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1 Mutagenicity testing of urine from vinylchloride (VCM) treated rats using the salmonella test system
article 1977    
Author: Mattern, I.E. · Zwaan, W.B. van der · Willems, M.J.
Keywords: Biology · Soybean oil · Vinyl chloride · Aerosol · Drug screening · Drug urine level · Inhalational drug administration · Mutagenesis · Oral drug administration · Rat · Salmonella
[Abstract]

2 Pharmacokinetics and bioavailability of dapsone in the beagle dog
article 1989    
Author: Hekman, P. · Rens, P. van · Rietvel, E.C. · Coert, A.
Keywords: Nutrition · Dapsone · Animal experiment · Dog · Drug bioavailability · Drug blood level · Drug determination · Intravenous drug administration · Nonhuman · Oral drug administration · Preliminary communication
[Abstract]

3 Putting pharmacogenetics into practice
article 2006    
Author: Hopkins, M.M. · Ibarreta, D. · Gaisser, S. · Enzing, C.M. · Ryan, J. · Martin, P.A. · Lewis, G. · Detmar, S. · Akker-van Marle, M.E. van den · Hedgecoe, A.M. · Nightingale, P. · Dreiling, M. · Hartig, K.J. · Vullings, W. · Forde, T.
Keywords: Health · c=Clinical practice · Drug efficacy · Drug response · Drug safety · Health care system · Pharmacogenomics · Policy · Review · Vocational education · Biotechnology · Drug Approval · Drug Design · Drug Industry · Pharmacogenetics · Research · United States

4 Criteria to distinguish between natural situations and illegal use of boldenone, boldenone esters and boldione in cattle. 1. Metabolite profiles of boldenone, boldenone esters and boldione in cattle urine
article 2006    
Author: Le Bizec, B. · Courant, F. · Gaudin, I. · Bichon, E. · Destrez, B. · Schilt, R. · Draisci, R. · Monteau, F. · André, F.
Keywords: Biology · Analytical research · Anabolic · Boldenone · Endogenous · 17 Beta boldenone · Biological marker · Boldione · Drug metabolite · Unclassified drug · Animal experiments · Comparative study · Controlled study · Drug abuse · Drug metabolism · Drug urine level · Androstadienes · Cattle · Esters · Gas Chromatography-Mass Spectrometry · Testosterone · Animalia · Bos taurus
[Abstract]

5 Rescuing drug discovery: In vivo systems pathology and systems pharmacology
article 2005    
Author: Greef, J. van der · McBurney, R.N.
Keywords: Pharmacology Health · Analytical research · 5' methoxyhydnocarpin · berberine · biological marker · ginseng extract · herbaceous agent · Hypericum extract · paroxetine · unclassified drug · article · bioinformatics · cardiovascular disease · clinical trial · cost benefit analysis · cost control · cost effectiveness analysis · data base · depression · drug approval · drug design · drug efficacy · drug indication · drug industry · drug information · drug marketing · drug research · drug response · drug safety · drug screening · drug targeting · growth inhibition · health care · health care cost · health program · human · in vivo study · non insulin dependent diabetes mellitus · nonhuman · patient compliance · prediction · prescription · priority journal · productivity · quantitative analysis · standard · system analysis · validation process · animal · diagnosis · economics · mass communication · review · Animals · Cost-Benefit Analysis · Diagnosis · Diffusion of Innovation · Drug Approval · Drug Design · Drug Evaluation · Drug Evaluation, Preclinical · Drug Industry · Humans
[Abstract]

6 Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development
article 2006    
Author: Greef, J. van der · Adourian, A. · Muntendam, P. · McBurney, R.N.
Keywords: Biology · Analytical research · biological marker · drug metabolite · new drug · bioinformatics · body fluid · data base · decision making · drug determination · drug efficacy · drug marketing · drug research · drug safety · human · medical technology · metabolomics · multiple sclerosis · non insulin dependent diabetes mellitus · nonhuman · osteoarthritis · phenotype · postmarketing surveillance · proteomics · review · serology · structure activity relation
[Abstract]

7 Use of biosensors for rapid drug residue analysis without sample deconjugation or clean-up: A possible way forward
article 1998    
Author: Elliott, C.T. · Baxter, G.A. · Hewitt, S.A. · Arts, C.J.M. · Baak, M. van · Hellenäs, K.-E. · Johannson, A.
Keywords: Nutrition · Drug residue · Reagent · Salbutamol · Solvent · Animal experiment · Biosensor · Cattle · Conference paper · Controlled study · Device · Drug conjugation · Drug determination · Drug hydrolysis · Drug urine level · Gas chromatography · Immunoassay · Male · Mass spectrometer · Mass spectrometry · Nonhuman · Oral drug administration · Radioimmunoassay · Adrenergic beta-Agonists · Albuterol · Animals · Biosensing Techniques · Cattle · Drug Residues · Gas Chromatography-Mass Spectrometry · Growth Substances · Immunoassay · Male · Radioimmunoassay · Sensitivity and Specificity
[Abstract]

8 On the in vivo and in vitro interaction of tissue-type plasminogen activator with liver cells
article 1993    
Author: Otter, M.
Keywords: Biology · Tissue plasminogen activator · Animal cell · Animal experiment · Animal tissue · Drug blood level · Drug clearance · Drug receptor binding · Fibrinolysis · Liver cell · Nonhuman · Note · Rat
[Abstract]

9 Modification of the early and late delayed radiation response of the rat spinal cord by chemotherapeutic agents
article 1981    
Author: Kogel, A.J. van der
Keywords: cytarabine · methotrexate · abstract report · animal experiment · central nervous system · intramuscular drug administration · intrathecal drug administration · intravenous drug administration · radiation injury · rat · spinal cord
[Abstract]

10 Categorization of health risks from exposure to active pharmaceutical ingredients = Categorisatie van bereidingsrisico's
article 2005    
Author: Tielemans, E. · Schaafsma, G. · Heer, C. de · Rijnders, E. · Groenewold, M. · Bouwman, Y.
Keywords: Safety Chemistry · Food and Chemical Risk Analysis · pyridoxine derivative · drug contamination · drug exposure · drug manufacture · health hazard · human · maximum allowable concentration · Netherlands · occupational exposure · short survey · toxicity

11 Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: A mass balance trial
article 2007    
Author: Cawello, W. · Wolff, H.M. · Meuling, W.J.A. · Horstmann, R. · Braun, M.
Keywords: Biomedical Research · carbon 14 · dopamine receptor stimulating agent · rotigotine · silicone · adult · article · clinical trial · diarrhea · dizziness · drug absorption · drug clearance · drug delivery system · drug distribution · drug elimination · drug formulation · drug metabolism · drug penetration · drug release · drug structure · drug tolerability · fatigue · human · human experiment · isotope labeling · liquid chromatography · liquid scintillation counting · male · mass balance · normal human · phase 1 clinical trial · priority journal · radioactivity · single drug dose · tandem mass spectrometry · Administration, Cutaneous · Adolescent · Adult · Carbon Radioisotopes · Chromatography, Liquid · Dopamine Agonists · Humans · Male · Middle Aged · Tandem Mass Spectrometry · Tetrahydronaphthalenes · Thiophenes
[Abstract]

12 3rd (International) TNO Conference on New Commercial Technical Developments: Interaction of Marketing and Research & Development in the Chemical Industry, Rotterdam, Nederland, 26-27 February 1970
conferenceProceedings 1970    
Keywords: Industry · Commerce · Product development · Chemical industry · Drug industry · Polyisoprene · Detergents
[PDF]

13 Presentatie bij diagnose van insuline afhankelijke Diabetes Mellitus in Nederland
article 1995    
Author: Reeser, H.M. · Hirasing, R.A.
Keywords: Health · Insulin · Child · Diabetes mellitus · Hospitalization · Human · Intravenous drug administration

14 Nieuw ontdekte diabetes mellitus bij kinderen: Wel of niet opnemen?
article 1996    
Author: Hirasing, R.A. · Reeser, H.M. · Goor, J. van · Bruining, G.J.
Keywords: Health · Insulin · Child · Diabetes mellitus · Hospitalization · Human · Intravenous drug administration
[Abstract]

15 PAF-acether-induced release of tissue-type plasminogen activator from vessel walls
article 1985    
Author: Emeis, J.J. · Kluft, C.
Keywords: Biology · 3 amino 1 (3 trifluoromethylphenyl) 2 pyrazoline · 4 bromophenacyl bromide · Acetylsalicylic acid · Diethylcarbamazine · Docebenone · Endetic acid · Indometacin · Mepacrine · Nordihydroguaiaretic acid · Plasminogen activator · Thrombocyte activating factor · Tissue plasminogen activator · Animal experiment · Biological model · Blood and hemopoietic system · Blood clotting · Blood vessel wall · Cardiovascular system · Dose response · Drug accumulation · Drug analysis · Drug blood level · Drug comparison · Drug determination · Drug identification · Drug inhibition · Drug isolation · Drug mechanism · Drug response · Histology · Intravenous drug administration · Nonhuman · Peripheral vascular system · Regional perfusion · Spectrophotometry · Thrombocyte aggregating factor · Animal · Blood Vessels · Calcium · Cyclooxygenase Inhibitors · Fibrinolysis · Lipoxygenase Inhibitors · Male · Phospholipases · Plasminogen Activators · Platelet Activating Factor · Rats · Rats, Inbred Strains · Support, Non-U.S. Gov't
[Abstract]

16 A randomized three-way cross-over study in healthy pituitary-suppressed women to compare the bioavailability of human chorionic gonadotrophin (Pregnyl®) after intramuscular and subcutaneous administration
article 1998    
Author: Mannaerts, B.M.J.L. · Geurts, T.B.P. · Odink, J.
Keywords: Nutrition · Bioequivalence · Human chorionic gonadotrophin · Intramuscular · Pharmacokinetics · Subcutaneous · Chorionic gonadotropin · Adult · Area under the curve · Bioequivalence · Clinical trial · Controlled study · Dose response · Drug absorption · Drug bioavailability · Drug blood level · Drug elimination · Drug half life · Female · Human · Human experiment · Hypopituitarism · Intramuscular drug administration · Normal human · Randomized controlled trial · Subcutaneous drug administration · Administration, Oral · Adolescent · Adult · Chorionic Gonadotropin · Contraceptives, Oral · Cross-Over Studies · Dose-Response Relationship, Drug · Female · Humans · Injections, Intramuscular · Pituitary Gland
[Abstract]

17 Modifying effect of vitamin A on benzo[a]pyrene-induced respiratory tract tumours in hamsters
article 1984    
Author: Beems, R.B.
Keywords: Benzo[a]pyrene · Retinol · Animal experiment · Animal model · Chemical carcinogenesis · Dose response · Drug administration · Drug blood level · Drug efficacy · Drug mechanism · Drug response · Electron microscopy · Epidemiology · Fatality · Mortality · Nonhuman · Oral drug administration · Prevention · Respiratory system · Respiratory tract tumor · Sex difference · Animal · Benzo(a)pyrene · Benzopyrenes · Body Weight · Dose-Response Relationship, Drug · Drug Interactions · Eating · Female · Hamsters · Male · Mesocricetus · Precancerous Conditions · Respiratory Tract Neoplasms · Sex Factors · Support, Non-U.S. Gov't · Vitamin A
[Abstract]

18 Mutagenicity of ethidium bromide after metabolic activation in vitro
article 1976    
Author: Mattern, I.E.
Keywords: Biology · Cell culture · Drug activation · Drug metabolism · Electron microscopy · Ethidium chloride · In vitro study · Mutagenesis · Pharmacokinetics · Theoretical study

19 Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients
article 1998    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Gall, H.E. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Creatinine · Adult · Aged · Area under the curve · Clinical article · Creatinine blood level · Dna adduct · Dna drug complex · Drug blood level · Drug effect · Drug half life · Female · Human · Intravenous drug administration · Kidney function · Male · Malignant neoplastic disease · Priority journal · Amifostine · Antineoplastic Agents · Cisplatin · DNA Adducts · Drug Interactions · Female · Half-Life · Hemofiltration · Humans · Leukocytes · Male · Middle Aged · Neoplasms · Platinum · Radiation-Protective Agents
[Abstract]

20 Bispecific monoclonal antiboldies increase the fibrin-specific fibrinolytic activity of tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA)
article 1992    
Author: Bos, R. · Nieuwenhuizen, W.
Keywords: Health · fibrin · monoclonal antibody · plasminogen activator · tissue plasminogen activator · urokinase · drug carrier · cell fusion · conference paper · drug binding · drug efficacy · drug megadose · endothelium cell · enzyme activity · fibrinolysis · fibrinolytic therapy · hybridoma · plasminogen activation · antibody specificity · drug effect · immunology · metabolism · Antibodies, Monoclonal · Antibody Specificity · Drug Carriers · Fibrin · Fibrinolysis · Human · Kinetics · Plasminogen Activator Inhibitor 1 · Tissue Plasminogen Activator · Urinary Plasminogen Activator

Search results also available in MS Excel format.

Showing 1 to 20 of 930 found. Next | Sort by date