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Showing 1 to 18 of 18 found. | Sort by date

1 Two-locus linkage analysis applied to putative quantitative trait loci for lipoprotein(a) levels
article 2003    
Author: Beekman, M. · Heijmans, B.T. · Martin, N.G. · Whitfield, J.B. · Pedersen, N.L. · Faire, U. de · Snieder, H. · Lakenberg, N. · Knijff, P. de · Frants, R.R. · Ommen, G.J.B. van · Kluft, C. · Vogler, G.P. · Slagboom, P.E. · Boomsma, D.I.
Keywords: Health · Lipoprotein A · Adult · Cardiovascular disease · Chromosome 1 · Chromosome 6 · Dizygotic twins · Genetic linkage · Health status · Heritability · Lipoprotein blood level · Major clinical study · Monozygotic twins · Adolescent · Chromosomes, Human, Pair 1 · Chromosomes, Human, Pair 6 · Humans · Linkage (Genetics) · Lipoproteins · Quantitative Trait Loci · Twins · Twins, Dizygotic · Twins, Monozygotic
[Abstract]

2 Immunological discrimination between the human apolipoprotein E2(Arg158→Cys) and E3 isoforms
article 1992    
Author: Gerritse, K. · Knijff, P. de · Ierssel, G.V. · Havekes, L.M. · Frants, R.R. · Schellekens, M.M. · Zegers, N.D. · Claassen, E. · Boersma, W.J.A.
Keywords: Synthetic peptides · Type III hyperlipoproteinemia · Apolipoprotein e2 · Apolipoprotein e3 · Lipoprotein receptor · Monoclonal antibody · Amino acid sequence · Antigenicity · Binding affinity · Immunological tolerance · Lipid metabolism · Lipoprotein blood level · Nonhuman · Sequence homology · Amino Acid Sequence · Animal · Antibodies, Monoclonal · Antibody Specificity · Apolipoproteins E · Arginine · Cysteine · Enzyme-Linked Immunosorbent Assay · Epitopes · Female · Human · Immunoblotting · Isoelectric Focusing · Mice · Mice, Inbred BALB C · Molecular Sequence Data · Phenotype · Sequence Alignment
[PDF] [Abstract]

3 ApoE plasma levels and risk of cardiovascular mortality in old age
article 2006    
Author: Mooijaart, S.P. · Berbée, J.F.P. · Heemst, D. van · Havekes, L.M. · Craen, A.J.M. de · Slagboom, P.E. · Rensen, P.C.N. · Westendorp, R.G.J.
Keywords: Health · Biomedical Research · Apoenzyme · C reactive protein · Lipid · Low density lipoprotein cholesterol · Triacylglycerol · Aged · Cardiovascular disease · Cardiovascular risk · Cholesterol blood level · Controlled study · Enzyme blood level · Female · Follow up · Genotype · Human · Lipid blood level · Lipoprotein blood level · Lajor clinical study · Male · Mortality · Population based case control study · Protein blood level · Senescence · Triacylglycerol blood level
[PDF] [Abstract]

4 The expression of type III hyperlipoproteinemia: Involvement of lipolysis genes
article 2009    
Author: Henneman, P. · Sman-de Beer, F. van der · Moghaddam, P.H. · Huijts, P. · Stalenhoef, A.F.H. · Kastelein, J.J.P. · Duijn, C.M. van · Havekes, L.M. · Frants, R.R. · Dijk, K.W. van · Smelt, A.H.M.
Keywords: Biology · Biomedical Research · adenine · apolipoprotein A5 · apolipoprotein C3 · apolipoprotein E2 · cytosine · guanine · lipoprotein lipase · liver triacylglycerol lipase · thymine · adult · aged · article · controlled study · disease severity · female · gene expression · gene frequency · gene function · gene linkage disequilibrium · genetic association · genetic polymorphism · genetic variability · human · human cell · hyperlipidemia · hyperlipoproteinemia type 3 · hypertriglyceridemia · lipolysis · lipoprotein blood level · major clinical study · male · mutational analysis · Netherlands · priority journal
[Abstract]

5 Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet
article 2011    
Author: Diepen, J.A. van · Vroegrijk, I.O.C.M. · Berbée, J.F.P. · Shoelson, S.E. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N. · Voshol, P.J.
Keywords: Biology · Inflammation · Lipid metabolism · Very low-density lipoprotein · acetylsalicylic acid · apolipoprotein C1 · immunoglobulin enhancer binding protein · transcription factor RelA · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · controlled study · drug mechanism · drug targeting · enzyme inhibition · gene expression · hypertriglyceridemia · in vivo study · lipid diet · lipogenesis · lipoprotein blood level · male · metabolic syndrome X · mouse · nonhuman · priority journal · protein expression · risk factor · triacylglycerol blood level · aspirin · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

6 Effects of fish oil on oxidation resistance of VLDL in hypertriglyceridemic patients
article 1996    
Author: Hau, M.-F. · Smelt, A.H.M. · Bindels, A.J.G.H. · Sijbrands, E.J.G. · Laarse, A. van der · Onkenhout, W. · Duyvenvoorde, W. van · Princen, H.M.G.
Keywords: Biology · fish oil · hypertriglyceridemia · LDL oxidation · omega-3 fatty acids · VLDL oxidation · alpha tocopherol · cholesterol · fish oil · high density lipoprotein cholesterol · low density lipoprotein cholesterol · omega 3 fatty acid · polyunsaturated fatty acid · triacylglycerol · very low density lipoprotein cholesterol · adult · article · clinical article · diet supplementation · fat intake · fatty acid blood level · human · hyperlipidemia · hypertriglyceridemia · lipid blood level · lipid oxidation · lipoprotein blood level · male · oral drug administration · priority journal · Adult · Diet · Fish Oils · Humans · Hypertriglyceridemia · Lipid Peroxidation · Lipoproteins, VLDL · Male · Middle Aged
[Abstract]

7 Seasonal variation in low density lipoprotein oxidation and antioxidant status
article 1997    
Author: Vijver, L.P.L. van de · Duyvenvoorde, W. van · Buytenhek, R. · Laarse, A. van der · Kardinaal, A.F.M. · Berg, H. van den · Princen, H.M.G.
Keywords: Antioxidants · LDL oxidation · Particle size · Within-subject seasonal variation · alpha tocopherol · antioxidant · beta carotene · cholesterol · copper ion · low density lipoprotein · xanthophyll · antioxidant activity · article · atherogenesis · cholesterol blood level · clinical article · controlled study · lipid blood level · lipid composition · lipid peroxidation · lipoprotein blood level · normal human · particle size · seasonal variation · vitamin blood level · Adult · Antioxidants · Cholesterol · Cholesterol, LDL · Fatty Acids · Female · Humans · Lipids · Lipoproteins, LDL · Lutein · Male · Middle Aged · Oxidation-Reduction · Seasons · Vitamin E

8 Apolipoprotein CI deficiency markedly augments plasma lipoprotein changes mediated by human cholesteryl ester transfer protein (CETP) in CETP transgenic/apoCI-knocked out mice
article 2002    
Author: Gautier, T. · Masson, D. · Jong, M.C. · Duverneuil, L. · Guern, N.L. · Deckert, V. · Barros, J.-P.P.de · Dumont, L. · Bataille, A. · Zak, Z. · Jiang, X.-C. · Tall, A.R. · Havekes, L.M. · Lagrost, L.
Keywords: Biology · Cholesterol · Chromatographic analysis · Esters · Proteins · Apolipoproteins · Biochemistry · High density lipoprotein · Very low density lipoprotein · Animal experiment · Concentration response · Controlled study · Gel permeation chromatography · Knockout mouse · Lipoprotein blood level · Mouse · Nonhuman · Protein deficiency · Protein expression · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Carrier Proteins · Cholesterol Ester Transfer Proteins · Glycoproteins · Humans · Kinetics · Lipoproteins · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Animalia · Mus musculus
[PDF] [Abstract]

9 Combined Association and Linkage Analysis Applied to the APOE Locus
article 2004    
Author: Beekman, M. · Posthuma, D. · Heijmans, B.T. · Lakenberg, N. · Suchiman, H.E.D. · Snieder, H. · Knijff, P. de · Frants, R.R. · Ommen, G.J.B. van · Kluft, C. · Vogler, G.P. · Slagboom, P.E. · Boomsma, D.I.
Keywords: ApoE level · Fine-mapping · Quantitative trait locus · Twin pairs · chromosome 19 · cohort analysis · gene locus · gene mapping · genetic association · genetic linkage · genetic polymorphism · genotype · linkage analysis · lipoprotein blood level · quantitative trait locus · short tandem repeat · twins · Adolescent · Adult · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoprotein E4 · Apolipoproteins E · Chromosomes, Human, Pair 19 · Cohort Studies · Female · Genotype · Humans · Linkage (Genetics) · Lod Score · Male · Netherlands · Polymorphism, Genetic · Quantitative Trait, Heritable · Genetta
[Abstract]

10 Plasma apolipoprotein CI protects against mortality from infection in old age
article 2008    
Author: Berbée, J.F.P. · Mooijaart, S.P. · Craen, A.J.M. de · Havekes, L.M. · Heemst, D. van · Rensen, P.C.N. · Westendorp, R.G.J.
Keywords: Biomedical Research · Apolipoprotein CI · High-density lipoprotein · Infection · Apolipoprotein C1 · C reactive protein · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Triacylglycerol · Aged · Cause of death · Controlled study · Correlation analysis · Follow up · Human experiment · Infection · Infection risk · lipid blood level · Lipoprotein blood level · Mortality · Population research · Protein blood level · Risk reduction · Blood · Metabolism · Proportional hazards model · Prospective study · Bacteria (microorganisms) · Mus · Rodentia · Aged, 80 and over · Apolipoproteins C · C-Reactive Protein · Cause of Death · Cholesterol, HDL · Cholesterol, LDL · Enzyme-Linked Immunosorbent Assay · Female · Humans · Infection · Male · Netherlands · Proportional Hazards Models · Prospective Studies · Triglycerides
[Abstract]

11 Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine
article 1996    
Author: Hasler-Rapacz, J. · Kempen, H.J. · Princen, H.M.G. · Kudchodkar, B.J. · Lacko, A. · Rapacz, J.
Keywords: Biology · animal model · apolipoproteins · familial hypercholesterolemia · simvastatin · swine · apolipoprotein a · apolipoprotein b · apolipoprotein c3 · apolipoprotein e · high density lipoprotein cholesterol · hydroxymethylglutaryl coenzyme a reductase · lathosterol · lipid · low density lipoprotein cholesterol · phosphatidylcholine sterol acyltransferase · simvastatin · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · animal tissue · article · calculation · cholesterol blood level · dose response · enzyme activity · hypercholesterolemia · hyperlipidemia · lipid analysis · lipid blood level · lipoprotein blood level · nonhuman · priority journal · statistical analysis · swine · Animals · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoproteins · Apolipoproteins B · Apolipoproteins C · Apolipoproteins E · Cholesterol · Cholesterol, HDL · Cholesterol, LDL · Enzyme Inhibitors · Female · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipoproteinemia Type II · Lipids · Male · Swine · Swine Diseases · Triglycerides
[Abstract]

12 ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglycerides (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
article 2004    
Author: Schaap, F.G. · Rensen, P.C.N. · Voshol, P.J. · Vrins, C. · Vliet, H.N. van der · Chamuleau, R.A.F.M. · Havekes, L.M. · Groen, A.K. · Dijk, K.W. van
Keywords: Biology · Biomedical Research · Data reduction · Enzymes · Gene transfer · Metabolism · Reaction kinetics · Lipolytic conversion · Lipoproteins · Biochemistry · Apolipoprotein A · Apolipoprotein a5 · Triacylglycerol · Unclassified drug · Very low density lipoprotein · Animal experiment · APO5 gene · Gene · Gene transfer · Hydrolysis · Hyperlipidemia · Hypertriglyceridemia · Lipid blood level · Lipid metabolism · Lipoprotein blood level · Mouse · Nonhuman · Triacylglycerol blood level · Adenoviridae · Adipose Tissue · Animals · Apolipoproteins · Dose-Response Relationship, Drug · Gene Transfer Techniques · Hydrolysis · Kinetics · Lipids · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Inbred C57BL · Muscle, Skeletal · Postprandial Period · Rats · Recombinant Proteins · Time Factors · Triglycerides · Animalia · Murinae
[PDF] [Abstract]

13 Job strain and risk indicators for cardiovascular disease in young female nurses
article 2000    
Author: Riese, H. · Houtman, I.L.D. · Doornen, L.J.P. · Geus, E.J.C. de
Keywords: Workplace · Decision latitude · Fasting insulin · Insulin resistance syndrome · Job demands · Lipids · Antigen · Cholesterol · Fibrinogen · High density lipoprotein cholesterol · Insulin · Oral contraceptive agent · Plasminogen activator inhibitor 1 · Tissue plasminogen activator · Triacylglycerol · Adult · Age · Blood pressure · Body mass · Cardiovascular disease · Cardiovascular risk · Cholesterol blood level · Decision making · Fibrinogen blood level · Insulin blood level · Job performance · Lipoprotein blood level · Oral contraception · Questionnaire · Risk factor · Social support · Stress · Triacylglycerol blood level · Work capacity · Work schedule · Workload · Body Mass Index · Cardiovascular Diseases · Female · Fibrinogen · Humans · Job Satisfaction · Lipoproteins · Middle Aged · Nurses · Werkdruk · Verpleegkundigen · Hart en vaatziekten · Vrouwen
[Abstract]

14 Safety of long-term consumption of plant sterol esters-enriched spread
article 2003    
Author: Hendriks, H.F.J. · Brink, E.J. · Meijer, G.W. · Princen, H.M.G. · Ntanios, F.Y.
Keywords: Health Nutrition · Physiological Sciences · Cholesterol lowering · Coronary heart disease · Efficacy · Long-term study · Plant sterol esters · Safety · Spread · Alpha carotene · Beta carotene · Campesterol · Carotenoid · Cholesterol · Estradiol · Fatty acid ester · Follitropin · Low density lipoprotein cholesterol · Luteinizing hormone · Phytosterol · Progesterone · Sitosterol · Testosterone · Vitamin · Adult · Blood analysis · Cholesterol blood level · Clinical trial · Controlled clinical trial · Controlled study · Dietary intake · Double blind procedure · Eating habit · Erythrocyte deformability · Estradiol blood level · Female · Follitropin blood level · Human · Human experiment · Lifestyle · Lipid solubility · Lipoprotein blood level · Luteinizing hormone blood level · Male · Normal human · Nutrient concentration · Nutritional status · Outcomes research · Parallel design · Progesterone blood level · Randomized controlled trial · Testosterone blood level · Adult · Beta Carotene · Carotenoids · Cholesterol · Cholesterol, LDL · Diet · Dietary Fats · Double-Blind Method · Esters · Female · Humans · Male · Margarine · Middle Aged · Phytosterols · Placebos · Sitosterols
[Abstract]

15 The Netherlands twin register biobank: A resource for genetic epidemiological studies
article 2010    
Author: Willemsen, G. · Geus, E.J.C. de · Bartels, M. · Beijsterveldt, C.E.M.T. van · Brooks, A.I. · Estourgie-van Burk, G.F. · Fugman, D.A. · Hoekstra, C. · Hottenga, J.-J. · Kluft, K. · Meijer, P. · Montgomery, G.W. · Rizzu, P. · Sondervan, D. · Smit, A.B. · Spijker, S. · Suchiman, H.E.D. · Tischfield, J.A. · Lehner, T. · Slagboom, P.E. · Boomsma, D.I.
Keywords: Biology · Biomedical Research · DNA · GWAS · Mental health · Physical health · RNA · alanine aminotransferase · aspartate aminotransferase · C reactive protein · cholesterol · creatinine · fibrinogen · gamma glutamyltransferase · glucose · hemoglobin · hemoglobin A1c · high density lipoprotein cholesterol · insulin · low density lipoprotein cholesterol · triacylglycerol · adult · alanine aminotransferase blood level · article · aspartate aminotransferase blood level · basophil · blood sampling · body composition · cell line · cholesterol blood level · creatinine blood level · DNA isolation · eosinophil count · erythrocyte count · female · fibrinogen blood level · gamma glutamyl transferase blood level · gene expression · genetic epidemiology · genotype · glucose blood level · glucose metabolism · hematocrit · hemoglobin blood level · heredity · human · insulin blood level · leukocyte count · lifestyle · lipoprotein blood level · lymphocyte count · male · mean corpuscular hemoglobin · mean corpuscular volume · menstrual cycle · mental health · monocyte · Netherlands · Netherlands twin register biobank · neutrophil count · phenotype · priority journal · professional practice · register · single nucleotide polymorphism · thrombocyte count · thrombocyte volume · triacylglycerol blood level · urinalysis
[Abstract]

16 Atorvastatin increases HDL cholesterol by reducing CETP expression in cholesterol-fed APOE*3-Leiden.CETP mice
article 2008    
Author: Haan, W. de · Hoogt, C.C. van der · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Princen, H.M.G. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · CETP · High-density lipoprotein · HMGCoA reductase · Statin · Transgenic mice · ABC transporter A1 · apolipoprotein A1 · apolipoprotein E3 · atorvastatin · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · messenger RNA · phospholipid transfer protein · scavenger receptor BI · very low density lipoprotein · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · cholesterol diet · controlled study · drug effect · gene expression · hypercholesterolemia · lipoprotein blood level · lipoprotein metabolism · male · mouse · nonhuman · priority journal · protein expression · transgenic mouse · Animals · Apolipoprotein E3 · Cholesterol Ester Transfer Proteins · Cholesterol, Dietary · Cholesterol, HDL · Cholesterol, VLDL · Dose-Response Relationship, Drug · Female · Gene Expression · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypercholesterolemia · Liver · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Pyrroles · RNA, Messenger
[Abstract]

17 Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice
article 2008    
Author: Hoorn, J.W.A. van der · Haan, W. de · Berbée, J.P.P. · Havekes, L.M. · Jukema, J.W. · Rensen, P.C. · Princen, H.M.G.
Keywords: APOE*3Leiden.CETP transgenic mice · CETP · HDL-cholesterol · Hyperlipidemia · Niacin · cholesterol · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · low density lipoprotein cholesterol · nicotinic acid · triacylglycerol · antilipemic agent · CETP protein, human · messenger RNA · animal experiment · animal model · animal tissue · blood level · cholesterol blood level · controlled study · dose response · drug dose comparison · drug mechanism · female · gene activity · gene expression regulation · hypercholesterolemia · hypertriglyceridemia · kidney · lipid transport · lipoprotein blood level · liver · mouse · mouse strain · nonhuman · particle size · plasma clearance · priority journal · protein blood level · protein function · protein transport · transgenic mouse · triacylglycerol blood level · atherosclerosis · bile · blood · chemistry · disease model · drug effect · fat intake · feces · genetics · metabolism · time · upregulation · Animals · Antilipemic Agents · Apolipoprotein A-I · Apolipoprotein E3 · Atherosclerosis · Bile · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Dietary Fats · Disease Models, Animal · Dose-Response Relationship, Drug · Feces · Female · Humans · Liver · Mice · Mice, Transgenic · Niacin · RNA, Messenger · Time Factors · Triglycerides · Up-Regulation
[Abstract]

18 Apolipoprotein E*3-Leiden transgenic mice mode for hypolipidaemic drugs
article 1998    
Author: Vlijmen, B.J.M. van · Pearce, N.J. · Bergö, M. · Staels, B. · Yates, J.W. · Gribble, A.D. · Bond, B.C. · Hofker, M.H. · Havekes, L.M. · Groot, P.H.E.
Keywords: Pharmacology · ±(3R*,5S*)3-Carboxy-11-(2,4-dichlorophenyl)-3,5-dihydroxyundecanoic acid, 5-ring lactone · CAS 154566-12-8 · Gemfibrozil · Hypolipidaemic drugs, testing in transgenic mice · Lovastatin · SB 204990, hypolipidaemic effect · 3 carboxy 11 (2,4 dichlorophenyl) 3,5 dihydroxyundecanoic acid · Antilipemic agent · Apolipoprotein c3 · Apolipoprotein e3 · Cholesterol · Gemfibrozil · High density lipoprotein · Lipoprotein lipase · Low density lipoprotein · Messenger rna · Mevinolin · Sb 204990 · Triacylglycerol · Unclassified drug · Very low density lipoprotein · Anticoagulant agent · Apolipoprotein E · Apolipoprotein E3 · Heparin · Lactone · Lipid · Messenger RNA · SB 204990 · Animal model · Animal tissue · Atherosclerosis · Cholesterol blood level · Controlled study · Dose response · Drug effect · Enzyme activity · Gene expression · Hyperlipidemia · Lipoprotein blood level · Male · Mouse · Nonhuman · Oral drug administration · Transgenic mouse · Animal · Biosynthesis · Blood · C57BL mouse · Drug screening · Genetics · Liver · Metabolism · hysiology · Animals · Anticoagulants · Antilipemic Agents · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Drug Evaluation, Preclinical · Gemfibrozil · Heparin · Lactones · Lipids · Lipoprotein Lipase · Liver · Lovastatin · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · RNA, Messenger · Triglycerides
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date