aggrecans · Aging · Aspartic Acid · Biological Markers · Child · Child, Preschool · Extracellular Matrix Proteins · Humans · Infant · Infant, Newborn · Intervertebral Disk · Lectins, C-Type · Middle Aged · Proteochondroitin Sulfates · Spinal Diseases · Time Factors
[PDF] [Abstract]

6 Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: The use of pentosidine levels as a quantitative measure of protein turnover
article 2001    
Author: Verzijl, N. · Groot, J. de · Bank, R.A. · Bayliss, M.T. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · Maroudas, A. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · Articular cartilage · Osteoarthritis · Pentosidine · Turnover · Aspartic acid · Collagen · Hyaluronic acid · Protein · Binding site · Controlled study · Glycation · Half life time · Human tissue · Protein domain · Protein metabolism · School child · Adolescent · Adult · Aged · Aged, 80 and over · Aggrecans · Aging · Arginine · Cartilage, Articular · Chemical Fractionation · Child · Extracellular Matrix Proteins · Glycosylation End Products, Advanced · Humans · Lectins, C-Type · Lysine · Middle Aged · Osteoarthritis · Proteochondroitin Sulfates · Proteoglycans
[Abstract]

7 Beneficial effects of TCP on soman intoxication in guinea pigs : seizures, brain damage and learning behaviour
article 2001    
Author: Groot, D.M.G. de · Bierman, E.P.B. · Bruijnzeel, P.L.B. · Carpentier, P. · Kulig, B.M. · Lallement, G. · Melchers, B.P.C. · Philippens, I.H.C.H.M. · Huygevoort, A.H.B.M. van
Keywords: Toxicology · 1 (1 (2 thienyl)cyclohexyl)piperidine · 1-(1-(2-thienyl)cyclohexyl)piperidine · Atropine · Chemical warfare agent · Drug derivative · Muscarinic receptor blocking agent · N methyl dextro aspartic acid receptor · Neuroprotective agent · Chemically induced disorder · Discrimination learning · Drug effect · Pathology · Physiology · Animals · Atropine · Behavior, Animal · Brain · Chemical Warfare Agents · Cholinesterase Inhibitors · Discrimination Learning · Electroencephalography · Guinea Pigs · Male · Muscarinic Antagonists · Neuroprotective Agents · Phencyclidine · Pyridostigmine Bromide · Receptors, N-Methyl-D-Aspartate · Seizures · Soman
[Abstract]

8 Single amino acid residue changes in subsite - 1 of inulosucrase from Lactobacillus reuteri 121 strongly influence the size of products synthesized
article 2006    
Author: Ozimek, L.K. · Kralj, S. · Kaper, T. · Maarel, M.J.E.C. van der · Dijkhuizen, L.
Keywords: Food technology · Inulosucrase · Lactobacillus reuteri · Processivity · Site-directed mutagenesis · Amino acid · Arginine · Aspartic acid · Fructan · Fructansucrase · Fructose oligosaccharide · Glutamic acid · Glycosidase · Histidine · Inulin · Inulosucrase · Levan · Lysine · Mutant protein · Oligosaccharide · Polymer · Sucrase · Sucrose · Tryptophan · Unclassified drug · Amino acid sequence · Carbohydrate synthesis · Catalysis · Concentration (parameters) · Controlled study · Enzyme active site · Enzyme activity · Enzyme specificity · Enzyme structure · Enzyme substrate · Glycosylation · Molecular recognition · Molecular size · Nonhuman · Nucleotide sequence · Protein family · Amino Acid Substitution · Binding Sites · Hexosyltransferases · Lactobacillus reuteri · Molecular Weight · Oligosaccharides · Bacillus subtilis · Bacteria (microorganisms) · Lactobacillus reuteri
[PDF] [Abstract]

9 Biochemical and molecular characterization of Lactobacillus reuteri 121 reuteransucrase
article 2004    
Author: Kralj, S. · Geel-Schutten, G.H. van · Maarel, M.J.E.C. van der · Dijkhuizen, L.
Keywords: Nutrition · Food technology · Amino acid · Asparagine · Aspartic acid · Glucan · Glucoside · Glutamic acid · Glutamine · Glycosyltransferase · Oligosaccharide · Reuteransucrase · Sucrase · Sucrose · Unclassified drug · Amino terminal sequence · Bioassay · Carbohydrate synthesis · Carboxy terminal sequence · Catalysis · Controlled study · Deletion mutant · Enzyme activity · Enzyme analysis · Enzyme inactivation · Enzyme kinetics · Lactobacillus reuteri · Leuconostoc · Molecular size · Nonhuman · Priority journal · Protein binding · Sequence alignment · Streptococcus · Amino Acid Sequence · Binding Sites · Gene Deletion · Glucans · Glycosyltransferases · Kinetics · Lactobacillus · Maltose · Molecular Sequence Data · Mutagenesis, Site-Directed · Sucrose · Lactobacillus · Lactobacillus reuteri · Leuconostoc · Streptococcus
[Abstract]

10 Mutational analysis of pea lectin: Substitution of Asn125 for Asp in the monosaccharide-binding site eliminates mannose/glucose-binding activity
article 1992    
Author: Eijsden, R.R. van · Hoedemaeker, F.J. · Díaz, C.L. · Lugtenberg, B.J.J. · Sylvia Pater, B. de · Kijne, J.W.
Keywords: mutagenesis · pea lectin · sugar binding · mannose · oligodeoxyribonucleotide · pea lectin · phytohemagglutinin · amino acid sequence · binding site · chemistry · comparative study · Escherichia coli · genetics · legume · medicinal plant · metabolism · molecular genetics · nucleotide sequence · site directed mutagenesis · structure activity relation · Amino Acid Sequence · Asparagine · Aspartic Acid · Base Sequence · Binding Sites · Calcium · Comparative Study · DNA Mutational Analysis · Escherichia coli · Fabaceae · Glucose · Lectins · Manganese · Mannose · Molecular Sequence Data · Mutagenesis, Site-Directed · Oligodeoxyribonucleotides · Phytohemagglutinins · Plants, Medicinal · Sequence Alignment · Structure-Activity Relationship
[Abstract]

11 Bioavailability of tryptophan from a single oral dose of a trytophan-enriched peptide mixture in healthy men
article 2004    
Author: Brink, E.J. · Boelsma, E. · Steijns, J. · Hendriks, H.F.J.
Keywords: Biology Health · Physiological Sciences · Amino acids · Dietary supplements · Serotonergic activity · Tryptophan · 5 hydroxyindoleacetic acid · 6 hydroxymelatonin o sulfate · Alanine · Arginine · Aspartic acid · Cystine · Glucose · Glutamic acid · Histidine · Insulin · Isoleucine · Leucine · Lysine · Melatonin · Methionine · Phenylalanine · Prolactin · Proline · Protein hydrolysate · Serine · Serotonin · Threonine · Tryptophan · Valine · Adult · Amino acid blood level · Area under the curve · Blood analysis · Brain function · Chemical binding · Clinical trial · Controlled clinical trial · Controlled study · Crossover procedure · Double blind procedure · Drug bioavailability · Human · Human experiment · Insulin blood level · Male · Metabolic parameters · Normal human · Prolactin blood level · Randomized controlled trial · Review · Serotonin blood level · Serotonin brain level · Serotonin metabolism · Urinalysis · Urine level
[Abstract]

12 Inhibition of the central melanocortin system decreases brown adipose tissue activity
article 2014    
Author: Kooijman, S. · Boon, M.R. · Parlevliet, E.T. · Geerling, J.J. · Pol, V. van de · Romijn, J.A. · Havekes, L.M. · Meurs, I. · Rensen, P.C.N.
Keywords: Biology · Energy expenditure · Liver · Triglycerides · Very low density lipoprotein · White adipose tissue · Apolipoprotein E · Fat droplet · Melanocortin · Melanocortin 3 receptor · Melanocortin 4 receptor · N acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide] · Triacylglycerol · Uncoupling protein 1 · Animal experiment · Animal tissue · Body fat · Brown adipose tissue · Central melanocortin system · Controlled study · Dyslipidemia · Endocrine system · Fat mass · Fatty liver · Female · Food intake · Hormone inhibition · Lipid analysis · Lipid oxidation · Lipid storage · Mouse · Nonhuman · Obesity · Signal transduction · Weight gain · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

13 A study of the clinical and radiological features in a cohort of 93 patients with a COL2A1 mutation causing spondyloepiphyseal dysplasia congenita or a related phenotype
article 2015    
Author: Terhal, P.A. · Nievelstein, R.J.A.J. · Verver, E.J.J. · Topsakal, V. · Dommelen, P. van · Hoornaert, K. · Merrer, M. le · Zankl, A. · Simon, M.E. · Smithson, S.F. · Marcelis, C. · Kerr, B. · Clayton-Smith, J. · Kinning, E. · Mansour, S. · Elmslie, F. · Goodwin, L. · Hout, A.H. van der · Veenstra-Knol, H.E. · Herkert, J.C. · Lund, A.M. · Hennekam, R.C. · Mégarbané, A. · Lees, M.M. · Wilson, L.C. · Male, A. · Hurst, J. · Alanay, Y. · Annerén, G. · Betz, R.C. · Bongers, E.M. · Cormier-Daire, V. · Dieux, A. · David, A. · Elting, M.W. · Ende, J. van den · Green, A. · Hagen, J.M. van · Hertel, N.T. · Holder-Espinasse, M. · Hollander, N. den · Homfray, T. · Hove, H.D. · Price S · Raas-Rothschild, A. · Rohrbach, M. · Schroeter, B. · Suri, M. · Thompson, E.M. · Tobias, E.S. · Toutain, A. · Vreeburg, M. · Wakeling, E. · Knoers, N.V. · Coucke, P. · Mortier, G.R.
Keywords: Health · SEDC · Genotype-phenotype · Spondyloepiphyseal dysplasia · Review · SEDC · Aspartic acid · Glycine · Procollagen · Serine · Adolescent · Amino acid substitution · Atlantoaxial dislocation · Bronchomalacia · Child · Cleft palate · Clinical feature · Clubfoot · COL2A1 gene · Coxa vara · Disease severity · Female · Gene · Gene mutation · Genotype phenotype correlation · Gestational age · Hearing impairment · Heterozygosity · Hip arthroplasty · Hypermetropia · Major clinical study · Male · Missense mutation · Mutational analysis · Myopia · Osteotomy · Pierre Robin syndrome · Population research · Respiratory distress · Retina detachment · School child · Scoliosis · Spondyloepiphyseal dysplasia · Tracheomalacia · Tracheostomy · Healthy for Life · Healthy Living · Behavioural Changes · LS - Life Style · ELSS - Earth, Life and Social Sciences
[Abstract]

14 Bace1 activity in cerebrospinal fluid and its relation to markers of ad pathology
article 2010    
Author: Mulder, S.D. · Flier, W.M. van der · Verheijen, J.H. · Mulder, C. · Scheltens, P. · Blankenstein, M.A. · Hack, C.E. · Veerhuis, R.
Keywords: Biology · Biomedical Research · Aβ<sub>-{40}Aβ</sub> · Alzheimer's disease · BACE1 activity · CSF biomarker profile · p-tau · t-tau · {42} · amyloid beta protein[1-40] · amyloid beta protein[1-42] · beta secretase · tau protein · threonine · adult · aged · Alzheimer disease · article · cerebrospinal fluid analysis · clinical article · controlled study · correlational study · enzyme activity · female · human · male · mild cognitive impairment · mini mental state examination · priority journal · protein phosphorylation · Aged · Alzheimer Disease · Amyloid beta-Protein · Amyloid Precursor Protein Secretases · Apolipoproteins E · Aspartic Acid Endopeptidases · Cognition Disorders · Enzyme-Linked Immunosorbent Assay · Female · Humans · Male · Middle Aged · Peptide Fragments · Statistics as Topic · tau Proteins
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 14 of 14 found. | Sort by date