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1 Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm doxycycline selectively depletes aortic wall neutrophils and cytotoxic t cells
article 2009    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Bockel, J.H. van · Wolterbeek, R. · Kleemann, R.
Keywords: Health · Aneurysm · Immunology · Inflammation · Molecular biology · Trials · Doxycycline · Gelatinase B · Granulocyte colony stimulating factor receptor · Interleukin 13 · Interleukin 6 · Interleukin 8 · Antiinfective agent · CCAAT enhancer binding protein · Enzyme inhibitor · IL6 protein, human · Transcription factor AP 1 · Transcription factor RelA · Abdominal aorta aneurysm · Aged · Cytotoxic T lymphocyte · Drug effect · Drug megadose · Drug tolerability · Enzyme inhibition · Aortic Aneurysm, Abdominal · CCAAT-Enhancer-Binding Proteins · Doxycycline · Enzyme Inhibitors · Matrix Metalloproteinase 9 · Middle Aged · Neutrophils · T-Lymphocytes, Cytotoxic · Vasculitis
[PDF] [Abstract]

2 Innate, adaptive and regulatory responses in schistosomiasis: Relationship to allergy
article 2006    
Author: Hartgers, F.C. · Smits, H.H. · Kleij, D. van der · Yazdanbakhsh, M.
Keywords: Anthelmintic agent · Immunoglobulin G4 · Intercellular adhesion molecule 3 · Interleukin 13 receptor · Pattern recognition receptor · STAT1 protein · Tetanus toxoid · Toll like receptor 1 · Toll like receptor 3 · Toll like receptor 5 · Toll like receptor 6 · Toll like receptor 7 · Toll like receptor 8 · Allergy · Antibody production · Antigen specificity · Atopy · Brugia malayi · CD4+ CD25+ T lymphocyte · Cellular immunity · Chronic disease · Clonal anergy · Cross tolerance · Dendritic cell · Down regulation · Endemic disease · Helicobacter pylori · Helminthiasis · Human · Immune deficiency · Immune response · Immunoregulation · Inflammation · Innate immunity · Lymphocyte proliferation · Mast cell degranulation · Molecular interaction · Nippostrongylus brasiliensis · Nonhuman · Regulatory T lymphocyte · Review · Schistosoma · Schistosoma hematobium · Schistosoma mansoni · Schistosomiasis · Sensitization · T lymphocyte activation · T lymphocyte subpopulation · Tetanus · Th1 cell · Th2 cell · Upregulation · Animals · Chronic Disease · Hypersensitivity · Immune Tolerance · Immunity, Natural · Interleukin 13, 148157-34-0 · Tetanus toxoid, 57425-69-1, 93384-51-1 · Toll like receptor 2, 203811-81-8 · Toll like receptor 4, 203811-83-0 · Toll like receptor 9, 352486-49-8, 390883-32-6 · Toll like receptor, 409141-78-2
[Abstract]

3 Developmental immunotoxicity of methylmercury: The relative sensitivity of developmental and immune parameters
article 2010    
Author: Tonk, E.C.M. · Groot, D.M.G. de · Penninks, A.H. · Waalkens - Berendsen, I.D.H. · Wolterbeek, A.P.M. · Slob, W. · Piersma, A.H. · Loveren, H. van
Keywords: Toxicology · Biomedical Research · Benchmark dose · Developmental immunotoxicity · Developmental toxicity · Dose-response modeling · Methylmercury · Perinatal exposure · Rat · gamma interferon · interleukin 10 · interleukin 13 · interleukin 2 · interleukin 4 · interleukin 6 · keyhole limpet hemocyanin · methylmercury · T lymphocyte antibody · adherent cell · animal tissue · antibody response · article · basophil · body weight · CD3+ T lymphocyte · CD4 CD8 ratio · CD8+ T lymphocyte · clinical evaluation · controlled study · cytokine production · delayed hypersensitivity · developmental screening · diagnostic value · environmental exposure · epididymis · erythrocyte · female · gestational age · immunological parameters · immunotoxicity · kidney mass · leukocyte count · litter size · liver weight · lymphocyte proliferation · natural killer cell · newborn mortality · nonhuman · rat · reticulocyte count · sensitivity and specificity · spleen cell · spleen weight · stillbirth · testis weight · thrombocyte count · thymus · weight reduction
[Abstract]

4 αB-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions
article 2010    
Author: Noort, J.M. van · Bsibsi, M. · Gerritsen, W.H. · Valk, P. van der · Bajramovic, J.J. · Steinman, L. · Amor, S.
Keywords: Biology · Biomedical Research · αB-crystallin · Autoantibodies · Microglia · Multiple sclerosis · Preactive lesions · alpha B crystallin · antibody · CCL1 chemokine · chemokine · crystallin · HLA DR antigen · immunoglobulin G · interleukin 10 · interleukin 13 · interleukin 17 · myelin protein · transforming growth factor beta · tumor necrosis factor · unclassified drug · alpha crystallin · basic helix loop helix transcription factor · cytokine · glial fibrillary acidic protein · nerve protein · neurofilament protein · neurofilament protein L · OLIG2 protein, human · proteolipid protein · adaptive immunity · adult · antibody blood level · article · cell activation · clinical article · controlled study · human · immunoglobulin blood level · innate immunity · male · microglia · multiple sclerosis · priority journal · protein secretion · white matter · immunology · mass spectrometry · metabolism · methodology · middle aged · oligodendroglia · pathology · pathophysiology · physiology · Adaptive Immunity · Adult · alpha-Crystallins · Basic Helix-Loop-Helix Transcription Factors · Cytokines · Glial Fibrillary Acidic Protein · HLA-DR Antigens · Humans · Mass Spectrometry · Microglia · Middle Aged · Multiple Sclerosis · Myelin Proteolipid Protein · Nerve Tissue Proteins · Neurofilament Proteins · Oligodendroglia
[Abstract]

5 Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurysmal from atherosclerotic aorta: IL-6- and IL-8-dominated inflammatory responses prevail in the human aneurysm
article 2008    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Schaapherder, A.F.M. · Bockel, J.H. van · Thüsen, J.H. vonder · Roelen, D.L. · Kleemann, R.
Keywords: Health · Abdominal aortic aneurysm · Atherosclerosis · Inflammation · Interleukin · Transcription factor · CCAAT enhancer binding protein alpha · CCAAT enhancer binding protein beta · CCAAT enhancer binding protein delta · Cytokine · Gamma interferon · Interleukin 10 · Interleukin 13 · Interleukin 1alpha · Interleukin 2 · Interleukin 4 · Interleukin 6 · Interleukin 8 · Messenger RNA · Perforin · STAT3 protein · transcription factor · transcription factor AP 1 · transcription factor GATA 3 · transcription factor RelA · transcription factor T bet · tumor necrosis factor alpha · autacoid · biological marker · abdominal aorta aneurysm · adult · aged · aorta atherosclerosis · aorta wall · B lymphocyte · Cellular immunity · Clinical article · Controlled study · Cytotoxic T lymphocyte · Enzyme linked immunosorbent assay · Female · Human · Human tissue · Immunohistochemistry · Male · Medical parameters · Neutrophil · Plasma cell · Protein expression · Real time polymerase chain reaction · Th1 cell · Th2 cell · Vasa vasorum · Western blotting · Aorta valve stenosis · Biosynthesis · Differential diagnosis · Genetics · Immunology · Metabolism · Methodology · Physiology · Reverse transcription polymerase chain reaction · Aged · Aortic Aneurysm, Abdominal · Aortic Valve Stenosis · Atherosclerosis · Biological Markers · Diagnosis, Differential · Female · Gene Expression Profiling · Humans · Inflammation Mediators · Male · Middle Aged · Reverse Transcriptase Polymerase Chain Reaction · Th1 Cells · Th2 Cells · Transcription Factors
[Abstract]

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