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Showing 1 to 8 of 8 found. | Sort by date

1 Effects of iron salts and haemosiderin from a thalassaemia patient on oxygen radical damage as measured in the comet assay
article 2000    
Author: Anderson, D. · Yardley-Jones, A. · Hambly, R.J. · Vives-Bauza, C. · Smykatz-Kloss, V. · Chua-anusorn, W. · Webb, J.
Keywords: Chelating agents · Free radical damage · Haemoglobin synthesis · Haemosiderin · Iron overload · Thalassaemia · chelating agent · deferoxamine · ferric chloride · ferrous chloride · ferrous sulfate · free radical · hemosiderin · hydrogen peroxide · iron chelate · iron salt · oxygen radical · article · case report · cell strain CACO 2 · comet assay · controlled study · DNA damage · DNA strand breakage · female · human · human cell · human experiment · human tissue · iron overload · lymphocyte · male · normal human · oxidative stress · priority journal · thalassemia · Caco-2 Cells · Comet Assay · DNA Damage · Dose-Response Relationship, Drug · Female · Ferric Compounds · Ferrous Compounds · Hemosiderin · Humans · Hydrogen Peroxide · Iron Compounds · Lymphocytes · Male · Reactive Oxygen Species · Thalassemia · Production · Technology · Food · Salt
[Abstract]

2 Genotoxicity and mutagenicity
article 2005    
Author: Maurici, D. · Aardema, M. · Corvi, R. · Kleber, M. · Krul, C.A.M. · Laurent, C. · Loprieno, N. · Pasanen, M. · Pfuhler, S. · Phillips, B. · Sabbioni, E. · Sanner, T. · Vanparys, P.
Keywords: Toxicology · Physiological sciences · Animal testing replacement · Animal testing alternatives · Chromosome aberration · Comet assay · DNA damage · DNA synthesis · Gene mutation · Genotoxicity · In vitro study · In vivo study · Micronucleus test · Mitotic recombination · Mutagenicity · Sister chromatid exchange · Toxicity testing · Toxicogenetics · Toxicokinetics · Toxicological parameters · Carcinogen testing · Cell culture · Chemistry · Legal aspects · Structure activity relation · Animalia · Consumer product safety · Cosmetics · European Union · Structure-Activity Relationship

3 Effects of vitamin C supplementation in human volunteers with a range of cholesterol levels on biomarkers of oxygen radical-generated damage
article 2000    
Author: Anderson, D. · Phillips, B.J. · Yu, T-W. · Edwards, A.J. · Ayesh, R. · Butterworth, K.R.
Keywords: Medicine · Geneeskunde · Health · Gezondheid · Dietetics · Voedingsleer · ascorbic acid · biological marker · bleomycin · cholesterol · horlicks · oxygen radical · placebo · protein p21 · Ras protein · sanatogen · adult · aged · antioxidant activity · cholesterol blood level · chromosome aberration · clinical trial · comet assay · conference paper · controlled clinical trial · controlled study · crossover procedure · DNA damage · dose response · female · human · human experiment · lipid peroxidation · lymphocyte · male · normal human · oxidative stress · priority journal · sex difference · vitamin blood level · vitamin supplementation
[Abstract]

4 Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility
article 2018    
Author: Reisinger, K. · Blatz, V. · Brinkmann, J. · Downs, T.R. · Fischer, A. · Henkler, F. · Hoffmann, S. · Krul, C. · Liebsch, M. · Luch, A. · Pirow, R. · Reus, A.A. · Schulz, M. · Pfuhler, S.
Keywords: Biology · Comet assay · Dermal exposure · DNA damage · In vitro genotoxicity · Phenion®FT · Skin · 7,12 dimethylbenz[a]anthracene · Aphidicolin · Cadmium chloride · Cyclohexanone · Ethylnitrosourea · Fallic acid propyl ester · Mitomycin · Phthalic acid bis(2 ethylhexyl) ester · Cell isolation · Controlled study · Cytotoxicity test · Genotoxicity assay · Human · Human tissue · Predictive value · Priority journal · Reproducibility · Validation study · Biomedical Innovation · Healthy Living · Life Triskelion BV · RAPID - Risk Analysis for Products in Development TARA - Toxicology and Risk Assessment · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

5 UV-induced effects
article 2005    
Author: Liebsch, M. · Spielmann, H. · Pape, W. · Krul, C. · Deguercy, A. · Eskes, C.A.M.
Keywords: Health · Physiological Sciences · cosmetic · hypoxanthine phosphoribosyltransferase · acute toxicity · allergenicity · animal testing replacement · cell line · chromosome aberration · comet assay · DNA damage · gene mutation · genotoxicity · human · in vivo study · micronucleus · model · nonhuman · photosensitization · phototoxicity · point mutation · priority journal · radiation exposure · radiation hazard · review · standardization · ultraviolet A radiation · ultraviolet radiation · validation process · Animal Testing Alternatives · Animals · Cell Line · Consumer Product Safety · Cosmetics · Dermatitis, Photoallergic · Dermatitis, Phototoxic · DNA · DNA Damage · Drug Stability · Erythrocytes · European Union · Hemolysis · Humans · Mutagenicity Tests · Mutagens · Photosensitizing Agents · Skin · Skin Irritancy Tests · Ultraviolet Rays · Animalia
[Abstract]

6 Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic polymorphisms for GSTM1 GSTT1
article 2001    
Author: Delft, J.H.M. van · Steenwinkel, M.-J.S.T. · Asten, J.G. van · Vogel, N. de · Bruijntjes-Rozier, T.C.D.M. · Schouten, T. · Cramers, P. · Maas, L. · Herwijnen, M.H. van · Schooten, F.-J. van · Hopmans, P.M.J.
Keywords: Biology · 1-OHpyr: 1-hydroxypyrene · GST: glutathione S-transferase · HFC: cells with a high frequency of SCE · MN: micronuclei · PAH: polycyclic aromatic hydrocarbons · SCE: sister-chromatid exchange · 1 Hydroxypyrene · Glutathione transferase · Polycyclic aromatic hydrocarbon · Adult · Biological monitoring · Cancer risk · Chromosome analysis · Coke oven industry · Comet assay · Controlled study · DNA adduct · DNA strand breakage · Endothelium cell · Genetic polymorphism · Human · Industrial worker · Industry · Lung cancer · Lymphocyte · Male · Micronucleus test · Multivariate analysis · Normal human · Occupational exposure · Priority journal · Sister chromatid exchange · Smoking · Urine level · Adult · Coke · DNA Adducts · Glutathione Transferase · Humans · Middle Aged · Multivariate Analysis · Occupational Exposure · Polycyclic Hydrocarbons, Aromatic · Polymorphism, Genetic · Sister Chromatid Exchange · Smoking
[Abstract]

7 IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans
article 2000    
Author: Albertini, R.J. · Anderson, D. · Douglas, G.R. · Hagmar, L. · Hemminki, K. · Merlo, F. · Natarajan, A.T. · Norppa, H. · Shuker, D.E.G. · Tice, R. · Waters, M.D. · Aitio, A.
Keywords: Biomarkers · Biomonitoring · Genotoxic carcinogens · Guideline · Human populations · WHO · carcinogen · hypoxanthine phosphoribosyltransferase · blood analysis · carcinogenicity · chromosome aberration · comet assay · cytogenetics · DNA adduct · DNA damage · ethics · fluorescence in situ hybridization · gene mutation · genotoxicity · human · micronucleus test · patient monitoring · practice guideline · priority journal · protein binding · review · risk assessment · sampling · sister chromatid exchange · statistical analysis · technique · Carcinogens · Chromosome Aberrations · DNA Damage · Environmental Health · Environmental Monitoring · Humans · Hypoxanthine Phosphoribosyltransferase · In Situ Hybridization, Fluorescence · International Cooperation · Lymphocytes · Micronucleus Tests · Mutagens · Sister Chromatid Exchange · Toxicity Tests · United Nations · World Health Organization
[Abstract]

8 Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers
article 2003    
Author: Rhodes, L.E. · Shahbakhti, H. · Azurdia, R.M. · Moison, R.M.W. · Steenwinkel, M.J.S.T. · Homburg, M.I. · Dean, M.P. · McArdle, F. · Beijersbergen van Henegouwen, G.M.J. · Epe, B. · Vink, A.A.
Keywords: Health Nutrition · Physiological Sciences · 8 hydroxydeoxyguanosine · alpha tocopherol · antioxidant · ascorbic acid · glutathione · icosapentaenoic acid · monounsaturated fatty acid · oleic acid · omega 3 fatty acid · protein p53 · adult · aged · cancer risk · clinical trial · comet assay · controlled clinical trial · controlled study · DNA damage · DNA strand breakage · dose response · double blind procedure · drug bioavailability · drug structure · drug tissue level · epidermis cell · erythema · female · flatulence · genotoxicity · human · human experiment · human tissue · immunohistochemistry · lipid peroxidation · male · normal human · oxidative stress · peripheral lymphocyte · photooxidation · photosensitivity · priority journal · protein expression · randomized controlled trial · review · skin cancer · skin carcinogenesis · sunburn · ultraviolet radiation · Adult · Aged · Ascorbic Acid · Biological Availability · Dietary Supplements · DNA · DNA Damage · DNA Repair · Double-Blind Method · Eicosapentaenoic Acid · Female · Genetic Markers · Glutathione · Humans · Lipid Peroxidation · Lymphocytes · Male · Middle Aged · Neoplasms, Radiation-Induced · Oleic Acid · Skin · Skin Neoplasms · Tumor Suppressor Protein p53 · Ultraviolet Rays · Vitamin E
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date