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1 Detection of adducts formed upon treatment of DNA with cisplatin and carboplatin
bookPart 1996    
Author: Fichtinger-Schepman, A.M.J. · Welters, M.J.P. · Dijk-Knijnenburg, H.C.M. van · Sterre, M.L.T. van der · Tilby, M.J. · Berends, F. · Baan, R.A.
Keywords: Nutrition · Animal · Carboplatin · Cell Survival · CHO Cells · Cisplatin · Comparative Study · DNA · DNA Adducts · Enzyme-Linked Immunosorbent Assay · Hamsters · Kinetics · Thiourea
[Abstract]

2 Genotoxicity evaluation of wood-derived and vegetable oil-derived stanol esters
article 1999    
Author: Turnbull, D. · Frankos, V.H. · Delft, J.H.M. van · Vogel, N. de
Keywords: Nutrition · Fatty acid ester · Vegetable oil · Chemical structure · Chromosome aberration · Food safety · Gene mutation · Genotoxicity · Mammal cell · Priority journal · Salmonella typhimurium · Wood · Animals · Carcinogenicity Tests · CHO Cells · Chromosome Aberrations · Cricetinae · DNA Mutational Analysis · Evaluation Studies · Mice · Mutagens · Phytosterols · Plant Oils · Salmonella typhimurium · Tumor Cells, Cultured · Wood · Bacteria (microorganisms) · Mammalia · Salmonella typhimurium · Typhimurium
[Abstract]

3 Effects of thiourea and ammonium bicarbonate on the formation and stability of bifunctional cisplatin-DNA adducts : consequences for the accurate quantification of adducts in (cellular) DNA
article 1995    
Author: Fichtinger-Schepman, A.M.J. · Dijk-Knijnenburg, H.C.M. van · Dijt, F.J. · Velde-Visser, S.D. van der · Berends, F. · Baan, R.A.
Keywords: Nutrition · Ammonium derivative · Bicarbonate · Cell dna · Cisplatin · Dna · Thiourea · Animal cell · Cho cell · Dna adduct · Drug determination · Drug dna interaction · Nonhuman · Animal · Bicarbonates · Cell Survival · CHO Cells · Chromatography, Ion Exchange · Cisplatin · Cricetulus · Deoxyribonucleases · DNA Adducts · Hamsters · Support, Non-U.S. Gov't · Thiourea · Animalia · Cricetinae · Cricetulus griseus
[Abstract]

4 Adenoviral expression of a urokinase receptor - Targeted protease inhibitor inhibits neointima formation in murine and human blood vessels
article 2001    
Author: Quax, P.H.A. · Lamfers, M.L.M. · Lardenoye, J.H.P. · Grimbergen, J.M. · Vries, M.R. de · Slomp, J. · Ruiter, M.C. de · Kockx, M.M. · Verheijen, J.H. · Hinsbergh, V.W.M. van
Keywords: Adenoviridae · Animals · Aprotinin · Blood Vessels · Cattle · CHO Cells · Cricetinae · Femoral Artery · Femoral Vein · Gene Expression · Genetic Vectors · Humans · Mice · Mice, Inbred C57BL · Muscle, Smooth, Vascular · Organ Culture Techniques · Peptide Fragments · Plasmin · Recombinant Fusion Proteins · Saphenous Vein · Transfection · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

5 Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1
article 2002    
Author: Lamfers, M.L.M. · Grimbergen, J.M. · Aalders, M.C. · Havenga, M.J. · Vries, M.R. de · Huisman, L.G.M. · Hinsbergh, V.W.M. van · Quax, P.H.A.
Keywords: Biology · Adenovirus · Matrix metalloproteinases · Neointima formation · Plasmin(ogen) · Urokinase-type plasminogen activator · Adenovirus · Adenoviridae · Animals · Cell Division · Cell Membrane · Cell Movement · Cells, Cultured · CHO Cells · Collagenases · Cricetinae · Culture Media, Conditioned · Enzyme Activation · Flow Cytometry · Gene Transfer Techniques · Humans · Matrix Metalloproteinase 13 · Muscle, Smooth, Vascular · Protein Structure, Tertiary · Receptors, Cell Surface · Recombinant Fusion Proteins · RNA, Messenger · Saphenous Vein · Tissue Inhibitor of Metalloproteinase-1 · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

6 Safety evaluation of β-glucanase derived from Trichoderma reesei: Summary of toxicological data
article 1995    
Author: Coenen, T.M.M. · Schoenmakers, A.C.M. · Verhagen, H.
Keywords: Toxicology · barlican · beta glucan hydrolase · unclassified drug · animal experiment · article · chicken · chronic toxicity · controlled study · eye irritation · female · guinea pig · male · mutagenicity · nonhuman · rabbit · rat · skin irritation · skin sensitization · Administration, Oral · Animal · Animal Feed · beta-Glucosidase · Biological Products · Chickens · CHO Cells · Dermatitis, Contact · Environmental Exposure · Female · Food Additives · Guinea Pigs · Hamsters · Lethal Dose 50 · Male · Mutagenicity Tests · No-Observed-Adverse-Effect Level · Rabbits · Rats · Rats, Wistar · Salmonella typhimurium · Toxicity Tests · Trichoderma · Animalia · Cavia porcellus · Gallus gallus · Hypocrea jecorina · Oryctolagus cuniculus · Sus scrofa · Trichoderma
[Abstract]

7 QSAR models for predicting in vivo aquatic toxicity of chlorinated alkanes to fish
article 2008    
Author: Zvinavashe, E. · Berg, H. van den · Soffers, A.E.M.F. · Vervoort, J. · Freidig, A. · Murk, A.J. · Rietjens, I.M.C.M.
Keywords: Physiological Sciences · 1 chloro 2 methylbutane · 1 chloro 2,2 dimethylpropane · 1 chlorodecane · 1 chlorododecane · 1 chloroheptane · 1 chlorohexane · 1 chlorononane · 1 chlorooctane · 1 chloropentane · 1,1 dichloro 3,3 dimethylbutane · 1,1,2 trichloroethane · 1,10 dichlorodecane · 1,2 dichlorobutane · 1,2 dichloropropane · 1,3 dichloropropane · 1,6 dichlorohexane · 1,8 dichlorooctane · 1,9 dichlorononane · alkane derivative · carbon · carbon tetrachloride · chlorine · tetrachloroethane · animal cell · animal experiment · aquatic environment · article · cell viability · chlorination · CHO cell · controlled study · cytotoxicity · fish · hydrophobicity · nonhuman · quantitative structure activity relation · Algorithms · Animals · Artificial Intelligence · Cell Survival · Chemistry, Physical · CHO Cells · Cricetinae · Cricetulus · Fishes · Hydrocarbons, Chlorinated · Predictive Value of Tests · Quantitative Structure-Activity Relationship · Tetrazolium Salts · Thiazoles · Animalia · Cricetulus griseus
[Abstract]

8 Synthesis and biological evaluation of disubstituted N6- cyclopentyladenine analogues: The search for a neutral antagonist with high affinity for the adenosine A1 receptor
article 2004    
Author: Ligt, R.A.F. de · Klein, P.A.M. van der · Frijtag Drabbe Künzel, J.K. von · Lorenzen, A. · El Maate, F.A. · Fujikawa, S. · Westhoven, R. van · Hoven, T. van den · Brussee, J. · Ijzerman, A.P.
Keywords: Biology Toxicology · Physiological Sciences · [35S]GTPγS binding · Adenosine A1 receptor · Inverse agonism · N-0840 derivatives · Neutral antagonist · 8 bromo 9 methyladenine · 8 bromo n 6 cyclopentyl 9 methyladenine · 8 bromo n 6 cyclopentyl 9 propyladenine · 9 allyl 8 bromo n 6 cyclopentyladenine · 9 allyl n 6 cyclopentyl 8 methoxyadenine · adenine derivative · adenosine A1 receptor antagonist · luf 5666 · luf 5668 · luf 5669 · luf 5674 · n 0840 · n 6 cyclopentyl 8 (ethylthio) 9 methyladenine · n 6 cyclopentyl 8 (n ethyl n butylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methyl n ethylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methyl n propylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methylamino) 9 methyladenine · n 6 cyclopentyl 8 (n methylisopropylamino) 9 methyladenine · n 6 cyclopentyl 8 (n piperidino) 9 methyladenine · n 6 cyclopentyl 8 (n pyrrolidino) 9 methyladenine · n 6 cyclopentyl 8 (n,n diethylamino) 9 methyladenine · n 6 cyclopentyl 8 ethoxy 9 methyladenine · n 6 cyclopentyl 8 isopropoxy 9 methyladenine · n 6 cyclopentyl 8 methoxy 9 methyladenine · n 6 cyclopentyl 8 methoxy 9 propyladenine · n 6 cyclopentyl 9 methyl 8 oxoadenine · n 6 cyclopentyl 9 methyl 8 propoxyadenine · n 6 cyclopentyl 9 methyladenine · unclassified drug · article · binding affinity · drug determination · drug synthesis · drug tolerability · receptor affinity · substitution reaction · Adenine · Adenosine · Animals · Cell Line · CHO Cells · Cricetinae · Drug Evaluation, Preclinical · Humans · Receptor, Adenosine A1
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date