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Showing 1 to 11 of 11 found. | Sort by date

1 The interaction of recombinant tissue type plasminogen activator and recombinant plasminogen activator (r-PA/BM 06.022) with human endothelial cells
article 1997    
Author: Mulder, M. · Kohnert, U. · Fischer, S. · Hinsbergh, V.W.M. van · Verheijen, J.H.
Keywords: Binding Sites · Catalysis · Cells, Cultured · Endothelium, Vascular · Fibrinolytic Agents · Humans · Plasminogen Activators · Protein Binding · Recombinant Proteins · Tissue Plasminogen Activator
[Abstract]

2 Unfractionated and low molecular weight heparin affect fibrin structure and angiogenesis in Vitro
article 2000    
Author: Collen, A. · Smorenburg, S.M. · Peters, E. · Lupu, F. · Koolwijk, P. · Noorden, C. van · Hinsbergh, V.W.M. van
Keywords: Cell Division · Dose-Response Relationship, Drug · Endothelium, Vascular · Fibrin · Fibrinolytic Agents · Heparin · Heparin, Low-Molecular-Weight · Humans · Neovascularization, Physiologic
[Abstract]

3 Tumor necrosis factor induces the production of urokinase-type plasminogen activator by human endothelial cells
article 1990    
Author: Hinsbergh, V.W.M. van · Berg, E.A. van den · Fiers, W. · Dooijewaard, G.
Keywords: Biological Factors · Cells, Cultured · Cytokines · Endothelium, Vascular · Fibrinolytic Agents · Gene Expression Regulation · Human · Plasmin · Plasminogen Activators · Plasminogen Inactivators · RNA, Messenger · Tumor Necrosis Factor · Urinary Plasminogen Activator
[Abstract]

4 Interaction of reteplase with heparin. A comparison between reteplase and alteplase
article 1996    
Author: Rijken, D.C. · Jie, A.F.H.
Keywords: Biology · Alteplase · BM 06.022 · Fibrinolysis · Heparin · Plasminogen activation · Reteplase · Thrombolysis · Tissue-type plasminogen activator · alteplase · heparin · reteplase · article · blood clot lysis · controlled study · drug interaction · fibrinolysis · plasminogen activation · priority journal · Amidohydrolases · Anticoagulants · Drug Synergism · Enzyme Activation · Fibrinolytic Agents · Glycosylation · Heparin · Humans · Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase · Plasminogen · Plasminogen Activators · Protein Binding · Recombinant Proteins · Sepharose · Tissue Plasminogen Activator
[Abstract]

5 In vitro stabililty of a tissue-type plasminogen activator mutant, BM 06.022, in human plasma
article 1994    
Author: Rijken, D.C. · Groeneveld, E. · Barrett-Bergshoeff, M.M.
Keywords: Biology · alpha 1 antitrypsin · alpha 2 antiplasmin · alteplase · fibrinogen · plasmin · reteplase · tissue plasminogen activator · fibrinolytic agent · proteinase inhibitor · recombinant protein · dose response · drug activity · drug half life · drug inactivation · drug stability · immunoblotting · plasma · polyacrylamide gel electrophoresis · blood · genetics · half life time · mutation · Drug Stability · Fibrinolytic Agents · Half-Life · Human · Mutation · Protease Inhibitors · Recombinant Proteins · Tissue Plasminogen Activator
[Abstract]

6 Interactions between staphylokinase, plasmin(ogen), and fibrin. Staphylokinase discriminates between free plasminogen and plasminogen bound to partially degraded fibrin
article 1996    
Author: Sakharov, D.V. · Lijnen, H.R. · Rijken, D.C.
Keywords: Biology · Fluorescein isothiocyanate · Staphylokinase · Blood clot lysis · Fluorescence microscopy · Molecular weight · Plasma · Protein protein interaction · Chromatography, Gel · Fibrin · Fibrinolysis · Fibrinolytic Agents · Fluorescein-5-isothiocyanate · Fluorescence Polarization · Humans · Kinetics · Metalloendopeptidases · Microscopy, Confocal · Plasmin · Plasminogen · Protein Binding · Recombinant Proteins · Substrate Specificity · Bacteria (microorganisms)
[PDF] [Abstract]

7 Composition and susceptibility to thrombolysis of human arterial thrombi and the influence of their age
article 1992    
Author: Brommer, E.J.P. · Bockel, J.H. van
Keywords: Alteplase · Anistreplase · Fibrinolytic agent · Plasminogen · Saruplase · Streptokinase · Tissue plasminogen activator · Urokinase · Aging · Artery thrombosis · Blood clot lysis · Human · Anistreplase · Comparative Study · Dose-Response Relationship, Drug · Fibrin · Fibrin Fibrinogen Degradation Products · Fibrinolytic Agents · Human · Osmolar Concentration · Plasma · Plasminogen · Recombinant Proteins · Sodium Chloride · Streptokinase · Thrombosis · Time Factors · Tissue Plasminogen Activator · Urinary Plasminogen Activator
[Abstract]

8 An enhancing effect of poly-lysine on the activation plasminogen
article 1982    
Author: Allen, R.A.
Keywords: chondroitin sulfate · plasminogen · plasminogen activator · polyarginine · polylysine · polyornithine · protamine sulfate · tripeptide · urokinase · blood clotting · in vitro study · Binding Sites · Female · Fibrinolytic Agents · Human · Melanoma · Molecular Weight · Peptides · Plasminogen Activators · Polylysine · Sodium Chloride · Support, Non-U.S. Gov't · Urinary Plasminogen Activator · Uterus
[Abstract]

9 Quantitative analysis of Tenecteplase in rat plasma samples using LC-MS/MS as an alternative for ELISA
article 2007    
Author: Buscher, B.A.P. · Gerritsen, H. · Schöll, I. van · Cnubben, N.H.P. · Brüll, L.P.
Keywords: Biology · Analytical research · Digestion · Liquid chromatography · Mass spectrometry · Plasma · Proteins · Quantitative analysis · Blood · Digestive system · Drug products · Enzymes · Sensitivity analysis · Internal standard · Tenecteplase · Trypsin · Chemical analysis · tenecteplase · animal experiment · article · blood sampling · controlled study · drug distribution · enzyme linked immunosorbent assay · liquid chromatography · mass spectrometry · nonhuman · priority journal · quantitative analysis · rat · single drug dose · Animals · Chromatography, Liquid · Enzyme-Linked Immunosorbent Assay · Fibrinolytic Agents · Rats · Sensitivity and Specificity · Tandem Mass Spectrometry · Tissue Plasminogen Activator · Rattus
[Abstract]

10 Disagreement between bedside and laboratory activated partial thromboplastin time and international normalized ratio for various novel anticoagulants
article 2001    
Author: Kemme, M.J.B. · Faaij, R.A. · Schoemaker, R.C. · Kluft, C. · Meijer, P. · Cohen, A.F. · Burggraaf, J.
Keywords: Activated partial thromboplastin time · Bedside monitor · International normalized ratio · Prothrombin time · Anticoagulant agent · Fondaparinux · Napsagatran · Recombinant tissue factor pathway inhibitor · Adult · Blood clotting parameters · Blood sampling · Clinical article · Intermethod comparison · Laboratory test · Outpatient care · Partial thromboplastin time · Prothrombin time · Thromboembolism · Anticoagulants · Antithrombins · Drug Monitoring · False Negative Reactions · False Positive Reactions · Fibrinolytic Agents · Heparin · Humans · Laboratories · Naphthalenes · Oligosaccharides · Partial Thromboplastin Time · Piperidines · Point-of-Care Systems · Reproducibility of Results · Warfarin
[Abstract]

11 Inhibition of mannose receptor-mediated-clearance of tissue-type plasminogen activator (t-PA) by dextran : A new explanation for its antithrombotic effect
article 1997    
Author: Noorman, F. · Barrett-Bergshoeff, M.M. · Bekkers, M. · Emeis, J.J. · Rijken, D.C.
Keywords: Biology · Anticoagulant agent · Dextran · Dextran 40 · Dextran 70 · Low density lipoprotein receptor · Mannose receptor · Tissue plasminogen activator · Animal experiment · Bolus injection · Controlled study · Deep vein thrombosis · Drug infusion · Drug mechanism · Human · Human cell · Macrophage · Male · Monocyte · Nonhuman · Plasma clearance · Priority journal · Protein blood level · Rat · Thrombogenesis · Acetylgalactosamine · Animals · Cells, Cultured · Depression, Chemical · Dextrans · Fibrinolytic Agents · Glucose · Humans · Lectins, C-Type · Macrophages · Male · Mannose · Mannose-Binding Lectins · Metabolic Clearance Rate · Protein Binding · Rats · Rats, Wistar · Receptors, Cell Surface · Receptors, LDL · Recombinant Proteins · Tissue Plasminogen Activator
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 11 of 11 found. | Sort by date