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Showing 1 to 18 of 18 found. | Sort by date

1 A novel injectable thermoresponsive and cytocompatible gel of poly(N-isopropylacrylamide) with layered double hydroxides facilitates siRNA delivery into chondrocytes in 3D culture
article 2015    
Author: Yang, H.Y. · Ee, R.J. van · Timmer, K. · Craenmehr, E.G.M. · Huang, J.H. · Öner, C. · Dhert, W.J.A. · Kragten, A.H.M. · Willems, N. · Grinwis, G.C.M. · Tryfonidou, M.A. · Papen-Botterhuis, N.E. · Creemers, L.B.
Keywords: Materials Health · Injectable hydrogel · siRNA delivery · Poly(N-isopropylacrylamide) · Layered double hydroxides · Chondrocytes · Healthy Living · Nano Technology · MAS - Materials Solutions · TS - Technical Sciences
[Abstract]

2 Fibroblast-like synoviocyte-chondrocyte interaction in cartilage degradation
article 2007    
Author: Steenvoorden, M.M.C. · Bank, R.A. · Ronday, H.K. · Toes, R.E.M. · Huizinga, T.W.J. · Groot, J. de
Keywords: Health · Biomedical Research · Alginate recovered chondrocytes · Cartilage · Cartilage degradation · Fibroblast-like synoviocytes · In vitro model · Rheumatoid arthritis · Alginates · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cell Communication · Cells, Cultured · Chondrocytes · Collagen · Disease Models, Animal · Fibroblasts · Glucuronic Acid · Hexuronic Acids · Interleukin-1beta · Osteoarthritis · Proteoglycans · Synovial Membrane · Tumor Necrosis Factor-alpha
[Abstract]

3 Inhibition of glycosaminoglycan incorporation influences collagen network formation during cartilage matrix production
article 2009    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Jansen, K.M.B. · Verhaar, J.A.N. · Groot, J. de · Vanosch, G.J.V.M.
Keywords: Biology · Biomedical Research · Cartilage matrix · Glycosaminoglycan · Cartilage cell · Cartilage degeneration · Cell culture · Concentration response · Cross linking · Alginates · Animals · Cattle · Chondrocytes · Collagen Type II · Gene Expression · Glucuronic Acid · Glycosaminoglycans · Glycosides · Hexuronic Acids · SOX9 Transcription Factor · Tissue Culture Techniques · Bovinae
[Abstract]

4 Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology
article 2007    
Author: Scharstuhl, A. · Schewe, B. · Benz, K. · Gaissmaier, C. · Bühring, H.J. · Stoop, R.
Keywords: Biology · Biomedical Research · Age-related · Chondrogenic differentiation · Differentiation · Etiology · Isolation · Mesenchymal stem cells · Total hip prosthesis · Adult · Adult Stem Cells · Aged · Aged, 80 and over · Aging · Cells, Cultured · Chondrocytes · Humans · Mesenchymal Stem Cells · Middle Aged · Osteoarthritis
[Abstract]

5 The onset of generalized osteoarthritis in older women: A qualitative approach
article 2001    
Author: Okma-Keulen, P. · Hopman-Rock, M.
Keywords: Health · Qualitative · Women · Adult · Clinical article · Depression · Diet · Disease exacerbation · Health status · Heredity · Pain · Stress · Age of Onset · Aged · Chondrocytes · Chronology · Female · Genetic Predisposition to Disease · Humans · Joints · Life Style · Middle Aged · Netherlands · Osteoarthritis · Risk Factors
[Abstract]

6 Accumulation of Advanced Glycation End Products as a Molecular Mechanism for Aging as a Risk Factor in Osteoarthritis
article 2004    
Author: Groot, J. de · Verzijl, N. · Wenting-Wijk, M.J.G. van · Jacobs, K.M.G. · El, B. van · Roermund, P.M. van · Bank, R.A. · Bijlsma, J.W.J. · TeKoppele, J.M. · Lafeber, F.P.J.G.
Keywords: Biology Health · Biomedical Research · Advanced glycation end product · Ribose · Animal experiment · Animal model · Animal tissue · Anterior cruciate ligament · Collagen defect · Controlled study · Disease predisposition · Disease severity · Extracellular matrix · Histopathology · Hypothesis · In vivo study · Nonhuman · Pathogenesis · Aging · Animals · Anterior Cruciate Ligament · Cartilage, Articular · Chondrocytes · Disease Models, Animal · Dogs · Female · Glycosylation End Products, Advanced · Osteoarthritis · Risk Factors
[Abstract]

7 Degeneration, inflammation, regeneration, and pain/disability in dogs following destabilization or articular cartilage grooving of the stifle joint
article 2008    
Author: Frost-Christensen, L.N. · Mastbergen, S.C. · Vianen, M.E. · Hartog, A. · Groot, J. de · Voorhout, G. · Wees, A.M.C. van · Lafeber, F.P.J.G. · Hazewinkel, H.A.W.
Keywords: Health · ACLT · Gait · Groove-model · Meniscectomy · Osteoarthritis · Animal experiment · Animal model · Animal tissue · Anterior cruciate ligament injury · Article · Articular cartilage · Cartilage cell · Controlled study · Disease model · Dog · Gait · Joint degeneration · Knee osteoarthritis · Knee pain · Knee radiography · Nonhuman · Osteophyte · Physical disability · Priority journal · Synovitis · Tissue regeneration · Animals · Anterior Cruciate Ligament · Arthralgia · Cartilage, Articular · Chondrocytes · Dogs · Gait · Inflammation · Joint Instability · Models, Animal · Osteoarthritis · Osteophyte · Regeneration · Stifle
[Abstract]

8 Degenerated and healthy cartilage are equally vulnerable to blood-induced damage
article 2008    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Theobald, M. · Lafeber, F.P.J.G.
Keywords: Health · Matrix metalloproteinase · Proteoglycan · Aged · Article · Blood · Cartilage cell · Cartilage degeneration · Controlled study · Enzyme activity · Female · Hemarthrosis · Human · Human tissue · Male · Osteoarthritis · Priority journal · Proteoglycan synthesis · Aged · Blood · Cartilage, Articular · Chondrocytes · Female · Hemarthrosis · Humans · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis · Proteoglycans · Tissue Culture Techniques · Food and Nutrition · Healthy Living
[Abstract]

9 Doxycycline inhibits collagen synthesis by differentiated articular chondrocytes.
article 1998    
Author: TeKoppele, J.M. · Beekman, B. · Verzijl, N. · Koopman, J.L. · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · antiinfective agent · collagen · doxycycline · metalloproteinase · protein synthesis inhibitor · proteinase inhibitor · animal · article · articular cartilage · biosynthesis · cartilage cell · cattle · cell culture · cytology · dog · drug antagonism · metabolism · osteoarthritis · Animals · Anti-Bacterial Agents · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Dogs · Doxycycline · Metalloendopeptidases · Osteoarthritis · Protease Inhibitors · Protein Synthesis Inhibitors
[Abstract]

10 Matrix degradation by chondrocytes cultured in alginate : IL-1β induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation
article 1998    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M. de · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Matrix degradation · Matrix metalloproteinases · alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid · collagen · glycosaminoglycan · interleukin 1beta · metalloproteinase · proteoglycan · cartilage cell · degradation · enzyme synthesis · extracellular matrix · Alginates · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Interleukin-1 · Metalloendopeptidases · Microspheres · Proteoglycans
[Abstract]

11 Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis
article 2001    
Author: Ronday, H.K. · Laan, W.H. van der · Tak, P.P. · Roos, J.A.D.M. de · Bank, R.A. · Tekoppele, J.M. · Froelich, C.J. · Hack, C.E. · Hogendoorn, P.C.W. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology Health · Biomedical Research · Cartilage destruction · Granzyme B · Rheumatoid arthritis · collagen · glycosaminoglycan · granzyme B · hydroxyproline · proline · proteoglycan · sulfate · sulfur 35 · tritium · animal tissue · bone erosion · cartilage degeneration · cartilage matrix · collagen degradation · controlled study · explant · human cell · immunohistochemistry · isotope labeling · joint destruction · nonhuman · priority journal · protein denaturation · protein expression · proteoglycan synthesis · rheumatoid arthritis · synovium · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Granzymes · Humans · Metacarpophalangeal Joint · Proteoglycans · Serine Endopeptidases · Synovial Membrane
[Abstract]

12 Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes
article 2001    
Author: Groot, J. de · Verzijl, N. · Budde, M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Advanced glycation end product · Alginate culture · Cartilage · Chondrocyte · Collagen · Matrix metalloproteinase · Turnover · advanced glycation end product · alginic acid · collagen · matrix metalloproteinase · ribose · animal cell · article · articular cartilage · cartilage cell · cattle · cell culture · collagen defect · collagen degradation · collagen synthesis · controlled study · culture medium · enzyme activity · extracellular matrix · nonhuman · osteoarthritis · priority journal · reaction time · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Enzyme Precursors · Extracellular Matrix · Glycosylation End Products, Advanced · Matrix Metalloproteinases · Osteoarthritis · Ribose · Bovinae
[Abstract]

13 Contribution of collagen network features to functional properties of engineered cartilage
article 2008    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Linden, J.C. van der · Zuurmond, A.M. · Weinans, H. · Verhaar, J.A.N. · Osch, G.J.V.M. van · Groot, J. de
Keywords: Health · Cartilage · Chondrocyte · Collagen · Crosslinks · Mechanical properties · 3 aminopropionitrile · alginic acid · collagen · interstitial collagenase · water · animal cell · animal cell culture · article · articular cartilage · cartilage cell · cartilage matrix · cattle · collagen degradation · controlled study · cross linking · nonhuman · priority journal · protein degradation · rigidity · tissue engineering · water retention · Alginates · Aminopropionitrile · Animals · Biomechanics · Cartilage, Articular · Cattle · Cell Count · Cells, Cultured · Chondrocytes · Extracellular Matrix · Fibrillar Collagens · Gene Expression · Matrix Metalloproteinases · Osteoarthritis · Permeability · Phenotype · Regeneration · Stress, Mechanical · Time Factors · Tissue Engineering
[Abstract]

14 Effect of collagen turnover on the accumulation of advanced glycation end products
article 2000    
Author: Verzijl, N. · Groot, J. de · Thorpe, S.R. · Bank, R.A. · Shaw, J.N. · Lyons, T.J. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · Baynes, J.W. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · Advanced glycation end product · Aspartic acid · Collagen · N (carboxyethyl)lysine · N (carboxymethyl)lysine · Pentosidine · Unclassified drug · Age · Articular cartilage · Cell survival · Controlled study · Glycation · Human · Human cell · Human tissue · Kinetics · Priority journal · Protein metabolism · Skin · Turnover time · Adolescent · Adult · Age Factors · Aged · Aged, 80 and over · Arginine · Aspartic Acid · Cartilage, Articular · Child · Child, Preschool · Chondrocytes · Collagen · Glycosylation End Products, Advanced · Humans · Kinetics · Lysine · Middle Aged · Skin
[PDF] [Abstract]

15 The canine 'groove' model, compared with the ACLT model of osteoarthritis
article 2002    
Author: Marijnissen, A.C.A. · Roermund, P.M. van · TeKoppele, J.M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Canine model · Cartilage · Osteoarthritis · Proteoglycans · collagen · collagenase 3 · interstitial collagenase · matrix protein · proteoglycan · stromelysin · animal experiment · animal model · animal tissue · anterior cruciate ligament · article · articular cartilage · biochemistry · cartilage cell · cartilage degeneration · collagen degradation · controlled study · disease model · disease severity · dog · enzyme activity · evaluation · female · femur condyle · histopathology · joint stability · knee · nonhuman · osteoarthritis · priority journal · protein depletion · synovial fluid · synovitis · tissue injury · weight bearing · Animals · Cartilage, Articular · Chondrocytes · Collagen · Collagenases · Dogs · Female · Matrix Metalloproteinase 1 · Matrix Metalloproteinase 13 · Matrix Metalloproteinase 3 · Models, Animal · Osteoarthritis · Proteoglycans · Synovial Fluid · Weight-Bearing
[Abstract]

16 Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice
article 2006    
Author: Valverde-Franco, G. · Binette, J.S. · Li, W. · Wang, H. · Chai, S. · Laflamme, F. · Tran-Khanh, N. · Quenneville, E. · Meijers, T. · Poole, A.R. · Mort, J.S. · Buschmann, M.D. · Henderson, J.E.
Keywords: Collagenase 3 · Core protein · Epitope · Fibroblast growth factor receptor 3 · Proteoglycan · Animal cell · Animal experiment · Animal model · Animal tissue · Cartilage degeneration · Cartilage matrix · Cell structure · Compression · Controlled study · Genetic procedures · Humerus head · Hypertrophy · Immunoreactivity · Mouse · Nonhuman · Physical resistance · Protein deficiency · Protein degradation · Protein expression · Protein targeting · Rigidity · Signal transduction · Synovium · Tissue metabolism · Aggrecans · Animals · Arthritis · Cartilage · Cartilage Diseases · Cartilage, Articular · Chondrocytes · Collagen Type II · Collagen Type X · Collagenases · Crosses, Genetic · Epitopes · Extracellular Matrix Proteins · Lectins, C-Type · Matrix Metalloproteinase 13 · Mice · Mice, Transgenic · Osteoblasts · Proteochondroitin Sulfates · Receptor, Fibroblast Growth Factor, Type 3 · Signal Transduction
[Abstract]

17 Biochemical and functional modulation of the cartilage collagen network by IGF1, TGFβ2 and FGF2
article 2006    
Author: Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Weinans, H. · Jahr, H. · Verhaar, J.A.N. · Groot, J. de · Osch, G.J.V.M. van
Keywords: Biology · Biomedical Research · Chondrocyte · Cross-links · Growth factors · Mechanical properties · Proteoglycans · Alginic acid · Collagen fiber · Fibroblast growth factor 2 · Matrix metalloproteinase · Proteoglycan · Pyridinoline · Somatomedin C · Transforming growth factor beta2 · Animal cell · Animal tissue · Cartilage cell · Cartilage matrix · Collagen synthesis · Controlled study · Cow · Culture medium · Enzyme activity · Enzyme analysis · Nonhuman · Permeability · Protein cross linking · Protein determination · Protein function · Protein protein interaction · Rigidity · Aggrecans · Animals · Biomechanics · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Collagen Type II · DNA · Extracellular Matrix · Fibroblast Growth Factor 2 · Forelimb · Gene Expression · Immunohistochemistry · Insulin-Like Growth Factor I · Matrix Metalloproteinases · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein-Lysine 6-Oxidase · Proteoglycans · Transforming Growth Factor beta2
[Abstract]

18 TGFβ affects collagen cross-linking independent of chondrocyte phenotype but strongly depending on physical environment
article 2008    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Zuurmond, A.-M. · Bank, R.A. · Verhaar, J.A.N. · Groot, J. de · Osch, G.J.V.M. van
Keywords: Biology · Alginate · Body fluids · Cell proliferation · Cells · Cobalt · Cobalt compounds · Collagen · Colloids · Electron energy levels · Fibroblasts · Gelation · Matrix algebra · Painting · Photoacoustic effect · Shape memory effect · Technology · Tissue · Tissue culture · Tissue engineering · Alginate gel (AG) · Cartilage tissue engineering · Cell populations · Chondrocyte · Chondrocytes · Collagen cross-linking · Collagen deposition · Cultures (Traditional) · Matrix formation · Mechanical stressing · Monolayer cultures · Physical environments · Primary cells · Shape memory alloy (SMA) fibers · Smooth muscle actin (SMA) · Tissue culture plastic (TCP) · Transforming Growth Factor (TGF) · Cell culture · Alginic acid · Alpha smooth muscle actin · Collagen · Transforming growth factor beta · Actin · Collagen type 1 · Collagen type 2 · Cross linking reagent · DNA · Transcription factor Sox9 · Transforming growth factor beta2 · Animal cell · Animal tissue · Article · Calf (bovine) · Cartilage cell · Cell population · Controlled study · Cross linking · Drug effect · Fibroblast · Nonhuman · Phenotype · Priority journal · Upregulation · Animal · Cattle · Cell culture · Cytology · Extracellular matrix · Gene expression regulation · Genetics · Immunohistochemistry · Metabolism · Smooth muscle · Actins · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Collagen Type I · Collagen Type II · Cross-Linking Reagents · DNA · Extracellular Matrix · Gene Expression Regulation · Immunohistochemistry · Muscle, Smooth · Phenotype · SOX9 Transcription Factor · Transforming Growth Factor beta2
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date