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1 Screening and characterization of Lactobacillus strains producing large amounts of exopolysaccharides
article 1998    
Author: Geel-Schutten, G.H. van · Flesch, F. · Brink, B. ten · Smith, M.R. · Dijkhuizen, L.
Keywords: Nutrition · Fructan · Polysaccharide · Raffinose · Sucrose · Bacterial metabolism · Carbohydrate synthesis · Concentration response · Lactobacillus reuteri · Nonhuman · Strain difference · Lactobacillus reuteri
[Abstract]

2 Effects of chlorpyrifos on individuals and populations of Daphnia pulex in the laboratory and field
article 1997    
Author: Hoeven, N. van der · Gerritsen, A.A.M.
Keywords: Environment · Age · Enclosure · Insecticide · Recovery · Chlorpyrifos · Animal cell · Concentration response · Controlled study · Daphnia · Nonhuman · Pest control · Population dynamics · Population risk · Prediction · Priority journal · Species difference
[Abstract]

3 Inhibition of glycosaminoglycan incorporation influences collagen network formation during cartilage matrix production
article 2009    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Jansen, K.M.B. · Verhaar, J.A.N. · Groot, J. de · Vanosch, G.J.V.M.
Keywords: Biology · Biomedical Research · Cartilage matrix · Glycosaminoglycan · Cartilage cell · Cartilage degeneration · Cell culture · Concentration response · Cross linking · Alginates · Animals · Cattle · Chondrocytes · Collagen Type II · Gene Expression · Glucuronic Acid · Glycosaminoglycans · Glycosides · Hexuronic Acids · SOX9 Transcription Factor · Tissue Culture Techniques · Bovinae
[Abstract]

4 A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo
article 2009    
Author: Kienhuis, A.S. · Poll, M.C.G. van de · Jong, C.H.C. de · Gottschalk, R. · Herwijnen, M. van · Boorsma, A. · Kleinjans, J.C.S. · Stierum, R.H. · Delft, J.H.M. van
Keywords: Biology · Biomedical Research · Coumarin · Gene expression profiling · Hepatotoxicity · Parallelogram approach · Primary human hepatocytes · Species difference · Toxicogenomics · Coumarin · Adult · Aged · Blood clotting · Concentration response · Controlled study · Disorders of mitochondrial functions · Down regulation · Energy consumption · Female · Gene expression profiling · Genomics · Human · Human cell · Liver cell · Liver toxicity · Male · Species difference · Toxicogenetics · Transcriptomics · Animalia · Rattus
[Abstract]

5 Behavioural effects and kinetics in brain in response to inhalation of constant or fluctuating toluene concentrations in the rat
article 2005    
Author: Lammers, J.H.C.M. · Asperen, J. van · Groot, D. de · Rijcken, W.R.P.
Keywords: Health Biology · Toxicology and Applied Pharmacology · Motor activity · Peak exposure · Rat · Toluene · Toxicokinetics · Visual discrimination · toluene · animal experiment · animal model · blood level · brain level · concentration response · conference paper · controlled study · exposure · male · motor activity · neurotoxicity · nonhuman · priority journal · rat · toxicokinetics · visual discrimination
[Abstract]

6 Characterization of Pea Vicilin. 2. Consequences of Compositional Heterogeneity on Heat-Induced Gelation Behavior
article 2004    
Author: O'Kane, F.E. · Happe, R.P. · Vereijken, J.M. · Gruppen, H. · Boekel, M.A.J.S. van
Keywords: Nutrition · Food technology · Aggregation · Gelation · Heterogeneity · N-terminal extension region · Pisum · Storage proteins · Turbid and transparent gels · vicilin · Alpha chain · Amino terminal sequence · Concentration response · Gelation · Heat · Hydrophobicity · Nonhuman · Pea · PH · Protein analysis · Protein folding · Turbidity · Gels · Heat · Hydrogen-Ion Concentration · Peas · Plant Proteins · Protein Folding · Sodium Chloride · Pisum · Pisum sativum
[Abstract]

7 Toxicokinetics and metabolism
article 2005    
Author: Coecke, S. · Blaauboer, B.J. · Elaut, G. · Freeman, S. · Freidig, A. · Gensmantel, N. · Hoet, P. · Kapoulas, V.M. · Ladstetter, B. · Langley, G. · Leahy, D. · Mannens, G. · Meneguz, A. · Monshouwer, M. · Nemery, B. · Pelkonen, O. · Pfaller, W. · Prieto, P. · Proctor, N. · Rogiers, V. · Rostami-Hodjegan, A. · Sabbioni, E. · Steiling, W. · Sandt, J.J.M. van de
Keywords: Toxicology · Food and Chemical Risk Analysis · cosmetic · acute toxicity · artificial membrane · bioavailability · biotransformation · carcinogenicity · cell line · cell strain CACO 2 · computer model · concentration response · electric resistance · eye irritation · genotoxicity · human · metabolism · nonhuman · phototoxicity · plasma protein binding · practice guideline · priority journal · reproductive toxicity · review · skin absorption · skin sensitization · species difference · toxicokinetics · validation process · Animals · Biotransformation · Consumer Product Safety · Cosmetics · Drug Administration Routes · European Union · Humans

8 Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin
article 2003    
Author: Zanden, J.J. van · Hamman, O.B. · Iersel, M.L.P.S. van · Boeren, S. · Cnubben, N.H.P. · Lo Bello, M. · Vervoort, J. · Bladeren, P.J. van · Rietjens, I.M.C.M.
Keywords: Biology · Physiological Sciences · Cysteine · Glutathione S-transferase · Inhibition · Quercetin · Quinone · ascorbic acid · cysteine · flavonoid · glutathione · glutathione transferase · isoenzyme · mutant protein · quercetin · article · chemical interaction · concentration response · covalent bond · dimerization · enzyme inhibition · human · incubation time · inhibition kinetics · time · Chromatography, High Pressure Liquid · Dose-Response Relationship, Drug · Glutathione Transferase · Humans · Mass Spectrometry · Molecular Structure · Monophenol Monooxygenase · Mutation · Quercetin
[Abstract]

9 Respiratory irritation by trimellitic anhydride in Brown Norway and Wistar rats
article 2001    
Author: Arts, J.H.E. · Koning, M.W.de · Bloksma, N. · Kuper, C.F.
Keywords: trimellitic anhydride · animal experiment · article · breathing pattern · concentration response · controlled study · female · lung function · lung weight · nonhuman · priority journal · rat · rat strain · respiratory tract allergy · statistical analysis · Administration, Inhalation · Algorithms · Anhydrides · Animals · Female · Immunoglobulin E · Irritants · Lung · Metals · Organ Size · Particle Size · Rats · Rats, Inbred BN · Rats, Wistar · Respiratory Function Tests · Respiratory Tract Diseases · Animalia · Rattus norvegicus
[Abstract]

10 Time course of peritoneal tissue plasminogen activator after experimental colonic surgery: Effect of hyaluronan-based antiadhesive agents and bacterial peritonitis
article 2002    
Author: Reijnen, M.M.P.J. · Holmdahl, L. · Kooistra, T. · Falk, P. · Hendriks, T. · Goor, H. van
Keywords: Adhesive agent · Hyaluronic acid · Abdominal infection · Animal tissue · Bacterial peritonitis · Biopsy · Colon anastomosis · Colon surgery · Concentration response · Controlled study · Disease severity · Drug effect · Enzyme activity · Fibrinolysis · Male · Measurement · Nonhuman · Time · Adhesions · Animals · Bacterial Infections · Colon · Hyaluronic Acid · Male · Peritoneum · Peritonitis · Rats · Rats, Wistar · Tissue Plasminogen Activator
[Abstract]

11 Influence of dietary components associated with high or low risk of colon cancer on apoptosis in the rat colon
article 2002    
Author: Hambly, R.J. · Saunders, M. · Rijken, P.J. · Rowland, I.R.
Keywords: Nutrition · Apoptosis · Colon cancer · 1,2 dimethylhydrazine · Calcium · Carbohydrate · Fat · Animal experiment · Animal tissue · Cancer risk · Carbohydrate diet · Colon carcinogenesis · Colon carcinoma · Concentration response · Controlled study · Diet · High risk population · Low fat diet · Nonhuman · Animals · Apoptosis · Body Weight · Colon · Colonic Neoplasms · Diet · DNA · Rats · Rats, Sprague-Dawley · Risk Factors
[Abstract]

12 Genetic and reproductive toxicity of butadiene and isoprene
article 2001    
Author: Anderson, D.
Keywords: Nutrition · Cytogenetic effects · Isoprene · Somatic and germ cells · 1,2 epoxy 3 butene · 1,3 butadiene · butadiene diepoxide · cytochrome P450 · hypoxanthine phosphoribosyltransferase · alkalinity · biological monitoring · carcinogenesis · CHO cell · chromosome aberration · comparative study · concentration response · conference paper · cytogenetics · Drosophila melanogaster · exposure · gene translocation · genotoxicity · lethal mutant · liver metabolism · mutagenicity · nonhuman · reproductive toxicity · Salmonella typhimurium · Testis · Animalia · Drosophila melanogaster · Melanogaster · Salmonella typhimurium · Typhimurium · Cytogenetic effects · Isoprene · Somatic and germ cells · 1,2 epoxy 3 butene · 1,3 butadiene · butadiene diepoxide · cytochrome P450 · hypoxanthine phosphoribosyltransferase · alkalinity · biological monitoring · carcinogenesis · CHO cell · chromosome aberration · comparative study · concentration response · conference paper · cytogenetics · Drosophila melanogaster · exposure · gene translocation · genotoxicity · lethal mutant · liver metabolism · mutagenicity · nonhuman · reproductive toxicity · Salmonella typhimurium · sister chromatid exchange · spermatozoon motility · tissue distribution · Animals · Butadienes · Female · Hemiterpenes · Humans · Male · Mice · Mutagenicity Tests · Mutagens · Occupational Exposure · Ovary · Pentanes · Pregnancy · Rats · Reproduction · Testis · Animalia · Drosophila melanogaster · Melanogaster · Salmonella typhimurium · Typhimurium
[Abstract]

13 Subacute (28-day) toxicity of furfural in Fischer 344 rats: A comparison of the oral and inhalation route
article 2004    
Author: Arts, J.H.E. · Muijser, H. · Appel, M.J. · Kuper, C.F. · Bessems, J.G.M. · Woutersen, R.A.
Keywords: Biology Health · Toxicology and Applied Pharmacology · Fischer rat · Furfural · Inhalation · Oral · Route-to-route extrapolation · Subacute toxicity · corn oil · furfural · air · animal experiment · animal model · animal tissue · article · comparative study · concentration response · controlled study · exposure · female · histopathology · kidney mass · liver weight · male · mortality · nonhuman · olfactory epithelium · rat · survival · toxicity testing · Administration, Inhalation · Administration, Oral · Animals · Dose-Response Relationship, Drug · Female · Furaldehyde · Kidney · Liver · Longevity · Male · No-Observed-Adverse-Effect Level · Olfactory Mucosa · Organ Size · Rats · Rats, Inbred F344 · Zea mays
[Abstract]

14 Local effects in the respiratory tract: Relevance of subjectively measured irritation for setting occupational exposure limits
article 2006    
Author: Arts, J.H.E. · Heer, C.de · Woutersen, R.A.
Keywords: Biology · Toxicology and Applied Pharmacology · Chemosensory effects · Odorous irritants · Olfactory stimulation · Respiratory tract · Acetone · Formaldehyde · Furfural · Sulfur dioxide · Animal experiment · Animal tissue · Breathing rate · Concentration response · Controlled study · Disease severity · Incidence · Information retrieval · Medical literature · Nonhuman · Nose irritation · Perceptive threshold · Questionnaire · Respiratory tract disease · Review · Validation process · Voluntary reporting · Air Pollutants, Occupational · Animals · Humans · Irritants · Occupational Diseases · Occupational Exposure · Odors · Respiratory System · Smell · Threshold Limit Values · Animalia
[Abstract]

15 Digestibility of resistant starch containing preparations using two in vitro models
article 2006    
Author: Fässler, C. · Arrigoni, E. · Venema, K. · Hafner, V. · Brouns, F. · Amadò, R.
Keywords: Nutrition · Biomedical Research · DSC · In vitro digestion · Resistant starch type 2 · Resistant starch type 3 · X-ray · amylose · maltodextrin · resistant starch · starch · article · comparative study · concentration response · controlled study · crystal structure · differential scanning calorimetry · digestion · food analysis · human · ileostomy · in vitro study · incubation time · maize · mechanical stress · model · molecular dynamics · protein analysis · protein content · tapioca · X ray analysis · Amylose · Dietary Fiber · Digestion · Dose-Response Relationship, Drug · Polysaccharides · Starch · Substrate Specificity · Time Factors · Manihot esculenta · Zea mays
[Abstract]

16 Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya
article 2009    
Author: Vermeulen, M. · Boerboom, A.M.M.J.F. · Blankvoort, B.M.G. · Aarts, J.M.M.J.G. · Rietjens, I.M.C.M. · Bladeren, P.J. van · Vaes, W.H.J.
Keywords: Biology · Analytical research · Antioxidant · Electrophile-responsive element · Isothiocyanate · electrophile · glutathione s transferase Ya · glutathione transferase · isothiocyanic acid derivative · luciferase · phenyl isothiocyanate · sulforaphane · unclassified drug · animal cell · article · cell assay · cell line · chemical structure · concentration response · controlled study · drug potency · enzyme induction · gene expression regulation · gene induction · gene location · mouse · nonhuman · reporter gene · Animals · Cell Line · Cell Survival · Gene Expression Regulation · Genes, Reporter · Glutathione Transferase · Isothiocyanates · Luciferases · Mice · Response Elements · Murinae
[Abstract]

17 Measurement of Biologically Available Naphthalene in Gas and Aqueous Phases by Use of a Pseudomonas putida Biosensor
article 2004    
Author: Werlen, C. · Jaspers, M.C.M. · Meer, J.R. van der
Keywords: Biology · Biotechnology · Bioluminescence · Biosensors · Calibration · Genes · Detection limits · Naphthalene · naphthalene derivative · aqueous solution · article · bioluminescence · biosensor · calibration · cell transport · chromosome insertion · concentration response · gas analysis · gene construct · gene fusion · immobilization · luxab gene · nonhuman · organic pollution · partition coefficient · plasmid · promoter region · Pseudomonas putida · sal gene · sensitivity analysis · solubility · suspension · validation process · Bacterial Proteins · Biosensing Techniques · Chemiluminescent Measurements · Culture Media · Environmental Monitoring · Gases · Luciferases · Naphthalenes · Pseudomonas putida · Transcription Factors · Water · Bacteria (microorganisms) · insertion sequences · Negibacteria · Pseudomonas · Pseudomonas putida
[PDF] [Abstract]

18 Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells
article 2004    
Author: Erk, M.J. van · Teuling, E. · Staal, Y.C.M. · Huybers, S. · Bladeren, P.J. van · Aarts, J.M.M.J.G. · Ommen, B. van
Keywords: Health Drugs · Physiological Sciences · complementary DNA · curcumin · cytochrome P450 · functional group · metallothionein · protein p53 · cancer cell culture · cell adhesion · cell cycle G2 phase · cell strain CACO 2 · cell strain HT29 · cell type · colon cancer · colon carcinogenesis · concentration response · controlled study · DNA microarray · DNA repair · down regulation · exposure · flow cytometry · gene expression profiling · genetic transcription · human · human cell · nucleotide sequence · phase transition · review · sensitivity analysis · signal transduction · time · unindexed sequence · xenobiotic metabolism
[Abstract]

19 Application of physiologically based toxicokinetic modelling to study the impact of the exposure scenario on the toxicokinetics and the behavioural effects of toluene in rats
article 2003    
Author: Asperen, J. van · Rijcken, W.R.P. · Lammers, J.H.C.M.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Peak exposure · Physiologically based toxicokinetic modelling · Rat · Toluene · toluene · animal experiment · area under the curve · article · behavior · blood level · brain level · concentration response · controlled study · exposure · male · model · nonhuman · prediction · priority journal · rat · reliability · task performance · tissue level · toxicokinetics · visual discrimination · Administration, Inhalation · Animals · Behavior, Animal · Brain · Discrimination Learning · Dose-Response Relationship, Drug · Inhalation Exposure · Models, Biological · Rats · Toluene · Visual Perception
[Abstract]

20 Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone
article 2003    
Author: Roza, L. · Vogel, N. de · Delft, J.H.M. van
Keywords: Biology Health · Physiological Sciences · Antimutagen · Clastogenicity · Human lymphocytes · Hydroquinone · Mutagenicity · hydrogen peroxide · hydroquinone · hydroquinone derivative · mutagenic agent · oxidizing agent · article · concentration response · controlled study · cytotoxicity · genotoxicity · human · human cell · lymphocyte culture · male · metabolic activation · mutagenicity · normal human · structural chromosome aberration · animal · biotransformation · cell culture · chromatid · chromosome aberration · drug effect · in vitro study · liver · lymphocyte · metabolism · mutagen testing · rat · Wistar rat · Animalia · Animals · Biotransformation · Cells, Cultured · Chromatids · Chromosome Aberrations · Humans · Hydrogen Peroxide · Hydroquinones · Liver · Lymphocytes · Male · Mutagenicity Tests · Mutagens · Oxidants · Rats · Rats, Wistar
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 44 found. Next | Sort by date