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Showing 1 to 15 of 15 found. | Sort by date

1 Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro
article 2005    
Author: Erk, M.J. van · Roepman, P. · Lende, T.R. van der · Stierum, R.H. · Aarts, J.M.M.J.G. · Bladeren, P.J. van · Ommen, B. van
Keywords: Health Biology · Biomedical Research · (anti-)carcinogenic mechanisms · Caco-2 · Cell proliferation · Gene expression · Quercetin · beta catenin · mitogen activated protein kinase · quercetin · T cell factor protein · antineoplastic activity · apoptosis · article · cancer cell · cell adhesion · cell cycle · cell cycle G1 phase · cell differentiation · cell interaction · cell proliferation · cell strain CACO 2 · cellular distribution · colon carcinoma · controlled study · DNA microarray · down regulation · drug activity · energy metabolism · gene expression · genetic analysis · human · human cell · in vitro study · nucleotide sequence · oncogene · signal transduction · tumor suppressor gene · unindexed sequence · upregulation · Antineoplastic Agents · Apoptosis · Caco-2 Cells · Cell Cycle · Cell Division · Colonic Neoplasms · Dose-Response Relationship, Drug · Gene Expression · Gene Expression Profiling · Gene Expression Regulation · Humans · Quercetin
[Abstract]

2 Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation
article 2007    
Author: Staal, Y.C.M. · Hebels, D.G.A.J. · Herwijnen, M.H.M. van · Gottschalk, R.W.H. · Schooten, F.J. van · Delft, J.H.M. van
Keywords: Toxicology and Applied Pharmacology · benzo[a]pyrene · benzo[b]fluoranthene · dibenz[a,h]anthracene · dibenzo[a,l]pyrene · fluoranthene · phenanthrene derivative · polycyclic aromatic hydrocarbon · apoptosis · article · carcinogenesis · carcinogenicity · cell cycle · cell strain HepG2 · controlled study · DNA adduct · exposure · gene expression · hepatoma cell · human · human cell · nucleotide sequence · priority journal · unindexed sequence · Air Pollutants · Apoptosis · Cell Cycle · Cell Line, Tumor · DNA Adducts · Drug Antagonism · Drug Synergism · Gene Expression Profiling · Gene Expression Regulation, Neoplastic · Humans · Polycyclic Hydrocarbons, Aromatic
[Abstract]

3 Time series analysis of benzo[a]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets
article 2010    
Author: Delft, J.H.M. van · Mathijs, K. · Staal, Y.C.M. · Herwijnen, M.H.M. van · Brauers, K.J.J. · Boorsma, A. · Kleinjans, J.C.S.
Keywords: Nutrition · Biomedical Research · Carcinogen · Network · Time series · Transcription factor · Transcriptome · benzo[a]pyrene · immunoglobulin enhancer binding protein · Myc protein · serum response factor · transcription factor · transcription factor AP 1 · transcription factor E2F1 · transcriptome · amino acid metabolism · apoptosis · article · carcinogenesis · cell cycle G1 phase · cell cycle S phase · controlled study · correlation analysis · DNA adduct · DNA repair · down regulation · functional genomics · gene expression · gene regulatory network · hepatoma cell · human · human cell · lipid metabolism · named inventories, questionnaires and rating scales · proto oncogene · Short Time series Expression Miner · signal transduction · time series analysis · transcription regulation · tumor suppressor gene · upregulation
[Abstract]

4 Effects of feeding stannous chloride on different parts of the gastrointestinal tract of the rat
article 1985    
Author: Janssen, P.J.M. · Bosland, M.C. · Hees, J.P. van
Keywords: Nutrition · Radioisotope · Tin chloride · Animal experiment · Autoradiography · Blood and hemopoietic system · Electron microscopy · Food contamination · Intoxication · Nonhuman · Small intestine · Animal · Body Weight · Cell Cycle · Comparative Study · Diet · Gastrointestinal System · Hemoglobins · Intestine, Small · Male · Microscopy · Microscopy, Electron, Scanning · Organ Weight · Rats · Rats, Inbred Strains · Tin
[Abstract]

5 SFTG international collaborative study on in vitro micronucleus test. II. Using human lymphocytes
article 2006    
Author: Clare, M.G. · Lorenzon, G. · Akhurst, L.C. · Marzin, D. · Delft, J. van · Montero, R. · Botta, A. · Bertens, A. · Cinelli, S. · Thybaud, V. · Lorge, E.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Aneugen · Clastogen · Cytochalasin B · Human lymphocytes · In vitro micronucleus assay · aneugen · bleomycin · clofibrate · colchicine · cytarabine · cytochalasin B · diethylstilbestrol · fluorouracil · mannitol · mitomycin C · tiabendazole · urethan · adult · article · cell culture · cell cycle · cell division · cell nucleus · chemical analysis · controlled study · data analysis · female · human · human cell · lymphocyte · male · micronucleus test · mitogenicity · mononuclear cell · priority journal · reproducibility · sensitivity analysis · Adult · Aneugens · Bleomycin · Clofibrate · Colchicine · Cytarabine · Diethylstilbestrol · Female · Fluorouracil · Humans · International Cooperation · Lymphocytes · Male · Mannitol · Micronucleus Tests · Mutagens · Thiabendazole · Urethane
[Abstract]

6 Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells
article 2004    
Author: Erk, M.J. van · Teuling, E. · Staal, Y.C.M. · Huybers, S. · Bladeren, P.J. van · Aarts, J.M.M.J.G. · Ommen, B. van
Keywords: Health Drugs · Physiological Sciences · complementary DNA · curcumin · cytochrome P450 · functional group · metallothionein · protein p53 · cancer cell culture · cell adhesion · cell cycle G2 phase · cell strain CACO 2 · cell strain HT29 · cell type · colon cancer · colon carcinogenesis · concentration response · controlled study · DNA microarray · DNA repair · down regulation · exposure · flow cytometry · gene expression profiling · genetic transcription · human · human cell · nucleotide sequence · phase transition · review · sensitivity analysis · signal transduction · time · unindexed sequence · xenobiotic metabolism
[Abstract]

7 Low doses of UVB or UVA induce chromosomal aberrations in cultured human skin cells
article 2000    
Author: Emri, G. · Wenczl, E. · Erp, P. van · Jans, J. · Roza, L. · Horkay, I. · Schothorst, A.A.
Keywords: Nutrition · Human fibroblasts · Human melanocytes · Micronuclei · Skin cancer · 1,6 diphenyl 1,3,5 hexatriene · Ethidium bromide · Cell kinetics · Chromosome aberration · Fibroblast · Flow cytometry · Human · Human cell · Ionizing radiation · Priority journal · Skin carcinogenesis · Skin disease · Ultraviolet radiation · Cell Cycle · Cells, Cultured · Chromosome Aberrations · Dose-Response Relationship, Radiation · Fibroblasts · Flow Cytometry · Gamma Rays · Humans · Lasers · Melanocytes · Micronuclei, Chromosome-Defective · Radiation Dosage · Skin · Sunlight · Time Factors · Ultraviolet Rays
[Abstract]

8 Differential modulation by Akkermansia muciniphila and faecalibacterium prausnitzii of host peripheral lipid metabolism and histone acetylation in mouse gut organoids
article 2014    
Author: Lukovac, S. · Belzer, C. · Pellis, L. · Keijser, B.J. · Vos, W.M. de · Montijn, R.C. · Roeselers, G.
Keywords: Biology · G protein coupled receptor 43 · Histone deacetylase · Membrane protein · Peroxisome proliferator activated receptor gamma · Protein Fiaf · Short chain fatty acid · Unclassified drug · Adult · Animal experiment · Animal tissue · Bacterial strain · Cell cycle regulation · Cell metabolism · Controlled study · Down regulation · Epigenetics · Ex vivo study · Fiaf gene · Gene · Gene control · Gene expression · Gene silencing · Gpr43 gene · Hdac3 gene · Hdac5 gene · Histone acetylation · Host pathogen interaction · Ileum · In vivo study · Intestine flora · Lipid metabolism · Lipolysis · Male · Mouse · Nonhuman · Nucleotide sequence · Ppargamma gene · Satiety · Transcription regulation · Akkermansia muciniphila · Faecalibacterium prausnitzii · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

9 Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis
article 2008    
Author: Dihal, A.A. · Woude, H. van der · Hendriksen, P.J.M. · Charif, H. · Dekker, L.J. · IJsselstijn, L. · Boer, V.C.J. de · Alink, G.M. · Burgers, P.C. · Rietjens, I.M.C.M. · Woutersen, R.A. · Stierum, R.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Biomarker · Colorectal cancer · Quercetin · Transcriptomics · fatty acid · glutathione peroxidase 2 · heat shock protein · mitogen activated protein kinase · peroxisome proliferator activated receptor alpha · quercetin · transcriptome · animal experiment · animal model · article · cancer prevention · cell cycle · colon mucosa · colorectal cancer · controlled study · down regulation · energy metabolism · Fischer 344 rat · gene expression · gene targeting · genetic analysis · glycolysis · lipid degradation · male · nonhuman · nucleotide sequence · priority journal · proteomics · rat · statistical significance · tumor biopsy · Animals · Colon · Colorectal Neoplasms · Diet · Down-Regulation · Fatty Acids · Gene Expression Profiling · Glycolysis · Intestinal Mucosa · Male · Mitochondria · Proteome · Quercetin · Rats · Rats, Inbred F344 · Rattus
[Abstract]

10 Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
article 2015    
Author: Schmeits, P.C.J. · Schaap, M.M. · Luijten, M. · Someren, E. van · Boorsma, A. · Loveren, H. van · Peijnenburg, A.A.C.M. · Hendriksen, P.J.M.
Keywords: Biology · C57BL/6 · CTLL-2 · Cyclosporine A · Interspecies comparison · Splenocytes · Interleukin 2 · Messenger RNA · Transcription factor Nrf2 · Animal cell · Animal experiment · Cell cycle regulation · Controlled study · Cytotoxic T lymphocyte · Down regulation · Endoplasmic reticulum stress · HepG2 cell line · Human · Human cell · Immune response · Immunotoxicity · In vitro study · In vivo study · Jurkat cell line · Male · Mouse · Nonhuman · Dpleen cell · T lymphocyte activation · Thymoma cell line · Transcriptomics · Unfolded protein response · Upregulation · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

11 A 16-Residue Peptide Fragment of Macrophage Migration Inhibitory Factor, MIF-(50-65), Exhibits Redox Activity and Has MIF-like Biological Functions
article 2003    
Author: Nguyen, M.T. · Beck, J. · Lue, H. · Fünfzig, H. · Kleemann, R. · Koolwijk, P. · Kapurniotu, A. · Bernhagen, J.
Keywords: Biology · Biomedical Research · Cells · Conformations · Enzymes · Molecular biology · Redox reactions · Phosphorylation · Biochemistry · Animalia · 3T3 Cells · Amino Acid Motifs · Amino Acid Sequence · Animals · Biotinylation · Catalysis · Cell Cycle Proteins · Cell Division · Cells, Cultured · Chromatography, High Pressure Liquid · Circular Dichroism · Cyclin-Dependent Kinase Inhibitor p27 · Cysteine · Disulfides · Endocytosis · Endothelium, Vascular · Glutathione · Humans · Inflammation · Kinetics · Macrophage Migration-Inhibitory Factors · Mass Spectrometry · Mice · Mitogen-Activated Protein Kinase 1 · Mitogen-Activated Protein Kinase 3 · Mitogen-Activated Protein Kinases · Molecular Sequence Data · Oxidation-Reduction · Oxygen · Peptides · Phosphorylation · Protein Binding · Protein Conformation · Serine · Signal Transduction · Sulfhydryl Compounds · Time Factors · Tumor Suppressor Proteins
[PDF] [Abstract]

12 TR3 orphan receptor is expressed in vascular endothelial cells and mediates cell cycle arrest
article 2003    
Author: Arkenbout, E.K. · Bragt, M. van · Eldering, E. · Bree, C. van · Grimbergen, J.M. · Quax, P.H.A. · Pannekoek, H. · Vries, C.J.M. de
Keywords: Biology · Biomedical Research · Endothelial cells · TR3 orphan receptor · Vascular biology · Cell nucleus receptor · Cyclin A · Messenger RNA · Mitogen induced nuclear orphan receptor · Nerve growth factor receptor · Nuclear orphan receptor of t cells · Protein · Protein subunit · Receptor subtype · Thymidine · Unclassified drug · Adenovirus · Atherosclerosis · Blood vessel · Controlled study · Down regulation · Endothelium cell · Gene expression · Gene overexpression · Human cell · Medical assessment · Nonhuman · Nucleotide sequence · Protein expression · Smooth muscle fiber · Upregulation · Virus culture · Adenoviridae · Cell Cycle · Cell Division · Cells, Cultured · DNA, Complementary · Endothelium, Vascular · Gene Expression Regulation · Gene Transfer Techniques · Humans · Peptides · Protein Structure, Tertiary · Receptors, Steroid · Receptors, Thyroid Hormone · Sequence Deletion · Stem Cells · Trans-Activation (Genetics) · Umbilical Veins · Variation (Genetics) · Virus Replication
[Abstract]

13 Design and production in Aspergillus niger of a chimeric protein associating a fungal feruloyl esterase and a clostridial dockerin domain
article 2004    
Author: Levasseur, A. · Pagès, S. · Fierobe, H.-P. · Navarro, D. · Punt, P. · Belaïch, J.-P. · Asther, M. · Record, E.
Keywords: Biology · Biotechnology · Amino acids · Bacteria · Bioassay · Electrophoresis · Enzymes · Fungi · Feruloyl esterase A (FAEA) · Fungal enzymes · Intracellular production · Western blotting · Proteins · antibody · bacterial protein · cell protein · chimeric protein · cohesin · esterase · fungal enzyme · glucan 1,4 alpha glucosidase · hybrid protein · protein dockerin · protein feruloyl esterase A · unclassified drug · enzyme · fungus · microbiology · protein · amino acid sequence · article · Aspergillus niger · cellular distribution · Clostridium thermocellum · complex formation · enzyme activity · enzyme binding · enzyme substrate complex · molecular weight · nonhuman · Northern blotting · polyacrylamide gel electrophoresis · posttranscriptional gene silencing · protein degradation · protein domain · protein processing · protein protein interaction · protein secretion · transcription initiation · Western blotting · Aspergillus niger · Bacterial Proteins · Biotechnology · Carboxylic Ester Hydrolases · Carrier Proteins · Cell Cycle Proteins · Chromosomal Proteins, Non-Histone · Clostridium thermocellum · Fungal Proteins · Nuclear Proteins · Recombinant Fusion Proteins · Transcription, Genetic · Transformation, Genetic · Actinobacteria (class) · Aspergillus · Aspergillus niger · Bacteria (microorganisms) · Clostridium · Clostridium thermocellum · Fungi · Posibacteria · uncultured actinomycete
[PDF] [Abstract]

14 Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
article 2007    
Author: Pires, N.M.M. · Pols, T.W.H. · Vries, M.R. de · Tiel, C.M.van · Bonta, P.I. · Vos, M. · Arkenbout, E.K. · Pannekoek, H. · Jukema, J.W. · Quax, P.H.A. · Vries, C.J.M. de
Keywords: Biology · Biomedical Research · Muscle, smooth · Receptors, cytoplasmic and nuclear · Restenosis · Stents · Transcription factors · cyclin dependent kinase inhibitor 1B · cycline · mercaptopurine · messenger RNA · nuclear receptor Nur77 · polycaprolactone · small interfering RNA · staurosporine · thymidine · tritium · animal experiment · animal model · animal tissue · antiangiogenic activity · antigen expression · apoptosis · artery intima proliferation · article · blood vessel injury · blood vessel wall · cell culture · cell cycle arrest · cell proliferation · controlled study · DNA synthesis · drug delivery system · drug dose comparison · drug effect · elution · experimental model · femoral artery · gene overexpression · human · human cell · hypothesis · in-stent restenosis · inflammation · intima · local therapy · male · mouse · nonhuman · observation · priority journal · protein expression · receptor down regulation · receptor upregulation · smooth muscle fiber · sustained drug release · transgenic mouse · vascular smooth muscle · wild type · 6-Mercaptopurine · Animals · Antimetabolites, Antineoplastic · Apoptosis · Cell Division · Cells, Cultured · Coronary Restenosis · Disease Models, Animal · DNA-Binding Proteins · Drug Implants · Femoral Artery · Humans · Male · Mice · Mice, Inbred Strains · Mice, Transgenic · Muscle, Smooth, Vascular · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · RNA, Small Interfering · Transcription Factors · Tunica Intima · Umbilical Arteries
[PDF] [Abstract]

15 GIT1 Mediates Thrombin Signaling in Endothelial Cells: Role in Turnover of RhoA-Type Focal Adhesions
article 2004    
Author: Nieuw Amerongen, G.P. van · Natarajan, K. · Yin, G. · Hoefen, R.J. · Osawa, M. · Haendeler, J. · Ridley, A.J. · Fujiwara, K. · Hinsbergh, V.W.M. van · Berk, B.C.
Keywords: Biology · Biomedical Research · Contractility · Endothelium · Focal adhesion kinase · Thrombin · 4 (1 aminoethyl) n (4 pyridyl)cyclohexanecarboxamide · antisense oligonucleotide · focal adhesion kinase · G protein coupled receptor kinase · G protein coupled receptor kinase interacting protein · GIT1 protein · guanosine triphosphatase · protein tyrosine kinase · Rho kinase · RhoA guanine nucleotide binding protein · thrombin · unclassified drug · vinculin · Adenovirus · animal cell · article · cell migration · cell shape · cell structure · cellular distribution · controlled study · depletion · endothelium cell · enzyme activation · enzyme metabolism · enzyme phosphorylation · enzyme substrate · focal adhesion · genetic transfection · human · human cell · membrane permeability · negative feedback · nonhuman · priority journal · protein function · protein localization · protein phosphorylation · protein protein interaction · protein transport · regulatory mechanism · signal transduction · umbilical vein · Adaptor Proteins, Signal Transducing · Amides · Animals · Aorta · Cattle · Cell Cycle Proteins · Cell Size · Cells, Cultured · Endothelial Cells · Endothelium, Vascular · Enzyme Inhibitors · Feedback, Biochemical · Focal Adhesion Kinase 1 · Focal Adhesion Protein-Tyrosine Kinases · Focal Adhesions · GTPase-Activating Proteins · Humans · Oligodeoxyribonucleotides, Antisense · Phosphoproteins · Phosphorylation · Protein Processing, Post-Translational · Protein Transport · Protein-Tyrosine Kinases · Proto-Oncogene Proteins pp60(c-src) · Pyridines · rac GTP-Binding Proteins · rhoA GTP-Binding Protein · RNA, Small Interfering · Signal Transduction · Thrombin · Transduction, Genetic · Transfection · Umbilical Veins · Vinculin
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 15 of 15 found. | Sort by date