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1 Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans
article 1988    
Author: Kempen, H.J.M. · Glatz, J.F.C. · Gevers Leuven, J.A. · Voort, H.A. van der · Katan, M.B.
Keywords: Biology · Fatty acid · Hydroxymethylglutaryl coenzyme a reductase · Lanosterol · Lathosterol · Simvastatin · Cholesterol synthesis · Clinical article · Diet · Familial hypercholesterolemia · Human cell · Normal human · Serum · Anticholesteremic Agents · Biological Markers · Cholesterol · Female · Human · Hypercholesterolemia, Familial · Isomerism · Lovastatin · Male · Simvastatin
[PDF] [Abstract]

2 Bile acids and lipids in isolated rat hepatocytes. II. Source of cholesterol used for bile acid formation, estimated by incorporation of tritium from tritiated water, and by the effect of ML-236B
article 1983    
Author: Kempen, H.J. · Vos Van Holstein, M. · Lange, J.de
Keywords: Biology · Bile acid · Cholic acid · Compactin · Ml 236 b · Radioisotope · Tritium oxide · Unclassified drug · Animal cell · Beta muricholic acid · Cholesterol c 14 · Cholesterol h 3 · Cholesterol synthesis · Dihydroxycholanoic acid · In vitro study · Liver cell · Muricholic acid · Nonhuman · Taurocholic acid c 14 · Animal · Bile Acids and Salts · Cholesterol · Cholestyramine · Lipids · Liver · Naphthalenes · Rats · Tritium
[PDF] [Abstract]

3 Vastatins have a distinct effect on sterol synthesis and progesterone secretion in human granulosa cells in vitro
article 1996    
Author: Vliet, A.K. van · Thiel, G.C.F. van · Naaktgeboren, N. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitor · Progesterone secretion · Simvastatin · Sterol synthesis · Cholesterol · Low density lipoprotein · Methysticin · Cholesterol synthesis · Controlled study · Human cell · Cells, Cultured · Cholesterol · Culture Media · Enzyme Inhibitors · Female · Follicle Stimulating Hormone · Granulosa Cells · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Luteinizing Hormone · Pravastatin · Progesterone · Simvastatin
[Abstract]

4 Different effects of the hypolipidemic drugs pravastatin and lovastatin on the cholesterol biosynthesis of the human ocular lens in organ culture and on the cholesterol content of the rat lens in vivo
article 1993    
Author: Vries, A.C.J. de · Cohen, L.H.
Keywords: Health · HMG-CoA reductase inhibitor · Ocular lens · Pravastatin · Vastatin · hydroxymethylglutaryl coenzyme a reductase · mevinolin · animal experiment · cholesterol synthesis · human tissue · lens · Adult · Aged · Animal · Cholesterol · Comparative Study · Fatty Acids · Human · Lens, Crystalline · Lovastatin · Middle Age · Organ Culture · Pravastatin · Rats · Rats, Wistar · Animalia · Rattus norvegicus
[Abstract]

5 Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations
article 2014    
Author: Pas, N.C.A. van de · Rullmann, J.A.C. · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · Cholesterol · LDL · PBK modeling · Personalized medicine · Statin response · Virtual subjects · cholesterol · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Low density lipoprotein receptor · Pravastatin · Very low density lipoprotein cholesterol · Cholesterol blood level · Cholesterol synthesis · Drug effect · Drug mechanism · Human · Kinetics · Major clinical study · Monte Carlo method · Physiologically based kinetic · Protein expression · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

6 Anacetrapib reduces (V)LDL-cholesterol by inhibition of CETP activity and reduction of plasma PCSK9
article 2015    
Author: Tuin, S.J. van der · Kühnast, S. · Berbée, J. · Verschuren, L. · Pieterman, E.J. · Havekes, L.M. · Hoorn, J.W. van der · Rensen, P.C. · Jukema, J.W. · Princen, H.M. · Willems van Dijk, K. · Wang, Y.
Keywords: Health · CETP · Cholesterol · Metabolism · Drug therapy · Hypolipidemic drugs · LDL · Metabolism · Lipids · Lipoproteins · PCSK9 · Anacetrapib · Apolipoprotein B · Cholesterol ester transfer protein · Low density lipoprotein receptor · Proprotein convertase subtilisin kexin type 9 · RNA · Serine proteinase · Sterol regulatory element binding protein 1 · Sterol regulatory element binding protein 2 · Triacylglycerol · Unclassified drug · Very low density lipoprotein cholesterol · Animal experiment · Animal tissue · Atherosclerosis · Cholesterol synthesis · Controlled study · Down regulation · Drug mechanism · Enzyme blood level · Female · Liver · Microarray analysis · Mouse · Nonhuman · Polymerase chain reaction · Protein expression · RNA isolation · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

7 Rosuvastatin reduces plasma lipids by inhibiting VLDL production and enhancing hepatobiliary lipid excretion in ApoE*3-Leiden mice
article 2005    
Author: Delsing, D.J.M. · Post, S.M. · Groenendijk, M. · Solaas, K. · Boom, H. van der · Duyvenvoorde, W. van · Wit, E.C.M. de · Bloks, V.W. · Kuipers, F. · Havekes, L.M. · Princen, H.M.G.
Keywords: Biomedical Research · Gene expression · Lipid metabolism · Lipoproteins · Statin · diacylglycerol acyltransferase · hydroxymethylglutaryl coenzyme A reductase inhibitor · mevinolin · phospholipid · rosuvastatin · very low density lipoprotein · animal tissue · biliary excretion · cholesterol blood level · cholesterol diet · cholesterol synthesis · controlled study · enzyme activity · gene expression · hepatobiliary system · lipid blood level · lipid composition · lipid diet · lipid liver level · lipolysis · mouse · nonhuman · priority journal · rat · statistical significance · triacylglycerol blood level · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile · Bile Acids and Salts · Cholesterol · Cholesterol, VLDL · Chromatography, High Pressure Liquid · Feces · Female · Fluorobenzenes · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Liver · Mice · Mice, Transgenic · Pyrimidines · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Sterols · Sulfonamides · Triglycerides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date