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1 Angiogenesis and anti-angiogenesis: Perspectives for the treatment of solid tumors
article 1999    
Author: Hinsbergh, V.W.M. van · Collen, A. · Koolwijk, P.
Keywords: Biology · Angiogenesis · Angiogenesis inhibition · Angiogenic growth factors · Endothelium · Matrix-degrading proteases · Pancreas · Humans · Neoplasms · Neovascularization, Pathologic · Pancreatic Neoplasms
[Abstract]

2 Unfractionated and low molecular weight heparin affect fibrin structure and angiogenesis in Vitro
article 2000    
Author: Collen, A. · Smorenburg, S.M. · Peters, E. · Lupu, F. · Koolwijk, P. · Noorden, C. van · Hinsbergh, V.W.M. van
Keywords: Cell Division · Dose-Response Relationship, Drug · Endothelium, Vascular · Fibrin · Fibrinolytic Agents · Heparin · Heparin, Low-Molecular-Weight · Humans · Neovascularization, Physiologic
[Abstract]

3 Angiogenesis: An improved in vitro biological system and automated image-based workflow to aid identification and characterization of angiogenesis and angiogenic modulators
article 2008    
Author: Santos, A.F. · Zaltsman, A.B. · Martin, R.C. · Kuzmin, A. · Alexandrov, Y. · Roquemore, E.P. · Jessop, R.A. · Erck, M.G.M.V. · Verheijen, J.H.
Keywords: angiogenesis modulator · bevacizumab · suramin · angiogenesis · article · automation · controlled study · human · human cell · image analysis · in vitro study · instrumentation · Angiogenesis Modulating Agents · Antibodies, Monoclonal · Automation · Cells, Cultured · Dose-Response Relationship, Drug · Drug Evaluation, Preclinical · Fibrinogen · Fluorescent Dyes · Humans · Image Processing, Computer-Assisted · Immunohistochemistry · Neovascularization, Pathologic · Neovascularization, Physiologic · Suramin · Tissue Fixation · Tumor Necrosis Factor-alpha · Vascular Endothelial Growth Factor A
[Abstract]

4 Insights into mechanisms behind arteriogenesis: What does the future hold?
article 2008    
Author: Oostrom, M.C. van · Oostrom, O. van · Quax, P.H.A. · Verhaar, M.C. · Hoefer, I.E.
Keywords: Cell therapy · Growth factors · growth factor · monocyte chemotactic protein 1 · vasculotropin · vasculotropin A · vasculotropin B · vasculotropin C · vasculotropin D · angiogenesis · blood flow · cell differentiation · cell therapy · cell type · clinical trial · human · neovascularization (pathology) · priority journal · review · Angiogenesis Inducing Agents · Arterial Occlusive Diseases · Collateral Circulation · Humans · Neovascularization, Physiologic
[Abstract]

5 Pericellular proteases in angiogenesis and vasculogenesis
article 2006    
Author: Hinsbergh, V.W.M. van · Engelse, M.A. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Cathepsins · Endothelium · MT-MMPs · Neovascularization · Aminopeptidase · Angiogenic factor · Cathepsin L · Cytokine · Gelatinase A · Gelatinase B · Hemostatic agent · Hermes antigen · Matrix metalloproteinase 14 · Matrix metalloproteinase inhibitor · Pericellular proteinase · Proteinase · Serine proteinase · Unclassified drug · Urokinase · Vitronectin receptor · Accessory cell · Angiogenesis · Antiangiogenic activity · Antigen binding · Blood cell · Bone marrow cell · Cell membrane · Cell migration · Cell survival · Endothelium cell · Enzyme activity · Enzyme localization · Enzyme substrate complex · Extracellular matrix · Focal adhesion · Lamellipodium · Nonhuman · Protein degradation · Receptor binding · Vascular endothelium · ADAM Proteins · Aminopeptidases · Animals · Bone Marrow Cells · Cathepsins · Cell Differentiation · Cell Movement · Extracellular Matrix · Extracellular Matrix Proteins · Humans · Matrix Metalloproteinases · Mice · Neovascularization, Pathologic · Neovascularization, Physiologic · Peptide Hydrolases · Pericytes · Serine Endopeptidases · Tissue Inhibitor of Metalloproteinases
[Abstract]

6 Critical role of tissue kallikrein in vessel formation and maturation : Implications for therapeutic revascularization
article 2009    
Author: Stone, O.A. · Richer, C. · Emanueli, C. · Weel, V. van · Quax, P.H.A. · Katare, R. · Kraenkel, N. · Campagnolo, P. · Barcelos, L.S. · Siragusa, M. · Sala-Newby, G.B. · Baldessari, D. · Mione, M. · Vincent, M.P. · Benest, A.V. · Al Haj Zen, A. · Gonzalez, J. · Bates, D.O. · Alhenc-Gelas, F. · Madeddu, P.
Keywords: Biology · Biomedical Research · Angiogenesis · Gene mutations · Gene therapy · Metalloproteinases · Animals · Hindlimb · Humans · Ischemia · Kallikrein-Kinin System · Male · Matrix Metalloproteinase 9 · Mice · Mice, Knockout · Neovascularization, Physiologic · Rats · Splanchnic Circulation · Tissue Kallikreins · Wound Healing · Zebrafish
[Abstract]

7 Aberrant fibrin formation and cross-linking of fibrinogen Nieuwegein, a variant with a shortened Aα-chain, alters endothelial capillary tube formation
article 2001    
Author: Collen, A. · Maas, A. · Kooistra, T. · Lupu, F. · Grimbergen, J. · Haas, F.J.L.M. · Biesma, D.H. · Koolwijk, P. · Koopman, J. · Hinsbergh, V.W.M. van
Keywords: Adult · Afibrinogenemia · Biopolymers · Capillaries · Cells, Cultured · Codon, Terminator · Endothelium, Vascular · Exons · Fibrin · Fibrinogens, Abnormal · Humans · Male · Microscopy, Electron · Molecular Weight · Mutagenesis, Insertional · Neovascularization, Physiologic · Oligopeptides · Partial Thromboplastin Time · Receptors, Vitronectin · Sequence Deletion · Structure-Activity Relationship · Transglutaminases
[Abstract]

8 CD34+ cells home, proliferate, and participate in capillary formation, and in combination with CD34- cells enhance tube formation in a 3-dimensional matrix
article 2005    
Author: Rookmaaker, M.B. · Verhaar, M.C. · Loomans, C.J.M. · Verloop, R. · Peters, E. · Westerweel, P.E. · Murohara, T. · Staal, F.J.T. · Zonneveld, A.J. van · Koolwijk, P. · Rabelink, T.J. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Angiogenesis · Gene therapy · Nitric oxide, endothelium, vascular type · CD34 antigen · Nitric oxide · Bone marrow cell · Capillary endothelium · Capillary proliferation · Cell population · Cell proliferation · Facilitation · Gene therapy · Hhematopoietic stem cell · Human cell · Immunohistochemistry · Marker gene · Neovascularization (pathology) · Nerve sprouting · Neural tube · Peripheral vascular disease · Antigens, CD34 · Biological Markers · Capillaries · Cell Differentiation · Cell Division · Cell Movement · Cell Separation · Cells, Cultured · Coculture Techniques · Endothelium, Vascular · Fetal Blood · Hematopoietic Stem Cells · Humans · Neovascularization, Physiologic
[Abstract]

9 Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix
article 2003    
Author: Collen, A. · Hanemaaijer, R. · Lupu, F. · Quax, P.H.A. · Lent, N. van · Grimbergen, J. · Peters, E. · Koolwijk, P. · Hinsbergh, V.W.M. van
Keywords: Biology · Biomedical Research · Adenoviridae · Aprotinin · Cells, Cultured · Collagen · Culture Media · Defective Viruses · Drug Synergism · Endothelial Growth Factors · Endothelium, Vascular · Fibrin · Fibroblast Growth Factor 2 · Genetic Vectors · Heart Diseases · Humans · Intercellular Signaling Peptides and Proteins · Lymphokines · Matrix Metalloproteinase 1 · Matrix Metalloproteinase 2 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Neovascularization, Pathologic · Neovascularization, Physiologic · Phenylalanine · Protease Inhibitors · Thiophenes · Thrombosis · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Transduction, Genetic · Tumor Necrosis Factor-alpha · Vascular Endothelial Growth Factor A · Vascular Endothelial Growth Factors
[Abstract]

10 Vascular Growth in Ischemic Limbs: A Review of Mechanisms and Possible Therapeutic Stimulation
article 2008    
Author: Weel, V. van · Tongeren, R.B. van · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Health · Biomedical Research · adenovirus vector · angiogenic factor · fibrin · fibroblast growth factor · fibroblast growth factor 4 · granulocyte macrophage colony stimulating factor · placebo · plasmid vector · protein · scatter factor · vasculotropin · vasculotropin 121 · vasculotropin 165 · vasculotropin A · vasculotropin C · angiogenesis · autologous bone marrow transplantation · bone marrow · Buerger disease · cell therapy · clinical trial · comprehension · coronary artery disease · diabetes mellitus · gene therapy · human · immune system · inflammatory cell · intermittent claudication · introspection · limb ischemia · neovascularization (pathology) · nonhuman · pain · peripheral occlusive artery disease · priority journal · review · stem cell · stenosis · stimulation · Angiogenesis Inducing Agents · Animals · Collateral Circulation · Gene Therapy · Humans · Ischemia · Leg · Neovascularization, Physiologic · Stem Cell Transplantation · Vascular Endothelial Growth Factor A
[Abstract]

11 Natural killer cells and CD4+ T-cells modulate collateral artery development
article 2007    
Author: Weel, V. van · Toes, R.E.M. · Seghers, L. · Deckers, M.M.L. · Vries, M.R. de · Eilers, P.H. · Sipkens, J. · Schepers, A. · Eefting, D. · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biomedical Research · Angiogenesis · Animal models of human disease · Peripheral vascular disease · biological marker · CD3 antigen · CD4 antigen · vascularization · Animals · Arterial Occlusive Diseases · CD4-Positive T-Lymphocytes · Collateral Circulation · Disease Models, Animal · Femoral Artery · Hindlimb · Ischemia · Killer Cells, Natural · Mice · Mice, Inbred BALB C · Mice, Knockout · Neovascularization, Physiologic
[Abstract]

12 TAFI and pancreatic carboxypeptidase B modulate in vitro capillary tube formation by human microvascular endothelial cells
article 2007    
Author: Guimarães, A.H.C. · Laurens, N. · Weijers, E.M. · Koolwijk, P. · Hinsbergh, V.W.M. van · Rijken, D.C.
Keywords: Biology · Biomedical Research · Angiogenesis · Carboxypeptidase B · Plasma clot matrix · Plasminogen · TAFI · Angiogenesis Inhibitors · Atherosclerosis · Capillaries · Carboxypeptidase B · Carboxypeptidase U · Cell Adhesion · Cell Culture Techniques · Cell Movement · Cell Proliferation · Cells, Cultured · Dose-Response Relationship, Drug · Endothelial Cells · Fibrin · Fibrin Fibrinogen Degradation Products · Fibroblast Growth Factor 2 · Humans · Neovascularization, Physiologic · Plant Proteins · Plasminogen · Protease Inhibitors · Time Factors · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator · Wound Healing
[PDF] [Abstract]

13 Effect of steroid hormones and retinoids on the formation of capillary-like tubular structures of human microvascular endothelial cells in fibrin matrices is related to urokinase expression
article 1998    
Author: Lansink, M. · Koolwijk, P. · Hinsbergh, V. van · Kooistra, T.
Keywords: Health · Aprotinin · Calcitriol · Capillaries · Cell Culture Techniques · Cells, Cultured · Drug Interactions · Endothelium, Vascular · Extracellular Matrix · Fibrin · Fibroblast Growth Factor 2 · Gene Expression Regulation · Gonadal Steroid Hormones · Humans · Male · Morphogenesis · Neovascularization, Physiologic · Plasmin · Polymerase Chain Reaction · Receptors, Cell Surface · Receptors, Retinoic Acid · Receptors, Steroid · Retinoids · RNA, Messenger · Steroids · Tissue Plasminogen Activator · Triiodothyronine · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

14 Nature and origin of the neointima in whole vessel wall organ culture of the human saphenous vein
article 1996    
Author: Slomp, J. · Gittenberger - Groot, A.C. de · Munsteren, J.C. van · Huysmans, H.A. · Bockel, J.H. van · Hinsbergh, V.W.M. van · Poelmann, R.E.
Keywords: Biology · Endothelial cells · Neointima formation · Organ culture · Smooth muscle cells · Acetyl low density lipoprotein · Cd31 antigen · Fluorescent dye · Monoclonal antibody · Von willebrand factor · Fibroblast · Fluorescence analysis · Human tissue · Intima · Major clinical study · Vascular endothelium · Vascular smooth muscle · Adult · Aged · Endothelium, Vascular · Female · Humans · Male · Middle Aged · Muscle, Smooth · Neovascularization, Physiologic · Organ Culture Techniques · Saphenous Vein · Tunica Intima
[Abstract]

15 Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients
article 2002    
Author: Kuenen, B.C. · Levi, M. · Meijers, J.C.M. · Kakkar, A.K. · Hinsbergh, V.W.M. van · Kostense, P.J. · Pinedo, H.M. · Hoekman, K.
Keywords: Angiogenesis Inhibitors · Blood Coagulation · Blood Platelets · Carcinoma, Renal Cell · Cell Division · Cell Membrane Permeability · Cell Movement · Drug Administration Schedule · Endothelium, Vascular · Fibrinolysis · Hemostasis · Indoles · Kidney Neoplasms · Melanoma · Neovascularization, Pathologic · Protein C · Proto-Oncogene Proteins · Pyrroles · Receptor Protein-Tyrosine Kinases · Receptors, Growth Factor · Receptors, Vascular Endothelial Growth Factor · Sarcoma · Thrombin · Vascular Endothelial Growth Factor Receptor-1
[Abstract]

16 Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro
article 2003    
Author: Nieuw Amerongen, G.P. van · Koolwijk, P. · Versteilen, A. · Hinsbergh, V.W.M. van
Keywords: Amides · Capillaries · Cell Culture Techniques · Cell Movement · Cells, Cultured · Cytoskeleton · Endothelial Growth Factors · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Fibrin · Humans · Intercellular Signaling Peptides and Proteins · Lymphokines · Male · Neovascularization, Physiologic · Penis · Pyridines · rho GTP-Binding Proteins · rhoA GTP-Binding Protein · Signal Transduction · Umbilical Veins · Vascular Endothelial Growth Factor A · Vascular Endothelial Growth Factors
[Abstract]

17 Proteolysis of the urokinase-type plasminogen activator receptor by metalloproteinase-12: Implication for angiogenesis in fibrin matrices
article 2001    
Author: Koolwijk, P. · Sidenius, N. · Peters, E. · Sier, C.F.M. · Hanemaaijer, R. · Blasi, F. · Hinsbergh, V.W.M. van
Keywords: Binding Sites · Blotting, Western · Cells, Cultured · Endothelium, Vascular · Fibrin · Fibroblast Growth Factor 2 · Gene Expression · Humans · Metalloendopeptidases · Microcirculation · Neovascularization, Physiologic · Phenylalanine · Protease Inhibitors · Receptors, Cell Surface · Recombinant Proteins · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Thiophenes · Transfection · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

18 Modulating angiogenesis: The yin and the yang in ginseng
article 2004    
Author: Sengupta, S. · Toh, S.A. · Sellers, L.A. · Skepper, J.N. · Koolwijk, P. · Leung, H.W. · Yeung, H.W. · Wong, R.N.S. · Sasisekharan, R. · Fan, T.P.D.
Keywords: Biology · Biomedical Research · Angiogenesis · Nitric oxide · ginseng extract · ginseng polysaccharide · herbaceous agent · nitric oxide synthase · Panax notoginseng extract · panax quinquefolium extract · phosphatidylinositol 3 kinase · polymer · protein kinase B · sterol derivative · animal experiment · animal model · antiangiogenic activity · cell invasion · cell proliferation · chemical analysis · chemical composition · controlled study · drug effect · drug identification · drug isolation · drug mechanism · drug screening · drug structure · endothelium cell · herbal medicine · human cell · human tissue · in vitro study · in vivo study · law · mass spectrometry · neovascularization (pathology) · nonhuman · phenotype · protein expression · regulatory mechanism · species differentiation · standardization · wound healing · 1-Phosphatidylinositol 3-Kinase · Americas · Angiogenesis Inducing Agents · Angiogenesis Inhibitors · Animals · Cells, Cultured · China · Drug Implants · Endothelial Cells · Endothelium, Vascular · Enzyme Inhibitors · Ginsenosides · Humans · Korea · Male · Mice · Mice, Inbred C57BL · Molecular Structure · Neovascularization, Pathologic · NG-Nitroarginine Methyl Ester · Panax · Phytotherapy · Signal Transduction · Species Specificity · Spectrometry, Mass, Electrospray Ionization · Surgical Sponges · Umbilical Veins
[Abstract]

19 Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis
article 2014    
Author: Lange-Brokaar, B.J.E. de · Ioan-Facsinay, A. · Yusuf, E. · Visser, A.W. · Kroon, H.M. · Andersen, S.N. · Herb-van Toorn, L. · Osch, G.J.V.M. van · Zuurmond, A.M. · Stojanovic-Susulic, V. · Bloem, J.L. · Nelissen, R.G.H.H. · Huizinga, T.W.J. · Kloppenburg, M.
Keywords: Biology · Macroscopy · MRI · Osteoarthritis · Synovial tissue · Synovitis · Gadolinium · Adult · Clinical article · Correlational study · Female · Fibrin deposition · Histology tissue · Hyperplasia · Joint biopsy · Kellgren Lawrence scale · Knee arthroplasty · Knee arthroscopy · Knee osteoarthritis · Male · Microscopy · Named inventories, questionnaires and rating scales · Neovascularization (pathology) · Nuclear magnetic resonance imaging · Nuclear magnetic resonance scanner · Observational study · Outcome assessment · Pain severity · Radiological parameters · Synovitis · Synovium · Visual analog scale · X ray film · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

20 Differential gene expression analysis of tubule forming and non-tubule forming endothelial cells: CDC42GAP as a counter-regulator in tubule formation
article 2008    
Author: Engelse, M.A. · Laurens, N. · Verloop, R.E. · Koolwijk, P. · Hinsbergh, V.W.M. van
Keywords: Angiogenesis · CDC42GAP · Differential gene expression · Fibrin matrix · Microdissection · basic fibroblast growth factor · cdc42gap protein · complementary DNA · messenger RNA · protein derivative · small interfering RNA · tumor necrosis factor alpha · vasculotropin · angiogenesis · article · cell population · controlled study · endothelium cell · human · human cell · human cell culture · microdissection · phenotype · priority journal · protein expression · real time polymerase chain reaction · RNA extraction · Biological Assay · Biological Markers · Cell Movement · Cells, Cultured · Endothelial Cells · Endothelium, Vascular · Gene Expression Profiling · GTPase-Activating Proteins · Humans · Lasers · Microdissection · Neovascularization, Physiologic · Phosphoproteins
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 28 found. Next | Sort by date