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Showing 1 to 14 of 14 found. | Sort by date

1 Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals
article 2005    
Author: Stierum, R. · Heijne, W. · Kienhuis, A. · Ommen, B. van · Groten, J.
Keywords: Toxicology Nutrition · Physiological Sciences · In vitro · In vivo · Liver · Toxicogenomics · bromobenzene · butylcresol · chemical compound · curcumin · food additive · gallic acid propyl ester · proteome · tiabendazole · transcriptome · biochemistry · bioinformatics · comparative toxicology · conference paper · disease marker · DNA fingerprinting · gene expression profiling · genetic procedures · genetic toxicology · genomics · in vitro study · in vivo study · laboratory · liver toxicity · metabolomics · molecular biology · nonhuman · prediction · proteomics · rat · technology · toxicological parameters · transcriptomics · Animals · Food Additives · Genomics · Humans · Liver · Toxicology
[Abstract]

2 Serum carotenoids and vitamins in relation to markers of endothelial
article 2004    
Author: Herpen-Broekmans, W. van · Klöpping-Ketelaars, I. · Michiel, B. · Cornelis, K. · Hans, P. · Hendriks, F.J. · Tijburg, L. · Poppel, G. van · Kardinaal, A.
Keywords: Nutrition Health · Physiological Sciences · Carotenoids · Endothelial function · Inflammation · Vitamins · Alpha tocopherol · Ascorbic acid · Beta carotene · Beta cryptoxanthin · C reactive protein · Carotenoid · Intercellular adhesion molecule 1 · Lycopene · Unclassified drug · Zeaxanthin · Blood flow · Disease marker · Inflammation · Leukocyte · Population research · Vascular endothelium · Vasodilatation · Vitamin blood level · Adult · Alpha-Tocopherol · Ascorbic Acid · Beta Carotene · Biological Markers · C-Reactive Protein · Carotenoids · Cross-Sectional Studies · Endothelium, Vascular · Female · Fibrinogen · Humans · Intercellular Adhesion Molecule-1 · Male · Middle Aged · Smoking · Xanthophylls
[Abstract]

3 Collagen-induced arthritis in rhesus monkeys: Evaluation of markers for inflammation and joint degradation
article 1998    
Author: Hart, B.A. 't · Bank, R.A. · Roos, J.A.D.M. de · Brok, H. · Jonker, M. · Theuns, H.M. · Hakimi, J. · Koppele, J.M.Te.
Keywords: Nutrition · Collagen-induced arthritis · Disease markers · Rhesus monkey · C reactive protein · Collagen · Cyclosporin a · Deoxypyridinoline · Pyridinoline · Animal experiment · Animal model · Arthritis · Blood level · Cartilage degeneration · Controlled study · Diagnostic value · Disease activity · Disease course · Disease marker · Disease predisposition · Disease severity · Female · Inflammation · Joint degeneration · Male · Nonhuman · Priority journal · Remission · Rhesus monkey · Urine level · Weight gain · Weight reduction · Amino Acids · Animals · Antirheumatic Agents · Arthritis, Experimental · Biological Markers · C-Reactive Protein · Collagen · Cross-Linking Reagents · Cyclosporine · Female · Joints · Macaca mulatta · Male · Synovial Fluid · Weight Loss
[Abstract]

4 Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis
article 2003    
Author: Tchetverikov, I. · Lard, L.R. · Groot, J. de · Verzijl, N. · TeKoppele, J.M. · Breedveld, F.C. · Huizinga, T.W.J. · Hanemaaijer, R.
Keywords: Biology · Biomedical Research · gelatinase B · neutrophil collagenase · stromelysin · aged · arthropathy · disease activity · disease course · disease marker · enzyme activity · enzyme blood level · enzyme linked immunosorbent assay · female · human · joint destruction · longitudinal study · major clinical study · male · prediction · rheumatoid arthritis · Adult · alpha-Macroglobulins · Arthritis, Rheumatoid · Biological Markers · C-Reactive Protein · Disease Progression · Female · Humans · Joints · Male · Matrix Metalloproteinase 3 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Middle Aged · Prospective Studies · Statistics, Nonparametric
[Abstract]

5 Effect of type of alcoholic beverages on carbohydrate-deficient transferrin, sialic acid, and liver enzymes
article 2003    
Author: Sillanaukee, P. · Gaag, M.S. van der · Sierksma, A. · Hendriks, H.F.J. · Strid, N. · Pönniö, M. · Nikkari, S.T.
Keywords: Health · Physiological Sciences · Alcoholic Beverages · Markers of Alcohol Use Disorders · Moderate Drinking · alanine aminotransferase · alcohol · aspartate aminotransferase · carbohydrate deficient transferrin · gamma glutamyltransferase · liver enzyme · sialic acid · water · adult · alcohol consumption · alcoholic beverage · alcoholism · article · beer · clinical trial · controlled clinical trial · controlled study · crossover procedure · disease marker · drinking behavior · enzyme blood level · gin · human · iron metabolism · male · meal · normal human · priority journal · randomized controlled trial · wine · Adult · Alanine Transaminase · Alcoholic Beverages · Analysis of Variance · Aspartate Aminotransferases · Beer · Biological Markers · gamma-Glutamyltransferase · Humans · Liver · Male · Middle Aged · N-Acetylneuraminic Acid · Transferrin · Wine
[Abstract]

6 Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic guinea pigs
article 2003    
Author: Lamers, R.-J.A.N. · Groot, J. de · Spies-Faber, E.J. · Jellema, R.H. · Kraus, V.B. · Verzijl, N. · Koppele, J.M. te · Spijksma, G.K. · Vogels, J.T.W.E. · Greef, J. van der · Nesselrooij, J.H.J. van
Keywords: Biology · Analytical research · Biomedical research · 1H NMR spectroscopy · Metabolic fingerprinting · Multivariate data analysis · Osteoarthritis · Vitamin C · ascorbic acid · biological marker · purine · animal experiment · animal model · article · controlled study · data analysis · dietary intake · disease marker · energy metabolism · guinea pig · inbred strain · male · metabolic fingerprint · metabolism · metabolite · multivariate analysis · nonhuman · nutrient · nutrition · osteoarthritis · pathophysiology · proton nuclear magnetic resonance · purine metabolism · strain difference · urinalysis · vitamin intake · Animal Nutrition Physiology · Animals · Ascorbic Acid · Diet · Dose-Response Relationship, Drug · Energy Metabolism · Guinea Pigs · Magnetic Resonance Spectroscopy · Male · Multivariate Analysis · Osteoarthritis · Peptide Mapping · Purines · Treatment Outcome · Animalia · Cavia · Cavia porcellus · Sus scrofa
[Abstract]

7 Active MMPs captured by alpha2Macroglobulin as a marker of disease activity in rheumatoid arthritis
article 2003    
Author: Tchetverikov, I. · Verzijl, N. · Huizinga, T.W.J. · TeKoppele, J.M. · Hanemaaijer, R. · Groot, J. de
Keywords: Biology · Biomedical Research · α2Macroglobulin · Matrix metalloproteases · Rheumatoid arthritis · alpha 2 macroglobulin · batimastat · collagenase 3 · matrix metalloproteinase · tissue inhibitor of metalloproteinase 1 · article · circulation · clinical article · complex formation · concentration (parameters) · controlled study · correlation analysis · disease activity · disease course · disease marker · enzyme linked immunosorbent assay · erythrocyte sedimentation rate · fast protein liquid chromatography · fluorescence analysis · human · molecular weight · priority journal · protein analysis · protein blood level · quantitative analysis · rheumatoid arthritis · Adult · alpha-Macroglobulins · Arthritis, Rheumatoid · Biological Markers · Case-Control Studies · Disease Progression · Enzyme-Linked Immunosorbent Assay · Female · Humans · Male · Matrix Metalloproteinases · Middle Aged · Probability · Prognosis · Reference Values · Sensitivity and Specificity · Severity of Illness Index
[PDF] [Abstract]

8 Analytical strategies in lipidomics and applications in disease biomarker discovery
article 2009    
Author: Hu, C. · Heijden, R. van der · Wang, M. · Greef, J. van der · Hankemeier, T. · Xu, G.
Keywords: Biology Health · Analytical research · Lipid profiling · Lipid-associated disorders · Alzheimer's disease · Analytical strategy · Chromatographic techniques · Comprehensive analysis · Disease biomarker · Human disease · Human health · Lipidomics · Metabolomics · Molecular species · Rapid expansion · Research fields · Technological advancement · Biological systems · Biomarkers · Lipids · Mass spectrometry · Information management · Biological marker · Ceramide · Cholesterol ester · Glycerophosphoethanolamine · Glycerophosphorylcholine · Inositol phosphate · Long chain triacylglycerol · Lysophosphatidylcholine · Phosphatidylcholine · Phosphoserine · Sulfatide · Alzheimer disease · Atherosclerosis · Chemical structure · Diabetes mellitus · Disease marker · Electrospray mass spectrometry · High performance liquid chromatography · Human · Lipid analysis · Lipid metabolism · Lipidomics · Liquid chromatography · Mass spectrometry · Matrix assisted laser desorption ionization time of flight mass spectrometry · Nonhuman · Nuclear magnetic resonance spectroscopy · Obesity · Priority journal · Review · Sensitivity and specificity · Thin layer chromatography
[Abstract]

9 Soluble biomarkers of cartilage and bone metabolism in early proof of concept trials in psoriatic arthritis: Effects of adalimumab versus placebo
article 2010    
Author: Tak, P.P. · Kuijk, A.W.R. van · Groot, J. de · Koeman, R.C. · Sakkee, N. · Baeten, D.L. · Gerlag, D.M.
Keywords: Health · Biomedical Research · adalimumab · amino terminal cross linked telopeptide of type 1 collagen · C propeptide of type 2 collagen · carboxy terminal cross linked telopeptide of type 1 collagen · cartilage oligomeric matrix protein · collagen type 1 · collagen type 2 · osteocalcin · placebo · procollagen · procollagen serum type 1 amino terminal propeptide · stromelysin · unclassified drug · article · bone metabolism · cartilage cell · cartilage metabolism · clinical article · clinical trial · controlled clinical trial · controlled study · correlation analysis · disease marker · drug efficacy · human · ossification · protein analysis · protein blood level · protein degradation · protein function · protein synthesis · psoriatic arthritis · randomized controlled trial · tissue metabolism
[PDF] [Abstract]

10 Interleukin 10: A new risk marker for the development of restenosis after percutaneous coronary intervention
article 2007    
Author: Monraats, P.S. · Kurreeman, F.A.S. · Pons, D. · Sewgobind, V.D.K.D. · Vries, F.R. de · Zwinderman, A.H. · Maat, M.P.M. de · Doevendans, P.A. · Winter, R.J. de · Tio, R.A. · Waltenberger, J. · Huizinga, T.W.J. · Eefting, D. · Quax, P.H.A. · Frants, R.R. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Health · Biomedical Research · alanine · clopidogrel · cysteine · glycine · interleukin 10 · ticlopidine · adult · aged · article · cardiovascular risk · confidence interval · controlled study · coronary artery bypass graft · disease marker · DNA flanking region · DNA microarray · drug eluting stent · female · gene linkage disequilibrium · gene locus · genetic association · genetic polymorphism · genetic predisposition · genetic risk · genetic variability · genotype · heart infarction · human · hypothesis · in-stent restenosis · major clinical study · male · pathogenesis · percutaneous coronary intervention · priority journal · risk factor · 3' Untranslated Regions · Aged · Angioplasty, Transluminal, Percutaneous Coronary · Coronary Restenosis · Female · Genetic Predisposition to Disease · Genotype · Humans · Inflammation · Interleukin-10 · Male · Middle Aged · Polymorphism, Genetic · Promoter Regions (Genetics) · Prospective Studies · Risk Factors · Treatment Outcome
[Abstract]

11 Identification of an urinary metabolite profile associated with osteoarthritis
article 2005    
Author: Lamers, R.J.A.N. · Nesselrooij, J.H.J. van · Kraus, V.B. · Jordan, J.M. · Renner, J.B. · Dragomir, A.D. · Luta, G. · Greef, J. van der · Groot, J. de
Keywords: Biomedical Research · 1H NMR spectroscopy · Biomarker · Multivariate data analysis · Osteoarthritis · biological marker · adult · aged · animal experiment · animal model · article · bone density · bone radiography · controlled study · correlation analysis · disease marker · disease severity · dual energy X ray absorptiometry · female · geriatric disorder · guinea pig · hip osteoarthritis · hip radiography · human · knee osteoarthritis · knee radiography · major clinical study · male · metabolite · multivariate analysis · nonhuman · nuclear magnetic resonance spectroscopy · priority journal · regression analysis · United States · urinalysis · Aged · Aged, 80 and over · Biological Markers · Case-Control Studies · Female · Humans · Joints · Least-Squares Analysis · Magnetic Resonance Spectroscopy · Male · Middle Aged · Osteoarthritis
[Abstract]

12 Decreased carotenoid concentrations due to dietary sucrose polyesters do not affect possible markers of disease risk in humans
article 2003    
Author: Broekmans, W.M.R. · Klöpping-Ketelaars, I.A.A. · Weststrate, J.A. · Tijburg, L.B.M. · Poppel, G. van · Vink, A.A. · Berendschot, T.T.J.M. · Bots, M.L. · Castenmiller, W.A.M. · Kardinaal, A.F.M.
Keywords: Health Nutrition · Physiological Sciences · Biomarkers · Carotenoids · Humans · Sucrose polyesters · alpha carotene · alpha tocopherol · beta carotene · beta cryptoxanthin · biological marker · carotenoid · cryptoxanthin · lipid · lycopene · placebo · sucrose polyester · unclassified drug · vitamin · xanthophyll · zeaxanthin · adult · article · cardiovascular performance · clinical trial · controlled clinical trial · controlled study · diagnostic value · dietary intake · disease marker · double blind procedure · energy consumption · eye disease · fat intake · female · food intake · food preference · fruit · habit · human · immune status · lipid blood level · long term care · major clinical study · male · obesity · oxidative stress · physical disease · randomized controlled trial · risk assessment · risk factor · United States · vegetable · vitamin blood level · Adolescent · Adult · Aged · alpha-Tocopherol · beta Carotene · Body Weight · Cardiovascular Diseases · Carotenoids · Dietary Fats, Unsaturated · Double-Blind Method · Endothelium, Vascular · Eye Diseases · Fatty Acids · Female · Health Status · Humans · Immunity · Lipid Peroxidation · Lipids · Macula Lutea · Male · Middle Aged · Patient Compliance · Placebos · Risk Factors · Sucrose · Xanthophylls
[Abstract]

13 Do aberrant crypt foci have predictive value for the occurrence of colorectal tumours? Potential of gene expression profiling in tumours
article 2004    
Author: Wijnands, M.V.W. · Erk, M.J. van · Doornbos, R.P. · Krul, C.A.M. · Woutersen, R.A.
Keywords: Biology · Analytical research · AC, aberrant crypt · ACF, aberrant crypt focus · AIN, American Institute of Nutrition · ANOVA, analysis of variance · AOM, azoxymethane · BIT, benzyl isothiocyanate · CA2, carbonic anhydrase II · CDK4, cyclin-dependent kinase 4 · cDNA, complementary DNA · benzyl isothiocyanate · curcumin · rutoside · animal experiment · animal model · animal tissue · antineoplastic activity · article · carcinogenesis · colorectal tumor · controlled study · correlation analysis · crypt cell · dietary intake · disease marker · drug effect · gene expression profiling · intestine crypt · male · nonhuman · oncogene · prediction · protein expression · rat · scoring system · statistical significance · time series analysis · wheat bran · Animals · Anticarcinogenic Agents · Body Weight · Colorectal Neoplasms · Diet · DNA Primers · DNA, Complementary · Eating · Energy Metabolism · Gene Expression Profiling · Gene Expression Regulation, Neoplastic · Intestinal Mucosa · Male · Predictive Value of Tests · Rats · Rats, Inbred F344 · Reverse Transcriptase Polymerase Chain Reaction · RNA, Neoplasm · Survival Analysis · Tissue Inhibitor of Metalloproteinase-1 · Tumor Markers, Biological · Triticum aestivum
[Abstract]

14 Tumor necrosis factor-α plays an important role in restenosis development
article 2005    
Author: Monraats, P.S. · Pires, N.M.M. · Schepers, A. · Agema, W.R.P. · Boesten, L.S.M. · Vries, M.R. de · Zwinderman, A.H. · Maat, M.P.M. de · Doevendans, P.A.F.M. · Winter, R.J. de · Tio, R.A. · Waltenberger, J. · Hart, L.M. 't · Frants, R.R. · Quax, P.H.A. · Vlijmen, B.J.M. van · Havekes, L.M. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology Health · Biomedical Research · Haplotype · TNFα · Transgenic mice · Apolipoprotein E3 · Messenger RNA · Thalidomide · Tumor necrosis factor alpha · Adult · Aged · Angiography · Animal experiment · Animal model · Clinical practice · Disease marker · Drug delivery system · Genetic polymorphism · Heredity · Knockout mouse · Nonhuman · Percutaneous coronary intervention · Restenosis · Risk assessment · Screening · Aged · Alleles · Angina Pectoris · Angiography · Angioplasty, Transluminal, Percutaneous Coronary · Animals · Constriction, Pathologic · Coronary Angiography · Coronary Disease · Coronary Restenosis · Disease Models, Animal · Female · Femoral Artery · Gene Expression Regulation, Neoplastic · Genetic Predisposition to Disease · Genotype · Haplotypes · Humans · Inflammation · Ischemia · Linkage Disequilibrium · Male · Mice · Mice, Knockout · Mice, Transgenic · Middle Aged · Multivariate Analysis · Odds Ratio · Polymorphism, Genetic · Regression Analysis · Reverse Transcriptase Polymerase Chain Reaction · Risk Factors · RNA, Messenger · Thalidomide · Treatment Outcome · Tumor Necrosis Factor-alpha · Up-Regulation · Animalia · Mus musculus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 14 of 14 found. | Sort by date