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Showing 1 to 16 of 16 found. | Sort by date

1 Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2
article 2008    
Author: Wortelboer, H.M. · Balvers, M.G.J. · Usta, M. · Bladeren, P.J. van · Cnubben, N.H.P.
Keywords: Health · Physiological Sciences · Arsenic trioxide · Cisplatin · Glutathione · Mercury chloride · MRP1 · MRP2 · Adenosine triphosphatase · Calcein · Cisplatin · Glutathione · Multidrug resistance protein 1 · Multidrug resistance protein 2 · Animal cell · Cell viability · Complex formation · Controlled study · Enzyme activity · Kidney cell · Membrane vesicle · Molecular interaction · Nonhuman · Protein expression · Transport kinetics
[Abstract]

2 Assessment of some critical factors in the freezing technique for the cryopreservation of precision-cut rat liver slices
article 2000    
Author: Maas, W.J.M. · Graaf, I.A.M. de · Schoen, E.D. · Koster, H.J. · Sandt, J.J.M. van de · Groten, J.P.
Keywords: Production · Technology · Food · Adenosine triphosphate · Cryoprotective agent · Glutathione · Lactate dehydrogenase · Potassium · Testosterone · Animal tissue · Cell death · Cell metabolism · Cell viability · Controlled study · Cryopreservation · Enzyme activity · Freezing · Liver preservation · Male · Nonhuman · Priority journal · Protein content · Rat · Technique · Adenosine Triphosphate · Animals · Cryopreservation · Dinitrochlorobenzene · Evaluation Studies · Glutathione · Glutathione Transferase · L-Lactate Dehydrogenase · Liver · Male · Microtomy · Potassium · Proteins · Rats · Rats, Wistar · Testosterone · Tissue Preservation · Urea · Animalia
[Abstract]

3 Effects of saponins and glycoalkaloids on the permeability and viability of mammalian intestinal cells and on the integrity of tissue preparations in vitro
article 1996    
Author: Gee, J.M. · Wortley, G.M. · Johnson, I.T. · Price, K.R. · Rutten, A.A.J.J.L. · Houben, G.F. · Penninks, A.H.
Keywords: Toxicology · Alkaloid · Chaconine · Lactate dehydrogenase · Saponin · Solanine · Tomatine · Unclassified drug · Animal cell · Cell culture · Cell membrane · Cell viability · Chemical interaction · Controlled study · Cytotoxicity · Human · Human cell · In vitro study · Intestine epithelium · Intestine mucosa · Jejunum · Membrane depolarization · Membrane permeability · Nonhuman · Rat · Gypsophila spp. · Lycopersicon esculentum · Solanum tuberosum
[Abstract]

4 Comparison of five incubation systems for rat liver slices using functional and viability parameters
article 1997    
Author: Olinga, P. · Groen, K. · Hof, I.H. · Kanter, R. de · Koster, H.J. · Leeman, W.R. · Rutten, A.A.J.J.L. · Twillert, K. van · Groothuis, G.M.M.
Keywords: Incubation system · Rat liver slices · Vaibility · Lidocaine · Phenazone · Testosterone · Animal tissue · Cell viability · Controlled study · Culture medium · Drug metabolism · Incubation time · Liver microsome metabolism · Liver slice · Nonhuman · Preservation · Animals · Energy Metabolism · L-Lactate Dehydrogenase · Liver · Male · Organ Culture Techniques · Potassium · Rats · Rats, Wistar · Xenobiotics · Animalia
[Abstract]

5 Skin irritation and corrosion
article 2005    
Author: Zuang, V. · Alonso, M.A. · Botham, P.A. · Eskes, C. · Fentem, J. · Liebsch, M. · Sandt, J.J.M. van de
Keywords: Chemistry Safety · Food and Chemical Risk Analysis · cosmetic · acute toxicity · animal testing alternative · cell growth · cell viability · chemical structure · corrosion · electric resistance · explant · human · in vitro study · model · pH measurement · priority journal · reproducibility · review · safety · skin culture · skin irritation · skin water loss · standardization · toxicity testing · validation process · Animal Testing Alternatives · Animals · Cell Survival · Consumer Product Safety · Cosmetics · Endpoint Determination · European Union · Humans · Irritants · Organ Culture Techniques · Quantitative Structure-Activity Relationship · Skin · Skin Irritancy Tests · Swine · Animalia

6 Effects of cadmium chloride on the paracellular barrier function of intestinal epithelial cell lines
article 1999    
Author: Duizer, E. · Gilde, A.J. · Versantvoort, C.H.M. · Groten, J.P.
Keywords: Nutrition · Caco-2 · Cadmium · IEC-18 · Tight junction · Cadmium chloride · Macrogol 4000 · Annitol · Occludin · Uvomorulin · Animal tissue · Apical membrane · Cell junction · Cell viability · Cellular distribution · Cytotoxicity · Electric resistance · Human · Human tissue · Intestine mucosa permeability · Long term exposure · Molecular size · Nonhuman · Tight junction · Transcytosis · Animals · Caco-2 Cells · Cadherins · Cadmium Chloride · Cadmium Radioisotopes · Cell Membrane Permeability · Cell Survival · Cells, Cultured · Epithelial Cells · Humans · Ileum · Intestinal Absorption · Mannitol · Membrane Proteins · Phosphoproteins · Polyethylene Glycols · Rats · Tight Junctions · Animalia
[Abstract]

7 Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle
article 1996    
Author: Vliet, A.K. van · Nègre-Arrariou, P. · Thiel, G.C.F. van · Bolhuis, P.A. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitors · Human myoblasts · Sterol synthesis · Adenosine triphosphate · Hydroxymethylglutaryl coenzyme a reductase inhibitor · Mevinolin · Mitochondrial enzyme · Cell culture · Cell proliferation · Cell viability · Concentration response · Controlled study · Dna synthesis · Human cell · Human tissue · Muscle biopsy · Myoblast · Myopathy · Skeletal muscle · Acetic Acid · Adenosine Triphosphate · Anticholesteremic Agents · Cell Division · Cell Survival · Cells, Cultured · DNA · Enzyme Inhibitors · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Mitochondria · Muscle, Skeletal · Oxidoreductases · Pravastatin · Simvastatin · Sterols
[Abstract]

8 Absorption enhancement, structural changes in tight junctions and cytotoxicity caused by palmitoyl carnitine in Caco-2 and IEC-18 cells
article 1998    
Author: Duizer, E. · Wulp, C. van der · Versantvoort, C.H.M. · Groten, J.P.
Keywords: Nutrition · Lactate dehydrogenase · Palmitoylcarnitine · Propidium iodide · Apical membrane · Cell membrane · Cell strain caco 2 · Cell viability · Controlled study · Drug absorption · Drug cytotoxicity · Drug transport · Electric resistance · Human · Human cell · Image processing · Intestine absorption · Macromolecule · Oral drug administration · Priority journal · Protein localization · Tight junction · Animals · Biological Transport · Caco-2 Cells · Cell Survival · Dose-Response Relationship, Drug · Egtazic Acid · Electric Impedance · Humans · Immunohistochemistry · Intestinal Absorption · Membrane Proteins · Octoxynol · Palmitoylcarnitine · Phosphoproteins · Rats · Tight Junctions
[Abstract]

9 Influence of the H-ras oncogene on radiation responses of a rat rhabdomyosarcoma cell line
article 1992    
Author: Hermens, A.F. · Bentvelzen, P.A.J.
Keywords: animal cell · animal model · animal tissue · cell culture · cell killing · cell survival · cell viability · controlled study · dose response · gastrocnemius muscle · genetic transfection · human · human cell · irradiation · nonhuman · oncogene h ras · priority journal · radiation dose fractionation · radiation injury repair · radiation response · radiosensitivity · tumor growth · 3T3 Cells · Animal · Cell Division · Cell Line · Cell Survival · Cesium Radioisotopes · Dose-Response Relationship, Radiation · Gamma Rays · Genes, ras · Human · Mice · Radiation Tolerance · Rats · Rhabdomyosarcoma · Sarcoma, Experimental · Transfection
[Abstract]

10 Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds
article 2010    
Author: Briel, R.J. van de · Pennings, J.L.A. · Baken, K.A. · Pronk, T.E. · Boorsma, A. · Gottschalk, R. · Loveren, H. van
Keywords: Biology · Biomedical Research · Gene profiling · HaCaT · Irritant oxidative stress · Keratinocytes · Sensitizer · 1 chloro 2,4 dinitrobenzene · 2 propanol · benzoic acid · cinnamyl alcohol · collagen type 16 · disulfiram · dodecyl sulfate sodium · eugenol · ferritin · ferrochelatase · glucose 6 phosphate dehydrogenase · glucuronosyltransferase 1A6 · glutamate cysteine ligase · glutathione reductase · heat shock protein · heme oxygenase 1 · hexane · interleukin 6 receptor · irritant agent · isoeugenol · lactic acid · mitogen activated protein kinase · nickel sulfate · phosphogluconate dehydrogenase · salicylic acid methyl ester · thioredoxin 2 · thioredoxin reductase 1 · thioredoxin reductase 2 · transcription factor Nrf2 · article · cell viability · gene control · gene expression profiling · human · human cell · human cell culture · in vitro study · keratinocyte · oxidative stress · random forest · sensitization · support vector machine
[Abstract]

11 Monounsaturated and Saturated, but Not n-6 Polyunsaturated Fatty Acids Decrease Cartilage Destruction under Inflammatory Conditions: A Preliminary Study
article 2013    
Author: Bastiaansen-Jenniskens, Y.M. · Siawash, M. · Lest, C.H.A. van de · Verhaar, J.A.N. · Kloppenburg, M. · Zuurmond, A.M. · Stojanovic-Susulic, V. · Osch, G.J.V.M. van · Clockaerts, S.
Keywords: Health · Cartilage · Chondrocyte · Fatty acids · Collagenase 3 · Disintegrin · Glyceraldehyde 3 phosphate dehydrogenase · Glycosaminoglycan · Interstitial collagenase · Lactate dehydrogenase · Linoleic acid · Monounsaturated fatty acid · Oleic acid · Palmitic acid · Polyunsaturated fatty acid · Prostaglandin E2 · Prostaglandin synthase · Saturated fatty acid · Tumor necrosis factor alpha · Adult · Aged · Cartilage cell · Cartilage degeneration · Cell viability · Controlled study · Cytotoxicity · Enzyme release · Gene expression · Human · Human cell · Human tissue · Immunoassay · Inflammation · Limit of quantitation · Lipid transport · Reverse transcription polymerase chain reaction · Total knee replacement · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

12 Fiber-chimeric adenoviruses expressing fibers from serotype 16 and 50 improve gene transfer to human pancreatic adenocarcinoma
article 2009    
Author: Kuhlmann, K.F.D. · Geer, M.A. van · Bakker, C.T. · Dekker, J.E.M. · Havenga, M.J.E. · Oude Elferink, R.P.J. · Gouma, D.J. · Bosma, P.J. · Wesseling, J.G.
Keywords: Biology · Biomedical Research · Adenovirus · Fiber-chimeric · Pancreatic cancer · Serotype · adenovirus vector · bacterial enzyme · coxsackie virus and adenovirus receptor · cytosine deaminase · flucytosine · green fluorescent protein · red fluorescent protein · virus DNA · virus fiber protein · Adenovirus fiber gene · Adenovirus fiber knob 5 · Adenovirus type 16 · Adenovirus type 50 · antineoplastic activity · article · bacterial gene · cancer cell culture · cell viability · controlled study · cytosine deaminase gene · drug cytotoxicity · drug efficacy · drug mechanism · drug specificity · fiber chimeric human adenovirus 5 · gene directed enzyme prodrug therapy · gene expression · gene targeting · human · Human adenovirus · Human adenovirus 5 · human cell · human tissue · liver cell culture · molecular cloning · nonhuman · pancreas adenocarcinoma · priority journal · protein domain · protein expression · suicide gene · viral gene delivery system · virus fiber · virus gene · Adenoviridae · Cell Line · Cell Line, Tumor · Flow Cytometry · Gene Therapy · Genetic Vectors · Green Fluorescent Proteins · Humans · Pancreatic Neoplasms · Polymerase Chain Reaction · Recombinant Fusion Proteins · Recombination, Genetic · Transduction, Genetic · Viral Envelope Proteins · Adenoviridae
[Abstract]

13 Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat
article 2007    
Author: Hendriksen, P.J.M. · Freidig, A.P. · Jonker, D. · Thissen, U. · Bogaards, J.J.P. · Mumtaz, M.M. · Groten, J.P. · Stierum, R.H.
Keywords: Biology · Analytical research · Biomedical research · Benzene · Mercury · Microarrays · Mixtures · Toxicogenomics · Trichloroethylene · benzene · biological marker · messenger RNA · methylmercury · trichloroethylene · animal experiment · animal tissue · apoptosis · article · Ccng1 gene · cell proliferation · cell viability · controlled study · gene · gene expression profiling · gene induction · id2 gene · liver toxicity · long term exposure · male · MDM2 gene · microarray analysis · nephrotoxicity · NFKB1 gene · nonhuman · Nr2f6 gene · rat · stress · tissue specificity · tnfrsf1a gene · toxicogenetics · transcriptomics · Animals · Benzene · Cell Survival · Drug Interactions · Drug Synergism · Environmental Pollutants · Gene Expression Profiling · Gene Expression Regulation · Kidney · Liver · Male · Methylmercury Compounds · No-Observed-Adverse-Effect Level · Oligonucleotide Array Sequence Analysis · Rats · Rats, Inbred F344 · RNA, Messenger · Toxicity Tests · Trichloroethylene · Rattus
[Abstract]

14 Human apolipoprotein C-I expression in mice impairs learning and memory functions
article 2008    
Author: Abildayeva, K. · Berbée, J.F.P. · Blokland, A. · Jansen, P.J. · Hoek, F.J. · Meijer, O. · Lütjohann, D. · Gautier, T. · Pillot, T. · Vente, J.de · Havekes, L.M. · Ramaekers, F.C.S. · Kuipers, F. · Rensen, P.C.N. · Mulder, M.
Keywords: Health · Physiological Sciences · β-amyloid · Alzheimer's disease · Apolipoprotein E · Morris water maze task · Object recognition task · amyloid beta protein · apolipoprotein E · campesterol · cholestanol · cholesterol · cholesterol derivative · desmosterol · lanosterol · lathosterol · lysophosphatidylcholine · lysophosphatidylethanolamine · messenger RNA · phosphatidylcholine · phosphatidylethanolamine · phosphatidylinositol · phosphatidylserine · sitosterol · sphingomyelin · unclassified drug · animal cell · animal experiment · animal model · animal tissue · apoptosis · astrocyte · brain level · cell viability · controlled study · disease exacerbation · endothelium cell · female · hippocampus · human tissue · learning disorder · lipid metabolism · maze test · memory disorder · mouse · nerve cell necrosis · nonhuman · protein aggregation · protein expression · recognition · task performance · transgenic mouse · wild type · animal · C57BL mouse · gene expression regulation · genetics · metabolism · Animals · Apolipoprotein C-I · Gene Expression Regulation · Humans · Immunohistochemistry · Learning · Memory · Mice · Mice, Inbred C57BL · Mice, Transgenic · RNA, Messenger · Tissue Culture Techniques
[PDF] [Abstract]

15 QSAR models for predicting in vivo aquatic toxicity of chlorinated alkanes to fish
article 2008    
Author: Zvinavashe, E. · Berg, H. van den · Soffers, A.E.M.F. · Vervoort, J. · Freidig, A. · Murk, A.J. · Rietjens, I.M.C.M.
Keywords: Physiological Sciences · 1 chloro 2 methylbutane · 1 chloro 2,2 dimethylpropane · 1 chlorodecane · 1 chlorododecane · 1 chloroheptane · 1 chlorohexane · 1 chlorononane · 1 chlorooctane · 1 chloropentane · 1,1 dichloro 3,3 dimethylbutane · 1,1,2 trichloroethane · 1,10 dichlorodecane · 1,2 dichlorobutane · 1,2 dichloropropane · 1,3 dichloropropane · 1,6 dichlorohexane · 1,8 dichlorooctane · 1,9 dichlorononane · alkane derivative · carbon · carbon tetrachloride · chlorine · tetrachloroethane · animal cell · animal experiment · aquatic environment · article · cell viability · chlorination · CHO cell · controlled study · cytotoxicity · fish · hydrophobicity · nonhuman · quantitative structure activity relation · Algorithms · Animals · Artificial Intelligence · Cell Survival · Chemistry, Physical · CHO Cells · Cricetinae · Cricetulus · Fishes · Hydrocarbons, Chlorinated · Predictive Value of Tests · Quantitative Structure-Activity Relationship · Tetrazolium Salts · Thiazoles · Animalia · Cricetulus griseus
[Abstract]

16 Transcriptional activity around bacterial cell death reveals molecular biomarkers for cell viability
article 2008    
Author: Kort, R. · Keijser, B.J. · Caspers, M.P.M. · Schuren, F.H. · Montijn, R.
Keywords: Biology · Biotechnology · Bacterial RNA · Ribosome RNA · Biological marker · Article · Bacillus subtilis · Bacterial cell · Bacterial growth · Bacterial membrane · Bacterial reproduction · Cell culture · Cell death · Cell viability · Cellular stress response · Controlled study · Cytology · Gene cluster · Gene expression · Genetic transcription · Growth curve · Heat stress · Nonhuman · Protein folding · RNA stability · Sporogenesis · Transcription regulation · Bacterial count · DNA microarray · Gene expression profiling · Gene expression regulation · Genetics · Growth, development and aging · Heat · Heat shock response · Microbial viability · Multigene family · Physiology · Transcription initiation · Bacillus subtilis · Bacteria (microorganisms) · Posibacteria · Bacillus subtilis · Biological Markers · Colony Count, Microbial · Gene Expression Profiling · Gene Expression Regulation, Bacterial · Heat-Shock Response · Hot Temperature · Microbial Viability · Multigene Family · Oligonucleotide Array Sequence Analysis · RNA Stability · RNA, Bacterial · Transcription, Genetic · Transcriptional Activation
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date