Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date

1 On the antifungal mode of action of metalaxyl, an inhibitor of nucleic acid synthesis in Pythium splendens
article 1981    
Author: Kerkenaar, A.
Keywords: Biology · Metalaxyl · Mithramycin · Radioisotope · Animal experiment · Bisbenzimide h 3 · Cytotoxicity · Dna synthesis · Drug absorption · Drug mechanism · Fungus · Heredity · Histology · Lipogenesis · Metalaxyl c 14 · Nucleic acid synthesis · Oomycetes · Protein synthesis · Rna synthesis
[Abstract]

2 Safety evaluation of synthetic β-carotene
article 1999    
Author: Woutersen, R.A. · Wolterbeek, A.P.M. · Appel, M.J. · Berg, H. van den · Goldbohm, R.A. · Feron, V.J.
Keywords: Toxicology · Absorption · Cancer prevention · Distribution · Lung cancer · Toxicity · beta carotene · cancer risk · carcinogenicity · chronic toxicity · drug absorption · drug distribution · drug safety · drug transport · genotoxicity · human · nonhuman · reproductive toxicity · review · toxicity testing · Absorption · Animals · Antioxidants · beta Carotene · Cell Transformation, Neoplastic · Chemoprevention · Drug Interactions · Humans · Intervention Studies · Lung Neoplasms · Mice · Rats · Rats, Sprague-Dawley · Skin Neoplasms · Smoking · Animalia
[Abstract]

3 Differences in uptake of adriamycin and daunomycin by normal BM cells and acute leukemia cells determined by flow cytometry
article 1981    
Author: Sonneveld, P. · Engh, G.J. van den
Keywords: Pharmacology · Acute leukemia · Animal experiment · Blood and hemopoietic system · Drug absorption · Drug comparison · Flow cytometry · Granulocyte · Human cell · In vitro study · Lymphatic system · Lymphoblast · Myeloblast · Pharmacokinetics · Acute Disease · Animal · Bone Marrow · Bone Marrow Cells · Colony-Forming Units Assay · Daunorubicin · Doxorubicin · Fluorometry · Hematopoietic Stem Cells · Human · Leukemia · Lymphocytes · Rats
[Abstract]

4 Percutaneous absorption of mexoryl SX® in human volunteers: Comparison with in vitro data
article 2003    
Author: Benech-Kieffer, F. · Meuling, W.J.A. · Leclerc, C. · Roza, L. · Leclaire, J. · Nohynek, G.
Keywords: Nutrition Health · Physiological Sciences · Human skin · Mass balance · Mexoryl SX® · Percutaneous absorption · Sunscreen · carbon 14 · mexoryl sr · sulfonic acid derivative · sunscreen · terephthalylidene dicamphor sulfonic acid · unclassified drug · adult · article · blood sampling · correlation analysis · dermis · drug absorption · drug exposure · feces analysis · human · human experiment · human tissue · in vitro study · male · normal human · priority journal · radioactivity · single drug dose · skin absorption · skin surface · urinalysis · Administration, Topical · Adult · Bornanes · Camphor · Diffusion · Diffusion Chambers, Culture · Half-Life · Humans · Male · Mesylates · Skin Absorption · Sulfonic Acids · Sunscreening Agents
[Abstract]

5 Dermatokinetics of didecyldimethylammonium chloride and the influence of some commercial biocidal formulations on its dermal absorption in vitro
article 2007    
Author: Buist, H.E. · Heer, C. de · Burgsteden, J.A. van · Sandt, J.J.M. van de
Keywords: Chemistry · Biomedical Research · Biocides · Dermal absorption · Dermatokinetics · Didecyldimethylammonium chloride · Quaternary ammonium chlorides · Repeated exposure · Risk assessment · Single exposure · Skin barrier · Vehicle effects · Aldehyde · Biocide · Didecyldimethylammonium chloride · Adult · Aqueous solution · Concentration (parameters) · Correlation analysis · Drug absorption · Drug distribution · Drug exposure · Drug formulation · Drug penetration · Epidermis · Female · Human · Human cell · Human tissue · In vitro study · Priority journal · Skin absorption · Skin permeability · Stratum corneum · Toxicokinetics · Administration, Cutaneous · Cells, Cultured · Chemistry, Pharmaceutical · Disinfectants · Humans · Kinetics · Permeability · Quaternary Ammonium Compounds · Skin Absorption · Tissue Distribution
[Abstract]

6 Intravenous and inhalation toxicokinetics of sarin stereoisomers in atropinized guinea pigs
article 2000    
Author: Spruit, W.E.T. · Langenberg, J.P. · Trap, H.C. · Wiel, H.J. van der · Helmich, R.B. · Helden, H.P.M. van · Benschop, H.P.
Keywords: Acetylcholinesterase inhibition · Guinea pig · Intravenous bolus · Nose-only exposure · Respiratory parameters · Stereoisomers · Toxicokinetics · Animal experiment · Animal model · Binding site · Chemical warfare · Controlled study · Drug absorption · Drug elimination · Enzyme inhibition · Gas chromatography · Guinea pig · Nonhuman · Nose mucosa · Stereoisomerism · Toxicokinetics · Acetylcholinesterase · Administration, Inhalation · Animals · Area Under Curve · Atropine · Chemical Warfare Agents · Guinea Pigs · Injections, Intravenous · Male · Stereoisomerism · Acetylcholinesterase, EC 3.1.1.7 · Atropine, 51-55-8 · Chemical warfare agents · Sarin, 107-44-8
[Abstract]

7 Absorption enhancement, structural changes in tight junctions and cytotoxicity caused by palmitoyl carnitine in Caco-2 and IEC-18 cells
article 1998    
Author: Duizer, E. · Wulp, C. van der · Versantvoort, C.H.M. · Groten, J.P.
Keywords: Nutrition · Lactate dehydrogenase · Palmitoylcarnitine · Propidium iodide · Apical membrane · Cell membrane · Cell strain caco 2 · Cell viability · Controlled study · Drug absorption · Drug cytotoxicity · Drug transport · Electric resistance · Human · Human cell · Image processing · Intestine absorption · Macromolecule · Oral drug administration · Priority journal · Protein localization · Tight junction · Animals · Biological Transport · Caco-2 Cells · Cell Survival · Dose-Response Relationship, Drug · Egtazic Acid · Electric Impedance · Humans · Immunohistochemistry · Intestinal Absorption · Membrane Proteins · Octoxynol · Palmitoylcarnitine · Phosphoproteins · Rats · Tight Junctions
[Abstract]

8 A randomized three-way cross-over study in healthy pituitary-suppressed women to compare the bioavailability of human chorionic gonadotrophin (Pregnyl®) after intramuscular and subcutaneous administration
article 1998    
Author: Mannaerts, B.M.J.L. · Geurts, T.B.P. · Odink, J.
Keywords: Nutrition · Bioequivalence · Human chorionic gonadotrophin · Intramuscular · Pharmacokinetics · Subcutaneous · Chorionic gonadotropin · Adult · Area under the curve · Bioequivalence · Clinical trial · Controlled study · Dose response · Drug absorption · Drug bioavailability · Drug blood level · Drug elimination · Drug half life · Female · Human · Human experiment · Hypopituitarism · Intramuscular drug administration · Normal human · Randomized controlled trial · Subcutaneous drug administration · Administration, Oral · Adolescent · Adult · Chorionic Gonadotropin · Contraceptives, Oral · Cross-Over Studies · Dose-Response Relationship, Drug · Female · Humans · Injections, Intramuscular · Pituitary Gland
[Abstract]

9 Oligofructose stimulates calcium absorption in adolescents
article 1999    
Author: Heuvel, E.G.H.M. van den · Muys, T. · Dokkum, W. van · Schaafsma, G.
Keywords: Nutrition · Double stable- isotope technique · Male adolescents · Nondigestible oligosaccharides · Oligofructose · True calcium absorption · Calcium · Fructose · Oligosaccharide · Stable isotope · Adolescent · Calcium absorption · Calcium metabolism · Clinical research · Clinical trial · Controlled clinical trial · Controlled study · Crossover procedure · Dietary intake · Double blind procedure · Drug absorption · Human · Human experiment · Intravenous drug administration · Male · Normal human · Oral drug administration · Randomized controlled trial · Urinalysis · Urinary excretion · Administration, Oral · Adolescent · Analysis of Variance · Calcium · Cross-Over Studies · Double-Blind Method · Fructose · Humans · Injections, Intravenous · Intestinal Absorption · Male · Sucrose
[Abstract]

10 A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices
article 2014    
Author: Westerhout, J. · Steeg, E. van de · Grossouw, D. · Zeijdner, E.E. · Krul, C.A.M. · Verwei, M. · Wortelboer, H.M.
Keywords: Biology · Caco-2 · Food-effect · Human intestine · Intestinal absorption · InTESTine™ · Porcine intestine · Acebutolol · Atenolol · Candesartan · Cetirizine · Cimetidine · Ciprofloxacin · Diazepam · Digoxin · Famotidine · Hydrocortisone · Ibuprofen · Indometacin · Mannitol · Melagatran · Metoprolol · Mucin · Oxprenolol · Phenazone · Pindolol · Propranolol · Ranitidine · Salazosulfapyridine · Salicylic acid · Testosterone · Verapamil · Active transport · Animal tissue · CACO 2 cell line · Controlled study · Domestic pig · Drug absorption · Drug bioavailability · Drug penetration · Drug transport · Electric resistance · Ex vivo study · Female · Human · Human tissue · Intestine absorption · Intestine mucosa · Male · Nonhuman · Passive transport · Prediction · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

11 In vitro models for the prediction of in vivo performance of oral dosage forms
article 2014    
Author: Kostewicz, E.S. · Abrahamsson, B. · Brewster, M. · Brouwers, J. · Butler, J. · Carlert, S. · Dickinson, P.A. · Dressman, J. · Holm, R. · Klein, S. · Mann, J. · McAllister, M. · Minekus, M. · Muenster, U. · Müllertz, A. · Verwei, M. · Vertzoni, M. · Weitschies, W. · Augustijns, P.
Keywords: Biology · Biorelevant · In vitro evaluation · In vivo biopharmaceutical performance · Innovative Medicines Initiative (IMI) · Oral Biopharmaceutical Tools (OrBiTo) · Oral drug formulations · Albendazole · Amprenavir · Bile acid · Celecoxib · Cinnarizine · Cyclodextrin · Danazol · Diclofenac · Dipyridamole · Excipient · Gelucire · Ketoconazole · Loviride · Montelukast · Octanol · Propranolol · Saquinavir · Controlled drug release · Drug absorption · Drug bioavailability · Drug development · Drug dosage form · Drug formulation · Drug penetration · Drug solubility · Gastrointestinal motility · Human · Hydrodynamics · In vitro study · In vivo study · Lipolysis · Nonhuman · Precipitation · Prediction · Priority journal · Quality control · Review · Simulation · Tablet disintegration · Food and Nutrition · Healthy Living · Life · PHS - Pharmacokinetics & Human Studies · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Physicochemical properties and transport of steroids across Caco-2 cells
article 2003    
Author: Faassen, F. · Kelder, J. · Lenders, J. · Onderwater, R. · Vromans, H.
Keywords: Drugs · Physiological Sciences · Absorption · Caco-2 permeability · Physicochemical properties · Steroids · 17alpha hydroxy 11 methylene 19 norpregna 4,15 dien 20 yn 3 one · aldosterone · cefalexin · cortisone · dexamethasone · estradiol · ethinylestradiol · etonogestrel · gestodene · glucose · hydrocortisone · macrogol 4000 · mannitol · nandrolone · norethisterone · norgestrel · org 32540 · org 34694 · org 36410 · org 4060 · org 4325 · org om 08 · phenazone · prednisolone · progesterone · spironolactone · steroid · testosterone · verapamil · article · calculation · cell membrane permeability · cell strain CACO 2 · controlled study · drug absorption · drug surveillance program · drug transport · human · human cell · molecular weight · physical chemistry · priority journal · Biological Transport · Caco-2 Cells · Chemistry, Physical · Humans · Solubility · Steroids
[Abstract]

13 Cholecystokinin regulates satiation independently of the abdominal vagal nerve in a pig model of total subdiaphragmatic vagotomy
article 2015    
Author: Ripken, D. · Wielen, N. van der · Meulen, J. van der · Schuurman, T. · Witkamp, R.F. · Hendriks, H.F.J. · Koopmans, S.J.
Keywords: Biology · Cholecystokinin · Devazepide · Exendin (9-39) · Food intake regulation · Glucagon-like peptide 1 · Vagal nerve · Cholecystokinin · Cholecystokinin A receptor · Glucagon like peptide 1 · Glucagon like peptide 1 receptor · Glucose · Insulin · Paracetamol · Abdominal vagal nerve · Animal experiment · Animal model · Animal tissue · Autopsy · Cholecystokinin blood level · Controlled study · Drug absorption · Drug blood level · Fluid intake · Food intake · Glucose blood level · Hormonal regulation · Hormone response · Insulin blood level · Intestine motility · Male · Maximum plasma concentration · Nonhuman · Postprandial state · Patiety · Sham procedure · Stomach absorption · Stomach content · Stomach emptying · Subdiaphragmatic vagotomy · Time to maximum plasma concentration · Vagotomy · Vagus nerve · Weight gain · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

14 A dynamic artificial gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions
article 2004    
Author: Blanquet, S. · Zeijdner, E. · Beyssac, E. · Meunier, J.-P. · Denis, S. · Havenaar, R. · Alric, M.
Keywords: Pharmacology Biology · Physiological Sciences · Dissolution profile · Gastrointestinal model · Oral formulations · Paracetamol · Probiotics · bacilor · bile salt · pancreatin · paracetamol · pepsin A · probiotic agent · starch · triacylglycerol lipase · unclassified drug · article · bacterial survival · bile secretion · body temperature · computer simulation · drug absorption · drug delivery system · drug dosage form · drug formulation · drug solubility · food intake · gastrointestinal tract · gastrointestinal transit · in vitro study · Lactobacillus casei · pancreas secretion · peristalsis · pH · priority journal · salivation · small intestine · stomach · stomach secretion · Acetaminophen · Administration, Oral · Digestive System · Dosage Forms · Gastrointestinal Transit · Models, Biological · Predictive Value of Tests
[Abstract]

15 Recent methodology in the phytochemical analysis of ginseng
article 2008    
Author: Angelova, N. · Kong, H.-W. · Heijden, R. van de · Yang, S.-Y. · Choi, Y.H. · Kim, H.K. · Wang, M. · Hankemeier, T. · Greef, J. van der · Xu, G. · Verpoorte, R.
Keywords: Health · Biomedical Research · Ginsenosides · Mass spectrometry · Metabolomics · Panax ginseng · Ginseng extract · Phenol · Saponin · Analytic method · Antineoplastic activity · Biosensor · Drug absorption · Drug determination · Drug distribution · Drug efficacy · Drug excretion · Drug half life · Drug metabolism · Drug safety · Drug structure · Electrospray mass spectrometry · Enzyme linked immunosorbent assay · Fourier transform mass spectrometry · Ginseng · High performance liquid chromatography · Human · Immunoregulation · Ion cyclotron resonance mass spectrometry · Liquid chromatography · Liver protection · Mass spectrometry · Metabolomics · Near infrared reflectance spectroscopy · Nonhuman · Nuclear magnetic resonance spectroscopy · Plant root · Quality control · Review · Sensitivity analysis · Structure analysis · Systems biology · Drugs, Chinese Herbal · Ginsenosides · Mass Spectrometry · Panax · Spectroscopy, Fourier Transform Infrared · Spectroscopy, Near-Infrared · Panax ginseng
[Abstract]

16 Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: A mass balance trial
article 2007    
Author: Cawello, W. · Wolff, H.M. · Meuling, W.J.A. · Horstmann, R. · Braun, M.
Keywords: Biomedical Research · carbon 14 · dopamine receptor stimulating agent · rotigotine · silicone · adult · article · clinical trial · diarrhea · dizziness · drug absorption · drug clearance · drug delivery system · drug distribution · drug elimination · drug formulation · drug metabolism · drug penetration · drug release · drug structure · drug tolerability · fatigue · human · human experiment · isotope labeling · liquid chromatography · liquid scintillation counting · male · mass balance · normal human · phase 1 clinical trial · priority journal · radioactivity · single drug dose · tandem mass spectrometry · Administration, Cutaneous · Adolescent · Adult · Carbon Radioisotopes · Chromatography, Liquid · Dopamine Agonists · Humans · Male · Middle Aged · Tandem Mass Spectrometry · Tetrahydronaphthalenes · Thiophenes
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date