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1 A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo
article 2009    
Author: Kienhuis, A.S. · Poll, M.C.G. van de · Jong, C.H.C. de · Gottschalk, R. · Herwijnen, M. van · Boorsma, A. · Kleinjans, J.C.S. · Stierum, R.H. · Delft, J.H.M. van
Keywords: Biology · Biomedical Research · Coumarin · Gene expression profiling · Hepatotoxicity · Parallelogram approach · Primary human hepatocytes · Species difference · Toxicogenomics · Coumarin · Adult · Aged · Blood clotting · Concentration response · Controlled study · Disorders of mitochondrial functions · Down regulation · Energy consumption · Female · Gene expression profiling · Genomics · Human · Human cell · Liver cell · Liver toxicity · Male · Species difference · Toxicogenetics · Transcriptomics · Animalia · Rattus
[Abstract]

2 Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet
article 2015    
Author: Derous, D. · Kelder, T. · Schothorst, E.M. van · Erk, M. van · Voigt, A. · Klaus, S. · Keijer, J. · Radonjic, M.
Keywords: Adipose tissue · Data integration · High-fat diet · Network analysis · Systems biology · Transcriptional regulation · Transcriptomics · Transforming growth factor beta · Adaptation · Analytic method · Animal tissue · Caloric intake · Cell respiration · Controlled study · Disorders of mitochondrial functions · Down regulation · Epididymis fat · Gene expression · Immune response · Lipid diet · Low fat diet · Male · Metabolic regulation · Mouse · Network analysis · Nonhuman · Organ weight · Signal transduction · Stress · Transcription regulation · White adipose tissue · Murinae · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
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