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Showing 1 to 6 of 6 found. | Sort by date

1 Dietary n-6 and n-3 polyunsaturated fatty acids and colorectal carcinogenesis : results from cultured colon cells, animal models and human studies
article 2002    
Author: Dommels, Y.E.M. · Alink, G.M. · Bladeren, P.J. van · Ommen, B. van
Keywords: Environment · Animal models · Biomarkers · Colorectal carcinogenesis · Dietary n-6 and n-3 fatty acids · Epidemiology · Human colorectal carcinoma cell lines
[Abstract]

2 Characterizing the invasion of different breast cancer cell lines with distinct E-cadherin status in 3D using a microfluidic system
article 2019    
Author: Amirabadi, H. Eslami · Tuerlings, M. · Hollestelle, A. · SahebAli, S. · Luttge, R. · Donkelaar, C.C. van · Martens, J.W.M. · Toonder, J.M.J. den
Keywords: Breast cancer cell lines · Cancer invasion · Chemotactic gradient · Microfluidics · Cell adhesion · Cell culture · Fluidic devices · Glycoproteins · Microfluidics · Breast cancer cells · Cancer invasion · E-cadherin expression · E-cadherins · Invasion mode · Investigate effects · Micro fluidic system · Tumor microenvironment · Diseases
[PDF] [Abstract]

3 Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling.
article 2014    
Author: Bosgra, S. · Steeg, E. van de · Vlaming, M.L. · Verhoeckx, K.C. · Huisman, M.T. · Verwei, M. · Wortelboer, H.M.
Keywords: Biology · Transporter · Hepatic disposition · Transfected cell-lines · Protein abundance · LC–MS · Hepatic disposition · OATP · PBPK model · Polymorphisms · Protein abundance · Transfected cell-lines · Drug carrier · Organic anion transporter B · Rosuvastatin · Solute carrier organic anion transporter 1B1 · Solute carrier organic anion transporter 1B3 · Controlled study · Drug clearance · Drug disposition · Drug transport · Enterohepatic circulation · Gene overexpression · Genetic transfection · Genetic variability · HEK293 cell line cell tissue · In vitro study · In vivo study · Intrinsic clearance · Liquid chromatography · Liver · Liver cell · Model · Outer membrane · Physiology based pharmacokinetic model · Prediction · Protein analysis · Simulation · Single drug dose · Tandem mass spectrometry · Food and Nutrition · Healthy Living · Life · RAPID - Risk Assessment Products in Development MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

4 Monolayers of IEC-18 cells as an in vitro model for screening the passive transcellular and paracellular transport across the intestinal barrier: Comparison of active and passive transport with the human colon carcinoma Caco-2 cell line
article 2002    
Author: Versantvoort, C.H.M. · Ondrewater, R.C.A. · Duizer, E. · Sandt, J.J.M. van de · Gilde, A.J. · Groten, J.P.
Keywords: Caco-2 · Carrier-mediated transport · H+-di/tripeptide carrier · IEC-18 · Intestinal cell lines · MRP · P-Glycoprotein · acetylsalicylic acid · calcein · carrier protein · dinitrophenylglutathione · glucose derivative · glutathione derivative · glycoprotein P · glycylsarcosine · hydrocortisone · macrogol 4000 · mannitol · methylglucose · multidrug resistance protein · probenecid · propranolol · rhodamine 123 · salicylic acid · testosterone · unclassified drug · verapamil · vincristine · animal cell · article · cell membrane permeability · cell strain CACO 2 · cell transport · colon carcinoma · controlled study · drug transport · human · human cell · in vitro study · ion transport · model · nonhuman · priority journal · protein expression · rat · screening
[Abstract]

5 Expression profiling of colon cancer cell lines and colon biopsies: Towards a screening system for potential cancer-preventive compounds
article 2005    
Author: Erk, M.J. van · Krul, C.A.M. · Caldenhoven, E. · Stierum, R.H. · Peters, W.H. · Woutersen, R.A. · Ommen, B. van
Keywords: Health · Toxicology and Applied Pharmacology · Cancer prevention · Cell lines · Colon biopsies · Colon cancer · Expression profiling · APC protein · Beta catenin · Complementary DNA · Cyclooxygenase 2 · Protein p53 · Adult · Cancer cell culture · Cancer prevention · Cancer research · Cancer screening · Cancer staging · Clinical article · Colon biopsy · Colon cancer · Controlled study · Data analysis · DNA microarray · Female · Gene expression · Genetic analysis · Human · Human cell · Hybridization · Immune response gene · Male · Mutation · Nucleotide sequence · Oncogene c myc · Oncogene ras · Principal component analysis · Priority journal · Protein expression · RNA isolation · Tumor suppressor gene · Adenocarcinoma · Adult · Biopsy · Cell Line, Tumor · Colonic Neoplasms · Female · Gastric Mucosa · Gene Expression Profiling · Gene Expression Regulation, Neoplastic · Genes, Neoplasm · Genetic Screening · Humans · Male · Middle Aged · Mutation, Missense · Neoplasm Proteins · Oligonucleotide Array Sequence Analysis · RNA, Neoplasm · Tumor Markers, Biological
[Abstract]

6 Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity
article 2006    
Author: Boerboom, A.M.J.F. · Vermeulen, M. · Woude, H. van der · Bremer, B.I. · Lee-Hilz, Y.Y. · Kampman, E. · Bladeren, P.J. van · Rietjens, I.M.C.M. · Aarts, J.M.M.J.G.
Keywords: Biology · Benzyl isothiocyanate · Fisetin · Glutathione transferase · Kaempferol · Luteolin · Myricetin · Quercetin · Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone) · Taxifolin · Tert butylhydroquinone · Animal cell · Antioxidant activity · Cancer cell culture · Cancer screening · Chemoprophylaxis · Controlled study · Drug potency · Drug structure · Electrophile responsive element mediated gene · Enzyme induction · Gene · Gene activation · Gene expression · Gene induction · Genetic transcription · Human cell · Molecular interaction · Mouse · Nonhuman · Reporter gene · Screening test · Stereospecificity · Structure activity relation · Tandem repeat · Transcription initiation · Validation study · Animals · Base Sequence · Cell Line · DNA Primers · Enzyme Induction · Flavonoids · Gene Expression · Genes, Reporter · Humans · Luciferases · Mice · Plasmids · Structure-Activity Relationship · Transcription, Genetic · Benzyl isothiocyanate · Electrophile-responsive element (EpRE) · Hepa-1c1c7 cells · Stable luciferase reporter cell lines · Transient transfection
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 6 of 6 found. | Sort by date