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1 Inhibition of matrix metalloproteinases by bisphosphonates may in part explain their effects in the treatment of multiple myeloma [6]
article 2000    
Author: Teronen, O. · Laitinen, M. · Salo, T. · Hanemaaijer, R. · Heikkilä, P. · Konttinen, Y.T. · Sorsa, T.
Keywords: Pharmacology · Antineoplastic Agents · Breast Neoplasms · Diphosphonates · Down-Regulation · Enzyme Inhibitors · Female · Humans · Male · Matrix Metalloproteinases · Multiple Myeloma · Neoplasm Metastasis

2 Exposure of human cartilage tissue to low concentrations of blood for a short period of time leads to prolonged cartilage damage: An in vitro study
article 2007    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · DNA content · Blood · Blood Proteins · Cartilage, Articular · Dose-Response Relationship, Drug · Extracellular Matrix Proteins · Humans · Matrix Metalloproteinases · Middle Aged · Proteoglycans · Time Factors
[Abstract]

3 Oral matrix metalloproteinase inhibition and arterial remodeling after balloon dilation: An intravascular ultrasound study in the pig
article 2001    
Author: Sierevogel, M.J. · Pasterkamp, G. · Velema, E. · Jaegere, P.P.T.de · Smet, B.J.G.L.de · Verheijen, J.H. · Kleijn, D.P.V.de · Borst, C.
Keywords: Health · Angioplasty · Metalloproteinases · Remodeling · Stenosis · Ultrasonics · Administration, Oral · Animals · Arteries · Balloon Dilatation · Enzyme Inhibitors · Hydroxamic Acids · Hyperplasia · Matrix Metalloproteinases · Swine · Tunica Intima · Ultrasonography, Interventional
[Abstract]

4 Collagen degradation in the abdominal aneurysm: A conspiracy of matrix metalloproteinase and cysteine collagenases
article 2007    
Author: Abdul-Hussien, H. · Soekhoe, R.G.V. · Weber, E. · Thüsen, J.H. von der · Kleemann, R. · Mulder, A. · Hajo Van Bockel, J. · Hanemaaijer, R. · Lindeman, J.H.N.
Keywords: Health · Aged · Aortic Aneurysm, Abdominal · Blotting, Western · Collagen · Collagenases · Cysteine · Female · Humans · Immunohistochemistry · Male · Matrix Metalloproteinases · Protease Inhibitors · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger
[Abstract]

5 A novel and simple immunocapture assay for determination of gelatinase-B (MMP-9) activities in biological fluids : Saliva from patients with Sjögren's syndrome contain increased latent and active gelatinase-B levels
article 1998    
Author: Hanemaaijer, R. · Visser, H. · Konttinen, Y.T. · Koolwijk, P. · Verheijen, J.H.
Keywords: Health · Activity assay · Gelatinase B · Matrix metalloproteinases (MMP) · Sjogren's syndrome · Urokinase · Animals · Antibodies, Monoclonal · Antibody Specificity · Collagenases · Female · Humans · Immunoassay · Matrix Metalloproteinase 9 · Mice · Mice, Inbred BALB C · Saliva · Sensitivity and Specificity · Sjogren's Syndrome · Tissue Inhibitor of Metalloproteinase-2 · Animalia
[Abstract]

6 Extracellular matrix components and regulators in the airway smooth muscle in asthma
article 2008    
Author: Araujo, B.B. · Dolhnikoff, M. · Silva, L.F.F. · Elliot, J. · Lindeman, J.H.N. · Ferreira, D.S. · Mulder, A. · Gomes, H.A.P. · Fernezlian, S.M. · James, A. · Mauad, T.
Keywords: Airway smooth muscle · Extracellular matrix · Fatal asthma · Metalloproteinases · Remodelling · Tissue inhibitor of metalloproteinase · Adolescent · Adult · Asthma · Bronchi · Case-Control Studies · Extracellular Matrix · Female · Humans · Male · Matrix Metalloproteinases · Middle Aged · Muscle, Smooth · Tissue Inhibitor of Metalloproteinases
[Abstract]

7 Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
article 2003    
Author: Laan, W.H. van der · Quax, P.H.A. · Seemayer, C.A. · Huisman, L.G.M. · Pieterman, E.J. · Grimbergen, J.M. · Verheijen, J.H. · Breedveld, F.C. · Gay, R.E. · Gay, S. · Huizinga, T.W.J. · Pap, T.
Keywords: Adenoviridae · Animals · Arthritis, Rheumatoid · Cartilage, Articular · Cell Division · Fibroblasts · Gene Expression · Gene Therapy · Genetic Vectors · Humans · Matrix Metalloproteinases · Mice · Mice, SCID · Synovial Membrane · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Transduction, Genetic · Adenoviridae · Animalia
[Abstract]

8 Relaxin stimulates MMP-2 and α-smooth muscle actin expression by human periodontal ligament cells
article 2008    
Author: Henneman, S. · Bildt, M.M. · Groot, J. de · Kuijpers-Jagtman, A.M. · Von den Hoff, J.W.
Keywords: Biology Nutrition · α-SMA · Fibroblasts · MMP · Periodontal ligament · Relaxin · Gelatinase · Matrix metalloproteinase · Relaxin · Tissue inhibitor of metalloproteinase · Article · Cell culture · Chemistry · Cytology · Drug effect · Enzymology · Female · Fibroblast · Gene expression · Genetics · Human · Male · Metabolism · Periodontal ligament · Cells, Cultured · Female · Fibroblasts · Gelatinases · Gene Expression · Humans · Male · Matrix Metalloproteinases · Periodontal Ligament · Relaxin · Tissue Inhibitor of Metalloproteinases
[Abstract]

9 Effect of collagen turnover and matrix metalloproteinase activity on healing of venous leg ulcers
article 2008    
Author: Meyer, F.J. · Burnand, K.G. · Abisi, S. · TeKoppele, J.M. · Els, B. van · Smith, A.
Keywords: Health · Collagen type 3 · Interstitial collagenase · Matrix metalloproteinase · Stromelysin · Peptide fragment · Clinical article · Collagen synthesis · controlled study · Enzyme activity · Leg ulcer · Priority journal · Protein analysis · Skin biopsy · Aged · Comparative study · Enzymology · Metabolism · Physiology · Varicosis · Aged · Collagen · Female · Humans · Male · Matrix Metalloproteinases · Peptide Fragments · Procollagen · Skin · Varicose Ulcer · Wound Healing
[Abstract]

10 Degenerated and healthy cartilage are equally vulnerable to blood-induced damage
article 2008    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Theobald, M. · Lafeber, F.P.J.G.
Keywords: Health · Matrix metalloproteinase · Proteoglycan · Aged · Article · Blood · Cartilage cell · Cartilage degeneration · Controlled study · Enzyme activity · Female · Hemarthrosis · Human · Human tissue · Male · Osteoarthritis · Priority journal · Proteoglycan synthesis · Aged · Blood · Cartilage, Articular · Chondrocytes · Female · Hemarthrosis · Humans · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis · Proteoglycans · Tissue Culture Techniques · Food and Nutrition · Healthy Living
[Abstract]

11 Urinary matrix metalloproteinases reflect renal damage in anti-neutrophil cytoplasm autoantibody-associated vasculitis
article 2007    
Author: Sanders, J.S.F. · Huitema, M.G. · Hanemaaijer, R. · Goor, H. van · Kallenberg, C.G.M. · Stegeman, C.A.
Keywords: Biology · ANCA-associated vasculitis · Crescentic glomerulonephritis · Immunohistochemistry · MMP-2 · MMP-9 · Plasma levels · TIMP-1 · Urinary levels · C reactive protein · Adult · Aged · Aged, 80 and over · Antibodies, Antineutrophil Cytoplasmic · C-Reactive Protein · Creatine · Enzyme-Linked Immunosorbent Assay · Female · Humans · Immunohistochemistry · Kidney Diseases · Kidney Glomerulus · Male · Matrix Metalloproteinases · Middle Aged · Proteinuria · Tissue Inhibitor of Metalloproteinase-1 · Vasculitis
[Abstract]

12 Matrix degradation by chondrocytes cultured in alginate : IL-1β induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation
article 1998    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M. de · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Matrix degradation · Matrix metalloproteinases · alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid · collagen · glycosaminoglycan · interleukin 1beta · metalloproteinase · proteoglycan · cartilage cell · degradation · enzyme synthesis · extracellular matrix · Alginates · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Interleukin-1 · Metalloendopeptidases · Microspheres · Proteoglycans
[Abstract]

13 Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction
article 2009    
Author: Borne, S.W.M. van den · Cleutjens, J.P.M. · Hanemaaijer, R. · Creemers, E.E. · Smits, J.F.M. · Daemen, M.J.A.P. · Blankesteijn, W.M.
Keywords: Biology · Biomedical Research · Infarct rupture · Inflammation · Matrix metalloproteinases · MMP activity assay · MMP immunohistochemistry · Myocardial infarction · gelatinase A · gelatinase B · neutrophil collagenase · tissue inhibitor of metalloproteinase 1 · adult · aged · article · clinical article · controlled study · enzyme activity · female · heart · heart disease · heart infarction · human · human tissue · immunohistochemistry · infarct rupture · inflammatory cell · male · priority journal · zymography · Aged · Aged, 80 and over · Cell Count · Female · Heart Rupture, Post-Infarction · Humans · Immunohistochemistry · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Middle Aged · Myocardial Infarction · Myocarditis
[Abstract]

14 Contribution of collagen network features to functional properties of engineered cartilage
article 2008    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Linden, J.C. van der · Zuurmond, A.M. · Weinans, H. · Verhaar, J.A.N. · Osch, G.J.V.M. van · Groot, J. de
Keywords: Health · Cartilage · Chondrocyte · Collagen · Crosslinks · Mechanical properties · 3 aminopropionitrile · alginic acid · collagen · interstitial collagenase · water · animal cell · animal cell culture · article · articular cartilage · cartilage cell · cartilage matrix · cattle · collagen degradation · controlled study · cross linking · nonhuman · priority journal · protein degradation · rigidity · tissue engineering · water retention · Alginates · Aminopropionitrile · Animals · Biomechanics · Cartilage, Articular · Cattle · Cell Count · Cells, Cultured · Chondrocytes · Extracellular Matrix · Fibrillar Collagens · Gene Expression · Matrix Metalloproteinases · Osteoarthritis · Permeability · Phenotype · Regeneration · Stress, Mechanical · Time Factors · Tissue Engineering
[Abstract]

15 Chemically modified tetracyclines stimulate matrix metalloproteinase-s production by periodontal ligament cells
article 2006    
Author: Bildt, M.M. · Snoek-van Beurden, A.M.P. · Groot, J. de · El, B. van · Kuijpers-Jagtman, A.M. · Hoff, J.W. van den
Keywords: Biology · Biomedical Research · Chemically modified tetracyclines · Gelatin zymography · Matrix metalloproteinases · Periodontal ligament · DNA · Enzyme inhibitor · Gelatin · Gelatinase A · Gelatinase B · Recombinant protein · Tetracycline derivative · Analysis of variance · Iosynthesis · Cell culture · Chemistry · Drug antagonism · Drug effect · Human · Metabolism · Nonparametric test · Periodontal ligament · Polyacrylamide gel electrophoresis · Western blotting · Analysis of Variance · Blotting, Western · Cells, Cultured · DNA · Electrophoresis, Polyacrylamide Gel · Enzyme Inhibitors · Gelatin · Humans · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Periodontal Ligament · Recombinant Proteins · Statistics, Nonparametric · Tetracyclines
[Abstract]

16 Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1
article 2002    
Author: Lamfers, M.L.M. · Grimbergen, J.M. · Aalders, M.C. · Havenga, M.J. · Vries, M.R. de · Huisman, L.G.M. · Hinsbergh, V.W.M. van · Quax, P.H.A.
Keywords: Biology · Adenovirus · Matrix metalloproteinases · Neointima formation · Plasmin(ogen) · Urokinase-type plasminogen activator · Adenovirus · Adenoviridae · Animals · Cell Division · Cell Membrane · Cell Movement · Cells, Cultured · CHO Cells · Collagenases · Cricetinae · Culture Media, Conditioned · Enzyme Activation · Flow Cytometry · Gene Transfer Techniques · Humans · Matrix Metalloproteinase 13 · Muscle, Smooth, Vascular · Protein Structure, Tertiary · Receptors, Cell Surface · Recombinant Fusion Proteins · RNA, Messenger · Saphenous Vein · Tissue Inhibitor of Metalloproteinase-1 · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

17 Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: The role of advanced glycation end products
article 2001    
Author: Groot, J. de · Verzijl, N. · Wenting-Van Wijk, M.J.G. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · glycosaminoglycan · matrix metalloproteinase · pentosidine · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · colorimetry · controlled study · disease course · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · protein degradation · rheumatoid arthritis · synovial fluid · Adult · Aged · Aged, 80 and over · Aging · Animals · Arginine · Arthritis, Rheumatoid · Cartilage, Articular · Cattle · Chromatography, High Pressure Liquid · Glycosaminoglycans · Humans · Knee Joint · Lysine · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Phenylmercuric Acetate · Ribose · Synovial Fluid
[Abstract]

18 Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes
article 2001    
Author: Groot, J. de · Verzijl, N. · Budde, M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Advanced glycation end product · Alginate culture · Cartilage · Chondrocyte · Collagen · Matrix metalloproteinase · Turnover · advanced glycation end product · alginic acid · collagen · matrix metalloproteinase · ribose · animal cell · article · articular cartilage · cartilage cell · cattle · cell culture · collagen defect · collagen degradation · collagen synthesis · controlled study · culture medium · enzyme activity · extracellular matrix · nonhuman · osteoarthritis · priority journal · reaction time · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Enzyme Precursors · Extracellular Matrix · Glycosylation End Products, Advanced · Matrix Metalloproteinases · Osteoarthritis · Ribose · Bovinae
[Abstract]

19 Cathepsin K is the principal protease in giant cell tumor of bone
article 2004    
Author: Lindeman, J.H.N. · Hanemaaijer, R. · Mulder, A. · Dijkstra, P.D.S. · Szuhai, K. · Bromme, D. · Verheijen, J.H. · Hogendoorn, P.C.W.
Keywords: Health · Cathepsin K · Cathepsin L · Cathepsin S · Collagen · Collagenase 3 · Gelatinase B · Matrix metalloproteinase 14 · Messenger RNA · Proteinase · Bone tumor · Clinical article · Enzyme activity · Human tissue · Immunohistochemistry · Metaphysis · Osteolysis · Protein expression · Real time polymerase chain reaction · Adult · Bone Neoplasms · Cathepsins · Collagenases · Cysteine Endopeptidases · Female · Giant Cell Tumor of Bone · Humans · Immunoenzyme Techniques · Male · Matrix Metalloproteinase 13 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Middle Aged · Osteoclasts · Osteolysis · RNA, Messenger
[Abstract]

20 Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix
article 2003    
Author: Collen, A. · Hanemaaijer, R. · Lupu, F. · Quax, P.H.A. · Lent, N. van · Grimbergen, J. · Peters, E. · Koolwijk, P. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Adenoviridae · Aprotinin · Cells, Cultured · Collagen · Culture Media · Defective Viruses · Drug Synergism · Endothelial Growth Factors · Endothelium, Vascular · Fibrin · Fibroblast Growth Factor 2 · Genetic Vectors · Heart Diseases · Humans · Intercellular Signaling Peptides and Proteins · Lymphokines · Matrix Metalloproteinase 1 · Matrix Metalloproteinase 2 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Neovascularization, Pathologic · Neovascularization, Physiologic · Phenylalanine · Protease Inhibitors · Thiophenes · Thrombosis · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Transduction, Genetic · Tumor Necrosis Factor-alpha · Vascular Endothelial Growth Factor A · Vascular Endothelial Growth Factors
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 35 found. Next | Sort by date