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Showing 1 to 18 of 18 found. | Sort by date

1 Calcium metabolism in sarcoidosis: a follow-up study with respect to parathyroid hormone and vitamin D metabolites
article 1986    
Author: Alberts, C. · Berg, H. van den
Keywords: Calcium metabolism · Parathyroid hormone · Sarcoidosis · Vitamin D metabolites

2 Role of amino acids in rheumatoid arthritis studied by metabolomics
article 2019    
Author: He, M. · Harms, A.C. · Wijk, E. van · Wang, M. · Berger, R. · Koval. S. · Hankemeier, T. · Greef, J. van der
Keywords: Amine metabolites · Collagen-induced arthritis · Mouse model · Systems biology · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

3 Comprehensive analysis of the intracellular metabolism of antiretroviral nucleosides and nucleotides using liquid chromatography-tandem mass spectrometry and method improvement by using ultra performance liquid chromatography
article 2011    
Author: Coulier, L. · Gerritsen, H. · Kampen, J.J.A. van · Reedijk, M.L. · Luider, T.M. · Osterhaus, A.D.M.E. · Gruters, R.A. · Brüll, L.
Keywords: Nutrition · Antiretroviral drugs · HIV · Ion-pair LC-MS/MS · NRTI · Phosphorylated metabolites · UPLC · Life Triskelion BV · QS - Quality & Safety AR - Analytical Research · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

4 Effect of galactooligosaccharides and Bifidobacterium animalis Bb-12 on growth of Lactobacillus amylovorus DSM 16698, microbial community structure, and metabolite production in an in vitro colonic model set up with human or pig microbiota
article 2013    
Author: Martinez, R.C.R. · Cardarelli, H.R. · Borst, W. · Albrecht, S. · Schols, H. · Gutiérrez, O.P. · Maathuis, A.J.H. · Melo Franco, B.D.G. de · Martinis, E.C.P. de · Zoetendal, E.G. · Venema, K. · Saad, S.M.I. · Smidt, H.
Keywords: Biology · 16S rRNA gene-targeted qPCR · Galactooligosaccharides · Metabolites · PCR-DGGE · Probiotic · TIM-2 · Food and Nutrition · Healthy Living · Life · PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

5 Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R Study
article 2015    
Author: Spaan, S. · Pronk, A. · Koch, H.M. · Jusko, T.A. · Jaddoe, V.M.W. · Shaw, P.A. · Tiemeier, H.M. · Hofman, A. · Pierik F.H. · Longnecker M.P.
Keywords: Nutrition · Organophosphate pesticide metabolites · Environmental exposure · Variability; reliability · Cohort study · Epidemiologic studies · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

6 Higher mass loadability in comprehensive two-dimensional gas chromatography-mass spectrometry for improved analytical performance in metabolomics analysis
article 2008    
Author: Koek, M.M. · Muilwijk, B. · Stee, L.L.P. van · Hankemeier, T.
Keywords: Biology · Column diameter · Comprehensive two-dimensional gas chromatography · GC × GC-TOFMS · Mass loadability · Metabolic profiling · Metabolites · Metabolomics · Overloading · Sample capacity · Stationary phase film thickness · Time-of-flight mass spectrometry · Concentration (process) · Film thickness · Gas chromatography · Mass spectrometry · Sampling · Column diameter · Comprehensive two-dimensional gas chromatography · Metabolic profiling · Sample capacity · Stationary phase film thickness · Time-of-flight mass spectrometry · Metabolites · drug metabolite · analytic method · article · autoanalysis · comparative study · concentration (parameters) · feasibility study · film · gas chromatography · mass · mass fragmentography · metabolomics · priority journal · sample · Animals · Cattle · Gas Chromatography-Mass Spectrometry · Glucose · Molecular Weight · Reference Standards · Serum

7 Simultaneous quantitative analysis of metabolites using ion-pair liquid chromatography-electrospray ionization mass spectrometry
article 2006    
Author: Coulier, L. · Bas, R. · Jespersen, S. · Verheij, E. · Werf, M.J. van der · Hankemeier, T.
Keywords: Biology · Biotechnology · Chemical analysis · Esters · Liquid chromatography · Mass spectrometry · Optimization · PH effects · Electrospray ionization mass spectrometry · Energy charge · Ion pair liquid chromatography · Polar metabolites · Metabolites · Acyl coenzyme A · Ammonium acetate · Bisphosphonic acid derivative · Hexylamine · Methanol · Nucleotide · Sugar bisphosphonate · Sugar nucleotide · Unclassified drug · Water · Acidity · Alkalinity · Analytic method · Bacillus subtilis · Electrospray mass spectrometry · Energy expenditure · Escherichia coli · Ion pair chromatography · Metabolite · Metabolomics · Nonhuman · Process optimization · Quantitative assay · Reproducibility · Sampling · Validation process · Amines · Bacillus subtilis · Chromatography, Liquid · Coenzyme A · Escherichia coli · Esters · Hydrogen-Ion Concentration · Nucleotides · Reproducibility of Results · Spectrometry, Mass, Electrospray Ionization · Sugar Phosphates
[Abstract]

8 New figures of merit for comprehensive functional genomics data: The metabolomics case
article 2011    
Author: Batenburg, M.F. van · Coulier, L. · Eeuwijk, F. van · Smilde, A.K. · Westerhuis, J.A.
Keywords: Nutrition · Comprehensive measurement · Concentration levels · Figure of merit · Figures of merits · Functional genomics · Gas chromatography/mass spectrometry · Instrumental noise · Liquid chromatography/mass spectrometry · Metabolomics · Pre-Treatment · Biomolecules · Chromatography · Metabolism · Metabolites · Potential flow · Spectrometry · Measurement errors · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

9 Analytical possibilities for the detection of stanozolol and its metabolites
article 2002    
Author: Poelmans, S. · Wasch, K. de · Brabander, H.F. de · Wiele, M. van de · Courtheyn, D. · Ginkel, L.A. van · Sterk, S.S. · Delahaut, Ph. · Dubois, M. · Schilt, R. · Nielen, M. · Vercammen, J. · Impens, S. · Stephany, R. · Hamoir, T. · Pottie, G. · Poucke, C. van · Peteghem, C. van
Keywords: Health · Analytical research · Anabolic steroids · GC-MS · LC-MS · Metabolites · Stanozolol · anabolic agent · chemical compound · stanozolol · chemistry · conference paper · drug blood level · drug metabolism · extraction · gas chromatography · hydrolysis · immunoaffinity chromatography · kidney clearance · liquid chromatography · liquid liquid extraction · literature · mass spectrometry · metabolite · nonhuman · priority journal · solid phase extraction · urinary excretion · urine · Animalia
[Abstract]

10 Dermal absorption of chlorpyrifos in human volunteers
article 2005    
Author: Meuling, W.J. · Ravensberg, L.C. · Roza, L. · Hemmen, J.J. van
Keywords: Health · Analytical research · Occupational exposure · Percutaneous penetration · Pesticide · Urinary metabolites · Volunteers · alcohol · chlorpyrifos · pyridinol · adult · article · clinical study · controlled study · dilution · forearm · fractionation · good clinical practice · human · human experiment · informed consent · male · methodology · occupational exposure · practice guideline · skin absorption · skin penetration · urinalysis · urinary excretion · volunteer · Adult · Chlorpyrifos · Human Experimentation · Humans · Male · Occupational Exposure · Pesticides · Skin Absorption
[Abstract]

11 Microbial transglutaminase production by Streptoverticillium mobaraense: Analysis of amino acid metabolism using mass balances
article 1998    
Author: Zhu, Y. · Rinzema, A. · Bonarius, H.P.J. · Tramper, J. · Bol, J.
Keywords: Nutrition · Mass balancing · Metabolic flow · Metabolite balancing · Microbial transglutaminase · Streptoverticillium mobaraense · Amino acids · Biosynthesis · Crosslinking · Enzymes · Metabolites · Mass balances · Microbial transglutaminase · Biotechnology · Amino acid · Carbon dioxide · Glucose · Nitrogen · Protein glutamine gamma glutamyltransferase · Amino acid metabolism · Amino acid transport · Bacterial metabolism · Cross linking · Enzyme synthesis · Fermentation · Glucose intake · Nonhuman · Streptomycetaceae · Streptoverticillium mobaraense
[Abstract]

12 A fungal biofilm reactor based on metal structured packing improves the quality of a Gla::GFP fusion protein produced by Aspergillus oryzae
article 2015    
Author: Zune, Q. · Delepierre, A. · Gofflot, S. · Bauwens, J. · Twizere, J.C. · Punt, P.J. · Francis, F. · Toye, D. · Bawin, T. · Delvigne, F.
Keywords: Nutrition · Fungal biofilm · Bioreactor · Scale-up · Recombinant protein · Antigen-antibody reactions · Aspergillus · Biofilms · Biomass · Bioreactors · Electrophoresis · Enzyme activity · Fermentation · Fungi · Metabolites · Physiology · Recombinant proteins · Shear stress · Comparative analysis · Extracellular medium · Green fluorescent protein · Physiological mechanisms · Secondary metabolites · Solid-state fermentation · Submerged fermentation · Proteins · Amylase · Glucan 1,4 alpha glucosidase · Glucoamylase green fluorescent protein fusion protein · Green fluorescent protein · Hybrid protein · Unclassified drug · Fermentation · Fungus · Metal · Physiological response · Protein · Qualitative analysis · Recirculating system · Recombination · Secondary metabolite · Alkalinization · Amino acid sequence · Aspergillus niger · Aspergillus oryzae · Autolysis · Biofilm reactor · Biotransformation · Carbon source · Controlled study · Enzyme activity · Extracellular space · Fungal biomass · Fungal colonization · Fungus culture · Fungus growth · Glucose intake · Hydrolysis · Immersion · Immunodetection · Nonhuman · PH measurement · Protein analysis · Shear stress · Solid state fermentation · Submerged fermentation · Western blotting · Food and Nutrition · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

13 The influence of microbial metabolites on human intestinal epithelial cells and macrophages in vitro
article 2005    
Author: Nuenen, M.H.M.C. van · Ligt, R.A.F. de · Doornbos, R.P. · Woude, J.C.J. van der · Kuipers, E.J. · Venema, K.
Keywords: Nutrition · Physiological Sciences · Interleukin-10 · Intestinal epithelial cells · Macrophages · Microbial metabolites · Tumour necrosis factor-α · ammonia · butyric acid · cytokine · interleukin 10 · tumor necrosis factor alpha · valeric acid · article · cell strain CACO 2 · concentration (parameters) · cytokine release · electric resistance · enteritis · epithelium cell · human · human cell · immunity · macrophage · metabolism · metabolite · physiology · priority journal · Ammonium Chloride · Butyrates · Caco-2 Cells · Epithelial Cells · Humans · Immunity, Mucosal · Inflammatory Bowel Diseases · Interleukin-10 · Intestines · Macrophages · Pentanoic Acids · Tumor Necrosis Factor-alpha · U937 Cells
[Abstract]

14 The metabolic activity of fecal microbiota from healthy individuals and patients with inflammatory bowel disease
article 2004    
Author: Nuenen, M.H.M.C. van · Venema, K. · Woude, J.C.J. van der · Kuipers, E.J.
Keywords: Nutrition · Physiological Sciences · Fermentation · In vitro model · Inflammatory bowel disease · Metabolites · Microbial activity · ammonia · branched chain fatty acid · fatty acid · lactic acid · phenol derivative · short chain fatty acid · unclassified drug · adult · article · carbohydrate metabolism · chronicity · clinical article · controlled study · enteritis · fatty acid synthesis · feces microflora · fermentation · human · in vitro study · metabolite · microbial metabolism · model · nonhuman · normal human · priority journal · protein degradation · Adult · Ammonia · Bacteria · Colitis, Ulcerative · Colon · Crohn Disease · Fatty Acids · Fatty Acids, Volatile · Feces · Fermentation · Humans · Lactic Acid · Middle Aged
[Abstract]

15 Bioconversion of red ginseng saponins in the gastro-intestinal tract in vitro model studied by high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonance mass spectrometry
article 2009    
Author: Kong, H. · Wang, M. · Venema, K. · Maathuis, A. · Heijden, R. van der · Greef, J. van der · Xu, G. · Hankemeier, T.
Keywords: Biology · Analytical research · Biomedical research · Acidic hydrolysis · Ginsenoside · HPLC-FTICR-MS · Intestinal bacteria · Metabolism · Metabolite profiling · Panax ginseng · Gastro-intestinal model · TIM · Acidic hydrolysis · Ginsenoside · HPLC-FTICR-MS · Intestinal bacteria · Metabolite profiling · Panax ginseng · Bacteriology · Biochemistry · Biomolecules · Body fluids · Chromatographic analysis · Chromatography · Cyclotron resonance · Cyclotrons · Electron cyclotron resonance · High performance liquid chromatography · High pressure liquid chromatography · Hydrolysis · Ion chromatography · Liquid chromatography · Mass spectrometers · Mass spectrometry · Metabolism · Metabolites · Pharmacodynamics · Plasmas · Resonance · Spectrometers · Spectrometry · Spectrum analysis · Technological forecasting · Thermal insulating materials · Fourier transforms · Chinese medicine · Biological Availability · Biotransformation · Chromatography, High Pressure Liquid · Fourier Analysis · Ginsenosides · Humans · Hydrogen-Ion Concentration · Intestine, Large · Mass Spectrometry · Models, Biological · Panax · Reproducibility of Results · Solid Phase Extraction · Panax ginseng
[Abstract]

16 Bioproduction of p-hydroxybenzoate from renewable feedstock by solvent-tolerant Pseudomonas putida S12
article 2007    
Author: Verhoef, S. · Ruijssenaars, H.J. · Bont, J.A.M.de · Wery, J.
Keywords: Biology · Biotechnology · Metabolic engineering · p-Hydroxybenzoate · Pseudomonas putida · Renewable feedstock · Solvent-tolerance · Cell culture · Fermentation · Glucose · Glycerol · Metabolites · Metabolic engineering · p-Hydroxybenzoate · Pseudomonas putida · Renewable feedstock · Solvent-tolerance · Aromatic compounds · 4 hydroxybenzoate 3 monooxygenase · 4 hydroxybenzoic acid · carbon · glucose · glycerol · para coumaric acid · phenylalanine ammonia lyase · solvent · tyrosine · article · bacterial strain · bacterium culture · chemostat · culture technique · enzyme activity · enzyme inactivation · fed batch fermentation · metabolic engineering · metabolite · nonhuman · nutrient · nutrient solution · priority journal · Pseudomonas putida · Pseudomonas putida s12 · reaction analysis · shake flask culture · steady state · Pseudomonas putida
[Abstract]

17 Development of an on-line high performance liquid chromatography detection system for human cytochrome P450 1A2 inhibitors in extracts of natural products
article 2007    
Author: Jeurissen, S.M.F. · Claassen, F.W. · Havlik, J. · Bouwmans, E.E. · Cnubben, N.H.P. · Sudhölter, E.J.R. · Rietjens, I.M.C.M. · Beek, T.A. van
Keywords: Biomedical Research · Methoxyresorufin-O-demethylase · Mixture analysis · On-line detection · P450 1A2 inhibitors · Bioassay · Cytology · Enzyme inhibition · Fluorescence · Metabolites · Screening · Methoxyresorufin-O-demethylase · Mixture analysis · On-line detection · P450 1A2 inhibitors · High performance liquid chromatography · basil extract · cytochrome P450 1A2 · cytochrome P450 1A2 inhibitor · cytochrome P450 inhibitor · fluvoxamine · furafylline · kava extract · methoxyresorufin · naringenin · natural product · plant extract · propranolol · resorufin · resorufin derivative · tacrine · article · assay · basil · demethylation · fluorescence · high performance liquid chromatography · metabolite · methoxyresorufin O demethylation assay · minimum detectable amount · online analysis · parameter · priority journal · screening · Biological Products · Chromatography, High Pressure Liquid · Cytochrome P-450 CYP1A2 · Cytochrome P-450 Enzyme System · Enzyme Inhibitors · Humans · Inhibitory Concentration 50 · Kava · Methanol · Ocimum basilicum · Online Systems · Oxidoreductases · Plant Extracts · Spectrometry, Fluorescence · Spectrophotometry, Ultraviolet · Ocimum basilicum · Piper methysticum
[Abstract]

18 Quantitative profiling of bile acids in biofluids and tissues based on accurate mass high resolution LC-FT-MS: Compound class targeting in a metabolomics workflow
article 2008    
Author: Bobeldijk, I. · Hekman, M. · Vries de- Weij, J.van der · Coulier, L. · Ramaker, R. · Kleemann, R. · Kooistra, T. · Rubingh, C. · Freidig, A. · Verheij, E.
Keywords: Analytical research · Accurate mass · Bile acids · Body fluids · High performance liquid chromatography · Metabolomics · Targeted metabolite profiling · Tissues · Acids · Arsenic compounds · Chlorine compounds · Cholesterol · Chromatographic analysis · Complexation · Electrospray ionization · Fourier transforms · High performance liquid chromatography · Histology · Ionization · Ionization of liquids · Liquid chromatography · Liquid phase epitaxy · Liver · Mass spectrometers · Mass spectrometry · Metabolites · Phase separation · Plasmas · Separation · Spectrometers · Spectrometry · Sulfate minerals · Accurate mass · Bile acid synthesis · Bile acids · Bio-fluids · Biological fluids · Cholesterol homeostasis · Chromatography-mass spectrometry · Electro spraying · Fourier Transform Mass Spectrometer · Generic methods · High resolutions · HPLC-MS · Human plasmas · Human urine · Linear ion trap · Metabolomics · Mouse liver · Pooled samples · Reversed-phase high performance · Sample preparations · Targeted metabolite profiling · Tissues · Body fluids · Bile acid · Glycine · Sulfate · Accuracy · Animal experiment · Animal tissue · Article · Bile acid synthesis · Body fluid · Cholesterol intake · Cholesterol liver level · Controlled study · Electrospray · Fourier transform mass spectrometry · Homeostasis · Human · Liver · Metabolite · Metabolomics · Nonhuman · Priority journal · Quantitative analysis · Reversed phase high performance liquid chromatography · Statistical significance · Tissue · Animals · Bile Acids and Salts · Cholesterol, Dietary · Chromatography, Liquid · Computational Biology · Fourier Analysis · Humans · Liver · Mass Spectrometry · Metabolism · Mice · Reproducibility of Results
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date