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1 Effect of eugenol on the mutagenicity of benzo[a]pyrene and the formation of benzo[a]pyrene-DNA adducts in the X-lacZ-transgenic mouse.
article 1996    
Author: Rompelberg, C.J.M. · Steenwinkel, M.J.S.T. · Asten, J.G. van · Delft, J.H.M. van · Baan, R.A. · Verhagen, H.
Keywords: Toxicology · Antimutagenicity · Benzo[a]pyrene · DNA adduct · Eugenol · Transgenic mouse · benzo[a]pyrene · eugenol · animal experiment · article · controlled study · dna adduct · genotoxicity · male · mouse · mutagenicity · mutation rate · nonhuman · oral drug administration · priority journal · transgenic mouse · Animals · Antimutagenic Agents · Benzo(a)pyrene · Biotransformation · Body Weight · Diet · DNA Adducts · Eugenol · Glutathione Transferase · Lac Operon · Liver · Male · Mice · Mice, Transgenic · Mutagens · Phosphorus Radioisotopes · Animalia · Gale · Mus musculus
[Abstract]

2 Biological effect markers for exposure to carcinogenic compound and their relevance for risk assessment
article 1998    
Author: Delft, J.H.M. van · Baan, R.A. · Roza, L.
Keywords: Nutrition · Biomarker · Cancer mortality · Cytogenetic damage · DNA adduct · Aromatic compound · Biological marker · Cytostatic agent · Ethylene oxide derivative · Hydrocarbon · Pesticide · Animal tissue · Cancer mortality · Cancer risk · Carcinogenicity · Cell heterogeneity · Chromosome aberration · Cytogenetics · Dna adduct · Human · Human tissue · Micronucleus · Nonhuman · Pathophysiology · Population exposure · Review · Risk assessment · Animals · Carcinogens · Chromosome Aberrations · DNA Adducts · Epidemiologic Methods · Genetic Markers · Humans · Mutation · Neoplasms · Neoplasms, Experimental · Occupational Exposure · Risk Assessment · Tumor Markers, Biological
[Abstract]

3 Monitoring of occupational exposure to polycyclic aromatic hydrocarbons in a carbon-electrode manufacturing plant
article 1998    
Author: Delft, J.H.M. van · Steenwinkel, M-J.S.T. · Asten, J.G. van · Es, J. van · Kraak, A. · Baan, R.A.
Keywords: Nutrition · 1-hydroxypyrene · Biological monitoring · DNA adducts · Polycyclic aromatic hydrocarbon · Aromatic hydrocarbons · Blood · Carbon · DNA · Health · Health risks · Industrial plants · Monitoring · Personnel · Smoke · Tobacco · Biological monitoring · Carbon electrode manufacturing plant · DNA adduct · Hydroxypyrene · Lymphocyte · Occupational exposure · Polycyclic aromatic hydrocarbon · Tobacco smoking · Occupational risks · 1 hydroxypyrene · Benzo[a]pyrene · Carbon · Dna · Polycyclic aromatic hydrocarbon · Adult · Air sampling · Aluminum factory · Biological monitoring · Dna adduct · Dosimetry · Electrode · Environmental monitoring · Human · Imaging system · Industry · Lymphocyte · Normal human · Occupational exposure · Priority journal · Smoking · Standard · Urinalysis · Air Pollutants, Occupational · Case-Control Studies · DNA Adducts · Humans · Mutagens · Netherlands · Occupational Exposure · Polycyclic Hydrocarbons, Aromatic · Pyrenes · Statistics, Nonparametr
[Abstract]

4 Methyl DNA adducts, DNA repair, and hypoxanthine-guanine phosphoribosyl transferase mutations in peripheral white blood cells from patients with malignant melanoma treated with dacarbazine and hydroxyurea
article 1996    
Author: Philip, P.A. · Souliotis, V.L. · Harris, A.L. · Salisbury, A. · Tates, A.D. · Mitchell, K. · Delft, J.H.M. van · Ganesan, T.S. · Kyrtopoulos, S.A.
Keywords: Biology · dacarbazine · hydroxyurea · hypoxanthine phosphoribosyltransferase · adult · aged · article · clinical article · dna adduct · dna repair · female · gene mutation · human · intravenous drug administration · leukocyte · male · melanoma · priority journal · Antineoplastic Combined Chemotherapy Protocols · Dacarbazine · DNA Adducts · DNA Repair · Female · Guanine · Humans · Hydroxyurea · Hypoxanthine Phosphoribosyltransferase · Leukocytes · Male · Melanoma · Middle Aged · Mutation · O(6)-Methylguanine-DNA Methyltransferase
[Abstract]

5 Exposure-route-dependent DNA adduct formation by polycyclic aromatic hydrocarbons
article 2000    
Author: Godschalk, R.W.L. · Moonen, E.J.C. · Schilderman, A.E.L. · Broekmans, W.M.R. · Kleinjans, J.C.S. · Schooten, F.J. van
Keywords: Nutrition · Benzo[a]pyrene · Polycyclic aromatic hydrocarbon · Animal cell · Animal experiment · Animal model · Animal tissue · Biological monitoring · Controlled study · DNA adduct · DNA binding · Environmental exposure · Leukocyte · Lung parenchyma · Male · Nonhuman · Priority journal · Skin · Urinary excretion · Animals · Benzo(a)pyrene · Benzopyrenes · DNA Adducts · Environmental Exposure · Leukocytes · Male · Rats · Rats, Inbred Lew · Regression
[Abstract]

6 Cisplatin-DNA adduct formation in rat spermatozoa and its effect on fetal development
article 2000    
Author: Hooser, S.T. · Dijk-Knijnenburg, C.M. van · Waalkens-Berendsen, I.D.H. · Smits-van Prooije, A.E. · Snoeij, N.J. · Baan, R.A. · Fichtinger-Schepman, M.J.
Keywords: Nutrition · Cisplatin · Development · DNA adducts · Embryotoxicity · Rats · Spermatozoa · Cisplatin · Animal cell · Antibody specificity · Carcinogenesis · Cell killing · Cross linking · DNA adduct · DNA binding · DNA damage · Embryotoxicity · Fetus development · Infertility · Nonhuman · Priority journal · Rat · Spermatogenesis · Spermatozoon · Animals · Body Weight · Cisplatin · DNA Adducts · DNA Damage · Embryonic and Fetal Development · Female · Fetal Death · Male · Pregnancy · Rats · Rats, Wistar · Spermatozoa · Animalia
[Abstract]

7 Induction of somatic mutations but not methylated DNA adducts in λlacZ transgenic mice by dichlorvos
article 1999    
Author: Pletsa, V. · Steenwinkel, M.-J.S.T. · Delft, J.H.M. van · Baan, R.A. · Kyrtopoulos, S.A.
Keywords: Nutrition · Dimethylsulphate · Methylating agents · N7-Methylguanine · O6-Methylguanine · Organosphosphate insecticides · 6 o methylguanine · 7 methylguanine · Dichlorvos · Dimethyl sulfate · Animal cell · Bone marrow cell · Controlled study · DNA adduct · DNA methylation · Genotoxicity · Liver cell · Mouse · Mutation rate · Nonhuman · Priority journal · Somatic mutation · Transgenic mouse · Animals · Dichlorvos · DNA Methylation · Guanine · Insecticides · Lac Operon · Mice · Mice, Transgenic · Mutation · Mus musculus
[Abstract]

8 Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients
article 1998    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Gall, H.E. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Creatinine · Adult · Aged · Area under the curve · Clinical article · Creatinine blood level · Dna adduct · Dna drug complex · Drug blood level · Drug effect · Drug half life · Female · Human · Intravenous drug administration · Kidney function · Male · Malignant neoplastic disease · Priority journal · Amifostine · Antineoplastic Agents · Cisplatin · DNA Adducts · Drug Interactions · Female · Half-Life · Hemofiltration · Humans · Leukocytes · Male · Middle Aged · Neoplasms · Platinum · Radiation-Protective Agents
[Abstract]

9 Effects of thiourea and ammonium bicarbonate on the formation and stability of bifunctional cisplatin-DNA adducts : consequences for the accurate quantification of adducts in (cellular) DNA
article 1995    
Author: Fichtinger-Schepman, A.M.J. · Dijk-Knijnenburg, H.C.M. van · Dijt, F.J. · Velde-Visser, S.D. van der · Berends, F. · Baan, R.A.
Keywords: Nutrition · Ammonium derivative · Bicarbonate · Cell dna · Cisplatin · Dna · Thiourea · Animal cell · Cho cell · Dna adduct · Drug determination · Drug dna interaction · Nonhuman · Animal · Bicarbonates · Cell Survival · CHO Cells · Chromatography, Ion Exchange · Cisplatin · Cricetulus · Deoxyribonucleases · DNA Adducts · Hamsters · Support, Non-U.S. Gov't · Thiourea · Animalia · Cricetinae · Cricetulus griseus
[Abstract]

10 DNA adducts, mutant frequencies and mutation spectra in λlacZ transgenic mice treated with N-nitrosodimethylamine
article 1998    
Author: Souliotis, V.L. · Delft, J.H.M. van · Steenwinkel, M.-J.S.T. · Baan, R.A. · Kyrtopoulos, S.A.
Keywords: Nutrition · 6 o alkylguanine dna alkyltransferase · 6 o methylguanine · 7 methylguanine · Beta galactosidase · Dimethylnitrosamine · Dna · Animal experiment · Animal tissue · Carcinogenesis · Controlled study · Dna adduct · Liver · Male · Mouse · Mutation rate · Nonhuman · Priority journal · Spleen · Transgenic mouse · Animals · Carcinogens · Dimethylnitrosamine · DNA Adducts · Lac Operon · Male · Mice · Mice, Transgenic · Mutagens · Mutation · Sequence Deletion
[Abstract]

11 Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: comparison with in vitro adduct formation
article 1990    
Author: Fichtinger-Schepman, A.M.J. · Velde van der - Visser, S.D. · Dijk van - Knijnenburg, H.C.M. · Oosterom, A.T. van · Baan, R.A. · Berends, F.
Keywords: Antineoplastic agent · Cisplatin · Endogenous compound · Adult · Blood cell · Cancer · Cancer chemotherapy · Clinical article · DNA adduct · DNA binding · Female · Human · Intravenous drug administration · Male · Priority journal · Adult · Cisplatin · Comparative Study · DNA · Female · Human · Infusions, Intravenous · Kinetics · Leukocytes · Male · Middle Age · Neoplasms · Reference Values · Support, Non-U.S. Gov't · Time Factors
[Abstract]

12 Interactions between polycyclic aromatic hydrocarbons in binary mixtures: Effects on gene expression and DNA adduct formation in precision-cut rat liver slices
article 2008    
Author: Staal, Y.C.M. · Pushparajah, D.S. · Herwijnen, M.H.M. van · Gottschalk, R.W.H. · Maas, L.M. · Ioannides, C. · Schooten, F.J. van · Delft, J.H.M. van
Keywords: Nutrition · benzo[a]pyrene · benzo[b]fluoranthene · complementary DNA · dibenz[a,h]anthracene · dibenzo[a,l]pyrene · fluoranthene · polycyclic aromatic hydrocarbon · animal experiment · animal tissue · article · carcinogenic activity · DNA adduct · DNA microarray · gene expression · gene interaction · liver slice · male · molecular interaction · nonhuman · nucleotide sequence · priority journal · rat · Animals · Carcinogens · DNA Adducts · Gene Expression · Liver · Male · Oligonucleotide Array Sequence Analysis · Polycyclic Hydrocarbons, Aromatic · Rats · Rats, Wistar · Rattus
[Abstract]

13 Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation
article 2007    
Author: Staal, Y.C.M. · Hebels, D.G.A.J. · Herwijnen, M.H.M. van · Gottschalk, R.W.H. · Schooten, F.J. van · Delft, J.H.M. van
Keywords: Toxicology and Applied Pharmacology · benzo[a]pyrene · benzo[b]fluoranthene · dibenz[a,h]anthracene · dibenzo[a,l]pyrene · fluoranthene · phenanthrene derivative · polycyclic aromatic hydrocarbon · apoptosis · article · carcinogenesis · carcinogenicity · cell cycle · cell strain HepG2 · controlled study · DNA adduct · exposure · gene expression · hepatoma cell · human · human cell · nucleotide sequence · priority journal · unindexed sequence · Air Pollutants · Apoptosis · Cell Cycle · Cell Line, Tumor · DNA Adducts · Drug Antagonism · Drug Synergism · Gene Expression Profiling · Gene Expression Regulation, Neoplastic · Humans · Polycyclic Hydrocarbons, Aromatic
[Abstract]

14 Vitamin A and β-carotene influence the level of benzo[a]pyrene-induced DNA adducts and DNA-repair activities in hamster tracheal epithelium in organ culture
article 1995    
Author: Wolterbeek, A.P.M. · Roggeband, R. · Moorsel, C.J.A. van · Baan, R.A. · Koeman, J.H. · Feron, V.J. · Rutten, A.A.J.J.L.
Keywords: Biology · β-carotene · Benzo[a]pyrene · DNA adducts · DNA repair · Tracheal organ culture · Vitamin A · benzo[a]pyrene · beta carotene · retinol · animal tissue · article · chemical carcinogenesis · controlled study · dna adduct · dna repair · hamster · immunocytochemistry · nonhuman · organ culture · priority journal · respiratory system · trachea mucosa · unscheduled dna synthesis · Animal · Benzo(a)pyrene · beta Carotene · Carotenoids · DNA Adducts · DNA Damage · DNA Repair · Epithelium · Hamsters · In Vitro · Mesocricetus · Organ Culture · Support, Non-U.S. Gov't · Trachea · Vitamin A · Animalia · Cricetinae
[Abstract]

15 Pharmacokinetics of cisplatin with and without amifostine in tumour- bearing nude mice
article 1998    
Author: Korst, A.E.C. · Boven, E. · Sterre, M.L.T. van der · Fichtinger-Schepman, A.M.J. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Ethyol · Pharmacokinetics · WR-2721 · Amifostine · Cisplatin · Dna · Animal cell · Animal experiment · Animal model · Animal tissue · Area under the curve · Article · Bone marrow · Controlled study · Dna adduct · Drug blood level · Drug tissue level · Female · Human · Human tissue · Intraperitoneal drug administration · Intravenous drug administration · Kidney · Liver · Mouse · Nonhuman · Nude mouse · Ovary cancer · Pharmacokinetics · Priority journal · Tumor xenograft · Amifostine · Animals · Antineoplastic Agents · Cisplatin · Drug Combinations · Drug Synergism · Female · Humans · Kidney · Liver · Mice · Neoplasm Transplantation · Ovarian Neoplasms · Platinum · Radiation-Protective Agents · Transplantation, Heterologous
[Abstract]

16 DNA adducts, mutant frequencies, and mutation spectra in various organs of λlacZ mice exposed to ethylating agents
article 1998    
Author: Mientjes, E.J. · Luiten-Schuite, A. · Wolf, E. van der · Borsboom, Y. · Bergmans, A. · Berends, F. · Lohman, P.H.M. · Baan, R.A. · Delft, J.H.M. van
Keywords: Nutrition · λlacZ transgenic mice · Ethyl DNA adducts · Muta(TM)Mouse · Mutagenesis · Mutation spectra · Alkylating agent · Diethylnitrosamine · Ethylnitrosourea · Guanine derivative · Mesylic acid ethyl ester · Animal experiment · Animal tissue · Bone marrow · Brain · Controlled study · Dna adduct · Female · Liver · Mouse · Mutagenesis · Mutation · Mutation rate · Nonhuman · Sequence analysis · Transgenic mouse · Animals · Bone Marrow · Brain · Diethylnitrosamine · DNA Adducts · Ethyl Methanesulfonate · Ethylnitrosourea · Female · Guanine · Lac Operon · Liver · Mice · Mice, Transgenic · Mutagens
[Abstract]

17 Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH- DNA adducts
article 1998    
Author: Randerath, K. · Sriram, P. · Moorthy, B. · Aston, J.P. · Baan, R.A. · Berg, P.T.M. van den · Booth, E.D. · Watson, W.P.
Keywords: Nutrition · 32P-postlabelling · DNA adducts · Immunoaffinity · Nuclease P1 · PAH · Nuclease · Phosphorus 32 · Polycyclic aromatic hydrocarbon · Adsorption · Animal cell · Column chromatography · Contamination · Dna adduct · Enzyme analysis · Enzyme specificity · Genotoxicity · Immunoaffinity chromatography · Mutagenicity · Nonhuman · Protein modification · 9,10-Dimethyl-1,2-benzanthracene · Animals · Antibodies, Monoclonal · Aspergillus Nuclease S1 · Benzo(a)pyrene · Carcinogens · Chromatography, Affinity · Chrysenes · DNA Adducts · Fluorescent Antibody Technique · Isotope Labeling · Mice · Mutagenicity Tests · Mutagens · Phosphorus Radioisotopes · Polycyclic Hydrocarbons, Aromatic · Skin · Animalia
[Abstract]

18 The formation and repair of cisplatin-DNA adducts in wild-type and cisplatin-resistant L1210 cells : comparison of immunocytochemical determination with detection in isolated DNA
article 1998    
Author: Blommaert, F.A. · Floot, B.G.J. · Dijk-Knijnenburg, H.C.M. van · Berends, F. · Baan, R.A. · Schornagel, J.H. · Engelse, L. den · Fichtinger-Schepman, A.M.J.
Keywords: Nutrition · Cisplatin · DNA adducts · Drug resistance · Enzyme-linked immunosorbent assay · Immunocytochemistry · antiserum · cisplatin · dna · animal cell · article · colony formation · dna adduct · dna content · dna damage · dna synthesis · drug dna binding · drug resistance · drug sensitivity · enzyme linked immunosorbent assay · growth inhibition · immunocytochemistry · mouse · nonhuman · Animals · Antineoplastic Agents · Bicarbonates · Cell Division · Cisplatin · DNA Adducts · DNA Repair · DNA, Neoplasm · Drug Resistance, Neoplasm · Enzyme-Linked Immunosorbent Assay · Immunohistochemistry · Leukemia L1210 · Mice · Sensitivity and Specificity · Thiourea · Animalia · Rodentia
[Abstract]

19 Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic polymorphisms for GSTM1 GSTT1
article 2001    
Author: Delft, J.H.M. van · Steenwinkel, M.-J.S.T. · Asten, J.G. van · Vogel, N. de · Bruijntjes-Rozier, T.C.D.M. · Schouten, T. · Cramers, P. · Maas, L. · Herwijnen, M.H. van · Schooten, F.-J. van · Hopmans, P.M.J.
Keywords: Biology · 1-OHpyr: 1-hydroxypyrene · GST: glutathione S-transferase · HFC: cells with a high frequency of SCE · MN: micronuclei · PAH: polycyclic aromatic hydrocarbons · SCE: sister-chromatid exchange · 1 Hydroxypyrene · Glutathione transferase · Polycyclic aromatic hydrocarbon · Adult · Biological monitoring · Cancer risk · Chromosome analysis · Coke oven industry · Comet assay · Controlled study · DNA adduct · DNA strand breakage · Endothelium cell · Genetic polymorphism · Human · Industrial worker · Industry · Lung cancer · Lymphocyte · Male · Micronucleus test · Multivariate analysis · Normal human · Occupational exposure · Priority journal · Sister chromatid exchange · Smoking · Urine level · Adult · Coke · DNA Adducts · Glutathione Transferase · Humans · Middle Aged · Multivariate Analysis · Occupational Exposure · Polycyclic Hydrocarbons, Aromatic · Polymorphism, Genetic · Sister Chromatid Exchange · Smoking
[Abstract]

20 Time series analysis of benzo[a]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets
article 2010    
Author: Delft, J.H.M. van · Mathijs, K. · Staal, Y.C.M. · Herwijnen, M.H.M. van · Brauers, K.J.J. · Boorsma, A. · Kleinjans, J.C.S.
Keywords: Nutrition · Biomedical Research · Carcinogen · Network · Time series · Transcription factor · Transcriptome · benzo[a]pyrene · immunoglobulin enhancer binding protein · Myc protein · serum response factor · transcription factor · transcription factor AP 1 · transcription factor E2F1 · transcriptome · amino acid metabolism · apoptosis · article · carcinogenesis · cell cycle G1 phase · cell cycle S phase · controlled study · correlation analysis · DNA adduct · DNA repair · down regulation · functional genomics · gene expression · gene regulatory network · hepatoma cell · human · human cell · lipid metabolism · named inventories, questionnaires and rating scales · proto oncogene · Short Time series Expression Miner · signal transduction · time series analysis · transcription regulation · tumor suppressor gene · upregulation
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 23 found. Next | Sort by date