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1 Fibrinolysis and calcium [fibrinolyse und kalzium]
article 1984    
Author: Haverkate, F. · Nieuwenhuizen, W.
Keywords: calcium · calcium chloride · citric acid · edetic acid · blood and hemopoietic system · blood clotting · drug efficacy · drug therapy · fibrinolysis · human · short survey · therapy
[Abstract]

2 Putting pharmacogenetics into practice
article 2006    
Author: Hopkins, M.M. · Ibarreta, D. · Gaisser, S. · Enzing, C.M. · Ryan, J. · Martin, P.A. · Lewis, G. · Detmar, S. · Akker-van Marle, M.E. van den · Hedgecoe, A.M. · Nightingale, P. · Dreiling, M. · Hartig, K.J. · Vullings, W. · Forde, T.
Keywords: Health · c=Clinical practice · Drug efficacy · Drug response · Drug safety · Health care system · Pharmacogenomics · Policy · Review · Vocational education · Biotechnology · Drug Approval · Drug Design · Drug Industry · Pharmacogenetics · Research · United States

3 Vaccinatie tegen bof succesvol [A successful vaccine against mumps]
article 1993    
Author: Hirasing, R.A. · Schaapveld, K.
Keywords: Health · Mumps vaccine · Controlled study · Drug efficacy · Immunization · Major clinical study · Preventive medicine · Short survey · Vaccination · Adolescent · Adult · Child · Child, Preschool · Female · Human · Infant · Male · Meningitis, Viral · Mumps · Mumps Vaccine · Netherlands · Orchitis

4 A moderate fish intake increases plasminogen activator inhibitor type-1 in human volunteers
article 1989    
Author: Emeis, J.J. · Houwelingen, A.C. van · Hoogen, C.M. van den · Hornstra, G.
Keywords: Plasminogen activator inhibitor 1 · Controlled study · Drug efficacy · Human experiment · Normal human · Acute-Phase Proteins · Adult · Animal · Diet · Fibrinolysis · Fishes · Glycoproteins · Human · Male · Meat · Plasminogen Activators · Plasminogen Inactivators · Support, Non-U.S. Gov't · Time Factors
[Abstract]

5 Acetazolamide improves cerebral oxygenation during exercise at high altitude
article 2006    
Author: Vuyk, J. · Bos, J. van den · Terhell, K. · Bos, R. de · Vletter, A. · Valk, P. · Beuzekom, M. van · Kleef, J. van · Dahan, A.
Keywords: Pharmacology · Acclimatization · Acute mountain sickness · BIS · Lake Louise score · Near-infrared spectroscopy (NIRS) · Psychomotor function · altitude acclimatization · China · Drug efficacy · Heart rate · Mountaineering · Near infrared spectroscopy · Psychomotor activity · Psychomotor performance · Acetazolamide · Acute Disease · Altitude Sickness · Analysis of Variance · Brain · Carbonic Anhydrase Inhibitors · Cerebrovascular Circulation · Exercise · Motor Activity · Oxygen Consumption · Reference Values
[Abstract]

6 Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development
article 2006    
Author: Greef, J. van der · Adourian, A. · Muntendam, P. · McBurney, R.N.
Keywords: Biology · Analytical research · biological marker · drug metabolite · new drug · bioinformatics · body fluid · data base · decision making · drug determination · drug efficacy · drug marketing · drug research · drug safety · human · medical technology · metabolomics · multiple sclerosis · non insulin dependent diabetes mellitus · nonhuman · osteoarthritis · phenotype · postmarketing surveillance · proteomics · review · serology · structure activity relation
[Abstract]

7 Contrasting responses to interferon β-1b treatment in relapsing-remitting multiple sclerosis: Does baseline interleukin- 12p35 messenger RNA predict the efficacy of treatment?
article 2000    
Author: Boxel van-Dezaire, A.H.H. · Trigt van-Hoff, S.C.J. · Killestein, J. · Schrijver, H.M. · Houwelingen, J.C. van · Polman, C.H. · Nagelkerken, L.
Keywords: Health · Gamma interferon · Interferon beta serine · Interleukin 10 · Interleukin 12 · Interleukin 12 receptor · Interleukin 18 · Messenger RNA · Protein p35 · Protein p40 · Clinical article · Disability · Disease classification · DNA synthesis · Drug efficacy · Gene expression · Multiple sclerosis · Prediction · Rating scale · Recurrent disease · Treatment outcome · Adult · Female · Humans · Interferon-beta · Interleukin-12 · Male · Multiple Sclerosis, Relapsing-Remitting · Predictive Value of Tests · RNA, Messenger · Time Factors
[Abstract]

8 Pharmacokinetics of carboplatin with and without amifostine in patients with solid tumors
article 1997    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Eeltink, C.M. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Pharmacology · Amifostine · Carboplatin · Adult · Blood sampling · Clinical article · Clinical trial · Controlled clinical trial · Creatinine blood level · Creatinine clearance · Drug blood level · Drug efficacy · Drug half life · Enzyme linked immunosorbent assay · Female · Human · Intravenous drug administration · Male · Phase 1 clinical trial · Solid tumor · Amifostine · Animals · Antineoplastic Agents · Carboplatin · Dose-Response Relationship, Drug · Half-Life · Kidney · Kidney Function Tests · Metabolic Clearance Rate · Mice · Mice, Nude · Neoplasms
[Abstract]

9 Bispecific monoclonal antiboldies increase the fibrin-specific fibrinolytic activity of tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA)
article 1992    
Author: Bos, R. · Nieuwenhuizen, W.
Keywords: Health · fibrin · monoclonal antibody · plasminogen activator · tissue plasminogen activator · urokinase · drug carrier · cell fusion · conference paper · drug binding · drug efficacy · drug megadose · endothelium cell · enzyme activity · fibrinolysis · fibrinolytic therapy · hybridoma · plasminogen activation · antibody specificity · drug effect · immunology · metabolism · Antibodies, Monoclonal · Antibody Specificity · Drug Carriers · Fibrin · Fibrinolysis · Human · Kinetics · Plasminogen Activator Inhibitor 1 · Tissue Plasminogen Activator · Urinary Plasminogen Activator

10 The influence of radiotherapy and chemotherapy on the vitamin status of cancer patients
article 1985    
Author: Schreurs, W.H.P. · Odink, J. · Egger, R.J. · Wedel, M. · Bruning, P.F.
Keywords: Antineoplastic agent · Bladder · Blood and hemopoietic system · Cancer combination chemotherapy · Clinical article · Drug efficacy · Hodgkin disease · Human · Intravenous drug administration · Male genital system · Priority journal · Therapy · Ascorbic Acid · Bladder Neoplasms · Calcifediol · Female · Human · Lymphoma · Male · Neoplasms · Prostatic Neoplasms · Uterine Neoplasms · Vitamin A · Vitamin B 12 · Vitamin E · Vitamins
[Abstract]

11 Usefulness of temazepam and zaleplon to induce afternoon sleep
article 2006    
Author: Simons, M. · Koerhuis, C.L. · Valk, P.J.L. · Oord, M.H.A.H. van den
Keywords: Defence · hypnotic agent · placebo · temazepam · zaleplon · adult · alertness · clinical trial · cognition · controlled clinical trial · controlled study · crossover procedure · double blind procedure · drug efficacy · drug safety · fatigue · human · human experiment · male · military service · muscle strength · night · human performance · quality control · shift worker · sleep induction · somnolence · Acetamides · Attention · Benzodiazepines · drugs · sleep · chronobiology · military
[Abstract]

12 Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin
article 2015    
Author: Kühnast, S. · Tuin, S.J.L. van der · Hoorn, J.W.A. van der · Klinken, J.B. van · Simic, B. · Pieterman, E. · Havekes, L.M. · Landmesser, U. · Lüscher, T.F. · Dijk, K.W. van · Rensen, P.C.N. · Jukema, J.W. · Princen, H.M.G.
Keywords: Biology · Anacetrapib · Atherosclerosis · Atorvastatin · Cholesteryl ester transfer protein · HDL function · HDL-cholesterol · Non-HDL-cholesterol · Apolipoprotein E3 · Atorvastatin · High density lipoprotein cholesterol · Analysis of covariance · Animal cell · Animal model · Aorta atherosclerosis · Aorta root · Atherosclerotic plaque · Cholesterol blood level · Controlled study · Diet · Disease severity · Drug efficacy · Drug potentiation · Enzyme activity · Female · In vivo study · Mouse · Nonhuman · Risk reduction · Treatment duration · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

13 Melphalan antitumor efficacy and hepatotoxicity: The effect of variable infusion duration in the hepatic artery
article 2003    
Author: Rothbarth, J. · Woutersen, R.A. · Sparidans, R.W. · Velde, C.J.H. van de · Mulder, G.J.
Keywords: Toxicology · Toxicology and Applied Pharmacology · melphalan · animal cell · animal experiment · animal model · animal tissue · antineoplastic activity · article · biliary tract fibrosis · body weight · colon tumor · controlled study · drug efficacy · drug infusion · drug liver level · drug tumor level · hepatic artery · high performance liquid chromatography · liver metastasis · liver perfusion · liver toxicity · nonhuman · priority journal · rat · Animals · Antineoplastic Agents, Alkylating · Disease Models, Animal · Hepatic Artery · Infusions, Intra-Arterial · Liver Neoplasms · Male · Melphalan · Neoplasm Transplantation · Rats · Treatment Outcome
[Abstract]

14 Betaine supplementation lowers plasma homocysteine in healthy men and women
article 2003    
Author: Steenge, G.R. · Verhoef, P. · Katan, M.B.
Keywords: Health · Physiological Sciences · Betaine · Folic acid · Homocysteine metabolism · Intervention study · Methionine-loading test · 5 methyltetrahydrofolic acid · betaine · homocysteine · methionine · placebo · adult · amino acid blood level · amino acid metabolism · area under the curve · article · body mass · cardiovascular disease · cardiovascular risk · clinical trial · controlled clinical trial · controlled study · diet restriction · diet supplementation · drug efficacy · female · human · loading test · male · randomized controlled trial · Adult · Betaine · Blood Glucose · Blood Pressure · Body Mass Index · Diet · Dietary Supplements · Eating · Fasting · Female · Folic Acid · Homocysteine · Humans · Lipids · Male · Reference Values
[Abstract]

15 Randomized controlled trial assessing a traditional Chinese medicine remedy in the treatment of primary dysmenorrhea
article 2006    
Author: Kennedy, S. · Jin, X. · Yu, H. · Zhong, S. · Magill, P. · Vliet, T. van · Kistemaker, C. · Voors, C. · Pasman, W.
Keywords: Health · Analytical research · Biomedical research · Angelica sinensis extract · Corydalis yanhusuo extract · ibuprofen · Paeonia lactiflora extract · placebo · plant extract · unclassified drug · adult · Angelica sinensis · article · Chinese medicine · clinical article · clinical trial · controlled clinical trial · controlled study · Corydalis · disease duration · double blind procedure · drug efficacy · drug safety · dysmenorrhea · female · headache · human · Paeonia · patient compliance · priority journal · randomization · randomized controlled trial · tablet · visual analog scale · Adolescent · Adult · Drugs, Chinese Herbal · Dysmenorrhea · Female · Humans · Medicine, Chinese Traditional · Middle Aged · Pilot Projects · Placebo Effect · Treatment Outcome
[Abstract]

16 Thrombolytic properties in a rabbit jugular vein thrombosis model of a tissue-type plasminogen activator mutant lacking the growth factor- and kringle 1-domains
article 1992    
Author: Emeis, J.J. · Verheijen, J.H.
Keywords: Biology · Alpha 2 antiplasmin · Alteplase · Fk 2p · Gowth factor · Plasminogen · Unclassified drug · Animal experiment · Animal model · Blood clot lysis · Conference paper · Dose response · Dose time effect relation · Drug efficacy · Fibrinogen blood level · Intravenous drug administration · Mutant · Nonhuman · Protein domain · Spectrophotometry · Vein thrombosis · Animal · Comparative Study · Fibrinolysis · Infusions, Intravenous · Injections, Intravenous · Jugular Veins · Metabolic Clearance Rate · Rabbits · Recombinant Proteins · Thrombosis · Tissue Plasminogen Activator · Animalia · Oryctolagus cuniculus
[Abstract]

17 Het instellen op insuline van patiënten met diabetes mellitus type 2: In een transmurale organisatievorm minstens even effectief als poliklinisch; een retrospectief onderzoek met 4 jaar follow-up [Initiating insulin therapy in patients with diabetes mellitus type 2: In a transmural form of care at least as effective as an outpatients form; a retrospective study with a 4-year follow-up]
article 2002    
Author: Rosendal, H. · Vondeling, H. · Witte, L.P. de · Hutubessy, R.C.W. · Beekum, W.T. van · Heine, R.J.
Keywords: Health · Hemoglobin A1c · Adult · Controlled study · Diabetes control · Drug efficacy · Glucose blood level · Health behavior · Health status · Hemoglobin determination · Insulin treatment · Major clinical study · Non insulin dependent diabetes mellitus · Outpatient care · Patient care · Patient monitoring · Aged · Ambulatory Care Facilities · Clinical Protocols · Cohort Studies · Diabetes Mellitus, Type 2 · Family Practice · Female · Follow-Up Studies · Humans · Hypoglycemic Agents · Insulin · Male · Middle Aged · Netherlands · Outcome Assessment (Health Care) · Patient Satisfaction · Retrospective Studies · Self Care · Treatment Outcome
[Abstract]

18 Cholesteryl ester transfer protein inhibition: Effect on reverse cholesterol transport?
article 2006    
Author: Rensen, P.C.N. · Havekes, L.M.
Keywords: Biology · Biomedical Research · 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester · Atorvastatin · Cholesterol ester transfer protein inhibitor · Fibric acid derivative · High density lipoprotein cholesterol · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Nicotinic acid · Torcetrapib · Atherosclerosis · Cholesterol transport · Clinical trial · Drug efficacy · Drug mechanism · Dyslipidemia · Editorial · Ischemic heart disease · Nonhuman · Plasma clearance · Protein expression · Reverse cholesterol transport · Animals · Biological Transport · Cardiovascular Diseases · Carrier Proteins · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Glycoproteins · Humans · Lipid Metabolism · Lipoproteins, HDL · Rabbits · Risk Factors
[Abstract]

19 Lung damage in the rat after irradiation and treatment with cytotoxic drugs
article 1986    
Author: Varekamp, A.E. · Vries, A.J. de · Hagenbeek, A.
Keywords: cyclophosphamide · cytarabine · cytotoxic agent · animal experiment · animal model · drug cytotoxicity · drug efficacy · histology · interstitial pneumonia · intoxication · intraperitoneal drug administration · intravenous drug administration · irradiation · lung function · lung injury · methodology · nonhuman · radiation injury · respiratory system · breathing · drug effect · LD 50 · pathophysiology · radiation exposure · radiation response · rat strain · Animal · Cyclophosphamide · Cytarabine · Dose-Response Relationship, Drug · Dose-Response Relationship, Radiation · Female · Lethal Dose 50 · Lung · Rats · Rats, Inbred Strains · Respiration
[PDF] [Abstract]

20 Effect of cigarette-smoke condensate and norharman on the induction of SCEs by direct and indirect mutagens in CHO cells
article 1986    
Author: Rutten, A.A.J.J.L. · Wilmer, J.W.G.M.
Keywords: Nutrition · 2 Aminoanthracene · 2 Fluorenylamine · Benzo[a]pyrene · Beta carboline · Cyclophosphamide · Fluorenylacetohydroxamic acid · Methylnitronitrosoguanidine · Mitomycin c · N (2 fluorenyl)acetamide · Tobacco smoke · Animal cell · Cell culture · Chemical mutagenesis · Cho cell · Cigarette smoking · Drug efficacy · Drug interaction · Female genital system · Heredity · In vitro study · Methodology · Mutagen testing · Nonhuman · Priority journal · Sister chromatid exchange · Synergism · Topical drug administration · Alkaloids · Animal · Cell Line · Drug Synergism · Hamsters · Harmine · Mutagenicity Tests · Mutagens · Plants, Toxic · Sister Chromatid Exchange · Smoke · Support, Non-U.S. Gov't · Tobacco · Biology · cytology · celleer

Search results also available in MS Excel format.

Showing 1 to 20 of 50 found. Next | Sort by date