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1 Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy
article 2018    
Author: Stee, M.F. van · Graaf, A.A. de · Groen, A.K.
Keywords: Biology · Atorvastatin · Combination therapy · Dyslipidemia · Glucose metabolism · Lipid metabolism · Metformin · Simvastatin · Type 2 diabetes
[PDF] [Abstract]

2 Systems biology approaches to the study of cardiovascular drugs
bookPart 2010    
Author: Nikolsky, Y. · Kleemann, R.
Keywords: Biology · Biological networks · Cardiovascular disease · Drugs · Inflammation · Lipid metabolism · Pathway analysis · Side effects · Signaling pathways · Systems biology
[Abstract]

3 Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: Studies using genetically engineered mouse models
article 2009    
Author: Voshol, P.J. · Rensen, P.C.N. · Dijk, K.W. van · Romijn, J.A. · Havekes, L.M.
Keywords: Biology · Biomedical Research · Animal model · Fatty acid · Fatty acid transporter · Lipid metabolism · Lipoprotein lipase · Metabolic syndrome · Obesity · Animalia
[Abstract]

4 Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion
article 2001    
Author: Mensenkamp, A.R. · Teusink, B. · Baller, J.F.W. · Wolters, H. · Havinga, R. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Fatty Liver · Lipid Metabolism · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · RNA, Messenger · Triglycerides
[Abstract]

5 Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice
article 2012    
Author: Wong, M.C. · Diepen, J.A. van · Hu, L. · Guigas, B. · Boer, H.C. de · Puijvelde, G.H. van · Kuiper, J. · Zonneveld, A.J. van · Shoelson, S.E. · Voshol, P.J. · Romijn, J.A. · Havekes, L.M. · Tamsma, J.T. · Rensen, P.C.N. · Hiemstra, P.S. · Berbée, J.F.P.
Keywords: Biology · Atherosclerosis · Hepatocyte · Inflammation · Lipid metabolism · Liver · Mouse models · NF-κB · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

6 Hepatocyte-specifi c IKK- β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice
article 2011    
Author: Diepen, J.A.V. · Wong, M.C. · Guigas, B. · Bos, J. · Stienstra, R. · Hodson, L. · Shoelson, S.E. · Jimmy F. P. Berbée · Rensen, P.C.N. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Health · I k B kinase β · Lipid metabolism · Liver · Nuclear factor kappa B · Very low density lipoprotein · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

7 Interactions between inflammation and lipid metabolism: Relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis
article 2013    
Author: Diepen, J.A. van · Berbée, J.F.P. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Atherosclerosis · Fatty acids · Inflammation · Inflammation-lowering drugs · Lipid metabolism · Lipoproteins · Mouse models · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

8 Alcohol
bookPart 2005    
Author: Hendriks, H.F. · Tol, A. van
Keywords: Health · Biomedical Research · C reactive protein · cholesterol · high density lipoprotein · homocysteine · lipoprotein · animal · blood · drinking behavior · human · hypertension · lipid metabolism · malnutrition · metabolism · nutritional value · physiology · review · Alcohol Drinking · Animals · C-Reactive Protein · Cholesterol · Homocysteine · Humans · Hypertension · Lipid Metabolism · Lipoproteins · Lipoproteins, HDL · Malnutrition · Nutritive Value
[Abstract]

9 Cafestol increases serum cholesterol levels in apolipoprotein E*3- leiden transgenic mice by suppression of bile acid synthesis
article 2000    
Author: Post, S.M. · Roos, B.de · Vermeulen, M. · Afman, L. · Jong, M.C. · Dahlmans, V.E.H. · Havekes, L.M. · Stellaard, F. · Katan, M.B. · Princen, H.M.G.
Keywords: Biology · Animals · Apolipoprotein E3 · Apolipoproteins E · Bile Acids and Salts · Cholesterol · Diet · Diterpenes · Feces · Female · Lipid Metabolism · Lipoproteins · Lipoproteins, IDL · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

10 Lipoxygenase-2 oxygenates storage lipids in embryos of germinating barley
article 1997    
Author: Holtman, W.L. · Vredenbregt-Heistek, J.C. · Schmitt, N.F. · Feussner, I.
Keywords: Barley · Lipoxygenase isoenzyme · Oxygenation · Storage lipid · Isoenzyme · Lipoxygenase · Enzyme activity · Enzyme specificity · Germination · High performance liquid chromatography · Lipid oxidation · Phytochemistry · Priority journal · Chromatography, High Pressure Liquid · Germination · Hordeum · Isoenzymes · Kinetics · Lipid Metabolism · Lipids · Lipoxygenase · Substrate Specificity · Hordeum vulgare subsp. vulgare
[Abstract]

11 Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity
article 2008    
Author: Pols, T.W.H. · Ottenhoff, R. · Vos, M. · Levels, J.H.M. · Quax, P.H.A. · Meijers, J.C.M. · Pannekoek, H. · Groen, A.K. · Vries, C.J.M. de
Keywords: Biology · Lipid metabolism · NR4A nuclear receptors · NR4A1 · Nur77 · SREBP1c · Sterol regulatory element binding protein-1 · ABC transporter · ABC transporter G5 · ABC transporter G8 · acyl coenzyme A desaturase · acyl coenzyme A desaturase 1 · adenovirus vector · fatty acid synthase · glycerol 3 phosphate acyltransferase · low density lipoprotein receptor · nuclear receptor Nur77 · sterol regulatory element binding protein 1c · triacylglycerol · animal experiment · animal tissue · article · controlled study · enzyme activity · enzyme repression · gene expression · genetic analysis · lipid blood level · lipid liver level · lipid metabolism · male · mouse · nonhuman · nucleotide sequence · priority journal · protein expression · protein function · Adenoviridae · Animals · DNA-Binding Proteins · Gene Expression Regulation · Lipid Metabolism · Liver · Male · Mice · Mice, Inbred C57BL · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · Sterol Regulatory Element Binding Protein 1 · Transcription Factors · Triglycerides · Mus
[Abstract]

12 Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor γ function (P465L PPARγ) in mice
article 2006    
Author: Gray, S.L. · Dalla Nora, E. · Grosse, J. · Manieri, M. · Stoeger, T. · Medina-Gomez, G. · Burling, K. · Wattler, S. · Russ, A. · Yeo, G.S.H. · Chatterjee, V.K. · O'Rahilly, S. · Voshol, P.J. · Cinti, S. · Vidal-Puig, A.
Keywords: Biology · Peroxisome proliferator activated receptor gamma · Adipose tissue · Animal cell · Animal experiment · Animal model · Animal tissue · Carbohydrate metabolism · Controlled study · Energy balance · Female · Gene expression · gene mutation · Homozygosity · Hyperphagia · Insulin resistance · Insulin sensitivity · Lipid metabolism · Lipid storage · Lipogenesis · Male · Metabolic disorder · Nonhuman · Obesity · Point mutation · Protein deficiency · Protein function · Tissue distribution · Tissue expansion · Blood · Genetics · Glucose blood level · Homozygote · Lethal gene · Metabolism · Mouse mutant · Pathology · Physiology · Adipose Tissue · Animals · Blood Glucose · Gene Expression Profiling · Genes, Lethal · Homozygote · Insulin · Insulin Resistance · Leptin · Lipid Metabolism · Mice · Mice, Obese · PPAR gamma
[Abstract]

13 Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice
article 2006    
Author: Boer, M.A.M. den · Voshol, P.J. · Schröder-van Der Elst, J.P. · Korsheninnikova, E. · Ouwens, D.M. · Kuipers, F. · Havekes, L.M. · Romijn, J.A.
Keywords: Biology · Biomedical Research · Amyloid A protein · fibrinogen · interleukin 10 · protein kinase B · Animal experiment · Calorimetry · Cholesterol blood level · Controlled study · Experimental model · Fatty liver · Feeding · Glucose blood level · Hlucose metabolism · High performance liquid chromatography · Hyperinsulinemia · Insulin sensitivity · Lipid diet · Lipid metabolism · Mouse · Nonhuman · Phosphorylation · Steatosis · Triacylglycerol blood level · Adipose Tissue · Animals · Blood Glucose · Chromatography, Thin Layer · Diet · Dietary Fats · Energy Metabolism · Fibrinogen · Genotype · Glucose · Glucose Clamp Technique · Insulin Resistance · Interleukin-10 · Lipid Metabolism · Lipids · Liver Diseases · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Phenotype · Serum Amyloid A Protein
[Abstract]

14 Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance
article 2004    
Author: Muurling, M. · Hoek, A.M. van den · Mensink, R.P. · Pijl, H. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Free fatty acid metabolism · Hepatic fat accumulation · Lipid metabolism · Peroxisome proliferator-activated receptor-γ · Rosiglitazone · Diacylglycerol · Glucose · Ketone body · Peroxisome proliferator activated receptor gamma · Rosiglitazone · Triacylglycerol · Adipose tissue · Animal experiment · Animal model · Animal tissue · APOC1 gene · Cholesterol blood level · Controlled study · Fatty acid metabolism · Gene · Gene overexpression · Gluconeogenesis · Glucose blood level · Glucose transport · Hyperglycemia · Hyperinsulinemia · Hyperlipidemia · Insulin blood level · Insulin resistance · Lipid metabolism · Lipid storage · Mouse · Nonhuman · Obesity · Transgenic mouse · Triacylglycerol blood level · Weight reduction · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Body Weight · Fatty Acids · Fatty Liver · Gene Expression · Humans · Hyperglycemia · Hyperinsulinism · Hyperlipidemias · Insulin · Insulin Resistance · Mice · Mice, Transgenic
[PDF] [Abstract]

15 The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis
article 2004    
Author: Goudriaan, J.R. · Espirito Santo, S.M.S. · Voshol, P.J. · Teusink, B. · Dijk, K.W. van · Vlijmen, B.J.M. van · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Adipose tissue · Free fatty acids · Lipoprotein lipase · Postprandial lipid metabolism · Transgenic mice · Very low density lipoprotein-like emulsion · Albumin · Carbon 14 · Chylomicron · Fatty acid · Lipoprotein lipase · Triacylglycerol · Very low density lipoprotein · Very low density lipoprotein receptor · Animal experiment · Animal tissue · Bolus injection · Continuous infusion · Controlled study · Diet restriction · Emulsion · Enzyme activity · Fatty acid transport · Female · Half life time · Lipid blood level · Lipid hydrolysis · Lipid metabolism · Lipolysis · Mouse · Nonhuman · Plasma clearance · Postprandial state · Protein expression · Transgenic mouse · Adipose Tissue · Albumins · Animals · Chylomicrons · Fatty Acids, Nonesterified · Mice · Receptors, LDL · Triglycerides
[PDF] [Abstract]

16 CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance
article 2005    
Author: Goudriaan, J.R. · oer, M.A.M. den · Rensen, P.C.N. · Febbraio, M. · Kuipers, F. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Fatty acid transport · Free fatty acids · Postprandial lipid metabolism · Transgenic mice · Triglyceride hydrolysis · CD36 antigen · Glycerol · Heparin · Triacylglycerol · Very low density lipoprotein · Animal experiment · Animal tissue · Body fat · CD36 deficiency · Controlled study · Enzyme inhibition · Enzyme metabolism · Half life time · In vitro study · Isotope labeling · Lipid metabolism · Mouse · Nonhuman · Protein deficiency · Protein function · Protein hydrolysis · Transgenic mouse · Tiacylglycerol blood level · Wild type · Animals · Antigens, CD36 · Eating · Fatty Acids, Nonesterified · Female · Intestinal Absorption · Lipoprotein Lipase · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Inbred C57BL · Triglycerides
[PDF] [Abstract]

17 An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: A nutrigenomics approach
article 2010    
Author: Bakker, G.C.M. · Erk, M.J. van · Pellis, L. · Wopereis, S. · Rubingh, C.M. · Cnubben, N.H.P. · Kooistra, T. · Ommen, B. van · Hendriks, H.F.J.
Keywords: Biology · Physiological Sciences · adiponectin · antiinflammatory agent · antioxidant · C reactive protein · adipose tissue · adult · article · blood · clinical trial · controlled clinical trial · controlled study · crossover procedure · diet · diet therapy · double blind procedure · drug effect · female · human · inflammation · lipid metabolism · liver · male · metabolic disorder · metabolism · methodology · middle aged · mononuclear cell · nutrigenomics · obesity · oxidative stress · pathophysiology · randomized controlled trial · vascular endothelium · Adiponectin · Adipose Tissue · Adult · Anti-Inflammatory Agents · Antioxidants · C-Reactive Protein · Cross-Over Studies · Diet · Double-Blind Method · Endothelium, Vascular · Female · Humans · Inflammation · Leukocytes, Mononuclear · Lipid Metabolism · Liver · Male · Metabolic Diseases · Middle Aged · Nutrigenomics · Overweight · Oxidative Stress · Young Adult
[Abstract]

18 Salsalate activates brown adipose tissue in mice
article 2015    
Author: Dam, A.D. van · Nahon, K.J. · Kooijman, S. · Berg, S.M. van den · Kanhai, A.A. · Kikuchi, T. · Heemskerk, M.M. · Harmelen,V. van · Lombès, M. · Hoek,A.M. van den · Winther, M.P. de · Lutgens, E. · Guigas, B. · Rensen, P.C. · Boon, M.R.
Keywords: Biology · Salicylic acid derivative · Salsalate · Administration and dosage · Adverse effects · Brown adipose tissue · Drug administration · Drug effects · Fat intake · Metabolism · Mouse · Physiology · Transgenic mouse · Adipose Tissue, Brown · Animals · Dietary Fats · Drug Administration Schedule · Glucose · Lipid Metabolism · Male · Mice · Mice, Transgenic · Obesity · Salicylates · Weight Gain · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

19 Adenovirus mediated overexpression of human phospholipid transfer protein alters plasma HDL levels in mice
article 1998    
Author: Ehnholm, S. · Dijk, K.W. van · Hof, B. van · Zee, A.D. van · Olkkonen, V.M. · Jauhiainen, M. · Hofker, M. · Havekes, L. · Ehnholm, C.
Keywords: Biology · Apolipoprotein A-I · HDL conversion · HDL metabolism · Lipid metabolism · Phospholipid transfer protein · Recombinant adenovirus · Adenoviridae · Animals · Apolipoprotein A-I · Carrier Proteins · Cholesterol · Cholesterol Esters · Female · Genetic Vectors · Humans · Lipoproteins · Lipoproteins, HDL · Liver · Membrane Proteins · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phospholipid Transfer Proteins · Phospholipids · Recombinant Proteins · Triglycerides
[PDF] [Abstract]

20 Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein
article 2007    
Author: Gautier, T. · Tietge, U.J.F. · Boverhof, R. · Perton, F.G. · Le Guern, N. · Masson, D. · Rensen, P.C.N. · Havekes, L.M. · Lagrost, L. · Kuipers, F.
Keywords: Biology · Biomedical Research · Bile · Cholesterol · Triglycerides · bile acid · cholesterol · cholesterol ester transfer protein · high density lipoprotein · triacylglycerol · very low density lipoprotein · animal model · bile secretion · cholesterol blood level · controlled study · insulin metabolism · lipid metabolism · lipid storage · mouse · nonhuman · stress · Animals · Apolipoprotein C-I · Cholesterol Ester Transfer Proteins · Gallbladder · Lipids · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Polymerase Chain Reaction · RNA
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 65 found. Next | Sort by date