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1 Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice
article 2007    
Author: Hoorn, J.W.A. van der · Kleemann, R. · Havekes, L.M. · Kooistra, T. · Princen, H.M.G. · Jukema, J.W.
Keywords: Biology · Biomedical Research · APOE*3Leiden mice · Atherosclerosis · Combination therapy · Olmesartan · Pravastatin · T lymphocyte · transgenic mouse · Angiotensin II Type 1 Receptor Blockers · Animals · Apolipoprotein E3 · Atherosclerosis · Blood Pressure · Collagen · Diet, Atherogenic · Drug Synergism · Female · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Imidazoles · Inflammation · Lipids · Macrophages · Mice · Mice, Transgenic · Monocytes · Muscle, Smooth, Vascular · Pravastatin · Recombinant Proteins · Serum Amyloid A Protein · T-Lymphocytes · Tetrazoles
[PDF] [Abstract]

2 Mouse models for atherosclerosis and pharmaceutical modifiers
article 2007    
Author: Zadelaar, A.S.M. · Kleemann, R. · Verschuren, L. · Vries-van der Weij, J. de · Hoorn, J. van der · Princen, H.M. · Kooistra, T.
Keywords: Biology · Biomedical Research · ACE inhibitors · AT1 receptor antagonists · Atherosclerosis · LXR · Mouse models · Pharmaceutical drugs · PPAR · Statins · atorvastatin · avasimibe · candesartan · captopril · cholesterol acyltransferase inhibitor · dipeptidyl carboxypeptidase inhibitor · hydralazine · hydroxymethylglutaryl coenzyme A reductase inhibitor · irbesartan · losartan · ly 465608 · n (2,2,2 trifluoroethyl) n [4 [2,2,2 trifluoro 1 hydroxy 1 (trifluoromethoxy)ethyl]phenyl]benzenesulfonamide · olmesartan · perindopril · peroxisome proliferator activated receptor alpha agonist · pirinixic acid · pitavastatin · pravastatin · quinapril · ramipril · rosuvastatin · simvastatin · telmisartan · temocapril · unindexed drug · valsartan · zofenopril · antihypertensive agent · antilipemic agent · apolipoprotein E · atherosclerosis · pathophysiology · sensitivity and specificity · Animals · Antihypertensive Agents · Antilipemic Agents · Apolipoproteins E · Atherosclerosis · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Dyslipidemias · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypertension · Male · Mice · Mice, Knockout · Mice, Transgenic · Sensitivity and Specificity
[Abstract]

3 Generation of Bayesian prediction models for OATP-mediated drug-drug interactions based on inhibition screen of OATP1B1, OATP1B1∗15 and OATP1B3
article 2015    
Author: Steeg, E. van de · Venhorst, J. · Jansen, H.T. · Nooijen, I.H.G. · Degroot, J. · Wortelboer, H.M. · Vlaming, M.L.H.
Keywords: Biology · Bayesian prediction model · Computational modeling · Drugdrug interaction · OATP · Polymorphisms · Transporter · Abamectin · Acemetacin · Atazanavir · Bromocriptine mesilate · Clarithromycin · Clobetasol propionate · Dihydroergocristine methanesulfonate · Dipyridamole · Docetaxel · Estradiol · Fluindostatin · Fosinopril · Losartan · Mifepristone · Nicardipine · Olmesartan · Pranlukast · Pyrantel embonate · Rapamycin · Rifampicin · Rifamycin · Salazosulfapyridine · Solute carrier organic anion transporter 1B1 · Solute carrier organic anion transporter 1B1 15 · Solute carrier organic anion transporter 1B3 · Suramin · Telmisartan · Tibolone · Troglitazone · Unclassified drug · Unindexed drug · Bayesian learning · Controlled study · Drug protein binding · HEK293 cell line · Human cell · Nucleotide sequence · Prediction · Priority journal · Protein expression · Tandem mass spectrometry · Ultra performance liquid chromatography · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

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