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1 Germ cell mutagenesis in lambdalacZ transgenic mice treated with ethylnitrosourea : comparison with specific-locus test
article 1995    
Author: Delft, J.H.M. van · Baan, R.A.
Keywords: Biology · Animal · Comparative Study · DNA · Dose-Response Relationship, Drug · Ethylnitrosourea · Guanidine · Guanidines · Lac Operon · Male · Mice · Mice, Transgenic · Mutagenesis · Mutagenicity Tests · Spermatogenesis · Spermatozoa · Support, Non-U.S. Gov't · Time Factors
[Abstract]

2 DNA adducts, mutant frequencies and mutation spectra in λlacZ transgenic mice treated with N-nitrosodimethylamine
article 1998    
Author: Souliotis, V.L. · Delft, J.H.M. van · Steenwinkel, M.-J.S.T. · Baan, R.A. · Kyrtopoulos, S.A.
Keywords: Nutrition · 6 o alkylguanine dna alkyltransferase · 6 o methylguanine · 7 methylguanine · Beta galactosidase · Dimethylnitrosamine · Dna · Animal experiment · Animal tissue · Carcinogenesis · Controlled study · Dna adduct · Liver · Male · Mouse · Mutation rate · Nonhuman · Priority journal · Spleen · Transgenic mouse · Animals · Carcinogens · Dimethylnitrosamine · DNA Adducts · Lac Operon · Male · Mice · Mice, Transgenic · Mutagens · Mutation · Sequence Deletion
[Abstract]

3 Induction of somatic mutations but not methylated DNA adducts in λlacZ transgenic mice by dichlorvos
article 1999    
Author: Pletsa, V. · Steenwinkel, M.-J.S.T. · Delft, J.H.M. van · Baan, R.A. · Kyrtopoulos, S.A.
Keywords: Nutrition · Dimethylsulphate · Methylating agents · N7-Methylguanine · O6-Methylguanine · Organosphosphate insecticides · 6 o methylguanine · 7 methylguanine · Dichlorvos · Dimethyl sulfate · Animal cell · Bone marrow cell · Controlled study · DNA adduct · DNA methylation · Genotoxicity · Liver cell · Mouse · Mutation rate · Nonhuman · Priority journal · Somatic mutation · Transgenic mouse · Animals · Dichlorvos · DNA Methylation · Guanine · Insecticides · Lac Operon · Mice · Mice, Transgenic · Mutation · Mus musculus
[Abstract]

4 Influence of nucleotide excision repair on N-hydroxy-2-acetylaminofluorene-induced mutagenesis studied in λlacZ-transgenic mice
article 1998    
Author: Frijhoff, A.F.W. · Krul, C.A.M. · Vries, A. de · Kelders, M.C.J.M. · Weeda, G. · Steeg, H. van · Baan, R.A.
Keywords: Nutrition · LacZ · Mutagenesis · N-hydroxy-2-acetylaminofluorene · Nucleotide excision repair · Transgenic mice · Fluorenylacetohydroxamic acid · Nucleotide · Animal experiment · Controlled study · Dna sequence · Excision repair · Female · Male · Mouse · Mutagenesis · Mutagenicity · Mutation rate · Nonhuman · Spontaneous mutation · Transgenic mouse · Animals · DNA Repair · DNA-Binding Proteins · Endonucleases · Hydroxyacetylaminofluorene · Lac Operon · Male · Mice · Mice, Transgenic · Mutagens · Proteins
[Abstract]

5 Effect of eugenol on the mutagenicity of benzo[a]pyrene and the formation of benzo[a]pyrene-DNA adducts in the X-lacZ-transgenic mouse.
article 1996    
Author: Rompelberg, C.J.M. · Steenwinkel, M.J.S.T. · Asten, J.G. van · Delft, J.H.M. van · Baan, R.A. · Verhagen, H.
Keywords: Toxicology · Antimutagenicity · Benzo[a]pyrene · DNA adduct · Eugenol · Transgenic mouse · benzo[a]pyrene · eugenol · animal experiment · article · controlled study · dna adduct · genotoxicity · male · mouse · mutagenicity · mutation rate · nonhuman · oral drug administration · priority journal · transgenic mouse · Animals · Antimutagenic Agents · Benzo(a)pyrene · Biotransformation · Body Weight · Diet · DNA Adducts · Eugenol · Glutathione Transferase · Lac Operon · Liver · Male · Mice · Mice, Transgenic · Mutagens · Phosphorus Radioisotopes · Animalia · Gale · Mus musculus
[Abstract]

6 Gene-mutation assays in lambda-lacZ transgenic mice : comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium
article 1998    
Author: Delft, J.H.M. van · Bergmans, A. · Dam, F.J. van · Tates, A.D. · Howard, L. · Winton, D.J. · Baan, R.A.
Keywords: Biology · λlacZ · Dlb-1 · hprt · Mutagenesis · Transgenic mouse · ethylnitrosourea · hypoxanthine phosphoribosyltransferase · mesylic acid ethyl ester · methylnitrosourea · mutagenic agent · animal cell · animal experiment · animal tissue · article · controlled study · gene · gene mutation · intestine epithelium · mouse · mutagenesis · mutagenicity · nonhuman · priority journal · small intestine mucosa · spleen cell · transgenic mouse · Alkylating Agents · Animals · Ethyl Methanesulfonate · Ethylnitrosourea · Genetic Markers · Hypoxanthine Phosphoribosyltransferase · Intestinal Mucosa · Intestine, Small · Lac Operon · Methylnitrosourea · Mice · Mice, Inbred C57BL · Mice, Transgenic · Mutagenicity Tests · Mutagens · Mutation · Spleen · Animalia · Mus musculus
[Abstract]

7 DNA adducts, mutant frequencies, and mutation spectra in various organs of λlacZ mice exposed to ethylating agents
article 1998    
Author: Mientjes, E.J. · Luiten-Schuite, A. · Wolf, E. van der · Borsboom, Y. · Bergmans, A. · Berends, F. · Lohman, P.H.M. · Baan, R.A. · Delft, J.H.M. van
Keywords: Nutrition · λlacZ transgenic mice · Ethyl DNA adducts · Muta(TM)Mouse · Mutagenesis · Mutation spectra · Alkylating agent · Diethylnitrosamine · Ethylnitrosourea · Guanine derivative · Mesylic acid ethyl ester · Animal experiment · Animal tissue · Bone marrow · Brain · Controlled study · Dna adduct · Female · Liver · Mouse · Mutagenesis · Mutation · Mutation rate · Nonhuman · Sequence analysis · Transgenic mouse · Animals · Bone Marrow · Brain · Diethylnitrosamine · DNA Adducts · Ethyl Methanesulfonate · Ethylnitrosourea · Female · Guanine · Lac Operon · Liver · Mice · Mice, Transgenic · Mutagens
[Abstract]

8 Methyl bromide causes DNA methylation in rats and mice but fails to induce somatic mutations in λlacZ transgenic mice
article 1998    
Author: Pletsa, V. · Steenwinkel, M.-J.S.T. · Delft, J.H.M. van · Baan, R.A. · Kyrtopoulos, S.A.
Keywords: Nutrition · Methylating agents · N7-methylguanine · O6-Alkylguanine-DNA alkyltransferase · O6-Methylguanine · Pesticides · Somatic mutation · 6 o alkylguanine DNA alkyltransferase · 6 o methylguanine · 7 methylguanine · Methyl bromide · Pesticide · Animal cell · Animal experiment · Bone marrow · Controlled study · DNA adduct · DNA methylation · Female · Gene mutation · Mouse · Nonhuman · Priority journal · Somatic mutation · Stomach · Tissue distribution · Transgenic mouse · Animals · DNA Adducts · DNA Methylation · Dose-Response Relationship, Drug · Guanine · Hydrocarbons, Brominated · Lac Operon · Male · Mice · Mice, Transgenic · Mutagenesis · Mutagens · O(6)-Methylguanine-DNA Methyltransferase · Rats · Rats, Sprague-Dawley · Mus musculus
[Abstract]

9 Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons
article 2000    
Author: Kappers, W.A. · Och, F.M.M. van · Groene, E.M. de · Horbach, G.J.
Keywords: Nutrition · Acetyltransferase · Amestest · AminoPAHs · Cytochrome P450 · HPRT · Mutagenicity · NIH/3T3 cells · NitroPAHs · Shuttle vector · V79 cells · Cytochrome P450 · Polycyclic aromatic hydrocarbon · Animal cell · Cell strain 3T3 · Controlled study · Enzyme activity · Gene locus · In vitro study · Mouse · Mutagenicity · Nonhuman · Priority journal · Reaction analysis · Reporter gene · Shuttle vector · 3T3 Cells · Animals · Cell Line · Cell Survival · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Enzyme Inhibitors · Ethyl Methanesulfonate · Fluorenes · Humans · Hypoxanthine Phosphoribosyltransferase · Ketoconazole · Lac Operon · Mice · Microsomes, Liver · Mutagenicity Tests · Mutagens · Mutation · Polycyclic Hydrocarbons, Aromatic · Pyrenes · Rats · Recombinant Fusion Proteins · Salmonella typhimurium · Theophylline · Animalia · Cricetinae · Cricetulus griseus · Eukaryota · Salmonella typhimurium · Typhimurium
[Abstract]

10 Formation and persistence of O6-ethylguanine in genomic and transgene DNA in liver and brain of λlacZ transgenic mice treated with N-ethyl-N-nitrosourea
article 1996    
Author: Mientjes, E.J. · Hochleitner, K. · Luiten-Schuite, A. · Delft, J.H.M. van · Thomale, J. · Berends, F. · Rajewsky, M.F. · Lohman, P.H.M. · Baan, R.A.
Keywords: Toxicology · 6 o alkylguanine dna alkyltransferase · dna · ethylnitrosourea · guanine derivative · 6 ethylguanine · 6-ethylguanine · 7 ethylguanine · 7-ethylguanine · DNA · drug derivative · guanine · mutagenic agent · animal experiment · animal tissue · article · brain · controlled study · dna adduct · dna repair · enzyme inhibition · female · immunoblotting · liver · mouse · mutagenicity · nonhuman · priority journal · transgene · transgenic mouse · animal · bacteriophage lambda · biosynthesis · DNA repair · drug effect · genetics · genome · lactose operon · metabolism · mutagen testing · physiology · polymerase chain reaction · sensitivity and specificity · Animals · Bacteriophage lambda · Brain · DNA · DNA Repair · Ethylnitrosourea · Female · Genome · Guanine · Immunoblotting · Lac Operon · Liver · Mice · Mice, Transgenic · Mutagenicity Tests · Mutagens · Polymerase Chain Reaction · Sensitivity and Specificity
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 10 of 10 found. | Sort by date