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1 The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE2 synthesis and cytotoxicity in human colorectal carcinoma cell lines
article 2003    
Author: Dommels, Y.E.M. · Haring, M.M.G. · Keestra, N.G.M. · Alink, G.M. · Bladeren, P.J. van · Ommen, B. van
Keywords: Biology · Analytical research · 5 (4 fluorophenyl) 1 [(4 methylsulfonyl)phenyl] 3 trifluoromethylpyrazole · 5,8,11,14,17 icosapentaenoic acid · acetylsalicylic acid · alpha tocopherol · antioxidant · arachidonic acid · ascorbic acid · carbene · celecoxib · cyclooxygenase 2 inhibitor · docosahexaenoic acid · indometacin · interleukin 1beta · linoleic acid · malonaldehyde · nonsteroid antiinflammatory agent · omega 3 fatty acid · omega 6 fatty acid · prostaglandin E2 · prostaglandin synthase · antineoplastic activity · cancer cell · cell growth · cell proliferation · colon cancer · colorectal carcinoma · controlled study · cytotoxicity · drug effect · drug mechanism · enzyme activation · enzyme activity · fatty acid synthesis · growth inhibition · human · human cell · hypothesis · incubation time · lipid peroxidation · priority journal · review · signal transduction · Antioxidants · Caco-2 Cells · Cell Division · Colorectal Neoplasms · Cyclooxygenase Inhibitors · Dinoprostone · Fatty Acids, Omega-3 · Fatty Acids, Omega-6 · Fatty Acids, Unsaturated · HT29 Cells · Humans · Lipid Peroxidation · Prostaglandin-Endoperoxide Synthases
[Abstract]

2 Expression profiling of colon cancer cell lines and colon biopsies: Towards a screening system for potential cancer-preventive compounds
article 2005    
Author: Erk, M.J. van · Krul, C.A.M. · Caldenhoven, E. · Stierum, R.H. · Peters, W.H. · Woutersen, R.A. · Ommen, B. van
Keywords: Health · Toxicology and Applied Pharmacology · Cancer prevention · Cell lines · Colon biopsies · Colon cancer · Expression profiling · APC protein · Beta catenin · Complementary DNA · Cyclooxygenase 2 · Protein p53 · Adult · Cancer cell culture · Cancer prevention · Cancer research · Cancer screening · Cancer staging · Clinical article · Colon biopsy · Colon cancer · Controlled study · Data analysis · DNA microarray · Female · Gene expression · Genetic analysis · Human · Human cell · Hybridization · Immune response gene · Male · Mutation · Nucleotide sequence · Oncogene c myc · Oncogene ras · Principal component analysis · Priority journal · Protein expression · RNA isolation · Tumor suppressor gene · Adenocarcinoma · Adult · Biopsy · Cell Line, Tumor · Colonic Neoplasms · Female · Gastric Mucosa · Gene Expression Profiling · Gene Expression Regulation, Neoplastic · Genes, Neoplasm · Genetic Screening · Humans · Male · Middle Aged · Mutation, Missense · Neoplasm Proteins · Oligonucleotide Array Sequence Analysis · RNA, Neoplasm · Tumor Markers, Biological
[Abstract]

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