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1 Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors
article 2000    
Author: Hanemaaijer, R. · Verheijen, J.H. · Maguire, T.M. · Visser, H. · Toet, K. · McDermott, E. · O'Higgins, N. · Duffy, M.J.
Keywords: Breast Neoplasms · Catalysis · Enzyme-Linked Immunosorbent Assay · Fibroadenoma · Humans · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Prognosis
[Abstract]

2 Involvement of Membrane-Type Matrix Metalloproteinases (MT-MMPs) in capillary tube formation by human endometrial microvascular endothelial Cells: Role of MT3-MMP
article 2004    
Author: Plaisier, M. · Kapiteijn, K. · Koolwijk, P. · Fijten, C. · Hanemaaijer, R. · Grimbergen, J.M. · Mulder-Stapel, A. · Quax, P.H.A. · Helmerhorst, F.M. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Fibrin · Gelatinase A · Immunoglobulin G · Interstitial collagenase · Matrix metalloproteinase · Matrix metalloproteinase inhibitor · Membrane type 3 metalloproteinase · Membrane type 4 metalloproteinase · Messenger RNA · Unclassified drug · Urokinase · Adenovirus · Capillary · Cell culture · Controlled study · Endometrium cell · Endothelium cell · Enzyme inhibition · Enzyme regulation · Genetic transduction · Human cell · Immunohistochemistry · Prepuce · Protein expression · Vascular endothelium · Adenoviridae · Cells, Cultured · Collagen Type I · Endometrium · Endothelial Cells · Female · Humans · Matrix Metalloproteinase 16 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Neovascularization, Physiologic · Plasmin · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Urinary Plasminogen Activator · Adenoviridae
[Abstract]

3 Temporal changes in collagen composition and metabolism during rodent palatogenesis
article 2000    
Author: Mansell, J.P. · Kerrigan, J. · McGill, J. · Bailey, J. · TeKoppele, J. · Sandy, J.R.
Keywords: Biomedical Research · Collagen · Cross-linking · Matrix metalloproteinase · MMP · Palate · TIMP · gelatinase A · pyridinium derivative · pyridinoline · stromelysin · tissue inhibitor of metalloproteinase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · animal experiment · animal tissue · article · calcification · collagen metabolism · collagen synthesis · controlled study · cross linking · embryo · embryo development · enzyme activity · extracellular matrix · fetus · mouse · nonhuman · ossification · palate · priority journal · Animal · Calcification, Physiologic · Collagen · Cross-Linking Reagents · Embryo and Fetal Development · Female · Gelatinase A · Male · Palate · Rats · Rats, Wistar · Stromelysin 1 · Tissue Inhibitor-of Metalloproteinase-2 · Tissue-Inhibitor of Metalloproteinase-1 · Rodentia · Trixis
[Abstract]

4 A novel and simple immunocapture assay for determination of gelatinase-B (MMP-9) activities in biological fluids : Saliva from patients with Sjögren's syndrome contain increased latent and active gelatinase-B levels
article 1998    
Author: Hanemaaijer, R. · Visser, H. · Konttinen, Y.T. · Koolwijk, P. · Verheijen, J.H.
Keywords: Health · Activity assay · Gelatinase B · Matrix metalloproteinases (MMP) · Sjogren's syndrome · Urokinase · Animals · Antibodies, Monoclonal · Antibody Specificity · Collagenases · Female · Humans · Immunoassay · Matrix Metalloproteinase 9 · Mice · Mice, Inbred BALB C · Saliva · Sensitivity and Specificity · Sjogren's Syndrome · Tissue Inhibitor of Metalloproteinase-2 · Animalia
[Abstract]

5 Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
article 2003    
Author: Laan, W.H. van der · Quax, P.H.A. · Seemayer, C.A. · Huisman, L.G.M. · Pieterman, E.J. · Grimbergen, J.M. · Verheijen, J.H. · Breedveld, F.C. · Gay, R.E. · Gay, S. · Huizinga, T.W.J. · Pap, T.
Keywords: Adenoviridae · Animals · Arthritis, Rheumatoid · Cartilage, Articular · Cell Division · Fibroblasts · Gene Expression · Gene Therapy · Genetic Vectors · Humans · Matrix Metalloproteinases · Mice · Mice, SCID · Synovial Membrane · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Transduction, Genetic · Adenoviridae · Animalia
[Abstract]

6 Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms
article 2007    
Author: Nanni, S. · Melandri, G. · Hanemaaijer, R. · Cervi, V. · Tomasi, L. · Altimari, A. · Lent, N. van · Tricoci, P. · Bacchi, L. · Branzi, A.
Keywords: Health · Biomedical Research · biological marker · gelatinase A · gelatinase B · glucose · haptoglobin · matrix metalloproteinase · stromelysin · tissue inhibitor of metalloproteinase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · adult · article · controlled study · coronary artery atherosclerosis · correlation analysis · enzyme activity · enzyme blood level · exon · genetic polymorphism · glucose blood level · human · human tissue · inflammation · major clinical study · male · metabolic disorder · pathogenesis · priority journal · protein expression · protein localization
[Abstract]

7 Collagenase matrix metalloproteinase-8 expressed in atherosclerotic carotid plaques is associated with systemic cardiovascular outcome
article 2011    
Author: Peeters, W. · Moll, F.L. · Vink, A. · Spek, P.J. van der · Kleijn, D.P.V. de · Vries, J.-P.P.M. de · Verheijen, J.H. · Newby, A.C. · Pasterkamp, G.
Keywords: Health · Cardiovascular outcome · Carotid · Matrix metalloproteinase · Plaque · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

8 Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction
article 2009    
Author: Borne, S.W.M. van den · Cleutjens, J.P.M. · Hanemaaijer, R. · Creemers, E.E. · Smits, J.F.M. · Daemen, M.J.A.P. · Blankesteijn, W.M.
Keywords: Biology · Biomedical Research · Infarct rupture · Inflammation · Matrix metalloproteinases · MMP activity assay · MMP immunohistochemistry · Myocardial infarction · gelatinase A · gelatinase B · neutrophil collagenase · tissue inhibitor of metalloproteinase 1 · adult · aged · article · clinical article · controlled study · enzyme activity · female · heart · heart disease · heart infarction · human · human tissue · immunohistochemistry · infarct rupture · inflammatory cell · male · priority journal · zymography · Aged · Aged, 80 and over · Cell Count · Female · Heart Rupture, Post-Infarction · Humans · Immunohistochemistry · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Middle Aged · Myocardial Infarction · Myocarditis
[Abstract]

9 Extracellular proteolysis and the migrating vascular smooth muscle cell
article 1996    
Author: Leeuwen, R.T.J. van
Keywords: Biology · metalloproteinase · plasminogen activator · artery · cell migration · priority journal · protein degradation · review · smooth muscle fiber · vascular smooth muscle
[Abstract]

10 Gingival tissue and crevicular fluid co-operation in adult periodontitis
article 2006    
Author: Beklen, A. · Tüter, G. · Sorsa, T. · Hanemaaijer, R. · Virtanen, I. · Tervahartiala, T. · Konttinen, Y.T.
Keywords: Health · Collagenase · Gelatinase · Periodontitis · Stromelysin · collagenase · enzyme precursor · gelatinase · gelatinase B · metalloproteinase · neutrophil collagenase · procollagenase · progelatinase · stromelysin · adult · article · cell culture · enzyme activation · enzymology · female · fibroblast · gingiva · gingivitis · human · immunohistochemistry · male · middle aged · pathology · periodontitis · Adult · Cells, Cultured · Collagenases · Enzyme Activation · Enzyme Precursors · Female · Fibroblasts · Gelatinases · Gingiva · Gingival Crevicular Fluid · Humans · Immunohistochemistry · Male · Matrix Metalloproteinase 3 · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Metalloendopeptidases · Middle Aged · Periodontitis
[Abstract]

11 Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix
article 2003    
Author: Collen, A. · Hanemaaijer, R. · Lupu, F. · Quax, P.H.A. · Lent, N. van · Grimbergen, J. · Peters, E. · Koolwijk, P. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Adenoviridae · Aprotinin · Cells, Cultured · Collagen · Culture Media · Defective Viruses · Drug Synergism · Endothelial Growth Factors · Endothelium, Vascular · Fibrin · Fibroblast Growth Factor 2 · Genetic Vectors · Heart Diseases · Humans · Intercellular Signaling Peptides and Proteins · Lymphokines · Matrix Metalloproteinase 1 · Matrix Metalloproteinase 2 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Neovascularization, Pathologic · Neovascularization, Physiologic · Phenylalanine · Protease Inhibitors · Thiophenes · Thrombosis · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Transduction, Genetic · Tumor Necrosis Factor-alpha · Vascular Endothelial Growth Factor A · Vascular Endothelial Growth Factors
[Abstract]

12 Fluorogenic MMP activity assay for plasma including MMPs complexed to α2-macroglobulin
article 1999    
Author: Beekman, B. · Drijfhout, J.W. · Ronday, H.K. · TeKoppele, J.M.
Keywords: Health · Biomedical Research · Alpha 2 macroglobulin · Batimastat · Fluorescein · Matrix metalloproteinase · Arthritis · Cancer · Collagen degradation · Conference paper · Controlled study · Enzyme active site · Enzyme activity · Enzyme assay · Fluorescence analysis · Human · Molecular weight · Alpha-Macroglobulins · Collagen · Collagenases · Fluorescent Dyes · Humans · Kinetics · Matrix Metalloproteinase 13 · Metalloendopeptidases · Phenylalanine · Protease Inhibitors · Substrate Specificity · Thiophenes · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

13 Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer
article 2007    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Hawinkels, L.J.A.C. · Tschesche, H. · Duijn, W. van · Zuidwijk, K. · Reijden, J.J. van der · Hanemaaijer, R. · Griffioen, G. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biology · Biomedical Research · Activity assay · Cancer · Metalloproteinase · Prognosis · gelatinase B · lipocalin · matrix metalloproteinase inhibitor · tissue inhibitor of metalloproteinase 1 · adult · aged · article · autolysis · cancer survival · disease classification · enzyme activity · enzyme degradation · epithelium cell · female · human · human tissue · immunohistochemistry · major clinical study · male · multivariate analysis · priority journal · protein function · stomach cancer · tumor · univariate analysis · world health organization
[Abstract]

14 Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma
article 1996    
Author: Sier, C.F.M. · Kubben, F.J.G.M. · Ganesh, S. · Heerding, M.M. · Griffioen, G. · Hanemaaijer, R. · Krieken, J.H.J.M. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biology · Gastric carcinoma · Gelatinases · Matrix metalloproteinase · Quantitative zymography · gelatinase b · proteinase · adult · cancer classification · cancer invasion · cancer survival · clinical article · controlled study · histopathology · human tissue · metastasis · priority journal · prognosis · stomach carcinoma · stomach mucosa · Aged · Collagenases · Female · Gelatinases · Humans · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Metalloendopeptidases · Middle Aged · Stomach Neoplasms · Survival Rate
[PDF] [Abstract]

15 Matrix metalloproteinase (MMP)-9 type IV collagenase/gelatinase implicated in the pathogenesis of Sjogren's syndrome
article 1998    
Author: Konttinen, Y.T. · Halinen, S. · Hanemaaijer, R. · Sorsa, T. · Hietanen, J. · Ceponis, A. · Xu, J.W. · Manthorpe, R. · Whittington, J. · Larsson, Å. · Salo, T. · Kjeldsen, L. · Stenman, U.-H. · Eisen, A.Z.
Keywords: Health · Gelatinase associated lipocalin · Matrix metalloproteinase · Sjogren syndrome · Tissue inhibitor of metalloproteinases-1 (TIMP-1) · Tumor associated trypsin-2 (TAT-2) · Blotting, Western · Collagenases · Gelatinases · Humans · Immunohistochemistry · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Metalloendopeptidases · Microscopy, Electron · Polymerase Chain Reaction · Salivary Glands · Sjogren's Syndrome
[Abstract]

16 MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis
article 2004    
Author: Tchetverikov, I. · Ronday, H.K. · El, B. van · Kiers, G.H. · Verzijl, N. · TeKoppele, J.M. · Huizinga, T.W.J. · Groot, J. de · Hanemaaijer, R.
Keywords: alpha 2 macroglobulin · biological marker · gelatinase A · gelatinase B · hydroxyproline · interstitial collagenase · matrix metalloproteinase · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · aged · circulation · clinical article · collagen degradation · concentration (parameters) · controlled study · correlation analysis · enzyme activity · enzyme assay · enzyme linked immunosorbent assay · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · rheumatoid arthritis · sampling · serum · statistical significance · synovial fluid · Adult · Aged · alpha-Macroglobulins · Arthritis, Rheumatoid · Case-Control Studies · Collagenases · Enzyme Precursors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydroxyproline · Male · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Metalloendopeptidases · Middle Aged · Osteoarthritis, Knee · Statistics, Nonparametric · Synovial Fluid · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

17 Achilles tendinosis: Changes in biochemical composition and collagen turnover rate
article 2007    
Author: Mos, M. de · El, B. van · Groot, J. de · Jahr, H. · Schie, H.T.M. van · Arkel, E.R. van · Tol, H. · Heijboer, R. · Osch, G.J.V.M. van · Verhaar, J.A.N.
Keywords: Biology · Biomedical Research · Achilles tendon · Collagen · Crosslinks · Matrix metalloproteinase · Pentosidine · Tendinopathy · Tendinosis · collagen · collagen type 1 · collagen type 2 · lysine · matrix metalloproteinase · pentosidine · achilles tendinitis · article · biochemical composition · biopsy · clinical article · controlled study · cross linking · enzyme activity · gene expression · genetic analysis · human · human tissue · hydroxylation · laboratory test · nucleotide sequence · priority journal · turnover time · upregulation · water content · Achilles Tendon · Adult · Aged · Biomechanics · Collagen · Female · Gene Expression · Humans · Male · Matrix Metalloproteinase 3 · Middle Aged · Tendinopathy · Water
[Abstract]

18 MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis
article 2005    
Author: Tchetverikov, I. · Lohmander, L.S. · Verzijl, N. · Huizinga, T.W.J. · TeKoppele, J.M. · Hanemaaijer, R. · Groot, J. de
Keywords: Biomedical Research · alpha 2 macroglobulin · interstitial collagenase · matrix metalloproteinase · prointerstitial collagenase · prostromelysin · stromelysin · tissue inhibitor of metalloproteinase 3 · unclassified drug · arthritis · controlled study · enzyme activation · enzyme activity · enzyme inhibition · human · immunoassay · joint injury · knee · major clinical study · osteoarthritis · priority journal · protein determination · pseudogout · quantitative analysis · synovial fluid level · Acute Disease · Adult · alpha-Macroglobulins · Arthritis · Chondrocalcinosis · Cross-Sectional Studies · Female · Humans · Knee Injuries · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Synovial Fluid · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

19 A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease
article 2010    
Author: Eefting, D. · Seghers, L. · Grimbergen, J.M. · Vries, M.R. de · Boer, H.C. de · Lardenoye, J.W.H.P. · Jukema, J.W. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Health · Biomedical Research · Gene therapy · Matrix metalloproteinases · Plasmin(ogen) · Vascular surgery · Vein graft disease · apolipoprotein E3 · aprotinin · hybrid protein · matrix metalloproteinase · matrix metalloproteinase inhibitor · plasmin · plasmin inhibitor · plasminogen activator · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 1 amino terminal fragment of urokinase type plasminogen activator bovine pancreas trypsin inhibitor · unclassified drug · urokinase receptor · animal cell · animal experiment · animal model · animal tissue · article · carotid artery · cell surface · controlled study · electroporation · expression vector · female · gene overexpression · gene targeting · genetic transfection · human · human tissue · hypercholesterolemia · in vivo culture · intima · male · mouse · nonhuman · nonviral gene delivery system · priority journal · vein graft disease
[Abstract]

20 Determination of matrilysin activity in gastrointestinal neoplasia
article 2007    
Author: Hawinkels, L.J.A.C. · Verspaget, H.W. · Berg, M. van den · Hanemaaijer, R. · Sier, C.F.M.
Keywords: Biology · Biomedical Research · Controlled study · Digestive system cancer · Enzyme activity · Western blotting · Colorectal Neoplasms · Humans · Immunohistochemistry · Matrix Metalloproteinase 7 · Tumor Markers, Biological

Search results also available in MS Excel format.

Showing 1 to 20 of 74 found. Next | Sort by date