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1 A familial hemorrhagic diathesis in a Dutch family: An inherited deficiency of ??2-antiplasmin
article 1982    
Author: Kluft, C. · Vellenga, E. · Brommer, E.J.P. · Wijngaards, G.
Keywords: Biology · Alpha 2 antiplasmin · Antithrombin · Blood clotting factor 13 · Immunoglobulin a2 · Tranexamic acid · Autosomal recessive inheritance · Bleeding disorder · Blood and hemopoietic system · Diagnosis · Enzyme deficiency · Human cell · Major clinical study · Adolescent · alpha-Macroglobulins · Antiplasmin · Blood Coagulation · Case Report · Child · Child, Preschool · Factor XIII · Fibrinolysis · Hemorrhagic Disorders · Human · Infant · Male · Pedigree · Plasminogen · Support, Non-U.S. Gov't
[Abstract]

2 Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice
article 2003    
Author: Voshol, P.J. · Haemmerle, G. · Ouwens, D.M. · Zimmermann, R. · Zechner, R. · Teusink, B. · Maassen, J.A. · Havekes, L.M. · Romijn, J.A.
Keywords: Health · Glucose · Hormone sensitive lipase · Insulin receptor · Protein kinase B · Triacylglycerol · Triacylglycerol lipase · Unclassified drug · Animal tissue · Controlled study · Enzyme activity · Enzyme deficiency · Enzyme mechanism · Enzyme phosphorylation · Fatty acid blood level · Gluconeogenesis · Glucose transport · Hormone sensitivity · Hyperinsulinemia · Insulin sensitivity · Knockout mouse · Lipid liver level · Lipolysis · Mouse · Nonhuman · Western blotting · Adiponectin · Animals · Blood Glucose · Cholesterol · Cholesterol Esterase · Fasting · Fatty Acids, Nonesterified · Glucose · Insulin · Intercellular Signaling Peptides and Proteins · Liver · Male · Mice · Mice, Knockout · Muscle, Skeletal · Proteins · Receptor, Insulin · Triglycerides
[Abstract]

3 Cost-effectiveness of pharmacogenomics in clinical practice: A case study of thiopurine methyltransferase genotyping in acute lymphoblastic leukemia in Europe
article 2006    
Author: Akker-van Marle, M.E. van den · Gurwitz, D. · Detmar, S.B. · Enzing, C.M. · Hopkins, M.M. · Gutierrez De Mesa, E. · Ibarreta, D.
Keywords: Health · Antineoplastic Agents · Cost-Benefit Analysis · Europe · Genotype · Humans · Leukemia, Lymphocytic, Acute · Methyltransferases · Models, Economic · Pharmacogenetics · 6-mercaptopurine · Acute lymphoblastic leukemia · Adverse drug reactions · Cost-effectiveness analysis · Drug-metabolizing enzymes · Germany · Ireland · Netherlands · Pharmacogenetics · Thiopurine drugs · Thiopurine methyltransferase (TMPT) · United Kingdom · Azathioprine · Drug metabolizing enzyme · Mercaptopurine · Thiopurine methyltransferase · Acute lymphoblastic leukemia · Anorexia · Blood toxicity · Bone marrow suppression · Calculation · Case study · Clinical practice · Cytopenia · Diarrhea · Drug dose regimen · Drug fatality · Drug hypersensitivity · Enteritis · Enzyme activity · Enzyme deficiency · Europe · Graft rejection · Health care quality · Health survey · Heterozygosity · Homozygosity · Hospital cost · Infection · Interview · Leukopenia · Nausea · Pancreatitis · Phenotype · Polymerase chain reaction · Sensitivity and specificity · Sepsis · United Kingdom · Vomiting · Wild type
[Abstract]

4 CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice
article 2003    
Author: Goudriaan, J.R. · Dahlmans, V.E.H. · Teusink, B. · Ouwens, D.M. · Febbraio, M. · Maassen, J.A. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Fatty acid transport · Glucose metabolism · Hepatic steatosis · Hyperinsulinemic clamp · CD36 antigen · fatty acid · glucose · protein kinase B · triacylglycerol · unclassified drug · animal experiment · animal model · animal tissue · controlled study · enzyme activation · enzyme deficiency · fatty acid blood level · glucose blood level · glucose transport · hyperinsulinemia · insulin sensitivity · male · mouse · muscle · nonhuman · spontaneously hypertensive rat · triacylglycerol blood level · Western blotting · wild type · Animals · Antigens, CD36 · Blood Glucose · Body Weight · Eating · Gene Deletion · Insulin · Insulin Resistance · Lipids · Liver · Mice · Mice, Inbred C57BL · Muscle, Skeletal · Rats · Signal Transduction · Triglycerides · Tritium
[PDF] [Abstract]

5 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

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Showing 1 to 5 of 5 found. | Sort by date