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21 Low-density lipoproteins are degraded in HepG2 cells with low efficiency
article 1993    
Author: Lombardi, P. · Mulder, M. · Wit, E. de · Berkel, T.J.C. van · Frants, R.R. · Havekes, L.M.
Keywords: Low density lipoprotein · Low density lipoprotein receptor · Cell density · Cell fractionation · Comparative study · Density gradient centrifugation · Endosome · Hepatoma cell · Human cell · Internalization · Isotope labeling · Lipoprotein metabolism · Protein degradation · Receptor down regulation · Biological Transport · Cell Aggregation · Cell Line · Cells, Cultured · Down-Regulation · Fibroblasts · Human · Iodine Radioisotopes · Kinetics · Lipoproteins, LDL · Liver · Lysosomes · Receptors, LDL · Support, Non-U.S. Gov't
[Abstract]

22 Low density lipoprotein receptor internalizes low density and very low density lipoproteins that are bound to heparan sulfate proteoglycans via lipoprotein lipase
article 1993    
Author: Mulder, M. · Lombardi, P. · Jansen, H. · Berkel, T.J.C. van · Frants, R.R. · Havekes, L.M.
Keywords: Biology · Animal · Biological Transport · Carcinoma, Hepatocellular · Cattle · Female · Fibroblasts · Heparan Sulfate Proteoglycan · Heparin Lyase · Heparitin Sulfate · Human · Kinetics · Lipoprotein Lipase · Lipoproteins, LDL · Lipoproteins, VLDL · Liver Neoplasms · Milk · Models, Biological · Polysaccharide-Lyases · Protein Binding · Proteoglycans · Receptors, LDL · Support, Non-U.S. Gov't · Tumor Cells, Cultured
[PDF] [Abstract]

23 Inefficient degradation of triglyceride-rich lipoprotein by HepG2 cells is due to a retarded transport to the lysosomal compartment
article 1993    
Author: Lombardi, P. · Mulder, M. · Boom, H. van der · Frants, R.R. · Havekes, L.M.
Keywords: Cholesterol acyltransferase · Lipoprotein · Lipoprotein receptor · Low density lipoprotein · Triacylglycerol · Very low density lipoprotein · Cholesterol blood level · Density gradient centrifugation · Endosome · Enzyme activity · Homeostasis · Human cell · Lipid transport · Protein binding · Protein degradation · Biological Transport · Cell Compartmentation · Cell Line · Cholesterol · Endocytosis · Esterification · Human · Lipoprotein Lipase · Lipoproteins, LDL · Lipoproteins, VLDL · Lysosomes · Sterol O-Acyltransferase · Support, Non-U.S. Gov't · Triglycerides
[PDF] [Abstract]

24 Association between trans fatty acid intake and cardiovascular risk factors in Europe: The TRANSFAIR study
article 2000    
Author: Vijver, L.P.L. van de · Kardinaal, A.F.M. · Couet, C. · Aro, A. · Kafatos, A. · Steingrimsdottir, L. · Amorim Cruz, J.A. · Moreiras, O. · Becker, W. · Amelsvoort, J.M.M. van · Vidal-Jessel, S. · Salminen, I. · Moschandreas, J. · Sigfússon, N. · Martins, I. · Carbajal, A. · Ytterfors, A. · Poppel, G. van
Keywords: fatty acid · high density lipoprotein · low density lipoprotein · adult · aged · article · cardiovascular disease · cholesterol blood level · controlled study · disease association · Europe · fat intake · female · food intake · human · lipid blood level · lipid composition · major clinical study · male · risk factor · trans isomer · Adipose Tissue · Aged · Cardiovascular Diseases · Cholesterol · Cross-Sectional Studies · Diet Records · Dietary Fats · Energy Intake · Europe · Fatty Acids · Female · Humans · Isomerism · Linear Models · Lipids · Lipoproteins, HDL · Lipoproteins, LDL · Male · Middle Aged · Risk Factors
[Abstract]

25 Enhanced susceptibility of low-density lipoproteins to oxidation in coronary bypass patients with progression of atherosclerosis
article 1995    
Author: Rijke, Y.B. de · Verwey, H.F. · Vogelezang, C.J.M. · Velde, E.A. van der · Princen, H.M.G. · Laarse, A. van der · Bruschke, A.V.G. · Berkel, T.J.C. van
Keywords: Biology · apolipoprotein B · coronary artery bypass surgery · coronary atherosclerosis · lipid peroxidation · low-density lipoprotein · apolipoprotein a · apolipoprotein b · cholesterol · high density lipoprotein · low density lipoprotein · retinol · triacylglycerol · adult · aged · angiography · article · atherosclerosis · blood analysis · clinical article · controlled study · coronary artery bypass graft · human · human tissue · lipid analysis · lipid oxidation · male · priority journal · Apolipoproteins · Arteriosclerosis · Ascorbic Acid · Centrifugation, Density Gradient · Coronary Artery Bypass · Disease Progression · Follow-Up Studies · Humans · Lipoproteins, LDL · Male · Middle Aged · Oxidation-Reduction · Triglycerides · Vitamin E
[Abstract]

26 Oxidation of LDL and extent of peripheral atherosclerosis
article 1999    
Author: Vijver, L.P.L. van de · Kardinaal, A.F.M. · Duyvenvoorde, W. van · Kruijssen, D.A.C.M. · Grobbee, D.E. · Poppel, G. van · Princen, H.M.G.
Keywords: Biology · Ankle-arm index · LDL composition · LDL oxidation · Peripheral atherosclerosis · Resistance time · Acetylsalicylic acid · Antihypertensive agent · Copper · Coumarin derivative · High density lipoprotein cholesterol · Low density lipoprotein · Low density lipoprotein cholesterol · Triacylglycerol · Adult · Aged · Arm · Atherosclerosis · Cholesterol blood level · Diet · Disease severity · Drug use · Human · Leg · Aged · Aged, 80 and over · Anticoagulants · Antihypertensive Agents · Arteriosclerosis · Aspirin · Cholesterol, Dietary · Coumarins · Diet, Fat-Restricted · Humans · Lipid Peroxidation · Lipoproteins, LDL · Male · Middle Aged · Odds Ratio · Risk Factors
[Abstract]

27 Seasonal variation in low density lipoprotein oxidation and antioxidant status
article 1997    
Author: Vijver, L.P.L. van de · Duyvenvoorde, W. van · Buytenhek, R. · Laarse, A. van der · Kardinaal, A.F.M. · Berg, H. van den · Princen, H.M.G.
Keywords: Antioxidants · LDL oxidation · Particle size · Within-subject seasonal variation · alpha tocopherol · antioxidant · beta carotene · cholesterol · copper ion · low density lipoprotein · xanthophyll · antioxidant activity · article · atherogenesis · cholesterol blood level · clinical article · controlled study · lipid blood level · lipid composition · lipid peroxidation · lipoprotein blood level · normal human · particle size · seasonal variation · vitamin blood level · Adult · Antioxidants · Cholesterol · Cholesterol, LDL · Fatty Acids · Female · Humans · Lipids · Lipoproteins, LDL · Lutein · Male · Middle Aged · Oxidation-Reduction · Seasons · Vitamin E

28 Potential of 99mTc-LDLs labeled by two different methods for scintigraphic detection of experimental atherosclerosis in rabbits
article 1993    
Author: Atsma, D.E. · Feitsma, R.I.J. · Camps, J. · Hooft, F.M. van 't · Wall, E.E. van der · Nieuwenhuizen, W. · Pauwels, E.K.J.
Keywords: Biology · LDL · Rradiolabeling · Scintigraphy · Dithionite · Low density lipoprotein · Sodium borohydride · Stannous chloride · Technetium 99m · Borane derivative · Borohydride potassium · Diagnostic agent · Technetium complex · Technetium Tc 99m low density lipoprotein · Technetium Tc 99m low-density lipoprotein · Abdominal aorta · Animal experiment · Animal model · Animal tissue · Clearance · Controlled study · Intermethod comparison · Isotope labeling · Scintiscanning · Thoracic aorta · Animal · Aorta · Arteriosclerosis · Borohydrides · Dithionite · Lipoproteins, LDL · Male · Organotechnetium Compounds · Rabbits · Support, Non-U.S. Gov't · Tin
[Abstract]

29 Metabolomics (liver and blood profiling) in a mouse model in response to fasting: A study of hepatic steatosis
article 2007    
Author: Ginneken, V. van · Verhey, E. · Poelmann, R. · Ramakers, R. · Dijk, K.W. van · Ham, L. · Voshol, P. · Havekes, L. · Eck, M. van · Greef, J. van der
Keywords: Analytical research · Biomedical research · Hepatic steatosis · Lipids · Liver · Metabolomics · Starvation · Triacylglycerols · cholesterol · cholesterol ester · low density lipoprotein cholesterol · phosphatidylcholine · phospholipid derivative · triacylglycerol · animal experiment · animal model · animal tissue · article · blood examination · controlled study · diet restriction · fatty liver · high performance thin layer chromatography · lipid blood level · lipid storage · liver homogenate · male · mass spectrometry · metabolomics · mouse · nonhuman · priority journal · reversed phase liquid chromatography · starvation · Animals · Blood · Cholesterol Esters · Chromatography, High Pressure Liquid · Disease Models, Animal · Fatty Liver · Food Deprivation · Lipoproteins, LDL · Liver · Male · Mice · Mice, Inbred C57BL · Phosphatidylcholines · Phospholipids · Triglycerides · Mammalia
[Abstract]

30 Plasma annexin A5 level relates inversely to the severity of coronary stenosis
article 2007    
Author: Tits, L.J.H. van · Heerde, W.L. van · Vleuten, G.M. van der · Graaf, J. de · Grobbee, D.E. · Vijver, L.P.L. van de · Stalenhoef, A.F. · Princen, H.M.
Keywords: Biology · Biomedical Research · Angiography · Annexin A5 · Atherosclerosis · Cardiovascular diseases · Coronary disease · Coronary stenosis · Oxidized low-density lipoprotein · Oxidized phospholipids · biological marker · lipocortin 5 · oxidized low density lipoprotein · adult · aged · article · atherosclerosis · cardiovascular risk · controlled study · coronary artery obstruction · disease severity · female · human · lipid peroxidation · major clinical study · male · priority journal · protein blood level · risk assessment · risk factor · Aged · Aged, 80 and over · Annexin A5 · C-Reactive Protein · Carotid Arteries · Cohort Studies · Coronary Angiography · Coronary Stenosis · Humans · Lipoprotein(a) · Lipoproteins, LDL · Male · Middle Aged
[Abstract]

31 Macrophage-specific inhibition of NF-κB activation reduces foam-cell formation
article 2007    
Author: Ferreira, V. · Dijk, K.W. van · Groen, A.K. · Vos, R.M. · Kaa, J. van der · Gijbels, M.J.J. · Havekes, L.M. · Pannekoek, H.
Keywords: Biology · Biomedical Research · ABCA1 mediated cholesterol efflux · Foam cell formation · Macrophage specific inhibition of NF-κB, IκBα · ox-LDL-PPARγ-CD36 "feed-forward cycle" · I kappa B kinase alpha · immunoglobulin enhancer binding protein · article · cell differentiation · cell line · cell specificity · controlled study · cytoplasm · foam cell · gene expression · human · human cell · lipid oxidation · lipid transport · monocyte · mouse · nonhuman · peritoneum cell · priority journal · protein degradation · protein expression · transgenic mouse · Animals · Antigens, CD36 · ATP-Binding Cassette Transporters · Cell Line · DNA-Binding Proteins · Foam Cells · Humans · I-kappa B Proteins · Lipoproteins, LDL · Macrophages · Mice · Mice, Inbred C57BL · NF-kappa B · PPAR gamma · Receptors, Cytoplasmic and Nuclear · Scavenger Receptors, Class A
[Abstract]

32 Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages
article 1999    
Author: Winther, M.P.J. de · Dijk, K.W. van · Vlijmen, B.J.M. van · Gijbels, M.J.J. · Heus, J.J. · Wijers, E.R. · Bos, A.C. van den · Breuer, M. · Frants, R.R. · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Acetyl-low density lipoprotein · Macrophage scavenger receptor · Transgenics · Yeast artificial chromosome · acetyl low density lipoprotein · cholesterol ester · scavenger receptor · animal cell · animal experiment · article · atherogenesis · cell proliferation · controlled study · foam cell · gene overexpression · immunohistochemistry · mouse · nonhuman · peritoneum macrophage · priority journal · transgenic mouse · yeast artificial chromosome · Animals · Base Sequence · Cells, Cultured · Chromosomes, Artificial, Yeast · Disease Models, Animal · Foam Cells · Gene Expression · Humans · Kupffer Cells · Lipoproteins, LDL · Macrophages, Peritoneal · Mice · Mice, Transgenic · Molecular Sequence Data · Polymerase Chain Reaction · Receptors, Immunologic · Receptors, Scavenger · RNA, Messenger · Scavenger Receptors, Class A · Sensitivity and Specificity · Species Specificity · Tissue Distribution
[Abstract]

33 Increased response to cholesterol feeding in apolipoprotein C1-deficient mice
article 1995    
Author: Ree, J.H. van · Hofker, M.H. · Broek, J.A.A. van den · Deursen, J.M.A. van · Boom, H. van der · Frants, R.R. · Wieringa, B. · Havekes, L.M.
Keywords: Biology · apolipoprotein c1 · apolipoprotein e · very low density lipoprotein · animal cell · animal experiment · animal model · article · cholesterol blood level · cholesterol intake · controlled study · embryo · female · gene targeting · hep 2 cell · homozygosity · hypercholesterolemia · lipoprotein deficiency · lipoprotein metabolism · mouse · mutant · nonhuman · priority journal · stem cell · triacylglycerol blood level · Animal · Apolipoproteins C · Cholesterol · Cholesterol, Dietary · Gene Targeting · Heterozygote · Homozygote · Lipoproteins, HDL Cholesterol · Lipoproteins, LDL Cholesterol · Lipoproteins, VLDL Cholesterol · Mice · Mice, Inbred C57BL · Mice, Inbred CBA · Mice, Transgenic · Mutation · Receptors, LDL · Support, Non-U.S. Gov't · Triglycerides
[Abstract]

34 Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein
article 1998    
Author: Schalkwijk, C.G. · Vermeer, M.A. · Stehouwer, C.D.A. · Koppele, J. te · Princen, H.M.G. · Hinsbergh, V.W.M. van
Keywords: Biology · Advanced glycation end product · Diabetes · Low density lipoprotein · Methylglyoxal · Arginine · Cholesterol ester · Cytochrome c · Iodine 125 · Low density lipoprotein · Low density lipoprotein receptor · Lysine · Methylglyoxal · Monocyte chemotactic protein 1 · Oxidized low density lipoprotein · Superoxide · Vasculotropin · Controlled study · Fluorescence · Human · Human cell · Isotope labeling · Lipid metabolism · Macrophage · Plasma clearance · Priority journal · Receptor affinity · Animals · Cell Line · Chemistry, Physical · Cytochrome c Group · Electrochemistry · Endothelium, Vascular · Fibroblasts · Humans · Lipid Peroxidation · Lipid Peroxides · Lipoproteins, LDL · Macrophages · Malondialdehyde · Mice · Oxidation-Reduction · Pyruvaldehyde · Receptors, LDL · Superoxides · Thiobarbituric Acid Reactive Substances · Murinae
[Abstract]

35 Effect of 17β-estradiol on plasma lipids and LDL oxidation in postmenopausal women with type II diabetes mellitus
article 1997    
Author: Brussaard, H.E. · Leuven, J.A.G. · Kluft, C. · Krans, H.M.J. · Duyvenvoorde, W. van · Buytenhek, R. · Laarse, A. van der · Princen, H.M.G.
Keywords: Biology · 17β- estradiol · Antioxidant · LDL oxidation · Non-insulin-dependent diabetes mellitus · Plasma lipid · Apolipoprotein a1 · Apolipoprotein b · Estradiol · Hemoglobin a · High density lipoprotein cholesterol · Insulin · Low density lipoprotein · Sulfonylurea derivative · Triacylglycerol · Adult · Controlled clinical trial · Controlled study · Coronary risk · Double blind procedure · Hormonal regulation · Human cell · Human tissue · Lipoprotein metabolism · Metabolic regulation · Non insulin dependent diabetes mellitus · Oral drug administration · Oxidation · Randomized controlled trial · Treatment outcome · Aged · Diabetes Mellitus, Type 2 · Estradiol · Female · Humans · Lipids · Lipoproteins, LDL · Middle Aged · Oxidation-Reduction · Particle Size · Postmenopause
[Abstract]

Search results also available in MS Excel format.

Prev Showing 21 to 35 of 35 found. | Sort by date