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Showing 1 to 17 of 17 found. | Sort by date

1 Atypical xanthomatosis in apolipoprotein E-deficient mice after cholesterol feeding
article 1995    
Author: Ree, J.H. van · Gijbels, M.J.J. · Broek, W.J.A.A. van den · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Cholesterol deposition · Familial dysbetalipoproteinemia · Gene targeting · Hypercholesterolemia · Lipoprotein metabolism · Mouse model · apolipoprotein e · cholesterol · animal experiment · animal model · article · cholesterol diet · familial hypercholesterolemia · gene targeting · histology · hyperlipoproteinemia type 3 · lipoprotein metabolism · mouse · nonhuman · priority journal · xanthomatosis · Animal · Apolipoproteins E · Cholesterol, Dietary · Human · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Support, Non-U.S. Gov't · Xanthomatosis
[Abstract]

2 Effects of dietary fish oil on serum lipids and VLDL kinetics in hyperlipidemic apolipoprotein E*3-Leiden transgenic mice
article 1998    
Author: Vlijmen, B.J.M. van · Mensink, R.P. · Hof, H.B. van 't · Offermans, R.F.G. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Dietary fish oil · Hypertipidemia · n-3 fatty acids · Transgenic mice · VLDL metabolism · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Cholesterol · Cholesterol, Dietary · Dietary Fats · Female · Fish Oils · Humans · Hyperlipidemias · Kinetics · Lipoproteins · Lipoproteins, HDL · Lipoproteins, IDL · Lipoproteins, LDL · Lipoproteins, VLDL · Mice · Mice, Transgenic · Triglycerides
[PDF] [Abstract]

3 Both lipolysis and hepatic uptake of VLDL are impaired in transgenic mice coexpressing human apolipoprotein E*3Leiden and human apolipoprotein C1
article 1996    
Author: Jong, M.C. · Dahlmans, V.E.H. · Gorp, P.J.J. van · Breuer, M.L. · Mol, M.J.T.M. · Zee, A. van der · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Transgenic mice · Triacylglycerol · Very low density lipoprotein · Animal experiment · Animal model · Atherosclerosis · Cholesterol blood level · Controlled study · Female · Lipolysis · Liver clearance · Liver metabolism · Male · Nonhuman · Protein transport · Transgenic mouse · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Cholesterol, Dietary · Gene Expression · Humans · Hyperlipoproteinemias · Lipolysis · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Triglycerides
[Abstract]

4 Differences between men and women in the response of serum cholesterol to dietary changes
article 1999    
Author: Weggemans, R.M. · Zock, P.L. · Urgert, R. · Katan, M.B.
Keywords: Nutrition · Cholesterol · Diet · Gender · Lipids · Lipoproteins · Responsiveness · Cafestol · Saturated fatty acid · Adult · Cholesterol blood level · Cholesterol intake · Clinical trial · Diet therapy · Fat intake · Female · Human · Hypercholesterolemia · Major clinical study · Male · Meta analysis · Priority journal · Sex difference · Body Mass Index · Cholesterol · Cholesterol, Dietary · Cholesterol, HDL · Cholesterol, LDL · Clinical Trials · Coffee · Confidence Intervals · Dietary Fats · Diterpenes · Female · Humans · Male · Middle Aged · Sex Characteristics
[Abstract]

5 Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice : An immunohistochemical study
article 1999    
Author: Gijbels, M.J.J. · Cammen, M. van der · Laan, L.J.W. van der · Emeis, J.J. · Havekes, L.M. · Hofker, M.H. · Kraal, G.
Keywords: Biology · Atherosclerosis · Immunohistochemistry · Progression · Regression · Transgenic mice · Animals · Antibodies, Monoclonal · Antigens, CD4 · Aorta · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Cell Adhesion Molecules · Cholesterol · Cholesterol, Dietary · Disease Progression · Endothelium, Vascular · Female · Immunohistochemistry · Intercellular Adhesion Molecule-1 · Macrophages · Membrane Glycoproteins · Mice · Mice, Transgenic · Receptors, Immunologic · Receptors, Scavenger · T-Lymphocytes · Triglycerides
[Abstract]

6 Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein C1-deficient mice
article 1997    
Author: Jong, M.C. · Ree, J.H. van · Dahlmans, V.E.H. · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · very low density lipoprotein · animal experiment · catabolism · controlled study · human · hyperlipoproteinemia · lipolysis · metabolism · mouse · nonhuman · priority journal · protein degradation · protein metabolism · transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins B · Apolipoproteins C · Cholesterol, Dietary · Female · Lipolysis · Lipoproteins, VLDL · Mice · Mice, Mutant Strains · Triglycerides · Ultracentrifugation · Animalia · Mus musculus
[Abstract]

7 Accelerated atherosclerosis by placement of a perivascular cuff and a cholesterol-rich diet in ApoE*3Leiden transgenic mice
article 2000    
Author: Lardenoye, J.H.P. · Delsing, D.J.M. · Vries, M.R. de · Deckers, M.M.L. · Princen, H.M.G. · Havekes, L.M. · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Animals · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Cholesterol · Cholesterol, Dietary · Constriction · Diet, Atherogenic · Femoral Artery · Genetic Predisposition to Disease · Hemorheology · Hypercholesterolemia · Hyperplasia · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Point Mutation · Specific Pathogen-Free Organisms · Triglycerides · Tunica Intima
[Abstract]

8 Differential effects of amlodipine and atorvastatin treatment and their combination on atherosclerosis in ApoE*3-Leiden transgenic mice
article 2003    
Author: Delsing, D.J.M. · Jukema, J.W. · Wiel, M.A. van de · Emeis, J.J. · Laarse, A. van der · Havekes, L.M. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Atherosclerosis · Calcification · Calcium antagonists · Inflammation · Statins · Amlodipine · Atorvastatin · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Very low density lipoprotein cholesterol · Animal model · Animal tissue · Aorta root · Cholesterol blood level · Cholesterol diet · Controlled study · Drug effect · Inflammation · Mouse · Nonhuman · Amlodipine · Animals · Aorta, Thoracic · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Blood Pressure · Calcium Channel Blockers · Cholesterol · Cholesterol, Dietary · Drug Therapy, Combination · Female · Heptanoic Acids · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Mice · Mice, Transgenic · Pyrroles
[Abstract]

9 Quantitative assessment of aortic atherosclerosis in APOE*3 leiden transgenic mice and its relationship to serum cholesterol exposure
article 1996    
Author: Groot, P.H.E. · Vlijmen, B.J.M. van · Benson, G.M. · Hofker, M.H. · Schiffelers, R. · Vidgeon-Hart, M. · Havekes, L.M.
Keywords: Biology · animal model · apolipoprotein E · diet · familial dyslipoproteinemia · hyperlipidemia · apolipoprotein e · cholesterol · animal experiment · animal model · animal tissue · aorta atherosclerosis · aorta sinus · article · atherosclerosis · cholesterol blood level · cholesterol diet · controlled study · dyslipoproteinemia · feeding · female · hyperlipidemia · hypolipemia · lipid diet · male · mouse · nonhuman · priority journal · transgenic mouse · Animals · Aortic Diseases · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Cholesterol · Cholesterol, Dietary · Dietary Fats · Female · Hyperlipidemias · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Sinus of Valsalva
[Abstract]

10 Oxidation of LDL and extent of peripheral atherosclerosis
article 1999    
Author: Vijver, L.P.L. van de · Kardinaal, A.F.M. · Duyvenvoorde, W. van · Kruijssen, D.A.C.M. · Grobbee, D.E. · Poppel, G. van · Princen, H.M.G.
Keywords: Biology · Ankle-arm index · LDL composition · LDL oxidation · Peripheral atherosclerosis · Resistance time · Acetylsalicylic acid · Antihypertensive agent · Copper · Coumarin derivative · High density lipoprotein cholesterol · Low density lipoprotein · Low density lipoprotein cholesterol · Triacylglycerol · Adult · Aged · Arm · Atherosclerosis · Cholesterol blood level · Diet · Disease severity · Drug use · Human · Leg · Aged · Aged, 80 and over · Anticoagulants · Antihypertensive Agents · Arteriosclerosis · Aspirin · Cholesterol, Dietary · Coumarins · Diet, Fat-Restricted · Humans · Lipid Peroxidation · Lipoproteins, LDL · Male · Middle Aged · Odds Ratio · Risk Factors
[Abstract]

11 Effect of partially hydrolyzed guar gum (PHGG) on the bioaccessibility of fat and cholesterol
article 2005    
Author: Minekus, M. · Jelier, M. · Xiao, J.-Z. · Kondo, S. · Iwatsuki, K. · Kokubo, S. · Bos, M. · Dunnewind, B. · Havenaar, R.
Keywords: Health · Biomedical Research · Bioaccessibility · Cholesterol · Depletion flocculation · Dietary fiber · Fat · Absorption · Biochemistry · Cholesterol · Emulsification · Flocculation · Hydrolysis · Lipids · Oils and fats · Bioaccessibility · Flocculation mechanism · Gastrointestinal tracts · Partially hydrolyzed guar gum (PHGG) · Organic compounds · galactan · guar gum · mannan · pepsin A · plant gum · sunflower oil · vegetable oil · yoghurt · article · bile · biological model · chemistry · cholesterol intake · drug effect · fat intake · hydrolysis · intestine absorption · micelle · nutritional value · pH · time · Bile · Cholesterol, Dietary · Dietary Fats · Galactans · Hydrogen-Ion Concentration · Hydrolysis · Intestinal Absorption · Mannans · Micelles · Models, Biological · Nutritive Value · Pepsin A · Plant Gums · Plant Oils · Time Factors · Yogurt · Cyamopsis tetragonoloba · Helianthus
[Abstract]

12 Increased response to cholesterol feeding in apolipoprotein C1-deficient mice
article 1995    
Author: Ree, J.H. van · Hofker, M.H. · Broek, J.A.A. van den · Deursen, J.M.A. van · Boom, H. van der · Frants, R.R. · Wieringa, B. · Havekes, L.M.
Keywords: Biology · apolipoprotein c1 · apolipoprotein e · very low density lipoprotein · animal cell · animal experiment · animal model · article · cholesterol blood level · cholesterol intake · controlled study · embryo · female · gene targeting · hep 2 cell · homozygosity · hypercholesterolemia · lipoprotein deficiency · lipoprotein metabolism · mouse · mutant · nonhuman · priority journal · stem cell · triacylglycerol blood level · Animal · Apolipoproteins C · Cholesterol · Cholesterol, Dietary · Gene Targeting · Heterozygote · Homozygote · Lipoproteins, HDL Cholesterol · Lipoproteins, LDL Cholesterol · Lipoproteins, VLDL Cholesterol · Mice · Mice, Inbred C57BL · Mice, Inbred CBA · Mice, Transgenic · Mutation · Receptors, LDL · Support, Non-U.S. Gov't · Triglycerides
[Abstract]

13 Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice
article 2006    
Author: Duivenvoorden, I. · Voshol, P.J. · Rensen, P.C.N. · Duyvenvoorde, W. van · Romijn, J.A. · Emeis, J.J. · Havekes, L.M. · Nieuwenhuizen, W.F.
Keywords: Health Biology · Food technology · APOE*3Leiden mice · Cholesterol · Free fatty acids · Sphingolipids · Steatosis · Triacylglycerol · alanine aminotransferase · amyloid · apolipoprotein E3 · cholesterol · cholesterol ester · fatty acid · messenger RNA · phytosphingosine · RNA · sphingolipid · triacylglycerol · apolipoprotein E · apolipoprotein E3 (Leidein) · very low density lipoprotein · animal experiment · animal model · animal tissue · article · cholesterol blood level · cholesterol metabolism · controlled study · diet supplementation · dose response · drug effect · drug structure · fatty liver · female · gene expression · hepatitis · lipogenesis · lipolysis · mouse · nonhuman · nutritional assessment · plasma clearance · prophylaxis · animal · blood · chemistry · cholesterol intake · enzymology · feces · genetics · intestine absorption · lipid metabolism · liver · metabolism · physiology · randomization · transgenic mouse · Animals · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Cholesterol, Dietary · Dose-Response Relationship, Drug · Fatty Acids, Nonesterified · Fatty Liver · Feces · Female · Gene Expression · Intestinal Absorption · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Random Allocation · RNA · Sphingolipids · Triglycerides
[Abstract]

14 Atorvastatin increases HDL cholesterol by reducing CETP expression in cholesterol-fed APOE*3-Leiden.CETP mice
article 2008    
Author: Haan, W. de · Hoogt, C.C. van der · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Princen, H.M.G. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · CETP · High-density lipoprotein · HMGCoA reductase · Statin · Transgenic mice · ABC transporter A1 · apolipoprotein A1 · apolipoprotein E3 · atorvastatin · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · messenger RNA · phospholipid transfer protein · scavenger receptor BI · very low density lipoprotein · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · cholesterol diet · controlled study · drug effect · gene expression · hypercholesterolemia · lipoprotein blood level · lipoprotein metabolism · male · mouse · nonhuman · priority journal · protein expression · transgenic mouse · Animals · Apolipoprotein E3 · Cholesterol Ester Transfer Proteins · Cholesterol, Dietary · Cholesterol, HDL · Cholesterol, VLDL · Dose-Response Relationship, Drug · Female · Gene Expression · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypercholesterolemia · Liver · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Pyrroles · RNA, Messenger
[Abstract]

15 Dual PPARα/γ agonist tesaglitazar reduces atherosclerosis in insulin-resistant and hypercholesterolemic ApoE*3Leiden mice
article 2006    
Author: Zadelaar, A.S.M. · Boesten, L.S.M. · Jukema, J.W. · Vlijmen, B.J.M. van · Kooistra, T. · Emeis, J.J. · Lundholm, E. · Camejo, G. · Havekes, L.M.
Keywords: Cholesterol · Inhibitors · Collagen · Immunoglobulin enhancer binding protein · Serum amyloid A · Tesaglitazar · 2 ethoxy 3 (4 ((4 (methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid · Alkanesulfonic acid · Apolipoprotein E3 (Leidein) · Biological marker · Lipoprotein · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor gamma · Phenylpropionic acid derivative · Animal cell · Animal experiment · Animal model · Animal tissue · Blood vessel wall · Cholesterol blood level · Controlled study · Diet · Enzyme activity · Monocyte · Mouse · Nonhuman · Protein blood level · Transgenic mouse · Blood · Cholesterol intake · Drug potentiation · Fat intake · Metabolism · Pathology · Pathophysiology · Alkanesulfonates · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Biological Markers · Blood Vessels · Cell Adhesion · Cholesterol · Cholesterol, Dietary · Collagen · Dietary Fats · Female · Hypercholesterolemia · Inflammation · Insulin Resistance · Lipids · Lipoproteins · Macrophages · Mice · Mice, Transgenic · Monocytes · NF-kappa B · Phenylpropionates · PPAR alpha · PPAR gamma
[Abstract]

16 Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: A combined transcriptomics and metabolomics analysis
article 2007    
Author: Kleemann, R. · Verschuren, L. · Erk, M.J. van · Nikolsky, Y. · Cnubben, N.H.P. · Verheij, E.R. · Smilde, A.K. · Hendriks, H.F.J. · Zadelaar, A.S.M. · Smith, G.J. · Kaznacheev, V. · Nikolskaya, T. · Melnikov, A. · Hurt-Camejo, E. · Greef, J. van der · Ommen, B. van · Kooistra, T.
Keywords: Analytical research · Biomedical research · alanine aminotransferase · aspartate aminotransferase · cholesterol · endothelial leukocyte adhesion molecule 1 · gamma interferon · high density lipoprotein · hydroxymethylglutaryl coenzyme A reductase · immunoglobulin enhancer binding protein · interleukin 1 · low density lipoprotein · peroxisome proliferator activated receptor alpha · platelet derived growth factor · protein p53 · retinoid X receptor · retinoid X receptor alpha · serum amyloid A · Smad3 protein · STAT1 protein · STAT3 protein · STAT5 protein · sterol regulatory element binding protein 1 · sterol regulatory element binding protein 2 · transcription factor FKHR · transcription factor Sp1 · transcription factor YY1 · triacylglycerol · tumor necrosis factor alpha · very low density lipoprotein · alanine aminotransferase blood level · animal experiment · animal model · animal tissue · article · aspartate aminotransferase blood level · atherosclerosis · cholesterol blood level · cholesterol diet · cholesterol intake · controlled study · diet supplementation · female · gene control · genetic transcription · hepatitis · hypercholesterolemia · lipid metabolism · metabolomics · mouse · nonhuman · pathophysiology · protein blood level · stress · transcription regulation · transcriptomics · triacylglycerol blood level · upregulation · animal · biological model · diet · disease model · gene expression regulation · inflammation · liver · metabolism · pathology · systems biology · Mus · Animals · Atherosclerosis · Cholesterol, Dietary · Diet · Disease Models, Animal · Female · Gene Expression Regulation · Inflammation · Lipid Metabolism · Liver · Metabolism · Mice · Models, Biological · Systems Biology · Transcription, Genetic
[Abstract]

17 Quantitative profiling of bile acids in biofluids and tissues based on accurate mass high resolution LC-FT-MS: Compound class targeting in a metabolomics workflow
article 2008    
Author: Bobeldijk, I. · Hekman, M. · Vries de- Weij, J.van der · Coulier, L. · Ramaker, R. · Kleemann, R. · Kooistra, T. · Rubingh, C. · Freidig, A. · Verheij, E.
Keywords: Analytical research · Accurate mass · Bile acids · Body fluids · High performance liquid chromatography · Metabolomics · Targeted metabolite profiling · Tissues · Acids · Arsenic compounds · Chlorine compounds · Cholesterol · Chromatographic analysis · Complexation · Electrospray ionization · Fourier transforms · High performance liquid chromatography · Histology · Ionization · Ionization of liquids · Liquid chromatography · Liquid phase epitaxy · Liver · Mass spectrometers · Mass spectrometry · Metabolites · Phase separation · Plasmas · Separation · Spectrometers · Spectrometry · Sulfate minerals · Accurate mass · Bile acid synthesis · Bile acids · Bio-fluids · Biological fluids · Cholesterol homeostasis · Chromatography-mass spectrometry · Electro spraying · Fourier Transform Mass Spectrometer · Generic methods · High resolutions · HPLC-MS · Human plasmas · Human urine · Linear ion trap · Metabolomics · Mouse liver · Pooled samples · Reversed-phase high performance · Sample preparations · Targeted metabolite profiling · Tissues · Body fluids · Bile acid · Glycine · Sulfate · Accuracy · Animal experiment · Animal tissue · Article · Bile acid synthesis · Body fluid · Cholesterol intake · Cholesterol liver level · Controlled study · Electrospray · Fourier transform mass spectrometry · Homeostasis · Human · Liver · Metabolite · Metabolomics · Nonhuman · Priority journal · Quantitative analysis · Reversed phase high performance liquid chromatography · Statistical significance · Tissue · Animals · Bile Acids and Salts · Cholesterol, Dietary · Chromatography, Liquid · Computational Biology · Fourier Analysis · Humans · Liver · Mass Spectrometry · Metabolism · Mice · Reproducibility of Results
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 17 of 17 found. | Sort by date