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1 Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy
article 2018    
Author: Stee, M.F. van · Graaf, A.A. de · Groen, A.K.
Keywords: Biology · Atorvastatin · Combination therapy · Dyslipidemia · Glucose metabolism · Lipid metabolism · Metformin · Simvastatin · Type 2 diabetes
[PDF] [Abstract]

2 Hepatic Steatosis: A Mediator of the Metabolic Syndrome. Lessons from Animal Models
article 2004    
Author: Boer, M. den · Voshol, P.J. · Kuipers, F. · Havekes, L.M. · Romijn, J.A.
Keywords: Biology · Biomedical Research · Fatty acid metabolism · Glucose metabolism · Insulin resistance · Lipoprotein metabolism · Mouse models · Alcohol · Triacylglycerol · Animal experiment · Animal model · Disease association · Dyslipidemia · Endocrine system · Genetic transcription · Glucose metabolism · Lnsulin resistance · Lipid liver level · Metabolic syndrome X · Mouse · Non insulin dependent diabetes mellitus · Nonhuman · Partition coefficient · Pathophysiology · Rodent · Short survey · Adipose Tissue · Animals · Diabetes Mellitus, Type 2 · Dogs · Fatty Acids · Fatty Liver · Glucose · Homeostasis · Humans · Hyperlipidemias · Insulin Resistance · Liver · Metabolic Syndrome X · Mice · Models, Animal · Models, Biological · Obesity · Rats · Rats, Zucker · Transcription, Genetic · Triglycerides
[Abstract]

3 Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice
article 2006    
Author: Heijboer, A.C. · Hoek, A.M. van den · Parlevliet, E.T. · Havekes, L.M. · Romijn, J.A. · Pijl, H. · Corssmit, E.P.M.
Keywords: Biology · Biomedical Research · Animal models · GHRP-6 · Glucose metabolism · Gut hormone · Hyperinsulinaemic- euglycaemic clamp technique · Insulin resistance · Tracer methodology · Deoxyglucose · Desoctanoylghrelin · Ghrelin · Growth hormone secretagogue receptor · Growth hormone secretagogue receptor stimulating agent · Histidyl dextro tryptophylalanyltryptophyl dextro phenylalanyllysinamide · Peptide derivative · Unclassified drug · Adipose tissue · Adolescent · Body weight · Controlled study · Food intake · Glucogenesis · Glucose clamp technique · Glucose metabolism · Hormone action · Hyperinsulinemia · Insulin sensitivity · Isotope dilution assay · Liver metabolism · Mouse · Muscle metabolism · Nonhuman · Animals · Body Weight · Glucose · Hepatocytes · Insulin · Male · Mice · Mice, Inbred C57BL · Peptide Hormones
[Abstract]

4 Moderate Alcohol Consumption and Insulin Sensitivity: Observations and Possible Mechanisms
article 2007    
Author: Hendriks, H.F.J.
Keywords: Biomedical Research · Adiponectin · Alcohol Drinking · Diabetes Mellitus · Epidemiology · Human · Insulin · Mechanism · Nutrition Intervention · fatty acid · glucose · insulin · adipose tissue · alcohol consumption · article · cardiovascular disease · cardiovascular risk · endocrine function · fatty acid metabolism · glucose metabolism · human · insulin sensitivity · modulation · non insulin dependent diabetes mellitus · priority journal
[Abstract]

5 Kinetics of mRNA and protein synthesis of genes controlled by the 1,4- β-endoxylanase A promoter in controlled fermentations of Aspergillus awamori
article 1996    
Author: Gouka, R.J. · Stam, H. · Fellinger, A.J. · Muijsenberg, R.J.G.T. · Wijngaard, A.J. van de · Punt, P.J. · Musters, W. · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Triacylglycerol lipase · Cell culture · Enzyme activity · Enzyme analysis · Gene expression · Gene expression regulation · Glucose metabolism · Promoter region · Protein synthesis · Rna analysis · Aspergillus · Endo-1,4-beta Xylanases · Fermentation · Gene Expression Regulation, Fungal · Glucose · Glucuronidase · Kinetics · Lipase · Promoter Regions (Genetics) · Protein Biosynthesis · Recombinant Fusion Proteins · RNA, Messenger · Xylose · Xylosidases · Aspergillus awamori · Escherichia coli · Thermomyces lanuginosus
[Abstract]

6 Quantifying phenotypic flexibility as the response to a high-fat challenge test in different states of metabolic health
article 2015    
Author: Kardinaal, A.F.M. · Erk, M.J. van · Dutman, A.E. · Stroeve, J.H.M. · Steeg, E. van de · Bijlsma, S. · Kooistra, T. · Ommen, B. van · Wopereis, S.
Keywords: Biology · Clinical study · Eicosanoids · Human physiology · Nutrition · Systems biology · Fat · Glucose · Adipose tissue · Adult · Aged · Controlled study · Glucose metabolism · Health · Homeostasis · Human · Male · Metabolic syndrome X · Metabolism · Open study · Pilot study · Provocation test · Quantitative analysis · Stress · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

7 A pilot study to investigate effects of inulin on Caco-2 cells through in vitro metabolic fingerprinting
article 2003    
Author: Lamers, R.-J.A.N. · Wessels, E.C.H.H. · Sandt, J.J.M. van de · Venema, K. · Schaafsma, G. · Greef, J. van der · Nesselrooij, J.H.J. van
Keywords: Nutrition Packaging · Analytical research · 1H NMR spectroscopy · Metabolic fingerprinting · Biochemical marker · Cell culture · Cell metabolism · Cell strain CACO 2 · Chemical analysis · Controlled study · Experimental model · Glucose metabolism · Health status · Human cell · In vitro study · In vivo study · Laboratory test · Multivariate analysis · Nutrition · Pilot study · Proton nuclear magnetic resonance · Alanine · Analysis of Variance · Caco-2 Cells · Colon · Fermentation · Glucose · Glutamic Acid · Humans · Inulin · Ketoglutaric Acids · Lactic Acid · Magnetic Resonance Spectroscopy · Niacin · Niacinamide · Proline · Succinic Acid
[Abstract]

8 Sixteen hours of fasting differentially affects hepatic and muscle insulin sensitivity in mice
article 2005    
Author: Heijboer, A.C. · Donga, E. · Voshol, P.J. · Dang, Z.C. · Havekes, L.M. · Romijn, J.A. · Corssmit, E.P.M.
Keywords: Biology · Biomedical Research · Glucose metabolism · Insulin action · Isotopes · Steatosis · Transcription factors · Glucose · Messenger RNA · Animal experiment · Animal tissue · Controlled study · Diet restriction · Fatty acid oxidation · Gene expression · Gluconeogenesis · Glucose transport · Glycogenolysis · Insulin sensitivity · Lipogenesis · Mouse · Mouse strain · Nonhuman · Skeletal muscle · Wild type · Biosynthesis · C57BL mouse · Drug effect · Genetics · Glucose blood level · Metabolism · Physiology · Time · Animals · Blood Glucose · Body Weight · Fasting · Insulin · Insulin Resistance · Liver · Male · Mice · Mice, Inbred C57BL · Muscle, Skeletal · RNA, Messenger · Time Factors · Triglycerides
[PDF] [Abstract]

9 Endothelial function and baroreflex sensitivity according to the oral glucose tolerance test in patients with coronary artery disease and normal fasting glucose levels
article 2005    
Author: Wykretowicz, A. · Guzik, P. · Bartkowiak, G. · Krauze, T. · Kasinowski, R. · Dziarmaga, M. · Wesseling, K.H. · Wysocki, H.
Keywords: Augmentation index · Baroreflex sensitivity · Coronary artery disease · Diabetes · Endothelial function · Glucose tolerance · salbutamol · age · clinical article · controlled study · coronary artery disease · coronary hemodynamics · diabetes mellitus · endothelium · glucose blood level · glucose metabolism · heart infarction · impaired glucose tolerance · oral glucose tolerance test · pressoreceptor reflex · priority journal · scoring system · transluminal coronary angioplasty · Adult · Aged · Aging · Albuterol · Angioplasty, Transluminal, Percutaneous Coronary · Baroreflex · Blood Glucose · Coronary Arteriosclerosis · Diabetes Mellitus · Endothelium, Vascular · Fasting · Female · Glucose Tolerance Test · Hemodynamic Processes · Humans · Male · Middle Aged · Severity of Illness Index · Vasodilator Agents
[Abstract]

10 Multivariate analysis of microarray data by principal component discriminant analysis: Prioritizing relevant transcripts linked to the degradation of different carbohydrates in Pseudomonas putida S12
article 2006    
Author: Werf, M.J. van der · Pieterse, B. · Luijk, N. van · Schuren, F. · Werff van der - Vat, B. van der · Overkamp, K. · Jellema, R.H.
Keywords: Biology · Biotechnology · bacterial RNA · cytochrome · fructose · gluconic acid · glucose · glucose dehydrogenase · iron · quinone derivative · succinic acid · article · bacterial gene · bacterium culture · carbohydrate metabolism · carbon source · cluster analysis · controlled study · discriminant analysis · down regulation · fermentation medium · fructose metabolism · gene identification · genetic transcription · glucose metabolism · intermethod comparison · metabolic regulation · microarray analysis · molecular cloning · multivariate analysis · nonhuman · plots and curves · principal component analysis · priority journal · Pseudomonas putida · regulatory mechanism · respiratory chain · RNA analysis · RNA isolation · transcriptomics · upregulation · Carbohydrate Metabolism · Culture Media · Genes, Bacterial · Multivariate Analysis · Oligonucleotide Array Sequence Analysis · Pseudomonas putida · Bacteria (microorganisms) · Pseudomonas putida
[Abstract]

11 Response of apolipoprotein E*3-Leiden transgenic mice to dietary fatty acids: Combining liver proteomics with physiological data
article 2005    
Author: Roos, B. de · Duivenvoorden, I. · Rucklidge, G. · Reid, M. · Ross, K. · Lamers, R.J.A.N. · Voshol, P.J. · Havekes, L.M. · Teusink, B.
Keywords: Biology · Biomedical Research · Conjugated linoleic acid · Elaidic acid · Fenofibrate · Glucose · Liver protein · Membrane protein · Animal model · Atherosclerosis · Controlled study · Diet · Diet therapy · Fat intake · Fatty acid oxidation · Glucose metabolism · Insulin resistance · Ischemic heart disease · Lipoprotein metabolism · Metabolic syndrome X · Mouse · Nonhuman · Principal component analysis · Structural proteomics · Transgenic mouse · 3-Hydroxybutyric Acid · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Blood Glucose · Cell Membrane · Cholesterol · Cytosol · Dietary Fats · Disease Models, Animal · Electrophoresis, Gel, Two-Dimensional · Fatty Acids · Female · Fish Oils · Insulin · Linoleic Acids, Conjugated · Lipid Metabolism · Lipids · Liver · Mice · Mice, Transgenic · Oleic Acid · Organ Size · Proteins · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Triglycerides · Animalia · Mus musculus

12 Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation
article 2008    
Author: Hoek, A.M. van den · Heijningen, C. van · Schröder - Elst, J.P. van der · Ouwens, D.M. · Havekes, L.M. · Romijn, J.A. · Kalsbeek, A. · Pijl, H.
Keywords: corticosterone · glucose · insulin · liothyronine · neuropeptide Y · testosterone · thyroxine · antidiabetic agent · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · glucose metabolism · hormone blood level · insulin resistance · liver · male · nonhuman · parasympathetic innervation · priority journal · rat · sympathetic innervation · adrenergic system · animal · drug effect · glucose blood level · glucose clamp technique · hyperinsulinism · innervation · intracerebroventricular drug administration · metabolism · pathophysiology · physiology · sympathectomy · vagotomy · Wistar rat · Animals · Blood Glucose · Glucose Clamp Technique · Hyperinsulinism · Hypoglycemic Agents · Injections, Intraventricular · Insulin · Insulin Resistance · Liver · Male · Neuropeptide Y · Parasympathectomy · Rats · Rats, Wistar · Sympathectomy · Sympathetic Nervous System
[Abstract]

13 Leptin deficiency per se dictates body composition and insulin action in ob/ob mice
article 2008    
Author: Hoek, A.M. van den · Teusink, B. · Voshol, P.J. · Havekes, L.M. · Romijn, J.A. · Pijl, H.
Keywords: Biology · Adiposity hormone · Brain · Insulin resistance · Metabolism · Type 2 diabetes mellitus · glucose · insulin · leptin · animal experiment · animal tissue · article · body composition · body weight · caloric restriction · controlled study · diet restriction · female · gluconeogenesis · glucose clamp technique · glucose metabolism · hormone deficiency · insulin resistance · insulin sensitivity · lean body weight · leptin deficiency · male · mouse · mouse strain · nonhuman · obesity · pathophysiology · priority journal · quantitative analysis · signal transduction · wild type · Animals · Blood Glucose · Body Composition · Body Weight · Fatty Acids, Nonesterified · Female · Food Deprivation · Glucose · Glucose Clamp Technique · Growth and Development · Insulin · Leptin · Male · Mice · Mice, Inbred C57BL · Mice, Obese · Mice, Transgenic · Obesity
[Abstract]

14 Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1
article 2001    
Author: Koopmans, S.J. · Jong, M.C. · Que, I. · Dahlmans, V.E.H. · Pijl, H. · Radder, J.K. · Frölich, M. · Havekes, L.M.
Keywords: Biology · APOC1 · Hypertension · Insulin resistance · Insulin resistance syndrome · Lipoprotein · NEFA · Fatty acid · Palmitic acid · Triacylglycerol · Tritium · Very low density lipoprotein · Adipose tissue · Animal model · Animal tissue · Blood pressure · Cholesterol blood level · Clearance · Controlled study · Fatty acid metabolism · Gene overexpression · Glucose blood level · Glucose clamp technique · Glucose metabolism · Glycogen synthesis · Glycolysis · Heart rate · Hyperinsulinemia · Hyperlipidemia · Hypertension · In vivo study · Infusion · Insulin resistance · Lipid transport · Lipogenesis · Mean arterial pressure · Mouse · Nonhuman · Skeletal muscle · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Blood Pressure · Cholesterol · Fatty Acids, Nonesterified · Gene Expression · Glucose · Glucose Clamp Technique · Glycogen · Humans · Hyperlipidemias · Insulin · Lipid Metabolism · Liver · Mice · Mice, Transgenic · Muscle, Skeletal · Palmitic Acid · Triglycerides · Tritium
[Abstract]

15 Hypercholesterolemia reduces collateral artery growth more dominantly than hyperglycemia or insulin resistance in mice
article 2006    
Author: Weel, V. van · Vries, M. de · Voshol, P.J. · Verloop, R.E. · Eilers, P.H.C. · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Arteriogenesis · Cholesterol · Collateral circulation · Diabetes · NOD mice · Peripheral vascular disease · Glucose · Streptozocin · Triacylglycerol · Lipid · Angiogenesis · Angiography · Animal model · Artery occlusion · Cholesterol blood level · Controlled study · Diabetes mellitus · Diet · Fatty acid blood level · Femoral artery · Glucose blood level · Glucose metabolism · Hypercholesterolemia · Hyperglycemia · Insulin blood level · Insulin resistance · Laser Doppler flowmetry · Lipid metabolism · Male · Mouse · Nonhuman · Postoperative period · Blood · Collateral circulation · Comparative study · Experimental diabetes mellitus · Genetics · Growth, development and aging · Metabolism · Mouse strain · Pathophysiology · Physiology · Vascularization · Acute Disease · Animals · Apolipoprotein E3 · Apolipoproteins E · Arteries · Blood Glucose · Cholesterol · Collateral Circulation · Diabetes Mellitus, Experimental · Hindlimb · Hypercholesterolemia · Hyperglycemia · Hyperlipidemias · Insulin · Insulin Resistance · Ischemia · Lipids · Male · Mice · Mice, Inbred Strains · Neovascularization, Physiologic
[Abstract]

16 Acute inhibition of hepatic β-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity
article 2005    
Author: Duivenvoorden, I. · Teusink, B. · Rensen, P.C.N. · Kuipers, F. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Fatty acids · Glucose metabolism · Steatosis · Triglycerides · Very low density lipoprotein · 3 hydroxybutyrate dehydrogenase · carnitine palmitoyltransferase inhibitor · cholesterol · insulin · palmoxiric acid · triacylglycerol · very low density lipoprotein · apolipoprotein E · apolipoprotein E3 · apolipoprotein E3 (Leidein) · fatty acid · messenger RNA · analytic method · animal cell · animal experiment · article · cholesterol blood level · comparative study · controlled study · fatty acid oxidation · gluconeogenesis · insulin blood level · insulin sensitivity · ketogenesis · mouse · nonhuman · transgenic mouse · animal · blood · genetics · insulin resistance · metabolism · oxidation reduction reaction · physiology · secretion · Animals · Apolipoprotein E3 · Apolipoproteins E · Fatty Acids, Nonesterified · Insulin Resistance · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Transgenic · Oxidation-Reduction · RNA, Messenger
[PDF] [Abstract]

17 CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice
article 2003    
Author: Goudriaan, J.R. · Dahlmans, V.E.H. · Teusink, B. · Ouwens, D.M. · Febbraio, M. · Maassen, J.A. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Fatty acid transport · Glucose metabolism · Hepatic steatosis · Hyperinsulinemic clamp · CD36 antigen · fatty acid · glucose · protein kinase B · triacylglycerol · unclassified drug · animal experiment · animal model · animal tissue · controlled study · enzyme activation · enzyme deficiency · fatty acid blood level · glucose blood level · glucose transport · hyperinsulinemia · insulin sensitivity · male · mouse · muscle · nonhuman · spontaneously hypertensive rat · triacylglycerol blood level · Western blotting · wild type · Animals · Antigens, CD36 · Blood Glucose · Body Weight · Eating · Gene Deletion · Insulin · Insulin Resistance · Lipids · Liver · Mice · Mice, Inbred C57BL · Muscle, Skeletal · Rats · Signal Transduction · Triglycerides · Tritium
[PDF] [Abstract]

18 Multi-parameter comparison of a standardized mixed meal tolerance test in healthy and type 2 diabetic subjects: the PhenFlex challenge
article 2017    
Author: Wopereis, S. · Stroeve, J.H.M. · Stafleu, A. · Bakker, G.C.M. · Burggraaf, J. · Erk, M.J. van · Pellis, L. · Boessen, R. · Kardinaal, A.A.F. · Ommen, B. van
Keywords: Nutrition · Nutrition · Phenotypic flexibility · Biomarkers · Nutritional challenge test · Metabolic health · Type 2 diabetes · Glucose · Oral antidiabetic agent · Adipose tissue · Adult · Aged · Clinical article · Controlled study · Crossover procedure · Diabetic patient · Diet restriction · Exploratory research · Glucose metabolism · Health status · Human · Human cell · Human tissue · Intestine tissue · Kidney tissue · Liver tissue · Male · Metabolic parameters · Metabolic regulation · Metabolic stress · Muscle tissue · Non insulin dependent diabetes mellitus · Oral glucose tolerance test · Pancreas tissue · PhenFlex test · Provocation test · Response time · Retrospective study · Standardization · Time factor · Tissue distribution · Vascular tissue · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

19 The Netherlands twin register biobank: A resource for genetic epidemiological studies
article 2010    
Author: Willemsen, G. · Geus, E.J.C. de · Bartels, M. · Beijsterveldt, C.E.M.T. van · Brooks, A.I. · Estourgie-van Burk, G.F. · Fugman, D.A. · Hoekstra, C. · Hottenga, J.-J. · Kluft, K. · Meijer, P. · Montgomery, G.W. · Rizzu, P. · Sondervan, D. · Smit, A.B. · Spijker, S. · Suchiman, H.E.D. · Tischfield, J.A. · Lehner, T. · Slagboom, P.E. · Boomsma, D.I.
Keywords: Biology · Biomedical Research · DNA · GWAS · Mental health · Physical health · RNA · alanine aminotransferase · aspartate aminotransferase · C reactive protein · cholesterol · creatinine · fibrinogen · gamma glutamyltransferase · glucose · hemoglobin · hemoglobin A1c · high density lipoprotein cholesterol · insulin · low density lipoprotein cholesterol · triacylglycerol · adult · alanine aminotransferase blood level · article · aspartate aminotransferase blood level · basophil · blood sampling · body composition · cell line · cholesterol blood level · creatinine blood level · DNA isolation · eosinophil count · erythrocyte count · female · fibrinogen blood level · gamma glutamyl transferase blood level · gene expression · genetic epidemiology · genotype · glucose blood level · glucose metabolism · hematocrit · hemoglobin blood level · heredity · human · insulin blood level · leukocyte count · lifestyle · lipoprotein blood level · lymphocyte count · male · mean corpuscular hemoglobin · mean corpuscular volume · menstrual cycle · mental health · monocyte · Netherlands · Netherlands twin register biobank · neutrophil count · phenotype · priority journal · professional practice · register · single nucleotide polymorphism · thrombocyte count · thrombocyte volume · triacylglycerol blood level · urinalysis
[Abstract]

20 Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice
article 2005    
Author: Heijboer, A.C. · Hoek, A.M. van den · Pijl, H. · Voshol, P.J. · Havekes, L.M. · Romijn, J.A. · Corssmit, E.P.M.
Keywords: Biology · Biomedical Research · Brain · Diabetes · Glut4 · Insulin resistance · Metabolism · Neuropeptides · Glucose transporter 4 · Hormone receptor stimulating agent · Insulin · Melanocortin 3 receptor · Melanocortin 4 receptor · Melanotan II · Messenger RNA · Placebo · Tritium · Unclassified drug · Water · Animal experiment · Animal tissue · Body weight · Brain lateral ventricle · Controlled study · Distillation · Drug effect · Food intake · Gluconeogenesis · Glucose blood level · Glucose clamp technique · Glucose metabolism · Hyperinsulinemia · Insulin sensitivity · Isotope labeling · Mouse · Mouse strain · Nonhuman · Skeletal muscle · Alpha-MSH · Animals · Blood Glucose · Corticosterone · Fatty Acids, Nonesterified · Glucose · Glucose Clamp Technique · Glucose Transporter Type 4 · Injections, Intraventricular · Insulin · Insulin Resistance · Kinetics · Liver · Male · Mice · Mice, Inbred C57BL · Monosaccharide Transport Proteins · Muscle Proteins · Peptides, Cyclic · Receptor, Melanocortin, Type 3 · Receptor, Melanocortin, Type 4 · RNA, Messenger
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 20 found. | Sort by date