Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 14 of 14 found. | Sort by date

1 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

2 Personalised nutrition: Status and perspectives
article 2007    
Author: Joost, H.G. · Gibney, M.J. · Cashman, K.D. · Görman, U. · Hesketh, J.E. · Mueller, M. · Ommen, B. van · Williams, C.M. · Mathers, J.C.
Keywords: Biomedical Research · Disease risk · Nutrigenetics · Nutrigenomics · Nutritional recommendations · Acyltransferase · Glutathione transferase · Xenobiotic agent · Carcinogenesis · Cholesterol metabolism · Diabetes mellitus · Dietary intake · Environmental factor · Familial hyperlipemia · Food composition · Gene interaction · Gene mutation · Genetic counseling · Genetic heterogeneity · Genetic screening · Genetic variability · Genotype phenotype correlation · Hypercholesterolemia · Hypertension · Mental deficiency · Nonhuman · Nutrient supply · Nutrigenomics · Nutritional assessment · Nutritional status · Nutritional value · Risk benefit analysis · Risk factor · Risk reduction · Single nucleotide polymorphism · Chronic Disease · Food · Genotype · Humans · Models, Genetic · Nutrition Disorders · Nutrition Physiology · Nutritional Requirements · Research
[PDF] [Abstract]

3 Cholestrol content of the rat lens is lowered by administration of simvastatin, but not pravastatin
article 1993    
Author: Vries, A.C.J. de · Vermeer, M.A. · Bredman, J.J. · Bar, P.R. · Cohen, L.H.
Keywords: Pharmacology · 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors · hypocholesterolaemic drugs · antilipemic agent · drug derivative · hydroxymethylglutaryl coenzyme A reductase inhibitor · hypocholesterolemic agent · mevinolin · animal experiment · cholesterol metabolism · oral drug administration · biosynthesis · dose response · drug effect · enzymology · liver microsome · metabolism · organ culture · rat strain · time · Aging · Animal · Anticholesteremic Agents · Antilipemic Agents · Cholesterol · Dose-Response Relationship, Drug · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lens, Crystalline · Lovastatin · Microsomes, Liver · Organ Culture · Pravastatin · Rats · Rats, Wistar · Simvastatin · Time Factors
[Abstract]

4 LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus
article 2007    
Author: Mulder, M. · Koopmans, G. · Wassink, G. · Mansouri, G.A. · Simard, M.-L. · Havekes, L.M. · Prickaerts, J. · Blokland, A.
Keywords: Health · Biomedical Research · Apolipoprotein E · Cholesterol · Low density lipoprotein receptor · Memory · Neurogenesis · Synaptic density · apolipoprotein E · broxuridine · cholesterol · iodine 125 · low density lipoprotein · low density lipoprotein receptor · synaptophysin · Alzheimer disease · animal cell · animal experiment · animal tissue · article · astrocytoma cell · cell proliferation · cholesterol metabolism · concentration response · controlled study · dentate gyrus · hippocampus · knockout mouse · male · memory · mouse · nerve cell plasticity · nerve fiber growth · nervous system development · neuroblastoma cell · nonhuman · pathogenesis · priority journal · spatial memory · synaptogenesis · wild type · Animals · Biological Markers · Bromodeoxyuridine · Cell Count · Cell Line, Tumor · Cell Proliferation · Cholesterol · Dentate Gyrus · Down-Regulation · Hippocampus · Humans · Male · Mice · Mice, Knockout · Neural Pathways · Neuronal Plasticity · Presynaptic Terminals · Receptors, LDL · Synaptophysin
[Abstract]

5 Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
article 2015    
Author: Berbeé, J.F.P. · Boon, M.R. · Khedoe, P.P.S.J. · Bartelt, A. · Schlein, C. · Worthmann, A. · Kooijman, S. · Hoeke, G. · Mol, I.M. · John, C. · Jung, C. · Vazirpanah, N. · Brouwers, L.P.J. · Gordts, P.L.S.M. · Esko, J.D. · Hiemstra, P.S. · Havekes, L.M. · Scheja, L. · Heeren, J. · Rensen, P.C.N.
Keywords: Biology · 5 [2 [[2 (3 chlorophenyl) 2 hydroxyethyl]amino]propyl] 1,3 benzodioxole 2,2 dicarboxylic acid · Apolipoprotein E · Cholesterol · Fatty acid · Low density lipoprotein receptor · Triacylglycerol · Bioenergetics · Fat · Fatty acid · Obesity · Plasma · Rodent · Animal experiment · Animal model · Animal tissue · Atherosclerosis · Beta adrenergic stimulation · Brown adipose tissue · Cholesterol blood level · Cholesterol metabolism · Controlled study · Energy expenditure · Fatty acid transport · Female · Hypercholesterolemia · Lipolysis · Liver clearance · Mouse · Triacylglycerol blood level · Mus · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

6 Bromobenzene-induced hepatotoxicity at the transcriptome level
article 2004    
Author: Heijne, W.H.M. · Slitt, A.L. · Bladeren, P.J. van · Groten, J.P. · Klaassen, C.D. · Stierum, R.H. · Ommen, B. van
Keywords: Biology Toxicology · Physiological Sciences · Bromobenzene · cDNA microarray · Hepatotoxicity · Rat · Toxicogenomics · Transcriptomics · Bromobenzene · Cholesterol · Complementary DNA · Cytochrome P450 4A · Fatty acid · Glutathione · Messenger RNA · Metallothionein · Protein · Sterol · Acute phase response · Animal experiment · Animal model · Animal tissue · Cell communication · Cholesterol metabolism · Concentration response · Controlled study · Cytoskeleton · DNA determination · DNA microarray · DNA responsive element · Drug metabolism · Electron · Fatty acid metabolism · Gene amplification · Gene expression profiling · Gene rearrangement · Liver toxicity · Nonhuman · Nucleotide sequence · Oxidative stress · Protein depletion · Protein metabolism · Protein synthesis · Rat · Signal transduction · Transcription regulation · Animals · Bromobenzenes · Gene Expression Profiling · Gene Expression Regulation · Glutathione · Hepatitis, Toxic · Liver · Male · Microarray Analysis · Oligonucleotide Array Sequence Analysis · Rats · Rats, Inbred Strains · Time Factors · Transcription, Genetic
[Abstract]

7 Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure
article 2005    
Author: Heijne, W.H.M. · Jonker, D. · Stierum, R.H. · Ommen, B. van · Groten, J.P.
Keywords: Toxicology Biology · Toxicology and Applied Pharmacology · Benzene · cDNA microarrays · Gene expression · Hepatotoxicity · Metabolomics · Toxicogenomics · Transcriptomics · benzene · bromobenzene · paracetamol · animal experiment · animal tissue · biotransformation · blood toxicity · cholesterol metabolism · conference paper · DNA microarray · gene expression · genetic analysis · genetic toxicology · glutathione metabolism · liver necrosis · liver weight · male · nonhuman · nuclear magnetic resonance spectroscopy · nucleotide sequence · priority journal · rat · rat strain · unindexed sequence · Animals · Benzene · Blood Cell Count · Cholesterol · Fatty Acids · Gene Expression Profiling · Gene Expression Regulation · Hemoglobins · Liver · Male · Mutagens · Oligonucleotide Array Sequence Analysis · Organ Size · Rats · Rats, Inbred F344 · Spleen · Thymus Gland · Time Factors · Urinalysis · Martes pennanti
[Abstract]

8 Cholesterol 7α-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol
article 2006    
Author: Post, S.M. · Groenendijk, M. · Hoogt, C.C. van der · Fievet, C. · Luc, G. · Hoekstra, M. · Princen, H.M.G. · Staels, B. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · High-density lipoprotein · ABC transporter A1 · High density lipoprotein cholesterol · Intermediate density lipoprotein · Low density lipoprotein · Messenger RNA · Phosphatidylcholine sterol acyltransferase · Very low density lipoprotein · Bile acid · Phospholipid transfer protein · Phospholipid transfer protein, mouse · Animal experiment · Animal tissue · Bile acid synthesis · Biosynthesis · Catabolism · Cholesterol blood level · Cholesterol metabolism · cholesterol transport · Conhuman · Protein expression · Transgenic mouse · Genetics · Metabolism · Mouse · Mouse mutant · Physiology · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol, HDL · Female · Gene Expression Regulation · Gene Expression Regulation, Enzymologic · Humans · Liver · Mice · Mice, Knockout · Mice, Transgenic · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipid Transfer Proteins · RNA, Messenger
[Abstract]

9 Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis
article 2017    
Author: Hoeke, G. · Wang, Y. · Dam, A.D. van · Mol, M. · Gart, E. · Klop, H.G. · Berg, S.M. van den · Pieterman, E.H. · Princen, H.M.G. · Groen, A.K. · Rensen, P.C.N. · Berbée, J.F.P. · Boon, M.R.
Keywords: Biology · Atherosclerosis · Brown adipose tissue · Hypercholesterolemia · Cholesterol metabolism · Lipid and lipoprotein metabolism · 5 [2 [[2 (3 chlorophenyl) 2 hydroxyethyl]amino]propyl] 1,3 benzodioxole 2,2 dicarboxylic acid · Atorvastatin · Cholesterol · Fatty acid · High density lipoprotein cholesterol · Lipoprotein · Proprotein convertase 9 · Triacylglycerol · Animal experiment · Animal model · Animal tissue · Atherosclerosis · Brown adipose tissue · Cholesterol blood level · Controlled study · Drug effect · Drug potentiation · Energy expenditure · Female · Gene expression · Hypercholesterolemia · Lipid composition · Lipid liver level · Lipid metabolism · Lipid oxidation · Lipid transport · Lipoprotein metabolism · Mouse · Nonhuman · Triacylglycerol blood level · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

10 Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
article 1995    
Author: Twisk, J. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · cholic acid · deoxycholic acid · lithocholic acid · messenger rna · oxygenase · sterol · taurocholic acid · animal cell · article · bile acid synthesis · cholesterol metabolism · controlled study · enzyme inhibition · gene repression · liver cell culture · nonhuman · priority journal · rat · transcription regulation · Adenosine Triphosphate · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Down-Regulation · Gene Expression Regulation, Enzymologic · Liver · Male · Mitochondria · Oxidoreductases · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

11 The association of 83 plasma proteins with CHD mortality, BMI, HDL-, and total-cholesterol in men: Applying multivariate statistics to identify proteins with prognostic value and biological relevance
article 2009    
Author: Geert Heidema, A. · Thissen, U. · Boer, J.M.A. · Bouwman, F.G. · Feskens, E.J.M. · Mariman, E.C.M.
Keywords: Biology Health Nutrition · Analytical research · BMI · CHD · HDL-cholesterol · Partial least squares · Proteomics · alpha 2 macroglobulin · apolipoprotein A1 · beta 2 microglobulin · C reactive protein · CD40 antigen · cholesterol · fibrinogen · growth hormone · high density lipoprotein cholesterol · immunoglobulin M · insulin · leptin · macrophage derived chemokine · macrophage inflammatory protein 1beta · matrix metalloproteinase · plasma protein · plasminogen activator inhibitor 1 · pregnancy associated plasma protein A · tissue inhibitor of metalloproteinase 1 · vascular cell adhesion molecule 1 · vasculotropin · adult · angiogenesis · article · blood clotting · body mass · cardiovascular disease · case control study · cholesterol blood level · cholesterol metabolism · clinical article · controlled study · disease association · enzyme activity · follow up · human · immune response · immunoassay · inflammation · ischemic heart disease · lipid metabolism · male · mortality · multivariate analysis · Netherlands · partial least squares regression · principal component analysis · priority journal · prognosis · protein analysis · proteomics · risk factor · statistical analysis · univariate analysis
[Abstract]

12 No effects of atorvastatin (10 mg/d or 80 mg/d) on nitric oxide, prostacyclin, thromboxane and oxidative stress in type 2 diabetes mellitus patients of the DALI study
article 2015    
Author: Tsikas, D. · Pham, V.V. · Suchy, M.T. · Ree, M.A. van de · Huisman, M.V. · Frölich, J.C. · Princen, H.M.G.
Keywords: Biology · 8-iso-Prostaglandin F2α · Carbonic anhydrase · Cardiovascular disease · Diabetes mellitus type 2 · Nitric oxide · Oxidative stress · Prostacyclin · Statins · Thromboxane · 2,3 dinor 6 oxoprostaglandin F1 alpha · 2,3 dinorthromboxane B2 · 8 isoprostaglandin F2 alpha · Atorvastatin · Carbonate dehydratase · Cholesterol · Nitrate · Nitric oxide · Nitrite · Placebo · Prostacyclin · Prostaglandin synthase · Thromboxane · Thromboxane A2 · Adult · Aged · Antioxidant activity · Biosynthesis · Cholesterol metabolism · Controlled study · Dose response · Double blind procedure · Drug effect · Drug treatment failure · Dyslipidemia · Female · Heart protection · Lipid peroxidation · Lipolysis · Major clinical study · Male · Mass fragmentography · Middle aged · Non insulin dependent diabetes mellitus · Oxidative stress · Randomized controlled trial · Tandem mass spectrometry · Treatment duration · Urine level · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

13 Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice
article 2006    
Author: Duivenvoorden, I. · Voshol, P.J. · Rensen, P.C.N. · Duyvenvoorde, W. van · Romijn, J.A. · Emeis, J.J. · Havekes, L.M. · Nieuwenhuizen, W.F.
Keywords: Health Biology · Food technology · APOE*3Leiden mice · Cholesterol · Free fatty acids · Sphingolipids · Steatosis · Triacylglycerol · alanine aminotransferase · amyloid · apolipoprotein E3 · cholesterol · cholesterol ester · fatty acid · messenger RNA · phytosphingosine · RNA · sphingolipid · triacylglycerol · apolipoprotein E · apolipoprotein E3 (Leidein) · very low density lipoprotein · animal experiment · animal model · animal tissue · article · cholesterol blood level · cholesterol metabolism · controlled study · diet supplementation · dose response · drug effect · drug structure · fatty liver · female · gene expression · hepatitis · lipogenesis · lipolysis · mouse · nonhuman · nutritional assessment · plasma clearance · prophylaxis · animal · blood · chemistry · cholesterol intake · enzymology · feces · genetics · intestine absorption · lipid metabolism · liver · metabolism · physiology · randomization · transgenic mouse · Animals · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Cholesterol, Dietary · Dose-Response Relationship, Drug · Fatty Acids, Nonesterified · Fatty Liver · Feces · Female · Gene Expression · Intestinal Absorption · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Random Allocation · RNA · Sphingolipids · Triglycerides
[Abstract]

14 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 14 of 14 found. | Sort by date