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1 Synthesis of pyrophosphonic acid analogues of farnesyl pyrophosphate
article 1995    
Author: Valentijn, A.R.P.M. · Berg, O. van den · Marel, G.A. van der · Cohen, L.H. · Boom, J.H. van
Keywords: Health · Enzyme inhibitor · Phosphonic acid derivative · Squalene synthase inhibitor · Drug synthesis · Reaction analysis
[Abstract]

2 Inhibitors of protein:farnesyl transferase and protein:geranylgeranyl transferase I : Synthesis of homologous diphosphonate analogs of isoprenylated pyrophosphate
article 1998    
Author: Overhand, M. · Stuivenberg, H.R. · Pieterman, E. · Cohen, L.H. · Leeuwen, R.E.W. van · Valentijn, A.R.P.M. · Overkleeft, H.S. · Marel, G.A. van der · Boom, J.H. van
Keywords: Health · bisphosphonic acid derivative · enzyme inhibitor · geranyltransferase · protein farnesyltransferase · article · enzyme activity · enzyme inhibition · enzyme specificity · phosphate metabolism · priority journal
[Abstract]

3 The effect of storage of whole potatoes of three cultivars on the patatin and protease inhibitor content; a study using capillary electrophoresis and MALDI-TOF mass spectrometry
article 1999    
Author: Pots, A.M. · Gruppen, H. · Diepenbeek, R. van · Lee, J.J. van der · Boekel, M.A.J.S. van · Wijngaards, G. · Voragen, A.G.J.
Keywords: Capillary electrophoresis · MALDI-TOF · Potato protein · Storage · buffer · capillary electrophoresis · cultivar · determination of content · dormancy · enzyme activity · enzyme assay · enzyme degradation · enzyme inhibitor · enzyme stability · mass spectrometry · matrix assisted laser desorption ionization time of flight mass spectrometry · molecular size · patatin · physiology · postharvest period · potato · proteinase
[Abstract]

4 The bispyridinium-dioxime HLö-7. A potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman
article 1989    
Author: Jong, L.P.A.de · Verhagen, M.A.A. · Langenberg, J.P. · Hagedorn, I. · Löffler, M.
Keywords: Biology · Bis(pyridinium oxime) derivative · Enzyme inhibitor · Organophosphorus compound · Radioisotope · Enzyme reactivation · Fish · Human · Nonbiological model · Nonhuman · Normal human · Rat · Stereoisomerism · Acetylcholinesterase 9000-81-1 · Animal · Cholinesterase Reactivators · Eels · Human · In Vitro · Organophosphorus Compounds · Oximes · Phosphoric Acid Esters · Pyridines · Pyridinium Compounds · Stereoisomerism · Structure-Activity Relationship · Organophosphorus compounds · Oximes · Phosphoric acid esters · Pyridines · Pyridinium compounds · Soman, 96-64-0 · Tabun, 77-81-6
[Abstract]

5 Kinetic characteristics of acidic and alkaline ceramidase in human epidermis
article 2007    
Author: Houben, E. · Uchida, Y. · Nieuwenhuizen, W.F. · Paepe, K. de · Vanhaecke, T. · Holleran, W.M. · Rogiers, V.
Keywords: Nutrition · Food technology · Ceramidase · Epidermis · Kinetic parameters · acylsphingosine deacylase · enzyme inhibitor · ethanolamine derivative · isoenzyme · adult · article · enzyme activity · enzyme analysis · enzyme assay · enzyme inhibition · enzyme kinetics · enzyme substrate · enzymology · epidermis · female · human · human tissue · isoenzyme analysis · isotope labeling · normal human · nucleotide sequence · priority journal · zymography · Adult · Amidohydrolases · Enzyme Repression · Epidermis · Female · Humans · Hydrogen-Ion Concentration · Isoenzymes · Kinetics · Middle Aged · Skin Absorption
[Abstract]

6 Role of the glycosaminoglycan component of thrombomodulin in its acceleration of the inactivation of single-chain urokinase-type plasminogen activator by thrombin
article 1993    
Author: Munk, G.A.W. de · Parkinson, J.F. · Groeneveld, E. · Bang, N.U. · Rijken, D.C.
Keywords: chondroitin 4 sulfate · chondroitin abc lyase · glycosaminoglycan · mutant protein · thrombomodulin · urokinase · dissociation constant · enzyme inactivation · enzyme inhibitor interaction · Chondroitin Lyases · Dose-Response Relationship, Drug · Glycosaminoglycans · Glycosylation · Human · Receptors, Cell Surface · Receptors, Thrombin · Recombinant Proteins · Structure-Activity Relationship · Support, Non-U.S. Gov't · Thrombin · Urinary Plasminogen Activator
[Abstract]

7 Chemically modified tetracyclines stimulate matrix metalloproteinase-s production by periodontal ligament cells
article 2006    
Author: Bildt, M.M. · Snoek-van Beurden, A.M.P. · Groot, J. de · El, B. van · Kuijpers-Jagtman, A.M. · Hoff, J.W. van den
Keywords: Biology · Biomedical Research · Chemically modified tetracyclines · Gelatin zymography · Matrix metalloproteinases · Periodontal ligament · DNA · Enzyme inhibitor · Gelatin · Gelatinase A · Gelatinase B · Recombinant protein · Tetracycline derivative · Analysis of variance · Iosynthesis · Cell culture · Chemistry · Drug antagonism · Drug effect · Human · Metabolism · Nonparametric test · Periodontal ligament · Polyacrylamide gel electrophoresis · Western blotting · Analysis of Variance · Blotting, Western · Cells, Cultured · DNA · Electrophoresis, Polyacrylamide Gel · Enzyme Inhibitors · Gelatin · Humans · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Periodontal Ligament · Recombinant Proteins · Statistics, Nonparametric · Tetracyclines
[Abstract]

8 Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm doxycycline selectively depletes aortic wall neutrophils and cytotoxic t cells
article 2009    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Bockel, J.H. van · Wolterbeek, R. · Kleemann, R.
Keywords: Health · Aneurysm · Immunology · Inflammation · Molecular biology · Trials · Doxycycline · Gelatinase B · Granulocyte colony stimulating factor receptor · Interleukin 13 · Interleukin 6 · Interleukin 8 · Antiinfective agent · CCAAT enhancer binding protein · Enzyme inhibitor · IL6 protein, human · Transcription factor AP 1 · Transcription factor RelA · Abdominal aorta aneurysm · Aged · Cytotoxic T lymphocyte · Drug effect · Drug megadose · Drug tolerability · Enzyme inhibition · Aortic Aneurysm, Abdominal · CCAAT-Enhancer-Binding Proteins · Doxycycline · Enzyme Inhibitors · Matrix Metalloproteinase 9 · Middle Aged · Neutrophils · T-Lymphocytes, Cytotoxic · Vasculitis
[PDF] [Abstract]

9 Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10
article 1996    
Author: Kappers, W.A. · Groene, E.M. de · Kleij, L.A. · Witkamp, R.F. · Zweers-Zeilmaker, W.M. · Feron, V.J. · Horbach, G.J.
Keywords: Toxicology · CYP2C9 protein, human · cytochrome P450 · diclofenac · enzyme inhibitor · flurbiprofen · ketoprofen · mixed function oxidase · nonsteroid antiinflammatory agent · phenylbutazone · sulfaphenazole · tolbutamide · tolbutamide 4 hydroxylase · tolbutamide 4-hydroxylase · unspecific monooxygenase · animal · article · cell line · Cricetulus · drug interaction · gene expression · genetic transfection · genetics · hamster · human · hydroxylation · lung · metabolism · methylation · Animals · Anti-Inflammatory Agents, Non-Steroidal · Aryl Hydrocarbon Hydroxylases · Cell Line · Cricetinae · Cricetulus · Cytochrome P-450 Enzyme System · Diclofenac · Drug Interactions · Enzyme Inhibitors · Flurbiprofen · Gene Expression · Humans · Hydroxylation · Ketoprofen · Lung · Methylation · Mixed Function Oxygenases · Phenylbutazone · Sulfaphenazole · Tolbutamide · Transfection
[Abstract]

10 Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice
article 2006    
Author: Korsheninnikova, E. · Zon, G.C.M. van der · Voshol, P.J. · Janssen, G.M. · Havekes, L.M. · Grefhorst, A. · Kuipers, F. · Reijngoud, D.-J. · Romijn, J.A. · Ouwens, D.M. · Maassen, J.A.
Keywords: Biology · Biomedical Research · Hepatic steatosis · High-fat feeding · Nutrient sensing · Enzyme inhibitor · Glucose · Hydroxymethylglutaryl coenzyme A reductase kinase · Mammalian target of rapamycin · Protein kinase B · Protein S6 · S6 kinase · Tetradecylglycidic acid · Unclassified drug · Animal experiment · Animal model · Animal tissue · Controlled study · Diabetic obesity · Diabetogenesis · Enzyme activation · Glucose clamp technique · Hyperinsulinemia · Insulin resistance · Lipid diet · Liver homogenate · Liver mitochondrion · Mitochondrial membrane · Nonhuman · Nutrient concentration · Nutrient content · Protein blood level · Protein induction · Protein phosphorylation · Protein synthesis · Protein targeting · Species comparison · 1-Phosphatidylinositol 3-Kinase · Animals · Blood Glucose · Dietary Fats · DNA, Mitochondrial · Electron Transport Complex IV · Fatty Acids · Fatty Liver · Insulin · Insulin Resistance · Leucine · Liver · Male · Mice · Mice, Inbred C57BL · Phosphorylation · Protein Kinases · Ribosomal Proteins
[Abstract]

11 Calcium measurements in living filamentous fungi expressing codon-optimized aequorin
article 2004    
Author: Nelson, G. · Kozlova-Zwinderman, O. · Collis, A.J. · Knight, M.R. · Fincham, J.R.S. · Stanger, C.P. · Renwick, A. · Hessing, J.G.M. · Punt, P.J. · Hondel, C.A.M.J.J. van den · Read, N.D.
Keywords: Biology · Biotechnology · Aequorin · Calcimycin · Calcium · Calcium channel · Calcium channel blocking agent · Calcium channel stimulating agent · Cation · Chelating agent · Cyclopiazonic acid · Ethylene glycol 1,2 bis(2 aminophenyl) ether n,n,n',n' tetraacetic acid · Recombinant protein · 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid · Drug derivative · Egtazic acid · Enzyme inhibitor · Indole derivative · Ionophore · Aspergillus awamori · Aspergillus niger · Codon · Concentration (parameters) · Controlled study · Fungus · Measurement · Neurospora crassa · Nonhuman · Osmotic stress · Physical chemistry · Priority journal · Protein expression · Signal transduction · Stimulus · Stimulus response · Aspergillus · Calcium signaling · Cytology · Genetics · Mechanical stress · Metabolism · Molecular genetics · Nucleotide sequence · Osmotic pressure · Physiology · Sequence alignment · Aspergillus · Aspergillus awamori · Aspergillus niger · Fungi · Neurospora · Neurospora crassa · Aequorin · Aspergillus · Base Sequence · Calcimycin · Calcium · Calcium Channel Blockers · Calcium Signaling · Chelating Agents · Codon · Egtazic Acid · Enzyme Inhibitors · Indoles · Ionophores · Molecular Sequence Data · Neurospora crassa · Osmotic Pressure · Recombinant Proteins · Sequence Alignment · Stress, Mechanical
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 11 of 11 found. | Sort by date