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Showing 1 to 9 of 9 found. | Sort by date

1 Effect of variable versus fixed exposure levels on the toxicity of acetaldehyde in rats
article 1986    
Author: Appelman, L.M. · Woutersen, R.A. · Feron, V.J. · Hooftman, R.N. · Notten, W.R.F.
Keywords: Acetaldehyde · Animal experiment · Inhalation · Intoxication · Lung alveolus macrophage · Lung toxicity · Nonhuman · Nose mucosa · Olfactory epithelium · Olfactory system · Phagocytosis · Rat · Respiratory system · Acetaldehyde · Administration, Inhalation · Animal · Drug Administration Schedule · Lung · Male · Nasal Mucosa · Phagocytosis · Rats · Rats, Inbred Strains
[Abstract]

2 Use of physicochemical calculation of pKa and CLogP to predict phospholipidosis-inducing potential: A case study with structurally related piperazines
article 2004    
Author: Ploemen, J.P.H.T.M. · Kelder, J. · Hafmans, T. · Sandt, H. van de · Burgsteden, J.A. van · Salemink, P.J.M. · Esch, E. van
Keywords: Health Physiology · Physiological Sciences · Alveolar histiocystosis · Electron microscopy · Foamy macrophages · Gepirone · Lung · Phospholipidosis · Physicochemical calculated parameters · Piperazines · Sprague-Dawley rats · gepirone · piperazine · animal experiment · animal model · article · cell proliferation · cell type · controlled study · electron microscopy · histiocytosis · lipidosis · lung alveolus epithelium · lung alveolus macrophage · lymphoid tissue · macrophage activation · male · nonhuman · partition coefficient · pKa · prediction · rat · Administration, Oral · Animals · Antidepressive Agents · Chemistry, Physical · Diet · Dose-Response Relationship, Drug · Female · Foam Cells · Humans · Lipidoses · Male · Phospholipids · Pulmonary Alveoli · Pyrimidines · Rats · Rats, Sprague-Dawley · Toxicity Tests · U937 Cells · Animalia
[Abstract]

3 Suppression of the acute inflammatory response of porcine alveolar- and liver macrophages
article 2000    
Author: Izeboud, C.A. · Monshouwer, M. · Witkamp, R.F. · Miert, A.S.J. van
Keywords: Biology · Inflammation · LPS · Macrophages · Porcine · TNF-α · animal cell · animal disease · article · immune response · liver metabolism · lung alveolus macrophage · macrophage activation · nonhuman · Animals · Cell Culture Techniques · Cytokines · Inflammation · Lipopolysaccharides · Liver · Macrophage Activation · Macrophages, Alveolar · Nitric Oxide · Reactive Oxygen Species · Receptors, Adrenergic, beta · Swine · Animalia · Mammalia · Suidae
[Abstract]

4 Disposition of 14C-α-cyclodextrin in germ-free and conventional rats
article 2004    
Author: Ommen, B. van · Bie, A.T.H.J. de · Bär, A.
Keywords: Biology · Physiological Sciences · alpha cyclodextrin · carbon 14 · alpha cyclodextrin derivative · alpha-cyclodextrin · carbon · cyclodextrin · animal experiment · animal tissue · article · blood analysis · carcass · controlled study · dietary fiber · female · fermentation · gastrointestinal tract · germfree animal · high performance liquid chromatography · intestine flora · isotope labeling · kidney tubule excretion · lung alveolus carbon dioxide tension · male · metabolic regulation · nonhuman · priority journal · radioisotope distribution · rat · rat strain · small intestine absorption · species comparison · stomach content · animal · blood · drug detoxification · intravenous drug administration · oral drug administration · tissue distribution · urine · Wistar rat · Mammalia · Microbiota · Rattus norvegicus · Administration, Oral · alpha-Cyclodextrins · Animals · Carbon Radioisotopes · Cyclodextrins · Female · Germ-Free Life · Injections, Intravenous · Male · Metabolic Detoxication, Drug · Rats · Rats, Wistar · Tissue Distribution
[Abstract]

5 Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents. III. PBPK modeling of white spirit constituents as a tool for integrating animal and human test data
article 2007    
Author: Hissink, A.M. · Krüse, J. · Kulig, B.M. · Verwei, M. · Muijser, H. · Salmon, F. · Leenheers, L.H. · Owen, D.E. · Lammers, J.H.C.M. · Freidig, A.P. · McKee, R.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Central nervous system effects · Cross-species extrapolation · n-Decane · Occupational exposure limits · PBPK model · Toxicokinetics · Trimethyl benzene · White spirit · 1,2,4 trimethylbenzene · decane · hydrocarbon · organic solvent · stoddard solvent · unclassified drug · adult · animal experiment · article · behavior · blood analysis · brain · central nervous system · cognition · controlled study · exposure · human · human experiment · in vitro study · lung alveolus · male · nonhuman · partition coefficient · priority journal · rat · toxicokinetics · validation study · Adult · Alkanes · Aniline Compounds · Animals · Behavior, Animal · Body Weight · Brain · Dose-Response Relationship, Drug · Humans · Hydrocarbons · Male · Models, Animal · Models, Biological · Rats · Rats, Wistar · Solvents · Time Factors · Tissue Distribution · Animalia · Rattus
[Abstract]

6 Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma
article 2006    
Author: Valstar, D.L. · Schijf, M.A. · Nijkamp, F.P. · Storm, G. · Arts, J.H.E. · Kuper, C.F. · Bloksma, N. · Henricks, P.A.J.
Keywords: Health · Toxicology and Applied Pharmacology · Airway inflammation · Alveolar macrophages · Early asthmatic response · Occupational asthma · Trimellitic anhydride · clodronic acid · immunoglobulin E · interleukin 6 · liposome · trimellitic anhydride · tumor necrosis factor alpha · animal cell · animal experiment · animal model · animal tissue · article · body weight · cell function · controlled study · disease severity · female · immunoglobulin blood level · lung alveolus macrophage · lung function · lung injury · lung lavage · lymphocyte depletion · nonhuman · occupational asthma · organ weight · rat · respiratory tract inflammation · Allergens · Analysis of Variance · Animals · Asthma · Cytokines · Disease Models, Animal · Female · Immunoglobulin E · Lung · Macrophages, Alveolar · Occupational Diseases · Phthalic Anhydrides · Rats · Rats, Inbred BN · Respiratory Function Tests · Statistics, Nonparametric · Animalia · Rattus norvegicus
[Abstract]

7 Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin
article 2006    
Author: Valstar, D.L. · Schijf, M.A. · Arts, J.H.E. · Kuper, C.F. · Nijkamp, F.P. · Storm, G. · Bloksma, N. · Henricks, P.A.J.
Keywords: Health · Toxicology and Applied Pharmacology · Airway inflammation · Alveolar macrophages · Early asthmatic response · Occupational asthma · Trimellitic anhydride · albumin · clodronic acid · immunoglobulin E · liposome · trimellitic anhydride · animal experiment · animal model · animal tissue · article · controlled study · female · inflammation · inflammatory cell · inhalation · lung alveolus macrophage · lung fluid · lung function · lung lavage · lung minute volume · nonhuman · occupational asthma · occupational exposure · priority journal · rat · sensitization · tidal volume · Allergens · Animals · Asthma · Bone Density Conservation Agents · Bronchial Hyperreactivity · Bronchoalveolar Lavage Fluid · Cattle · Clodronic Acid · Cytokines · Drug Therapy, Combination · Female · Haptens · Immunoglobulin E · Liposomes · Macrophages, Alveolar · Occupational Diseases · Phthalic Anhydrides · Protein Binding · Rats · Rats, Inbred BN · Respiratory Function Tests · Serum Albumin, Bovine · Rattus norvegicus
[Abstract]

8 Human CD46-transgenic mice in studies involving replication-incompetent adenoviral type 35 vectors
article 2006    
Author: Verhaagh, S. · Jong, E. de · Goudsmit, J. · Lecollinet, S. · Gillissen, G. · Vries, M. de · Leuven, K. van · Que, I. · Ouwehand, K. · Mintardjo, R. · Weverling, G.J. · Radošević, K. · Richardson, J. · Eloit, M. · Lowik, C. · Quax, P. · Havenga, M.
Keywords: Biology · Biomedical Research · Adenovirus vector · Beta galactosidase · CD8 antigen · Gag protein · Luciferase · Membrane cofactor protein · Simian immunodeficiency virus vaccine · Animal cell · Animal experiment · Antigen expression · Antigen function · Camera · CD8+ T lymphocyte · Cellular immunity · Controlled study · Dendritic cell · Drug potency · Drug safety · Female · Gene expression · Human adenovirus · Imaging system · Kidney cell · Lung alveolus epithelium · Male · Mouse · Mouse strain · Muscle cell · Nonhuman · Receptor affinity · Transgenic mouse · Viral gene delivery system · Virus replication · Wild type · Adenoviruses, Human · Animals · Antigens, CD46 · Genetic Vectors · Humans · Mice · Mice, Transgenic · Virus Replication · Adenoviridae · Animalia · Human adenovirus · Mus musculus · Simian immunodeficiency virus
[Abstract]

9 Dip coating of air purifier ceramic honeycombs with photocatalytic TiO2 nanoparticles: A case study for occupational exposure
article 2018    
Author: Koivisto, A.J. · Kling, K.I. · Fonseca, A.S. · Brostrøm Bluhme, A. · Moreman, M. · Yu, M. · Costa, A.L. · Giovanni, B. · Ortelli, S. · Fransman, W. · Vogel, U. · Jensen, K.A.
Keywords: Nutrition · Nanomaterial · Titanium dioxide · Indoor aerosol modeling · Inhalation exposure · Emission rate · Air cleaners · Air purification · Biological organs · Ceramic materials · Coatings · Honeycomb structures · Industrial hygiene · Nanoparticles · Nanostructured materials · Occupational risks · Particulate emissions · Respiratory system · Titanium dioxide · Deposited surface areas · Emission rates · Environmental exposure · Indoor aerosol model · Inhalation exposure · Nanoparticle suspension · National institute for occupational safety and healths · Occupational exposure · Particles (particulate matter) · Titanium dioxide nanoparticle · Aerosol · Catalysis · Ceramics · Emission · Modeling · Nanomaterial · Nanoparticle · Photochemistry · Titanium · Bronchus · Case study · Controlled study · Lung alveolus · Material coating · No-observed-adverse-effect level · Particle size · Particulate matter · Photocatalysis · Physical chemistry · Prediction · Trachea · Work environment · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 9 of 9 found. | Sort by date