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1 Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione
article 1994    
Author: Dirven, H.A.A.M. · Ommen, B. van · Bladeren, P.J. van
Keywords: Biology · Biotransformation · Cyclophosphamide · Glutathione · Glutathione Transferase · Human · Isoenzymes · Phosphoramide Mustards · Support, Non-U.S. Gov't
[Abstract]

2 A glutathione S-transferase with activity towards cis-1,2- dichloroepoxyethane is involved in isoprene utilization by Rhodococcus sp. strain AD45
article 1998    
Author: Hylckama Vlieg, J.E.T. van · Kingma, J. · Wijngaard, A.J. van den · Janssen, D.B.
Keywords: Nutrition · 1,2 dichloroepoxyethane · Ethylene · Glutathione transferase · Industrial chemical · Isoprene · Unclassified drug · Biodegradation · Dechlorination · Detoxification · Enzyme activity · Enzyme isolation · Kinetics · Nonhuman · Biodegradation, Environmental · Butadienes · Epoxy Compounds · Glutathione Transferase · Hemiterpenes · Oxidation-Reduction · Pentanes · Rhodococcus · Negibacteria · Rhodococcus sp.
[PDF] [Abstract]

3 Enzyme kinetics and substrate selectivities of rat glutathione S-transferase isoenzymes towards a series of new 2-substituted 1-chloro-4-nitrobenzenes
article 1996    
Author: Aar, E.M. van der · Buikema, D. · Commandeur, J.N.M. · Koppele, J.M. te · Ommen, B. van · Bladeren, P.J. van · Vermeulen, N.P.E.
Keywords: Nutrition · glutathione transferase · isoenzyme · nitrobenzene derivative · animal tissue · article · controlled study · enzyme kinetics · enzyme specificity · glutathione metabolism · nonhuman · rat · Animals · Chromatography, Affinity · Dinitrochlorobenzene · Glutathione Transferase · Isoenzymes · Kidney · Kinetics · Liver · Rats · Spectrophotometry, Ultraviolet · Substrate Specificity · Animalia · Felis catus
[Abstract]

4 Establishment of the enzymatic protein acetylation independent of acetyl CoA : recombinant glutathione S-transferase 3-3 is acetylated by a novel membrane-bound transacetylane using 7,8-diacetoxy-4-methyl coumarin as the acetyl donor
article 2002    
Author: Kohli, E. · Gaspari, M. · Raj, H.G. · Parmar, V.S. · Greef, J. van der · Gupta, G. · Kumari, R. · Prasad, A.K. · Goel, S. · Pal, G. · Tyagi, K. · Jain, S.C. · Ahmad, N. · Watterson, A.C. · Olsen, C.E.
Keywords: Acetyl Coenzyme A · Acetylation · Acetylesterase · Coumarins · Glutathione Transferase · Recombinant Proteins · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
[PDF] [Abstract]

5 Cigarette smoking and colorectal cancer: APC mutations, hMLH1 expression, and GSTM1 and GSTT1 polymorphisms
article 2005    
Author: Lüchtenborg, M. · Weijenberg, M.P. · Kampman, E. · Muijen, G.N. van · Roemen, G.M.J.M. · Zeegers, M.P.A. · Goldbohm, R.A. · Veer, P. van't · Goeij, A.F.P.M. de · Brandt, P.A. van den
Keywords: Food and Chemical Risk Analysis · Adenomatous polyposis coli · Colorectal neoplasms · Glutathione transferase · Neoplasm proteins · Polymorphism, genetic · Smoking · APC protein · glutathione transferase · glutathione transferase M1 · glutathione transferase T1 · protein MLH1 · unclassified drug · cancer · adult · aged · article · cancer incidence · cancer risk · cigarette smoking · colon polyposis · colorectal cancer · controlled study · female · gene expression · gene mutation · genetic polymorphism · genotype · human · major clinical study · male · Netherlands · polymerase chain reaction · risk assessment · smoking habit · Adenomatous Polyposis Coli · Aged · Carrier Proteins · Colorectal Neoplasms · Confidence Intervals · Diet · Female · Glutathione Transferase · Humans · Incidence · Male · Middle Aged · Neoplasm Proteins · Netherlands · Nuclear Proteins · Polymorphism, Genetic · Prospective Studies · Smoking
[Abstract]

6 Interactions of prostaglandin A2 with the glutathione-mediated biotransformation system
article 1999    
Author: Iersel, M.L.P.S. van · Cnubben, N.H.P. · Smink, N. · Koeman, J.H. · Bladeren, P.J. van
Keywords: Nutrition · Cells · Glutathione S-transferases · Inhibition · Metabolism · Prostaglandin A2 · 1 chloro 2,4 dinitrobenzene · Glutathione · Glutathione transferase · Prostaglandin a2 · Glutathione transferase P1 · GSTP1 protein, human · Isoenzyme · Prostaglandin A · Prostaglandin A2 · Biotransformation · Cell function · Cell metabolism · Cell proliferation · Controlled study · Cytotoxicity · Enzyme activity · Enzyme modification · Human · Human cell · Melanoma cell · Priority journal · Cell culture · Drug antagonism · Melanoma · Metabolism · Biotransformation · Glutathione · Glutathione S-Transferase pi · Glutathione Transferase · Humans · Isoenzymes · Melanoma · Prostaglandins A · Tumor Cells, Cultured
[Abstract]

7 Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans
article 1995    
Author: Nijhoff, W.A. · Grubben, M.J.A.L. · Nagengast, F.M. · Jansen, J.B.M.J. · Verhagen, H. · Poppel, G. van · Peters, W.H.M.
Keywords: Biology · Adult · Brassica · Cross-Over Studies · Duodenum · Energy Intake · Enzyme Induction · Female · Glucosinolates · Glutathione · Glutathione Transferase · Human · Intestines · Isoenzymes · Lymphocytes · Male · Metabolic Detoxication, Drug · Rectum · Thiocyanates
[Abstract]

8 Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin
article 2003    
Author: Zanden, J.J. van · Hamman, O.B. · Iersel, M.L.P.S. van · Boeren, S. · Cnubben, N.H.P. · Lo Bello, M. · Vervoort, J. · Bladeren, P.J. van · Rietjens, I.M.C.M.
Keywords: Biology · Physiological Sciences · Cysteine · Glutathione S-transferase · Inhibition · Quercetin · Quinone · ascorbic acid · cysteine · flavonoid · glutathione · glutathione transferase · isoenzyme · mutant protein · quercetin · article · chemical interaction · concentration response · covalent bond · dimerization · enzyme inhibition · human · incubation time · inhibition kinetics · time · Chromatography, High Pressure Liquid · Dose-Response Relationship, Drug · Glutathione Transferase · Humans · Mass Spectrometry · Molecular Structure · Monophenol Monooxygenase · Mutation · Quercetin
[Abstract]

9 Effects of consumption of Brussels sprouts on plasma and urinary glutathione S-transferase class-α and -π in humans
article 1995    
Author: Nijhoff, W.A. · Mulder, T.P.J. · Verhagen, H. · Poppel, G. van · Peters, W.H.M.
Keywords: glucosinolate · glutathione transferase · adult · article · Brassica · controlled study · diet · enzyme blood level · enzyme linked immunosorbent assay · female · human · male · priority journal · sex difference · urine level · vegetable · Adult · Biological Markers · Brassica · Cross-Over Studies · Diet · Enzyme Induction · Female · Glucosinolates · Glutathione Transferase · Human · Isoenzymes · Male · Sex Factors · Vegetables
[Abstract]

10 Conjugation of isoprene monoepoxides with glutathione, catalyzed by α, μ, π and θ-class glutathione S-transferases of rat and man
article 1999    
Author: Bogaards, J.J.P. · Venekamp, J.C. · Salmon, F.G.C. · Bladeren, P.J. van
Keywords: Nutrition · Glutathione S-transferase · Isoprene · Metabolism · Polymorphism · Cytochrome p450 · Epoxide · Epoxide hydrolase · Glutathione · Glutathione transferase · Isoprene · Conjugate · Conjugation · Controlled study · High performance liquid chromatography · Human · Liver · Liver metabolism · Mouse · Rat · Xenobiotic metabolism · Animals · Chromatography, High Pressure Liquid · Epoxy Compounds · Glutathione · Glutathione Transferase · Humans · Liver · Mice · Rats · Rats, Wistar · Species Specificity · Subcellular Fractions
[Abstract]

11 Basic matrices in the analysis of non-covalent complexes by matrix-assisted laser desorption/ionization mass spectrometry
article 1998    
Author: Jespersen, S. · Niessen, W.M.A. · Tjaden, U.R. · Greef, J. van der
Keywords: Nutrition · Basic matrices · Complex formation · Ionization mass spectrometry · Matrix-assisted laser desorption · Non-covalent interactions · 4 nitroaniline · Cinnamic acid derivative · Gentisic acid · Glutathione transferase · Hemoglobin · Nicotinic acid derivative · Picolinic acid derivative · Protein · Pyridine derivative · Streptavidin · Complex formation · Mass spectrometry · Ph · Priority journal · Chymotrypsinogen · Glutathione Transferase · Hemoglobins · Humans · Hydrogen-Ion Concentration · Indicators and Reagents · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Streptavidin
[Abstract]

12 Glutathione conjugation as a bioactivation reaction
article 2000    
Author: Bladeren, P.J. van
Keywords: Nutrition · Bioactivation · Glutathione conjugates · Glutathione S-transferases · Cysteine · Glutathione · Glutathione transferase · Lyase · Catalysis · Chemical binding · Chemical reaction · Chromosomal localization · Conjugation · Covalent bond · Detoxification · Enzyme activation · Enzyme activity · Enzyme induction · Enzyme inhibition · Enzyme mechanism · Gene location · Genetic polymorphism · Human · Nonhuman · Protein expression · Reaction analysis · Reduction · Animals · Biotransformation · Carbon-Sulfur Lyases · Enzyme Induction · Glutathione · Glutathione Transferase · Humans · Metabolic Detoxication, Drug · Oxidation-Reduction · Xenobiotics
[Abstract]

13 Selection of Arabidopsis mutants overexpressing genes driven by the promoter of an auxin-inducible glutathione S-transferase gene
article 1999    
Author: Kop, D.A.M. van der · Schuyer, M. · Pinas, J.E. · Zaal, B.J. van der · Hooykaas, P.J.J.
Keywords: Nutrition · Arabidopsis thaliana · Auxin-responsive gene expression · Developmental mutants · Glutathione S-transferase · GST · Gup mutant · Auxin · Beta glucuronidase · Gene expression · Glutathione transferase · Kanamycin · Reporter gene · Transgenic plant · Arabidopsis · Chromosome Mapping · Crosses, Genetic · DNA, Bacterial · Enzyme Induction · Ethyl Methanesulfonate · Gene Expression Regulation, Plant · Genes, Plant · Glutathione Transferase · Indoleacetic Acids · Mutagenesis · Mutagens · Mutation · Phenotype · Plants, Genetically Modified · Promoter Regions (Genetics) · Recombinant Fusion Proteins · Up-Regulation
[Abstract]

14 GSTP1-1 stereospecifically catalyzes glutathione conjugation of ethacrynic acid
article 1998    
Author: Iersel, M.L.P.S. van · Lipzig, M.M.H. van · Rietjens, I.M.C.M. · Vervoort, J. · Bladeren, P.J. van
Keywords: EA, ethacrynic acid · Ethacrynic acid · Glutathione S-transferase · Stereoselectivity · Etacrynic acid · Glutathione · Glutathione transferase · Multidrug resistance protein · Chemical reaction · Conjugate · Controlled study · Diastereoisomer · Drug conjugation · Enzyme mechanism · Glutathione metabolism · Human cell · Melanoma cell · Nuclear magnetic resonance spectroscopy · Stereochemistry · Amino Acid Substitution · Ethacrynic Acid · Glutathione · Glutathione Transferase · Humans · Isoenzymes · Melanoma · Point Mutation · Stereoisomerism · Substrate Specificity · Tumor Cells, Cultured
[PDF] [Abstract]

15 The role of biotransformation in dietary (anti)carcinogenesis
article 1999    
Author: Iersel, M.L.P.S. van · Verhagen, H. · Bladeren, P.J. van
Keywords: Nutrition · (Anti)carcinogenic · Biotransformation · Dietary compound · Modulation · Cytochrome p450 · Glutathione transferase · Biotransformation · Cancer risk · Carcinogenesis · Drug detoxification · Enzyme activity · Genetic polymorphism · Human · Nutrition · Priority journal · Review · Biotransformation · Carcinogens · Cytochrome P-450 Enzyme System · Diet · Gene Expression Regulation, Neoplastic · Glutathione Transferase · Humans · Kinetics · Neoplasms · Variation (Genetics) · Xenobiotics
[Abstract]

16 Effect of short-term dietary administration of eugenol in humans
article 1996    
Author: Rompelberg, C.J.M. · Vogels, J.T.W.E. · Vogel, N. de · Bruijntjes-Rozier, G.C.D.M. · Stenhuis, W.H. · Bogaards, J.J.P. · Verhagen, H.
Keywords: Nutrition · Antigenotoxicity · Eugenol · GST · antitoxin · eugenol · glutathione transferase · mitomycin c · vinblastine · article · biotransformation · blood sampling · chromosome aberration · controlled study · enzyme activity · erythrocyte · genotoxicity · human · human experiment · leukocyte · male · micronucleus · priority journal · xenobiotic metabolism · Acetaminophen · Adult · Antibiotics, Antineoplastic · Antineoplastic Agents, Phytogenic · Biotransformation · Cells, Cultured · Chromosome Aberrations · Cross-Over Studies · Erythrocytes · Eugenol · Glutathione Transferase · Humans · Intervention Studies · Leukocytes · Liver · Magnetic Resonance Spectroscopy · Male · Mitomycin · Vinblastine
[Abstract]

17 Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases
article 1995    
Author: Dirven, H.A.A.M. · Megens, L. · Oudshoorn, M.J. · Dingemanse, M.A. · Ommen, B. van · Bladeren, P.J. van
Keywords: Nutrition · Glutathione · Glutathione transferase · Ifosfamide · Cancer chemotherapy · Drug conjugation · Drug detoxification · Drug resistance · Enzyme activity · Human · Human tissue · Leukemia · Lymphoma · Solid tumor · Antineoplastic Agents, Alkylating · Biotransformation · Chromatography, High Pressure Liquid · Drug Resistance, Neoplasm · Glutathione · Glutathione Transferase · Human · Ifosfamide · Isoenzymes · Magnetic Resonance Spectroscopy · Metabolic Detoxication, Drug · Spectrometry, Mass, Fast Atom Bombardment · Support, Non-U.S. Gov't
[Abstract]

18 Effect of a vegan diet on biomarkers of chemoprevention in females
article 1996    
Author: Verhagen, H. · Rauma, A.L. · Törrönen, R. · Vogel, N. de · Bruijntjes-Rozier, G.C.D.M. · Dreve, M.A. · Bogaards, J.J.P. · Mykkänen, H.
Keywords: Nutrition · Adult · Aged · Aging · Antibiotics, Antineoplastic · Cells, Cultured · Chemoprevention · Cross-Sectional Studies · Diet, Vegetarian · DNA Damage · DNA, Single-Stranded · Electrophoresis · Erythrocytes · Female · Glutathione Transferase · Humans · Leukocytes · Micronuclei, Chromosome-Defective · Middle Aged · Mitomycin · Superoxide Dismutase
[Abstract]

19 Inhibition of rat, mouse, and human glutathione S-transferase by eugenol and its oxidation products
article 1996    
Author: Rompelberg, C.J.M. · Ploemen, J.H.T.M. · Jespersen, S. · Greef, J. van der · Verhagen, H. · Bladeren, P.J. van
Keywords: Nutrition · Allyl Compounds · Animals · Cytoplasm · Eugenol · Glutathione Transferase · Humans · Isoenzymes · Kidney · Liver · Male · Mice · Molecular Structure · Monophenol Monooxygenase · Phenols · Placenta · Rats · Rats, Wistar · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Animalia
[Abstract]

20 Identification of multiple target sites for a glutathione conjugate on glutathione-S-transferase by matrix-assisted laser desorption/ionization mass spectrometry
article 1996    
Author: Jespersen, S. · Ploemen, J.H.T.M. · Bladeren, P.J. · Niessen, W.M.A. · Tjaden, U.R. · Greef, J. van der
Keywords: Nutrition · GSTCBQ target residues · Mapping site-specific mutagenesis · Binding Sites · Chloranil · Enzyme Inhibitors · Glutathione · Glutathione Transferase · Molecular Weight · Mutagenesis, Site-Directed · Peptide Mapping · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 47 found. Next | Sort by date