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1 CD40 in clinical inflammation: From multiple sclerosis to atherosclerosis
article 1998    
Author: Laman, J.D. · Boer, M. de · Hart, B.A. 't
Keywords: Health · Accessory molecules · Costimulation · Immunocytochemistry · Macrophages · Animals · Antigen-Presenting Cells · Antigens, CD40 · Arteriosclerosis · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Humans · Membrane Glycoproteins · Multiple Sclerosis · T-Lymphocytes
[Abstract]

2 CD40-CD40L interactions in atherosclerosis
article 1997    
Author: Laman, J.D. · Meurs, M. van · Smet, B.J.G.L. de · Schoneveld, A.
Keywords: Health · Cd40 antigen · Glycoprotein gp 39 · Atherosclerotic plaque · Immunology · T lymphocyte activation · Animals · Antigens, CD40 · Arteriosclerosis · CD40 Ligand · Humans · Ligands · Membrane Glycoproteins · Protein Binding
[Abstract]

3 gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory
article 1994    
Author: Foy, T.M. · Laman, J.D. · Ledbetter, J.A. · Aruffo, A. · Claassen, E. · Noelle, R.J.
Keywords: cd4 antigen · Ligand · Antibody production · Antibody response · Antigen specificity · Cell maturation · Germinal center · Helper cell · Humoral immunity · Immune response · Immunization · Immunohistochemistry · Memory cell · Mouse · Animal · Antibody Formation · Antigens, CD · Antigens, CD40 · B-Lymphocytes · CD40 Ligand · Immunologic Memory · Membrane Glycoproteins · Mice · Mice, Inbred BALB C
[Abstract]

4 CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms
article 2007    
Author: Kraaijeveld, A.O. · Jager, S.C.A. de · Jager, W.J. de · Prakken, B.J. · McColl, S.R. · Haspels, I. · Putter, H. · Berkel, T.J.C. van · Nagelkerken, L. · Jukema, J.W. · Biessen, E.A.L.
Keywords: Atherosclerosis · Chemokines · Ischemia · Leukocytes · Ligands · C reactive protein · CD40 ligand · RANTES · Aged · Angina, Unstable · Atherosclerosis · C-Reactive Protein · CD40 Ligand · Chemokine CCL5 · Chemokines, CC · Clinical Trials as Topic · Cohort Studies · Female · Humans · Leukocytes, Mononuclear · Male · Middle Aged · Myocardial Ischemia · Prospective Studies · Receptors, CCR · Regeneration
[Abstract]

5 FcR interactions do not play a major role in inhibition of experimental autoimmune encephalomyelitis by anti-CD154 monoclonal antibodies
article 2004    
Author: Nagelkerken, L. · Haspels, I. · Rijs, W. van · Blauw, B. · Ferrant, J.L. · Hess, D.M. · Garber, E.A. · Taylor, F.R. · Burkly, L.C.
Keywords: CD40 ligand monoclonal antibody · allergic encephalomyelitis · allotransplantation · animal cell · animal experiment · animal model · cell infiltration · complement fixation · controlled study · fluorescence activated cell sorting · glycosylation · immunoreactivity · lymphocyte depletion · mouse · nonhuman · Th1 cell · Animals · Antibodies, Monoclonal · B-Lymphocytes · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Female · Glycosylation · Mice · Myelin Proteolipid Protein · Peptide Fragments · Receptors, Fc · T-Lymphocytes
[Abstract]

6 The development of clinical activity in relapsing-remitting MS is associated with a decrease of FasL mRNA and an increase of Fas mRNA in peripheral blood
article 2003    
Author: Lopatinskaya, L. · Boxel van-Dezaire, A.H.H. · Barkhof, F. · Polman, C.H. · Lucas, C.J. · Nagelkerken, L.
Keywords: Health · CCR3 · CCR5 · CXCR3 · Fas (Apo-1, CD95) · Fas Ligand (CD95L, CD178) · Chemokine receptor CCR3 · Chemokine receptor CCR5 · Chemokine receptor CXCR3 · Fas antigen · FAS ligand · Messenger RNA · Blood · Cell migration · Central nervous system · Clinical article · Controlled study · Disease activity · Disease exacerbation · Inflammatory cell · Mononuclear cell · Multiple sclerosis · Protein expression · Adult · Antigens, CD95 · Apoptosis · Cross-Sectional Studies · Down-Regulation · Fas Ligand Protein · Humans · Ligands · Longitudinal Studies · Membrane Glycoproteins · Middle Aged · Multiple Sclerosis, Chronic Progressive · Multiple Sclerosis, Relapsing-Remitting · Receptors, CCR5 · Receptors, Chemokine · RNA, Messenger · Up-Regulation
[Abstract]

7 Functions of CD40 and its ligand, gp39 (CD40L)
article 1996    
Author: Laman, J.D. · Claassen, E. · Noelle, R.J.
Keywords: Biology · Antibody · Autoimmunity · CD40 · CD40 Ligand · Cognate T and B cell interaction · Gp39 · Isotype switching · Lymphocyte activation · Signal transduction · Tolerance · Cd40 antigen · Autoimmunity · B lymphocyte activation · Cell proliferation · Drug receptor binding · gGene switching · Germinal center · Human · Human cell · Immunological tolerance · Immunotherapy · Ligand binding · Lymphocyte activation · Review · Signal transduction · T lymphocyte activation · Animals · Antigens, CD40 · Antigens, Differentiation, T-Lymphocyte · Apoptosis · Autoimmune Diseases · CD40 Ligand · Gene Expression Regulation · Humans · Ligands · Lymphocytes · Membrane Glycoproteins · Mice · Mice, Knockout · Signal Transduction · Structure-Activity Relationship · Tumor Necrosis Factor-alpha
[Abstract]

8 Involvement of aspartic and glutamic residues in kringle-2 of tissue-type plasminogen activator in lysine binding, fibrin binding and stimulation of activity as revealed by chemical modification and oligonucleotide-directed mutagenesis
article 1990    
Author: Weening-Verhoeff, E.J.D. · Quax, P.H.A. · Leeuwen, R.T.J. van · Rehberg, E.F. · Marotti, K.R. · Verheijen, J.H.
Keywords: Health · Chemical modification · Ligand binding · Site directed mutagenesis · Amino Acid Sequence · Aspartic Acid · Base Sequence · Ethyldimethylaminopropyl Carbodiimide · Fibrin · Glutamates · Kinetics · Lysine · Molecular Sequence Data · Mutagenesis, Site-Directed · Mutation · Peptide Fragments · Plasminogen · Protein Engineering · Tissue Plasminogen Activator

9 Lysine-based cluster mannosides that inhibit ligand binding to the human mannose receptor at nanomolar concentration
article 1996    
Author: Biessen, E.A.L. · Noorman, F. · Teijlingen, M.E. van · Kuiper, J. · Barrett-Bergshoeff, M.M. · Bijsterbosch, M.K. · Rijken, D.G. · Berkel, T.J.G. van
Keywords: Biology · Mannose receptor · Mannoside · Binding site · Ligand binding · Receptor affinity · receptor binding · Binding, Competitive · Biotin · Chromatography, Thin Layer · Humans · Kinetics · Lectins · Lectins, C-Type · Lysine · Magnetic Resonance Spectroscopy · Mannose-Binding Lectins · Oligosaccharides · Receptors, Cell Surface · Ribonucleases · Tissue Plasminogen Activator
[PDF] [Abstract]

10 CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis
article 1996    
Author: Gerritse, K. · Laman, J.D. · Noelle, R.J. · Aruffo, A. · Ledbetter, J.A. · Boersma, W.J.A. · Claassen, E.
Keywords: Health · Animals · Antibodies, Monoclonal · Antigens, CD40 · B-Lymphocytes · CD4-Positive T-Lymphocytes · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Female · Humans · Immunohistochemistry · Immunotherapy · Membrane Glycoproteins · Mice · Mice, Inbred Strains · Monocytes · Multiple Sclerosis · T-Lymphocytes, Helper-Inducer
[PDF] [Abstract]

11 The origin of speciation: Trace metal kinetics over natural water/sediment interfaces and the consequences for bioaccumulation
article 2009    
Author: Vink, J.P.M.
Keywords: Geosciences · Availability · Biotic ligand model, Water Framework Directive · Free ion activity · Risk assessment · Uptake · Bio availabilities · Biotic ligand model, Water Framework Directive · Chemical conditions · Chironomus riparius · Exposure concentrations · Free ion activity · Free ions · Free metals · Geochemical conditions · Pore waters · Redox conditions · Sediment pore waters · Trace metals · Uptake · Bioaccumulation · Biochemistry · Cadmium compounds · Chemical speciation · Dissolution · Heavy metals · Ion exchange · Ions · Lead · Metal ions · Metals · Risk assessment · Risk management · Sedimentation · Sedimentology · Surface waters · Trace analysis · Trace elements · Water · Zinc · Heavy water
[Abstract]

12 Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF)
article 2006    
Author: Burger-Kentischer, A. · Göbel, H. · Kleemann, R. · Zernecke, A. · Bucala, R. · Leng, L. · Finkelmeier, D. · Geiger, G. · Schaefer, H.E. · Schober, A. · Weber, C. · Brunner, H. · Rütten, H. · Ihling, C. · Bernhagen, J.
Keywords: Biology · Biomedical Research · ApoE-/- · Inflammation · MIF · Apontaneous atherosclerosis · apolipoprotein E · CD40 ligand · Fibrinogen · Gelatinase A · Immunoglobulin G · Intercellular adhesion molecule 1 · Interleukin 12 · Interleukin 6 · Macrophage migration inhibition factor · Monoclonal antibody · Neutralizing antibody · Stress activated protein kinase · Transcription factor · Tumor necrosis factor · Animal experiment · Animal model · Animal tissue · Atherosclerotic plaque · Controlled study · Foam cell · Heart valve · Macrophage · Mediator release · Mouse · Nonhuman · Protein expression · Animals · Antibodies, Monoclonal · Aorta, Thoracic · Aortitis · Apolipoproteins E · Atherosclerosis · CD40 Ligand · Disease Models, Animal · Follow-Up Studies · Gene Expression · Immunologic Factors · Intercellular Adhesion Molecule-1 · Interleukin-12 · Macrophage Migration-Inhibitory Factors · Matrix Metalloproteinase 2 · Mice · Mice, Inbred C57BL · Polymerase Chain Reaction · RNA · Tumor Necrosis Factor-alpha
[Abstract]

13 Chemogenomics approaches for receptor deorphanization and extensions of the chemogenomics concept to phenotypic space
article 2011    
Author: Horst, E. van der · Peironcely, J.E. · Westen, G.J.P. van · Hoven, O.O. van den · Galloway, W.R.J.D. · Spring, D.R. · Wegner, J.K. · Vlijmen, H.W.T. van · Ijzerman, A.P. · Overington, J.P. · Bender, A.
Keywords: Nutrition · Chemogenomics · Deorphanization · G-protein coupled receptors · GPCR · Mode of action analysis · Orphan receptors · Proteochemometrics · Target prediction · Virtual screening · G protein coupled receptor · ligand · Bayes theorem · chemical genetics · chemistry · chemogenomic · drug activity · drug industry · genomics · phenotype · proteochemometrics · review · Healthy for Life · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

14 Carbon monoxide and cyanide as intrinsic ligands to iron in the active site of [NiFe]-hydrogenases. NiFe(CN)2CO, biology's way to activate H2
article 1999    
Author: Pierik, A.J. · Roseboom, W. · Happe, R.P. · Bagley, K.A. · Albracht, S.P.J.
Keywords: Nutrition · Carbon monoxide · Cyanide · Hydrogenase · Chromatium vinosum · Complex formation · Enzyme active site · Enzyme subunit · Gene cluster · Hydrogen bond · Infrared spectroscopy · Iron metabolism · Ligand binding · Membrane binding · Nonhuman · Oxidation reduction reaction · Priority journal · Binding Sites · Carbon Isotopes · Chromatium · Cyanides · Electron Spin Resonance Spectroscopy · Hydrogen · Hydrogenase · Iron · Ligands · Nitrogen Isotopes · Spectroscopy, Fourier Transform Infrared · Allochromatium vinosum · Chromatium · Desulfovibrio gigas · Desulfovibrio vulgaris
[PDF] [Abstract]

15 Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis
article 1999    
Author: Howard, L.M. · Miga, A.J. · Vanderlugt, C.L. · Dal Canto, M.C. · Laman, J.D. · Noelle, R.J. · Miller, S.D.
Keywords: Biology · Animals · Antibodies · CD4-Positive T-Lymphocytes · CD40 Ligand · Cell Differentiation · Cell Division · Central Nervous System · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Female · Hypersensitivity, Delayed · Immunotherapy · Inflammation · Interferon Type II · Interleukins · Membrane Glycoproteins · Mice · Mice, Inbred Strains · Multiple Sclerosis · Myelin Proteolipid Protein · Myelin Sheath · Peptide Fragments · Th1 Cells
[PDF] [Abstract]

16 Localization in situ of costimulatory molecules and cytokines in B-cell non-Hodgkin's lymphoma
article 1998    
Author: Vyth-Dreese, F.A. · Boot, H. · Dellemijn, T.A.M. · Majoor, D.M. · Oomen, L.C.J.M. · Laman, J.D. · Meurs, M. van · Weger, R.A. de · Jong, D. de
Keywords: Health · Antigens, CD · Antigens, CD40 · Antigens, CD80 · Antigens, CD86 · Antigens, Differentiation · B-Lymphocytes · CD40 Ligand · Cytokines · Humans · Immunoconjugates · Immunohistochemistry · Ligands · Lymphoma, B-Cell · Lymphoma, Large-Cell, Diffuse · Lymphoma, Mucosa-Associated Lymphoid Tissue · Membrane Glycoproteins · Microscopy, Confocal · T-Lymphocytes
[Abstract]

17 Therapy with antibodies against CD40L (CD154) and CD44-variant isoforms reduces experimental autoimmune encephalomyelitis induced by a proteolipid protein peptide
article 1998    
Author: Laman, J.D. · Maassen, C.B.M. · Schellekens, M.M. · Visser, L. · Kap, M. · Jong, E. de · Puijenbroek, M. van · Stipdonk, M.J.B. van · Meurs, M. van · Schwärzler, C. · Günthert, U.
Keywords: Health · Accessory molecules · Blood-brain barrier · CD44 variant isoforms · Central nervous system (CNS) costimulation · Immunohistochemistry · Immunotherapy · Multiple sclerosis · Animals · Antibodies, Monoclonal · Antigens, CD40 · Antigens, CD44 · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Female · Immunization · Immunohistochemistry · Isoantigens · Membrane Glycoproteins · Mice · Myelin Proteolipid Protein · Peptide Fragments
[Abstract]

18 Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years
article 2006    
Author: Lopatinskaya, L. · Zwemmer, J. · Uitdehaag, B. · Lucas, K. · Polman, C. · Nagelkerken, L.
Keywords: Biomedical Research · Apoptosis · Chemokines · Cytokines · EDSS · Fas · MS · chemokine receptor CCR3 · chemokine receptor CCR5 · chemokine receptor CXCR3 · Fas antigen · FAS ligand · interleukin 10 · interleukin 12p35 · interleukin 12p40 · interleukin 4 · messenger RNA · OKT 4 · osteopontin · transforming growth factor beta1 · tumor necrosis factor alpha · adult · apoptosis · article · clinical article · controlled study · correlation analysis · disability · disease association · disease course · Expanded Disability Status Scale · female · human · human cell · male · multiple sclerosis · pathophysiology · peripheral blood mononuclear cell · post hoc analysis · prediction · quantitative analysis · real time polymerase chain reaction · relapse · remission · Adult · Antibodies, Monoclonal · Antigens, CD95 · Apoptosis · Biological Markers · Chemokines · Cytokines · Disability Evaluation · Fas Ligand Protein · Female · Follow-Up Studies · Humans · Male · Middle Aged · Multiple Sclerosis, Chronic Progressive · Multiple Sclerosis, Relapsing-Remitting · Predictive Value of Tests · RNA, Messenger
[Abstract]

19 RAGE activation induces invasiveness of RA fibroblast-like synoviocytes in vitro
article 2007    
Author: Steenvoorden, M.M.C. · Toes, R.E.M. · Ronday, H.K. · Huizinga, T.W.J. · Groot, J. de
Keywords: Biomedical Research · Fibroblast-like synoviocyte · HMGB-1 · Invasiveness · RAGE · Rheumatoid arthritis · advanced glycation end product · advanced glycation end product receptor · chemoattractant · glycosylated albumin · high mobility group B1 protein · ligand · matrigel · protein antibody · article · cell activation · cell function · cell invasion · controlled study · culture medium · fibroblast · human · human cell · in vitro study · joint prosthesis · priority journal · rheumatoid arthritis · serum · synovial fluid · synoviocyte · synovium · Antibodies, Anti-Idiotypic · Arthritis, Rheumatoid · Cell Movement · Cells, Cultured · Glycosylation End Products, Advanced · HMGB1 Protein · Humans · Receptors, Immunologic · Synovial Membrane
[Abstract]

20 Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol
article 2004    
Author: Espirito Santo, S.M.S. · Pires, N.M.M. · Boesten, L.S.M. · Gerritsen, G. · Bovenschen, N. · Dijk, K.W. van · Jukema, J.W. · Princen, H.M.G. · Bensadoun, A. · Li, W.P. · Herz, J. · Havekes, L.M. · Vlijmen, B.J.M. van
Keywords: Blood clotting factor 8 · Cholesterol · Ligand · Lipoprotein lipase · Liver protein · Low density lipoprotein receptor · Low density lipoprotein receptor related protein · Tissue plasminogen activator · Triacylglycerol · Von Willebrand factor · Animal experiment · Animal model · Animal tissue · Atherogenesis · Cholesterol blood level · Controlled study · Hyperlipoproteinemia type 3 · Liver function · Liver metabolism · Mouse · Nonhuman · Protein deficiency · Triacylglycerol blood level · Animals · Aorta · Apolipoproteins E · Arteriosclerosis · Blood Coagulation Factors · Cholesterol · LDL-Receptor Related Protein 1 · Lipids · Liver · Male · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 31 found. Next | Sort by date