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1 Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158→Cys) homozygotes is associated with hyperinsulinemia
article 2002    
Author: Beer, F. de · Stalenhoef, A.F.H. · Hoogerbrugge, N. · Kastelein, J.J.P. · Leuven, J.A.G. · Duijn, C.M. van · Havekes, L.M. · Smelt, A.H.M.
Keywords: Adult · Age of Onset · Aging · Apolipoprotein E2 · Apolipoproteins E · Comorbidity · Coronary Disease · Estrogens · Female · Gene Expression · Gene Frequency · Homozygote · Humans · Hyperinsulinism · Hyperlipoproteinemia Type III · Male · Menopause · Middle Aged · Netherlands · Peripheral Vascular Diseases · Prevalence · Regression Analysis · Sex Factors
[Abstract]

2 Dynamics of insulin signalling in liver during hyperinsulinemic euglycaemic clamp conditions in vivo and the effects of high-fat feeding in male mice
article 2007    
Author: Korsheninnikova, E. · Voshol, P.J. · Baan, B. · Zon, G.C.M. van der · Havekes, L.M. · Romijn, J.A. · Maassen, J.A. · Ouwens, D.M.
Keywords: Biology · Biomedical Research · Hepatic glucose production · High-fat diet · Insulin resistance · Insulin signalling · Liver · glucose · insulin · insulin receptor · phosphatidylinositol 3 kinase · protein kinase B · animal · article · blood · C57BL mouse · drug effect · fat intake · gene expression regulation · glucose clamp technique · hyperinsulinism · liver · male · metabolism · mouse · signal transduction · 1-Phosphatidylinositol 3-Kinase · Animals · Dietary Fats · Gene Expression Regulation, Enzymologic · Glucose · Glucose Clamp Technique · Hyperinsulinism · Insulin · Liver · Male · Mice · Mice, Inbred C57BL · Proto-Oncogene Proteins c-akt · Receptor, Insulin · Signal Transduction · Mus
[Abstract]

3 Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation
article 2008    
Author: Hoek, A.M. van den · Heijningen, C. van · Schröder - Elst, J.P. van der · Ouwens, D.M. · Havekes, L.M. · Romijn, J.A. · Kalsbeek, A. · Pijl, H.
Keywords: corticosterone · glucose · insulin · liothyronine · neuropeptide Y · testosterone · thyroxine · antidiabetic agent · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · glucose metabolism · hormone blood level · insulin resistance · liver · male · nonhuman · parasympathetic innervation · priority journal · rat · sympathetic innervation · adrenergic system · animal · drug effect · glucose blood level · glucose clamp technique · hyperinsulinism · innervation · intracerebroventricular drug administration · metabolism · pathophysiology · physiology · sympathectomy · vagotomy · Wistar rat · Animals · Blood Glucose · Glucose Clamp Technique · Hyperinsulinism · Hypoglycemic Agents · Injections, Intraventricular · Insulin · Insulin Resistance · Liver · Male · Neuropeptide Y · Parasympathectomy · Rats · Rats, Wistar · Sympathectomy · Sympathetic Nervous System
[Abstract]

4 Severe hyperlipidemia in apolipoprotein E2 homozygotes due to a combined effect of hyperinsulinemia and an SstI polymorphism
article 1999    
Author: Sijbrands, E.J.G. · Hoffer, M.J.V. · Meinders, A.E. · Havekes, L.M. · Frants, R.R. · Smelt, A.H.M. · Knijff, P. de
Keywords: Apolipoprotein E · Hyperinsulinemia · Hyperlipoproteinemia type III · Xanthomas · Adult · Aged · Aged, 80 and over · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoprotein E2 · Apolipoproteins A · Apolipoproteins C · Apolipoproteins E · Cholesterol, HDL · Cholesterol, LDL · Cholesterol, VLDL · Family Health · Female · Gene Expression · Haplotypes · Homozygote · Humans · Hyperinsulinism · Hyperlipidemias · Male · Middle Aged · Pedigree · Polymorphism, Single Nucleotide · Promoter Regions (Genetics) · Xanthomatosis
[Abstract]

5 Glycemic load, glycemic index, and pancreatic cancer risk in the Netherlands Cohort Study
article 2008    
Author: Heinen, M.M. · Verhage, B.A.J. · Lumey, L.H. · Brants, H.A.M. · Goldbohm, R.A. · Brandt, P.A. van den
Keywords: carbohydrate · disaccharide · monosaccharide · adult · aged · anamnesis · article · cancer diagnosis · cancer risk · carbohydrate intake · cohort analysis · controlled study · diabetes mellitus · female · follow up · glycemic index · glycemic load · human · major clinical study · male · microscopy · Netherlands · nutritional assessment · pancreas cancer · prospective study · questionnaire · Aged · Blood Glucose · Cohort Studies · Diet · Dietary Carbohydrates · Female · Follow-Up Studies · Glycemic Index · Humans · Hyperinsulinism · Insulin · Male · Middle Aged · Netherlands · Pancreatic Neoplasms · Prospective Studies · Questionnaires · Risk Factors
[Abstract]

6 Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance
article 2004    
Author: Muurling, M. · Hoek, A.M. van den · Mensink, R.P. · Pijl, H. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Free fatty acid metabolism · Hepatic fat accumulation · Lipid metabolism · Peroxisome proliferator-activated receptor-γ · Rosiglitazone · Diacylglycerol · Glucose · Ketone body · Peroxisome proliferator activated receptor gamma · Rosiglitazone · Triacylglycerol · Adipose tissue · Animal experiment · Animal model · Animal tissue · APOC1 gene · Cholesterol blood level · Controlled study · Fatty acid metabolism · Gene · Gene overexpression · Gluconeogenesis · Glucose blood level · Glucose transport · Hyperglycemia · Hyperinsulinemia · Hyperlipidemia · Insulin blood level · Insulin resistance · Lipid metabolism · Lipid storage · Mouse · Nonhuman · Obesity · Transgenic mouse · Triacylglycerol blood level · Weight reduction · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Body Weight · Fatty Acids · Fatty Liver · Gene Expression · Humans · Hyperglycemia · Hyperinsulinism · Hyperlipidemias · Insulin · Insulin Resistance · Mice · Mice, Transgenic
[PDF] [Abstract]

7 Effect of Moderate Alcohol Consumption on Adiponectin, Tumor Necrosis Factor-α, and Insulin Sensitivity
article 2004    
Author: Sierksma, A. · Patel, H. · Ouchi, N. · Kihara, S. · Funahashi, T. · Heine, R.J. · Grobbee, D.E. · Kluft, C. · Hendriks, H.F.J.
Keywords: Health · Physiological Sciences · Adiponectin · C peptide · Cholesterol · Cytokine · Fatty acid · Glucose · High density lipoprotein cholesterol · Insulin · Insulin receptor · Low density lipoprotein cholesterol · Tap water · Triacylglycerol · Tumor necrosis factor alpha · Adipose tissue · Adult · Alcohol consumption · Cholesterol blood level · Clinical trial · Controlled study · Crossover procedure · Diabetes mellitus · Diet restriction · Glucose blood level · Insulin sensitivity · Non insulin dependent diabetes mellitus · Normal human · Randomized controlled trial · Risk factor · Whiskey · Adiponectin · Aged · Alcohol Drinking · Body Mass Index · Body Weight · Cross-Over Studies · Glucose Clamp Technique · Humans · Hyperinsulinism · Insulin · Insulin Resistance · Intercellular Signaling Peptides and Proteins · Male · Middle Aged · Proteins · Regression Analysis · Tumor Necrosis Factor-alpha
[Abstract]

8 CNTO736, a novel glucagon-like peptide-1 receptor agonist, ameliorates insulin resistance and inhibits very low-density lipoprotein production in high-fat-fed mice
article 2009    
Author: Parlevliet, E.T. · Schröder-van der Elst, J.P. · Corssmit, E.P.M. · Picha, K. · O'Neil, K. · Stojanovic-Susulic, V. · Ort, T. · Havekes, L.M. · Romijn, J.A. · Pijl, H.
Keywords: Biology · Biomedical Research · CNTO 736 · exendin 4 · glucagon like peptide 1 derivative · glucagon like peptide 1 receptor · very low density lipoprotein · glucagon like peptide receptor · glucagon receptor · glucagon-like peptide receptor · hybrid protein · triacylglycerol · animal experiment · animal model · chronic drug administration · controlled study · gluconeogenesis · glucose blood level · glucose transport · hyperinsulinemia · lipid diet · lipoprotein metabolism · male · mouse · nonhuman · single drug dose · animal food · blood · C57BL mouse · Cytomegalovirus · Drug effect · Drug potentiation · Fat intake · Genetics · Intravenous drug administration · Metabolism · Molecular cloning · Animal Feed · Animals · Blood Glucose · Cloning, Molecular · Cytomegalovirus · Dietary Fats · Glucose · Glucose Clamp Technique · Hyperinsulinism · Infusions, Intravenous · Insulin · Insulin Resistance · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Promoter Regions, Genetic · Receptors, Glucagon · Recombinant Fusion Proteins · Triglycerides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date