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1 Apolipoprotein CI stimulates the response to lipopolysaccharide and reduces mortality in gram-negative sepsis.
article 2006    
Author: Berbée, J.F. · Hoogt, C.C. van der · Kleemann, R. · Schippers, E.F. · Kitchens, R.L. · Dissel, J.T. van · Bakker-Woudenberg, I.A. · Havekes, L.M. · Rensen, P.C.
Keywords: Biology · Drug effect · Gram negative bacterium · Immunology · Mortality · Mouse · Mouse mutant · Nucleotide sequence · Transgenic mouse · Animals · Antigen Presentation · Apolipoprotein C-I · Apolipoproteins C · Binding Sites · Conserved Sequence · Gram-Negative Bacteria · Humans · Immunity · Inflammation · Lipopolysaccharides · Macrophages · Mice · Mice, Knockout · Mice, Transgenic · Sepsis
[Abstract]

2 RPLC-lon-trap-FTMS method for lipid profiling of plasma: Method validation And application to p53 mutant mouse model
article 2008    
Author: Hu, C. · Dommelen, J. van · Heijden, R. van der · Spijksma, G. · Reijmers, T.H. · Wang, M. · Slee, E. · Lu, X. · Xu, G. · Greef, J. van der · Hankemeier, T.
Keywords: Analytical research · FTMS · Lipid profiling · Lipidomics · Metabolite profiling · Metabolomics · P53 mouse model · Protein p53 · Lipid · Article · Controlled study · High performance liquid chromatography · Human · Ion cyclotron resonance mass spectrometry · Ion trap mass spectrometry · Lipid analysis · Lipid blood level · Mouse · Mutational analysis · Nonhuman · Phenotype · Priority journal · Protein expression · Reversed phase liquid chromatography · Animal · Blood · Cyclotron · Infrared spectroscopy · Liquid chromatography · Methodology · Mouse mutant · Reproducibility · Tandem mass spectrometry · Mus · Animals · Chromatography, Liquid · Cyclotrons · Lipids · Mice · Mice, Mutant Strains · Reproducibility of Results · Spectroscopy, Fourier Transform Infrared · Tandem Mass Spectrometry · Tumor Suppressor Protein p53
[Abstract]

3 Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor γ function (P465L PPARγ) in mice
article 2006    
Author: Gray, S.L. · Dalla Nora, E. · Grosse, J. · Manieri, M. · Stoeger, T. · Medina-Gomez, G. · Burling, K. · Wattler, S. · Russ, A. · Yeo, G.S.H. · Chatterjee, V.K. · O'Rahilly, S. · Voshol, P.J. · Cinti, S. · Vidal-Puig, A.
Keywords: Biology · Peroxisome proliferator activated receptor gamma · Adipose tissue · Animal cell · Animal experiment · Animal model · Animal tissue · Carbohydrate metabolism · Controlled study · Energy balance · Female · Gene expression · gene mutation · Homozygosity · Hyperphagia · Insulin resistance · Insulin sensitivity · Lipid metabolism · Lipid storage · Lipogenesis · Male · Metabolic disorder · Nonhuman · Obesity · Point mutation · Protein deficiency · Protein function · Tissue distribution · Tissue expansion · Blood · Genetics · Glucose blood level · Homozygote · Lethal gene · Metabolism · Mouse mutant · Pathology · Physiology · Adipose Tissue · Animals · Blood Glucose · Gene Expression Profiling · Genes, Lethal · Homozygote · Insulin · Insulin Resistance · Leptin · Lipid Metabolism · Mice · Mice, Obese · PPAR gamma
[Abstract]

4 ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression
article 2005    
Author: Gerritsen, G. · Rensen, P.C.N. · Kypreos, K.E. · Zannis, V.I. · Havekes, L.M. · Dijk, K.W. van
Keywords: Biology · Biomedical Research · Adenovirus-mediated gene transfer · Lipoprotein lipase-mediated triglyceride hydrolysis · Mice · Very low density lipoprotein · Cholesterol · Fatty acid · Intermediate density lipoprotein · Lipoprotein · Triacylglycerol · Lipid · Lipoprotein lipase · Animal experiment · Animal tissue · Cholesterol blood level · Controlled study · Dose response · Emulsion · Female · Gene dosage · Gene overexpression · Hydrolysis · Hyperlipidemia · In vitro study · In vivo study · Injection · Lipoprotein deficiency · Mouse · Nonhuman · Protein blood level · White adipose tissue · Animal · Biosynthesis · Blood · Genetic transfection · Genetics · Metabolism · Mouse mutant · Animals · Apolipoprotein C-III · Apolipoprotein E4 · Apolipoproteins C · Apolipoproteins E · Humans · Hyperlipidemias · Lipids · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Mice · Mice, Knockout · Transfection · Triglycerides
[PDF] [Abstract]

5 Cholesterol 7α-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol
article 2006    
Author: Post, S.M. · Groenendijk, M. · Hoogt, C.C. van der · Fievet, C. · Luc, G. · Hoekstra, M. · Princen, H.M.G. · Staels, B. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · High-density lipoprotein · ABC transporter A1 · High density lipoprotein cholesterol · Intermediate density lipoprotein · Low density lipoprotein · Messenger RNA · Phosphatidylcholine sterol acyltransferase · Very low density lipoprotein · Bile acid · Phospholipid transfer protein · Phospholipid transfer protein, mouse · Animal experiment · Animal tissue · Bile acid synthesis · Biosynthesis · Catabolism · Cholesterol blood level · Cholesterol metabolism · cholesterol transport · Conhuman · Protein expression · Transgenic mouse · Genetics · Metabolism · Mouse · Mouse mutant · Physiology · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol, HDL · Female · Gene Expression Regulation · Gene Expression Regulation, Enzymologic · Humans · Liver · Mice · Mice, Knockout · Mice, Transgenic · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipid Transfer Proteins · RNA, Messenger
[Abstract]

6 Intrauterine exposure to maternal atherosclerotic risk factors increases the susceptibility to atherosclerosis in adult life
article 2007    
Author: Alkemade, F.E. · Gittenberger-Groot, A.C. de · Schiel, A.E. · Munsteren, J.C. van · Hogers, B. · Vliet, L.S.J. van · Poelmann, R.E. · Havekes, L.M. · Dijk, K.W. van · Ruiter, M.C. de
Keywords: Health · Biomedical Research · Atherosclerosis · Carotid arteries · Hypercholesterolemia · Pregnancy · Risk factors · apolipoprotein E · cholesterol · triacylglycerol · atherosclerosis · cardiovascular risk · carotid artery · cell volume · comparative study · controlled study · disease predisposition · endothelium cell · epigenetics · female · heterozygosity · hypercholesterolemia · hyperlipoproteinemia type 3 · intima · maternal disease · mother · mouse · nonhuman · prenatal development · prenatal exposure · progeny · risk factor · statistical significance · wild type · animal · blood · C57BL mouse · carotid artery injury · cell size · disease course · disease model · fetus blood · genetic epigenesis · genetics · genome imprinting · hospitalization · human · magnetic resonance angiography · metabolism · mouse mutant · pathology · pregnancy · transgenic mouse · Animals · Apolipoproteins E · Atherosclerosis · Carotid Arteries · Carotid Artery Injuries · Cell Size · Cholesterol · Disease Models, Animal · Disease Progression · Endothelial Cells · Epigenesis, Genetic · Female · Fetal Blood · Genomic Imprinting · Humans · Hypercholesterolemia · Magnetic Resonance Angiography · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Pregnancy · Prenatal Exposure Delayed Effects · Risk Factors · Severity of Illness Index · Triglycerides · Tunica Intima
[ABSTRACT] [Abstract]

7 The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI
article 2008    
Author: Hu, L. · Hoogt, C.C. van der · Espirito Santo, S.M.S. · Out, R. · Kypreos, K.E. · Vlijmen, B.J.M. van · Berkel, T.J.C. van · Romijn, J.A. · Havekes, L.M. · Dijk, K.W. van · Rensen, P.C.N.
Keywords: Biology · Apolipoprotein · Denovirus-mediated gene transfer · Lipoprotein lipase · Low density lipoprotein receptor · Low density lipoprotein receptor-related protein · Transgenic mice · Triglyceride-rich emulsion particles · Very low density lipoprotein receptor · apolipoprotein E · cell surface protein · cholesterol · lipoprotein lipase · low density lipoprotein receptor · low density lipoprotein receptor related protein · proteoglycan · proteoheparan sulfate · scavenger receptor BI · triacylglycerol · very low density lipoprotein · very low density lipoprotein receptor · CD36 antigen · ligand · very low density lipoprotein cholesterol · Adenovirus · animal cell · animal experiment · animal tissue · article · cell isolation · cell surface · controlled study · enzyme activity · in vitro study · in vivo study · internalization · lipid analysis · liver cell · male · mouse · nonhuman · priority journal · protein expression · regulatory mechanism · animal · blood · emulsion · genetics · liver · metabolism · mouse mutant · Animals · Antigens, CD36 · Cholesterol, VLDL · Emulsions · LDL-Receptor Related Proteins · Ligands · Lipoprotein Lipase · Liver · Male · Mice · Mice, Knockout · Proteoglycans · Receptors, LDL · Healthy for Life · Healthy Living
[Abstract]

8 ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency
article 2008    
Author: Gerritsen, G. · Hoogt, C.C. van der · Schaap, F.G. · Voshol, P.J. · Kypreos, K.E. · Maeda, N. · Groen, A.K. · Havekes, L.M. · Rensen, P.C.N. · Dijk, K.W. van
Keywords: Health · Physiological Sciences · Adenovirus-mediated gene transfer · APOE2-knockin mice · Apolipoprotein A-V · Apolipoprotein C-III · Apolipoprotein E2 · Lipoprotein lipase-mediated very low density lipoprotein-triglyceride hydrolysis · apolipoprotein A · apolipoprotein A5 · apolipoprotein B · apolipoprotein C · apolipoprotein C3 · apolipoprotein D · apolipoprotein E · apolipoprotein M · beta2 glycoprotein 1 · clusterin · heparin · Apoa5 protein, mouse · apolipoprotein · Adenovirus · animal experiment · animal model · cholesterol blood level · conference paper · controlled study · disease association · female · gene overexpression · hypertriglyceridemia · in vivo study · lipoprotein deficiency · mouse · nonhuman · stimulation · triacylglycerol blood level · animal · blood · gene transfer · genetics · mouse mutant · physiology · Adenoviridae · Animals · Apolipoprotein C-III · Apolipoprotein E2 · Apolipoproteins · Gene Transfer Techniques · Hypertriglyceridemia · Lipids · Lipoprotein Lipase · Male · Mice · Mice, Knockout
[PDF] [Abstract]

9 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

10 αB-Crystallin-reactive T cells from knockout mice are not encephalitogenic
article 2006    
Author: Wang, C. · Chou, Y.K. · Rich, C.M. · Link, J.M. · Afentoulis, M.E. · Noort, J.M. van · Wawrousek, E.F. · Offner, H. · Bark, A.A. van den
Keywords: EAE/MS · Knockout mice · T cells · Tolerance · Alpha B crystallin · Amino acid derivative · Crystallin · Cytokine · Encephalitogenic protein · Heat shock protein · Methionylglutamylvalylglycyltryptophyltyrosylarginylserylprolyl Phenylalanylserylarginylvalylvalylhistidylleucyltyrosylarginylasparaginylglycyl lysine · Unclassified drug · Alpha crystallin · Glycoprotein · Myelin oligodendrocyte glycoprotein (35 55) · Peptide fragment · Allergic encephalomyelitis · Animal cell · Animal experiment · Animal model · Animal tissue · CD4+ T lymphocyte · Cell line · Cell proliferation · Central nervous system · Controlled study · Cytokine release · Disease severity · Immunization · Immunocompetence · Immunological tolerance · Mouse · Multiple sclerosis · Nonhuman · Nucleotide sequence · Protein expression · Protein function · Th1 cell · Genetics · Lmmunology · Lymph node · Molecular genetics · Mouse mutant · Physiology · Reverse transcription polymerase chain reaction · Alpha-Crystallin B Chain · Amino Acid Sequence · Animals · Encephalomyelitis, Autoimmune, Experimental · Glycoproteins · Lymph Nodes · Lymphocyte Activation · Mice · Mice, Knockout · Molecular Sequence Data · Peptide Fragments · Reverse Transcriptase Polymerase Chain Reaction · Spleen · T-Lymphocytes
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 10 of 10 found. | Sort by date