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1 A novel, inducible, citral lyase purified from spores of Penicillium digitatum
article 2002    
Author: Wolken, W.A.M. · Loo, W.J.V. van · Tramper, J. · Werf, M.J. van der
Keywords: Nutrition · Carbon-Carbon Lyases · Chromatography, Gel · Electrophoresis, Polyacrylamide Gel · Enzyme Induction · Enzyme Stability · Hydrogen-Ion Concentration · Monoterpenes · Penicillium · Spores, Fungal · Substrate Specificity · Temperature · Fungi · Penicillium · Penicillium digitatum
[Abstract]

2 Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans
article 1995    
Author: Nijhoff, W.A. · Grubben, M.J.A.L. · Nagengast, F.M. · Jansen, J.B.M.J. · Verhagen, H. · Poppel, G. van · Peters, W.H.M.
Keywords: Biology · Adult · Brassica · Cross-Over Studies · Duodenum · Energy Intake · Enzyme Induction · Female · Glucosinolates · Glutathione · Glutathione Transferase · Human · Intestines · Isoenzymes · Lymphocytes · Male · Metabolic Detoxication, Drug · Rectum · Thiocyanates
[Abstract]

3 Glutathione conjugation as a bioactivation reaction
article 2000    
Author: Bladeren, P.J. van
Keywords: Nutrition · Bioactivation · Glutathione conjugates · Glutathione S-transferases · Cysteine · Glutathione · Glutathione transferase · Lyase · Catalysis · Chemical binding · Chemical reaction · Chromosomal localization · Conjugation · Covalent bond · Detoxification · Enzyme activation · Enzyme activity · Enzyme induction · Enzyme inhibition · Enzyme mechanism · Gene location · Genetic polymorphism · Human · Nonhuman · Protein expression · Reaction analysis · Reduction · Animals · Biotransformation · Carbon-Sulfur Lyases · Enzyme Induction · Glutathione · Glutathione Transferase · Humans · Metabolic Detoxication, Drug · Oxidation-Reduction · Xenobiotics
[Abstract]

4 Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7α-hydroxylase in cultured rat hepatocytes and in vivo in the rat
article 1999    
Author: Post, S.M. · Paul Zoeteweij, J. · Bos, M.H.A. · Wit, E.C.M. de · Havinga, R. · Kuipers, F. · Princen, H.M.G.
Keywords: Biology · Acetates · Animals · Anticholesteremic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Enzyme Induction · Enzyme Inhibitors · Liver · Male · Rats · Rats, Wistar · RNA, Messenger · Sterol O-Acyltransferase · Sulfonic Acids · Triglycerides
[Abstract]

5 Differential sensitivity of human naive and memory CD4+ T cells for dexamethasone
article 1995    
Author: Nijhuis, E.W.P. · Hinloopen, B. · Lier, R.A.W. van · Nagelkerken, L.
Keywords: CD28 · CD45 · Glucocorticoids · Protein kinase C · Antigens, CD2 · Antigens, CD28 · Antigens, CD4 · CD4-Positive T-Lymphocytes · Comparative Study · Dexamethasone · Enzyme Induction · Human · Immunologic Memory · Lymphocyte Activation · Protein Kinase C
[Abstract]

6 Effects of consumption of Brussels sprouts on plasma and urinary glutathione S-transferase class-α and -π in humans
article 1995    
Author: Nijhoff, W.A. · Mulder, T.P.J. · Verhagen, H. · Poppel, G. van · Peters, W.H.M.
Keywords: glucosinolate · glutathione transferase · adult · article · Brassica · controlled study · diet · enzyme blood level · enzyme linked immunosorbent assay · female · human · male · priority journal · sex difference · urine level · vegetable · Adult · Biological Markers · Brassica · Cross-Over Studies · Diet · Enzyme Induction · Female · Glucosinolates · Glutathione Transferase · Human · Isoenzymes · Male · Sex Factors · Vegetables
[Abstract]

7 Selection of Arabidopsis mutants overexpressing genes driven by the promoter of an auxin-inducible glutathione S-transferase gene
article 1999    
Author: Kop, D.A.M. van der · Schuyer, M. · Pinas, J.E. · Zaal, B.J. van der · Hooykaas, P.J.J.
Keywords: Nutrition · Arabidopsis thaliana · Auxin-responsive gene expression · Developmental mutants · Glutathione S-transferase · GST · Gup mutant · Auxin · Beta glucuronidase · Gene expression · Glutathione transferase · Kanamycin · Reporter gene · Transgenic plant · Arabidopsis · Chromosome Mapping · Crosses, Genetic · DNA, Bacterial · Enzyme Induction · Ethyl Methanesulfonate · Gene Expression Regulation, Plant · Genes, Plant · Glutathione Transferase · Indoleacetic Acids · Mutagenesis · Mutagens · Mutation · Phenotype · Plants, Genetically Modified · Promoter Regions (Genetics) · Recombinant Fusion Proteins · Up-Regulation
[Abstract]

8 An expression system based on the promoter region of the Aspergillus awamori 1,4-bèta-endoxylanase A gene
article 1996    
Author: Gouka, R.J. · Hessing, J.G.M. · Punt, P.J. · Stam, H. · Musters, W. · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Enzyme · Glycosidase · Microbial enzyme · Controlled study · Gene expression regulation · Molecular cloning · Nonhuman · Promoter region · Aspergillus · Endo-1,4-beta Xylanases · Enzyme Induction · Gene Expression Regulation, Fungal · Genes, Reporter · Genetic Vectors · Glucan 1,4-alpha-Glucosidase · Glucuronidase · Promoter Regions (Genetics) · RNA, Fungal · RNA, Messenger · Transcription, Genetic · Xylose · Xylosidases · Aspergillus awamori · Aspergillus niger · Trixis
[Abstract]

9 The influence of aging on the metabolism of simultaneously administered hexobarbital enantiomers and antipyrine before and after phenobarbital induction in male rats: A longitudinal study
article 1994    
Author: Groen, K. · Breimer, D.D. · Jansen, E.J. · Bezooijen, C.F.A. van
Keywords: Health · 3 hydroxymethylphenazone · 4 hydroxyphenazone · Norphenazone · Phenazone · Adolescent · Aged · Body weight · Controlled study · Drug blood level · Drug clearance · Drug metabolism · Drug urine level · Enantiomer · Enzyme activity · Enzyme specificity · High performance liquid chromatography · Nonhuman · Survival rate · Aging · Animal · Antipyrine · Cytochrome P-450 Enzyme System · Enzyme Induction · Hexobarbital · Longitudinal Studies · Male · Metabolic Clearance Rate · Phenobarbital · Rats · Rats, Inbred BN · Stereoisomerism
[Abstract]

10 The use of metabolising systems for in vitro testing of endocrine disruptors
article 2008    
Author: Jacobs, M.N. · Janssens, W. · Bernauer, U. · Brandon, E. · Coecke, S. · Combes, R. · Edwards, P. · Freidig, A. · Freyberger, A. · Kolanczyk, R. · Mc Ardie, C. · Mekenyan, O. · Schmieder, P. · Schrader, T. · Takeyoshi, M. · Burg, B. van der
Keywords: Androgenicity · Cytochrome P450 · Endocrine active substances · Endocrine disruption · Estrogenicity · Metabolism · 2,2 bis(1,4 hydroxyphenyl) 1,1,1 trichloroethane · 2,3,7,8 tetrachlorodibenzo para dioxin · Animals · Biotransformation · Cell Proliferation · Endocrine Disruptors · Endocrine System · Enzyme Induction · Humans · Methoxychlor · Skin · Steroids · Transcriptional Activation
[Abstract]

11 Cafestol, the cholesterol-raising factor in boiled coffee, suppresses bile acid synthesis by downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase in rat hepatocytes
article 1997    
Author: Post, S.M. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Animals · Bile Acids and Salts · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Coffee · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Diterpenes · Enzyme Induction · Heat · Hydroxymethylglutaryl CoA Reductases · Hydroxymethylglutaryl-CoA Synthase · Hypercholesterolemia · Liver · Male · Rats · Rats, Wistar · Receptors, LDL · RNA, Messenger · Steroid Hydroxylases · Terpenes · Transcription, Genetic · Triglycerides
[Abstract]

12 Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes
article 1998    
Author: Monshouwer, M. · Klooster, G.A.E. van 't · Nijmeijer, S.M. · Witkamp, R.F. · Miert, A.S.J.P.A.M. van
Keywords: Nutrition · Cytochrome P450 · Hepatocytes · Induction · Pig · Apoprotein · Beta naphthoflavone · Complementary DNA · Cytochrome p450 isoenzyme · Dexamethasone · Ethoxyresorufin deethylase · Ethylmorphine n demethylase · Messenger RNA · Oxygenase · Phenobarbital · Rifampicin · Animal cell · Controlled study · Enzyme activity · Enzyme analysis · Enzyme induction · Liver cell culture · Nonhuman · RNA analysis · RNA hybridization · Swine · Xenobiotic metabolism
[Abstract]

13 Effect of thiabendazole on some rat hepatic xenobiotic metabolising enzymes
article 2004    
Author: Price, R.J. · Scott, M.P. · Walters, D.G. · Stierum, R.H. · Groten, J.P. · Meredith, C. · Lake, B.G.
Keywords: Nutrition · Physiological Sciences · 1-chloro-2,4-dinitrobenzene · BHT · Butylated hydroxytoluene · CDNB · CH · Cumene hydroperoxide · CYP · Cytochrome P450 · DCNB · Enzyme induction · GSH S-transferase · Rat liver · Thiabendazole · Xenobiotic metabolism · apoprotein · butylcresol · cytochrome P450 1A · cytochrome P450 1A1 · cytochrome P450 1A2 · cytochrome P450 2B · cytochrome P450 2B1 · cytochrome P450 2B2 · glutathione transferase · messenger RNA · tiabendazole · animal cell · animal experiment · article · controlled study · dose response · drug megadose · enzyme activation · enzyme activity · enzyme induction · enzyme metabolism · enzyme substrate · liver microsome metabolism · liver mitochondrion · liver weight · male · nonhuman · nucleotide sequence · protein blood level · rat · xenobiotic metabolism · Acyltransferases · Administration, Oral · Animals · Antinematodal Agents · Antioxidants · Butylated Hydroxytoluene · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Glutathione Transferase · Liver · Male · Rats · Rats, Sprague-Dawley · RNA, Messenger · Thiabendazole
[Abstract]

14 Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity
article 2006    
Author: Boerboom, A.M.J.F. · Vermeulen, M. · Woude, H. van der · Bremer, B.I. · Lee-Hilz, Y.Y. · Kampman, E. · Bladeren, P.J. van · Rietjens, I.M.C.M. · Aarts, J.M.M.J.G.
Keywords: Biology · Benzyl isothiocyanate · Fisetin · Glutathione transferase · Kaempferol · Luteolin · Myricetin · Quercetin · Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone) · Taxifolin · Tert butylhydroquinone · Animal cell · Antioxidant activity · Cancer cell culture · Cancer screening · Chemoprophylaxis · Controlled study · Drug potency · Drug structure · Electrophile responsive element mediated gene · Enzyme induction · Gene · Gene activation · Gene expression · Gene induction · Genetic transcription · Human cell · Molecular interaction · Mouse · Nonhuman · Reporter gene · Screening test · Stereospecificity · Structure activity relation · Tandem repeat · Transcription initiation · Validation study · Animals · Base Sequence · Cell Line · DNA Primers · Enzyme Induction · Flavonoids · Gene Expression · Genes, Reporter · Humans · Luciferases · Mice · Plasmids · Structure-Activity Relationship · Transcription, Genetic · Benzyl isothiocyanate · Electrophile-responsive element (EpRE) · Hepa-1c1c7 cells · Stable luciferase reporter cell lines · Transient transfection
[Abstract]

15 Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya
article 2009    
Author: Vermeulen, M. · Boerboom, A.M.M.J.F. · Blankvoort, B.M.G. · Aarts, J.M.M.J.G. · Rietjens, I.M.C.M. · Bladeren, P.J. van · Vaes, W.H.J.
Keywords: Biology · Analytical research · Antioxidant · Electrophile-responsive element · Isothiocyanate · electrophile · glutathione s transferase Ya · glutathione transferase · isothiocyanic acid derivative · luciferase · phenyl isothiocyanate · sulforaphane · unclassified drug · animal cell · article · cell assay · cell line · chemical structure · concentration response · controlled study · drug potency · enzyme induction · gene expression regulation · gene induction · gene location · mouse · nonhuman · reporter gene · Animals · Cell Line · Cell Survival · Gene Expression Regulation · Genes, Reporter · Glutathione Transferase · Isothiocyanates · Luciferases · Mice · Response Elements · Murinae
[Abstract]

16 Natural and recombinant fungal laccases for paper pulp bleaching
article 2004    
Author: Sigoillot, C. · Record, E. · Belle, V. · Robert, J.L. · Levasseur, A. · Punt, P.J. · Hondel, C.A.M.J.J. van den · Fournel, A. · Sigoillot, J.C. · Asther, M.
Keywords: Biology · Biotechnology · fungal enzyme · laccase · recombinant enzyme · fungus · amino terminal sequence · article · Aspergillus niger · Aspergillus oryzae · biotechnology · bleaching · controlled study · delignification · enzyme analysis · enzyme induction · enzyme substrate · Michaelis constant · nonhuman · nucleotide sequence · oxidation reduction reaction · physical chemistry · protein synthesis · pulp processing · Aspergillus niger · Aspergillus oryzae · Biotechnology · Cloning, Molecular · Genes, Fungal · Industrial Microbiology · Laccase · Lignin · Oxidation-Reduction · Paper · Polyporaceae · Recombinant Proteins · Substrate Specificity · Aspergillus · Aspergillus niger · Aspergillus oryzae · Fungi · Pycnoporus cinnabarinus · Triticum aestivum
[Abstract]

17 Increased bioactivation of dihaloalkanes in rat liver due to induction of class Theta glutathione S-transferase T1-1
article 1998    
Author: Sherratt, P.J. · Manson, M.M. · Thomson, A.M. · Hissink, E.A.M. · Neal, G.E. · Bladeren, P.J. van · Green, T. · Hayes, J.D.
Keywords: Nutrition · 3 indolemethanol · Alkane derivative · Antineoplastic agent · Cytochrome p450 · Glutathione transferase · Liver enzyme · Messenger rna · Phenobarbital · Animal tissue · Cancer prevention · Chemoprophylaxis · Controlled study · Cytoplasm · Diet · Enzyme subunit · Female · Immunoblotting · Male · Nonhuman · Priority journal · Rat · Animals · Anticarcinogenic Agents · Biotransformation · Carcinogens · Dietary Supplements · Enzyme Induction · Female · Glutathione Transferase · Humans · Hydrocarbons, Brominated · Isoenzymes · Liver · Male · Methylene Chloride · Phenobarbital · Rats · Rats, Inbred F344 · Sex Characteristics · Xenobiotics · Animalia
[Abstract]

18 Cloning and characterization of the NADPH cytochrome P450 oxidoreductase gene from the filamentous fungus Aspergillus niger
article 1995    
Author: Brink, J.M. van den · Zeijl, C.M.J. van · Brons, J.F. · Hondel, C.A.M.J.J. van den · Gorcom, R.F.M. van
Keywords: Nutrition · Benzoic acid derivative · Reduced nicotinamide adenine dinucleotide phosphate ferrihemoprotein reductase · Amino acid sequence · Aspergillus niger · Gene isolation · Gene sequence · Genetic analysis · Hybridization · Molecular cloning · Nonhuman · Nucleotide sequence · Polymerase chain reaction · Priority journal · Sequence analysis · Structure activity relation · Amidohydrolases · Amino Acid Sequence · Aspergillus niger · Base Sequence · Benzoates · Benzoic Acid · Cloning, Molecular · Conserved Sequence · Enzyme Induction · Gene Dosage · Gene Expression Regulation, Fungal · Genes, Structural, Fungal · Molecular Sequence Data · NADPH-Ferrihemoprotein Reductase · Polymerase Chain Reaction · Restriction Mapping · Sequence Alignment · Sequence Analysis, DNA · Transformation, Genetic
[Abstract]

19 Toxicogenomics of bromobenzene hepatotoxicity: A combined transcriptomics and proteomics approach
article 2003    
Author: Heijne, W.H.M. · Stierum, R.H. · Slijper, M. · Bladeren, P.J. van · Ommen, B. van
Keywords: Toxicology Health · Physiological Sciences · Bromobenzene · cDNA microarray · Hepatotoxicity · Proteomics · Toxicogenomics · Transcriptomics · alpha glutamylcysteine synthetase · bromobenzene · cathepsin L · enzyme · epoxide hydrolase · glutathione · glutathione transferase · heme oxygenase · messenger RNA · peroxiredoxin · proteasome · unclassified drug · animal experiment · animal model · animal tissue · article · controlled study · enzyme activity · enzyme induction · enzyme regulation · enzyme subunit · gene control · gene expression · gene identification · gene induction · genomics · glutathione metabolism · liver toxicity · lysosome · male · nonhuman · nucleotide sequence · oxidative stress · priority journal · protein content · protein degradation · protein depletion · protein expression · protein synthesis · proteomics · rat · RNA analysis · tissue level · unindexed sequence · weight reduction · Animals · Bromobenzenes · Liver · Male · Oligonucleotide Array Sequence Analysis · Pharmacogenetics · Proteomics · Rats · Rats, Wistar · Transcription, Genetic
[Abstract]

20 Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: Implications for the pathogenesis of the hemolytic uremic syndrome
article 1992    
Author: Kar, N.C.A.J. van de · Monnens, L.A.H. · Karmali, M.A. · Hinsbergh, V.W.M. van
Keywords: Health · cell surface receptor · cycloheximide · globotriaosylceramide · interleukin 6 · lipopolysaccharide · lymphotoxin · recombinant interleukin 1 · recombinant interleukin 1alpha · recombinant interleukin 1beta · recombinant tumor necrosis factor alpha · thrombin · verotoxin · article · concentration response · controlled study · cytopathogenic effect · cytotoxicity · endothelium cell · enzyme induction · escherichia coli · hemolytic uremic syndrome · human · human cell · pathogenesis · priority journal · protein synthesis inhibition · receptor binding · thin layer chromatography · Bacterial Toxins · Carbohydrate Conformation · Carbohydrate Sequence · Cell Survival · Cells, Cultured · Cycloheximide · Endothelium, Vascular · Glycolipids · Hemolytic-Uremic Syndrome · Human · Interleukin-1 · Kinetics · Lipopolysaccharides · Molecular Sequence Data · Receptors, Cell Surface · Shiga-Like Toxin I · Support, Non-U.S. Gov't · Time Factors · Trihexosylceramides · Tumor Necrosis Factor · Umbilical Veins
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 24 found. Next | Sort by date