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Showing 1 to 17 of 17 found. | Sort by date

1 Concentration- and time-related effects of sulphur mustard on human epidermal keratinocyte function
article 1992    
Author: Mol, M.A.E. · Vries-Van de Ruit, A.M.B.C. de
Keywords: Adenosine triphosphate · Lactate dehydrogenase · Mustard gas · Nicotinamide adenine dinucleotide · Cell culture · Cell growth · DNA synthesis · DNA synthesis inhibition · Human · Human cell · Keratinocyte · Priority journal · Protein synthesis inhibition
[Abstract]

2 Lack of effect of coumarin on unscheduled DNA synthesis in the in vivo rat hepatocyte DNA repair assay
article 2000    
Author: Edwards, A.J. · Price, R.J. · Renwick, A.B. · Lake, B.G.
Keywords: In vivo DNA repair · Rat hepatocytes · Unscheduled DNA synthesis · dimethylnitrosamine · n (2 fluorenyl)acetamide · animal cell · chromosome aberration · controlled study · liver cell · liver toxicity · nonhuman · sister chromatid exchange · unscheduled DNA synthesis · 2-Acetylaminofluorene · Animals · Anticoagulants · Cell Separation · Cells, Cultured · Coumarins · Dimethylnitrosamine · DNA · DNA Repair · DNA Replication · Liver · Male · Mutagens · Rats · Rats, Sprague-Dawley · Animalia · Zea mays
[Abstract]

3 The mutagenicity of isoniazid in salmonella and its effects on DNA repair and synthesis in human fibroblasts
article 1980    
Author: Wade, D.R. · Lohman, P.H.M.
Keywords: Biology · Hydrazine · Isoniazid · Manganese · Abstract report · Adverse drug reaction · Cell culture · Chemical mutagenesis · DNA repair · DNA synthesis · Fibroblast · Human · Human cell · In vitro study · Liver microsome · Mouse · Mutagenicity · Normal human · Pharmacokinetics · Rat · Salmonella · Salmonella typhimurium · Soft tissue
[Abstract]

4 On the antifungal mode of action of metalaxyl, an inhibitor of nucleic acid synthesis in Pythium splendens
article 1981    
Author: Kerkenaar, A.
Keywords: Biology · Metalaxyl · Mithramycin · Radioisotope · Animal experiment · Bisbenzimide h 3 · Cytotoxicity · Dna synthesis · Drug absorption · Drug mechanism · Fungus · Heredity · Histology · Lipogenesis · Metalaxyl c 14 · Nucleic acid synthesis · Oomycetes · Protein synthesis · Rna synthesis
[Abstract]

5 Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 gene expression in the rat, Syrian hamster and guinea pig
article 2000    
Author: Lake, B.G. · Rumsby, P.C. · Price, R.J. · Cunninghame, M.E.
Keywords: Hepatic peroxisome proliferation · Replicative DNA synthesis · Species differences · Syrian hamster · Transforming growth factor-β1 · ciprofibrate · messenger RNA · methylclofenapate · peroxisome proliferator · peroxisome proliferator activated receptor · pirinixic acid · somatomedin B receptor · transforming growth factor beta1 · animal model · animal tissue · cell division · controlled study · DNA synthesis · enzyme activity · fatty acid oxidation · liver weight · nonhuman · species difference · Syrian hamster · Animals · Cell Division · Clofenapate · Clofibric Acid · Cricetinae · DNA · Gene Expression · Guinea Pigs · Liver · Male · Mesocricetus · Molecular Structure · Organ Size · Peroxisome Proliferators · Pyrimidines · Rats · Rats, Sprague-Dawley · Receptor, IGF Type 2 · Species Specificity · Transforming Growth Factor beta · Cavia · Cavia porcellus · Cricetinae · Mesocricetus auratus · Rodentia · Sus scrofa · Zea mays
[Abstract]

6 Genotoxicity and mutagenicity
article 2005    
Author: Maurici, D. · Aardema, M. · Corvi, R. · Kleber, M. · Krul, C.A.M. · Laurent, C. · Loprieno, N. · Pasanen, M. · Pfuhler, S. · Phillips, B. · Sabbioni, E. · Sanner, T. · Vanparys, P.
Keywords: Toxicology · Physiological sciences · Animal testing replacement · Animal testing alternatives · Chromosome aberration · Comet assay · DNA damage · DNA synthesis · Gene mutation · Genotoxicity · In vitro study · In vivo study · Micronucleus test · Mitotic recombination · Mutagenicity · Sister chromatid exchange · Toxicity testing · Toxicogenetics · Toxicokinetics · Toxicological parameters · Carcinogen testing · Cell culture · Chemistry · Legal aspects · Structure activity relation · Animalia · Consumer product safety · Cosmetics · European Union · Structure-Activity Relationship

7 Agrobacterium-mediated transformation as a tool for functional genomics in fungi
article 2005    
Author: Michielse, C.B. · Hooykaas, P.J.J. · Hondel, C.A.M.J.J. van den · Ram, A.F.J.
Keywords: Biology · Analytical research · Agrobacterium tumefaciens · Fungal transformation · Insertional mutagenesis · Targeted mutagenesis · bacterial DNA · DNA integration · DNA synthesis · DNA transfer · functional genomics · fungal genetics · fungal strain · gene expression regulation · gene targeting · genetic transformation · molecular genetics · nonhuman · priority journal · review · Rhizobium · Rhizobium radiobacter · Bacterial Proteins · Base Sequence · DNA, Fungal · Genome, Fungal · Genomics · Mutagenesis, Insertional · Mutagenesis, Site-Directed · Plasmids · Rhizobium · Saccharomyces cerevisiae · Agrobacterium · Agrobacterium tumefaciens · Fungi
[Abstract]

8 Statistically designed experiments to screen chemical mixtures for possible interactions
article 1998    
Author: Groten, J.P. · Tajima, O. · Feron, V.J. · Schoen, E.D.
Keywords: Chemistry · Bioassay · Box Behnken design · Central composite design · Factorial design · Fractionated factorial design · Mixtures · Mycotoxins · Mycotoxin · Accuracy · Analysis · Chemical interaction · Conference paper · Cytotoxicity · DNA synthesis inhibition · Factorial analysis · Fibroblast · Food contamination · Fusarium · Priority journal · Screening · Statistical analysis · Algorithms · Cell Line · Data Interpretation, Statistical · DNA · Drug Interactions · Humans · Mycotoxins · Research Design · Toxicity Tests · Fusarium
[PDF] [Abstract]

9 Contrasting responses to interferon β-1b treatment in relapsing-remitting multiple sclerosis: Does baseline interleukin- 12p35 messenger RNA predict the efficacy of treatment?
article 2000    
Author: Boxel van-Dezaire, A.H.H. · Trigt van-Hoff, S.C.J. · Killestein, J. · Schrijver, H.M. · Houwelingen, J.C. van · Polman, C.H. · Nagelkerken, L.
Keywords: Health · Gamma interferon · Interferon beta serine · Interleukin 10 · Interleukin 12 · Interleukin 12 receptor · Interleukin 18 · Messenger RNA · Protein p35 · Protein p40 · Clinical article · Disability · Disease classification · DNA synthesis · Drug efficacy · Gene expression · Multiple sclerosis · Prediction · Rating scale · Recurrent disease · Treatment outcome · Adult · Female · Humans · Interferon-beta · Interleukin-12 · Male · Multiple Sclerosis, Relapsing-Remitting · Predictive Value of Tests · RNA, Messenger · Time Factors
[Abstract]

10 Platinum compounds with anti-tumour activity
article 1980    
Author: Plooy, A.C.M. · Lohman, P.H.M.
Keywords: Biology · Antineoplastic agent · Cisplatin · Platinum derivative · Radioisotope · Animal experiment · Cytotoxicity · DNA damage · DNA strand breakage · DNA synthesis · Drug toxicity · Endocrine system · Female genital system · Heredity · In vitro study · Intoxication · Mutagenesis · Mutagenicity · Ovary cell · Structure activity relation · Thymidine h 3 · Alkalies · Animal · Antineoplastic Agents · DNA · DNA Replication · Hamsters · In Vitro · Platinum · Structure-Activity Relationship · Support, Non-U.S. Gov't
[Abstract]

11 The mutagenicity of isoniazid in salmonella and its effects on DNA repair and synthesis in human fibroblasts
article 1981    
Author: Wade, D.R. · Lohman, P.H.M. · Mattern, I.E. · Berends, F.
Keywords: Biology · Aroclor 1254 · Hydrazine · Isoniazid · Polychlorinated biphenyl · Radioisotope · Ames test · Animal experiment · Bacterium · DNA repair · DNA synthesis · Fibroblast · Fibroblast culture · Heredity · In vitro study · Mutagenicity · Salmonella typhimurium · Thymidine c 14 · Thymidine h 3 · Cells, Cultured · DNA · DNA Repair · Human · Hydrazines · Isoniazid · Manganese · Mutagenicity Tests · Mutagens · Salmonella typhimurium · Support, Non-U.S. Gov't
[Abstract]

12 Effect of D-tagatose on liver weight and glycogen content of rats
article 1999    
Author: Bär, A. · Lina, B.A.R. · Groot, D.M.G. de · Bie, B. de · Appel, M.J.
Keywords: Nutrition · Acyl coenzyme a oxidase · Glycogen · Lauric acid derivative · Lipid · Liver protein · Tagatose · Animal cell · Animal experiment · Animal model · Animal tissue · Body weight · Controlled study · DNA content · DNA synthesis · Dose response · Glycogen liver level · Lipid liver level · Liver weight · Male · Nonhuman · Priority journal · Rat · Toxicity testing · Animals · Body Weight · Cecum · Cell Nucleus · DNA · Eating · Hexoses · Liver · Liver Glycogen · Male · Microscopy, Electron · Organ Size · Peroxisome Proliferators · Rats · Rats, Sprague-Dawley · Sweetening Agents
[Abstract]

13 The formation and repair of cisplatin-DNA adducts in wild-type and cisplatin-resistant L1210 cells : comparison of immunocytochemical determination with detection in isolated DNA
article 1998    
Author: Blommaert, F.A. · Floot, B.G.J. · Dijk-Knijnenburg, H.C.M. van · Berends, F. · Baan, R.A. · Schornagel, J.H. · Engelse, L. den · Fichtinger-Schepman, A.M.J.
Keywords: Nutrition · Cisplatin · DNA adducts · Drug resistance · Enzyme-linked immunosorbent assay · Immunocytochemistry · antiserum · cisplatin · dna · animal cell · article · colony formation · dna adduct · dna content · dna damage · dna synthesis · drug dna binding · drug resistance · drug sensitivity · enzyme linked immunosorbent assay · growth inhibition · immunocytochemistry · mouse · nonhuman · Animals · Antineoplastic Agents · Bicarbonates · Cell Division · Cisplatin · DNA Adducts · DNA Repair · DNA, Neoplasm · Drug Resistance, Neoplasm · Enzyme-Linked Immunosorbent Assay · Immunohistochemistry · Leukemia L1210 · Mice · Sensitivity and Specificity · Thiourea · Animalia · Rodentia
[Abstract]

14 Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle
article 1996    
Author: Vliet, A.K. van · Nègre-Arrariou, P. · Thiel, G.C.F. van · Bolhuis, P.A. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitors · Human myoblasts · Sterol synthesis · Adenosine triphosphate · Hydroxymethylglutaryl coenzyme a reductase inhibitor · Mevinolin · Mitochondrial enzyme · Cell culture · Cell proliferation · Cell viability · Concentration response · Controlled study · Dna synthesis · Human cell · Human tissue · Muscle biopsy · Myoblast · Myopathy · Skeletal muscle · Acetic Acid · Adenosine Triphosphate · Anticholesteremic Agents · Cell Division · Cell Survival · Cells, Cultured · DNA · Enzyme Inhibitors · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Mitochondria · Muscle, Skeletal · Oxidoreductases · Pravastatin · Simvastatin · Sterols
[Abstract]

15 Vitamin A and β-carotene influence the level of benzo[a]pyrene-induced DNA adducts and DNA-repair activities in hamster tracheal epithelium in organ culture
article 1995    
Author: Wolterbeek, A.P.M. · Roggeband, R. · Moorsel, C.J.A. van · Baan, R.A. · Koeman, J.H. · Feron, V.J. · Rutten, A.A.J.J.L.
Keywords: Biology · β-carotene · Benzo[a]pyrene · DNA adducts · DNA repair · Tracheal organ culture · Vitamin A · benzo[a]pyrene · beta carotene · retinol · animal tissue · article · chemical carcinogenesis · controlled study · dna adduct · dna repair · hamster · immunocytochemistry · nonhuman · organ culture · priority journal · respiratory system · trachea mucosa · unscheduled dna synthesis · Animal · Benzo(a)pyrene · beta Carotene · Carotenoids · DNA Adducts · DNA Damage · DNA Repair · Epithelium · Hamsters · In Vitro · Mesocricetus · Organ Culture · Support, Non-U.S. Gov't · Trachea · Vitamin A · Animalia · Cricetinae
[Abstract]

16 Effect of eugenol on the genotoxicity of established mutagens in the liver
article 1996    
Author: Rompelberg, C.J.M. · Evertz, S.J.C.J. · Bruijntjes-Rozier, G.C.D.M. · Heuvel, P.D. van den · Verhagen, H.
Keywords: Toxicology · aflatoxin b1 · benzo[a]pyrene · dimethylbenz[a]anthracene · eugenol · mutagenic agent · animal experiment · animal tissue · article · controlled study · genotoxicity · hepatoma cell · human · human cell · liver · male · metabolic activation · mutagenicity · nonhuman · oral drug administration · rat · salmonella typhimurium · unscheduled dna synthesis · 9,10-Dimethyl-1,2-benzanthracene · Aflatoxin B1 · Animals · Antimutagenic Agents · Benzo(a)pyrene · Carcinoma, Hepatocellular · Cytochrome P-450 Enzyme System · DNA · Electrophoresis, Agar Gel · Eugenol · Glutathione Transferase · Humans · Liver · Liver Neoplasms · Male · Micronucleus Tests · Mutagenicity Tests · Mutagens · Rats · Rats, Wistar · Salmonella typhimurium · Tumor Cells, Cultured
[Abstract]

17 Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
article 2007    
Author: Pires, N.M.M. · Pols, T.W.H. · Vries, M.R. de · Tiel, C.M.van · Bonta, P.I. · Vos, M. · Arkenbout, E.K. · Pannekoek, H. · Jukema, J.W. · Quax, P.H.A. · Vries, C.J.M. de
Keywords: Biology · Biomedical Research · Muscle, smooth · Receptors, cytoplasmic and nuclear · Restenosis · Stents · Transcription factors · cyclin dependent kinase inhibitor 1B · cycline · mercaptopurine · messenger RNA · nuclear receptor Nur77 · polycaprolactone · small interfering RNA · staurosporine · thymidine · tritium · animal experiment · animal model · animal tissue · antiangiogenic activity · antigen expression · apoptosis · artery intima proliferation · article · blood vessel injury · blood vessel wall · cell culture · cell cycle arrest · cell proliferation · controlled study · DNA synthesis · drug delivery system · drug dose comparison · drug effect · elution · experimental model · femoral artery · gene overexpression · human · human cell · hypothesis · in-stent restenosis · inflammation · intima · local therapy · male · mouse · nonhuman · observation · priority journal · protein expression · receptor down regulation · receptor upregulation · smooth muscle fiber · sustained drug release · transgenic mouse · vascular smooth muscle · wild type · 6-Mercaptopurine · Animals · Antimetabolites, Antineoplastic · Apoptosis · Cell Division · Cells, Cultured · Coronary Restenosis · Disease Models, Animal · DNA-Binding Proteins · Drug Implants · Femoral Artery · Humans · Male · Mice · Mice, Inbred Strains · Mice, Transgenic · Muscle, Smooth, Vascular · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · RNA, Small Interfering · Transcription Factors · Tunica Intima · Umbilical Arteries
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 17 of 17 found. | Sort by date