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1 Activity based protein profiling leads to identification of novel protein targets for nerve agent VX
article 2017    
Author: Carmany, D. · Walz, A.J. · Hsu, F.L. · Benton, B. · Burnett, D. · Gibbons, J. · Noort, D. · Glaros, T. · Sekowski, J.W.
Keywords: Acylglycerol lipase · Fatty acid amidase · Isocitrate dehydrogenase · Isocitrate dehydrogenase 2 · Isocitrate dehydrogenase 3 · Malate dehydrogenase · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Streptavidin · Succinate coenzyme A ligase · Unclassified drug · Animal tissue · Brain tissue · Cell lysate · Cholinergic system · Controlled study · Covalent bond · Eiaphragm · Energy metabolism · Enzyme inhibition · Heart tissue · Kidney tissue · Liquid chromatography-mass spectrometry · Liver tissue · Nonhuman · Protein interaction · Protein targeting · Quantitative analysis · Rat · Acylglycerol lipase, 9040-75-9 · Fatty acid amidase, 153301-19-0 · Isocitrate dehydrogenase, 9001-58-5 · Malate dehydrogenase, 9001-64-3 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Streptavidin, 9013-20-1 · Succinate coenzyme A ligase, 37341-57-4, 9014-36-2, 9080-33-5 · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

2 Verification of exposure to organophosphates: Generic mass spectrometric method for detection of human butyrylcholinesterase adducts
article 2006    
Author: Noort, D. · Fidder, A. · Schans, M.J. van der · Hulst, A.G.
Keywords: Enzyme inhibition · Ethanol · Mass spectrometry · Phosphates · Plasmas · Proteins · Generic mass spectrometric · Human butyrylcholinesterase adducts · Organophosphates · Phosphylated peptides · Biochemistry · Cholinesterase · Cholinesterase inhibitor · Dichlorvos · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Nerve gas · Nonapeptide · Organophosphate pesticide · Organophosphorus compound · Pepsin A · Phosphoserine · Procainamide · Proton · Sarin · Soman · Analytic method · Article · Biological monitoring · Chemical warfare · Cholinesterase inhibition · Human · Liquid chromatography · Plasma · Solid phase extraction · Spectrometer · Tandem mass spectrometry · Terrorism · Time of flight mass spectrometry · Butyrylcholinesterase · Chromatography, Liquid · Humans · Phosphoric Acid Esters · Solid Phase Extraction · Tandem Mass Spectrometry
[Abstract]

3 Capillary gas chromatographic analysis of nerve agents using large volume injections
article 1996    
Author: Degenhardt, C.E.A.M. · Kientz, C.E.
Keywords: Biology · GC - Gas chromatography · Nerve agents · Capillarity · Phosphorus organic compounds · GB agent · Military chemical agents · Cholinesterase Inhibitors · Isoflurophate, 55-91-4 · Organophosphorus compounds · Organothiophosphorus compounds · Sarin, 107-44-8 · Soman, 96-64-0 · VX, 50782-69-9 · Water, 7732-18-5 · Chemical warfare agents · DFP · Large volume injection · Organophosphorus compounds · Tabun · Dflos · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Capillary gas chromatography · Drug determination · Nonhuman · Sample · Technique · Water analysis · Water pollution · Cholinesterase Inhibitors · Chromatography, Gas · Hydrogen-Ion Concentration
[Abstract]

4 Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication
article 2002    
Author: Bueters, T.J.H. · Groen, B. · Danhof, M. · IJzerman, A.P. · Helden, H.P.M. van
Keywords: Biology · Acetylcholine release · Adenosine A1 receptor · N6-Cyclopentyladenosine · Organophosphate · Adenosine A1 receptor agonist · Adenosine receptor stimulating agent · Cyclohexyladenosine · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Adenosine receptor · Cholinesterase · Drug derivative · N(6) cyclopentyladenosine · Organophosphate · Phosphorothioic acid derivative · Bioaccumulation · Cholinergic system · Concentration response · Controlled study · Corpus striatum · Crug efficacy · Enzyme activity · Hippocampus · Intoxication · Male · Microdialysis · Nonhuman · Rat · Reduction · Animal · Drug potentiation · Enzymology · Metabolism · Secretion · Wistar rat · Animals · Cholinesterase Inhibitors · Cholinesterases · Corpus Striatum · Male · Microdialysis · Organothiophosphorus Compounds · Parathion · Phosphoric Acid Esters · Rats · Rats, Wistar · Receptors, Purinergic P1 · Sarin · Acetylcholinesterase, 9000-81-1 · Cyclohexyladenosine, 36396-99-3 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Parathion, 3270-86-8, 56-38-2, 597-88-6 · Sarin, 107-44-8; tabun, 77-81-6 · Acetylcholine, 51-84-3 · Adenosine, 58-61-7; · Cholinesterase Inhibitors · Cholinesterases, EC 3.1.1.8 · N(6)-cyclopentyladenosine, 41552-82-3 · Organothiophosphorus Compounds · Parathion, 56-38- · Phosphoric Acid Esters · Receptors, Purinergic P1 · Sarin, 107-44-8 · Tabun, 77-81-6 · VX, 50782-69-9
[Abstract]

5 Toxicokinetics of the nerve agent (±)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration
article 2003    
Author: Schans, M.J. van der · Lander, B.J. · Wiel, H. van der · Langenberg, J.P. · Benschop, H.P.
Keywords: Biology · Chiral HPLC · Hairless guinea pigs · Intravenous · Marmosets · Percutaneous · Persistence · Stereospecificity · Toxicokinetics · Treatment · Carbamic acid · Oxime · Volatile agent · Anesthesia · Animal experiment · Animal model · Bioavailability · Blood level · Dose response · Enantiomer · Guinea pig · Intoxication · Marmoset · Nonhuman · Primate · Toxicokinetics · Administration, Topical · Anesthesia · Animals · Atropine · Callithrix · Chemical Warfare Agents · Chromatography, Gas · Chromatography, High Pressure Liquid · Electrochemistry · Injections, Intravenous · Kinetics · Lethal Dose 50 · Male · Muscarinic Antagonists · Organothiophosphorus Compounds · Stereoisomerism · Animalia · Cavia · Cavia porcellus · Primates · Sus scrofa · Acetylcholinesterase, 9000-81-1 · Carbamic acid, 463-77-4 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Sarin, 107-44-8 · Soman, 96-64-0 · Acetylcholinesterase, EC 3.1.1.7 · Atropine, 51-55-8 · Chemical warfare agents · Muscarinic antagonists · Organothiophosphorus compounds · VX, 50782-69-9
[Abstract]

Search results also available in MS Excel format.

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