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1 Percutaneous exposure to the nerve agent VX: Efficacy of combined atropine, obidoxime and diazepam treatment
article 2010    
Author: Joosen, M.J.A. · Schans, M.J. van der · Helden, H.P.M. van
Keywords: Health · EEG · Organophosphate · Percutaneous · Physiology · Treatment · VX
[Abstract]

2 Levels of metabolites of organophosphate pesticides, phthalates, and bisphenol A in pooled urine specimens from pregnant women participating in the Norwegian Mother and Child Cohort Study (MoBa)
article 2009    
Author: Ye, X. · Pierik, F.H. · Angerer, J. · Meltzer, H.M. · Jaddoe, V.W.V. · Tiemeier, H. · Hoppin, J.A. · Longnecker, M.P.
Keywords: Health · Biological monitoring · Bisphenol A (BPA) · Environmental exposure · Organophosphate (OP) pesticides · Phthalates
[Abstract]

3 Treatment efficacy in a soman-poisoned guinea pig model: Added value of physostigmine?
article 2011    
Author: Joosen, M.J.A. · Smit, A.B. · Helden, H.P.M. van
Keywords: Chemistry · Obidoxime · Organophosphate · Physostigmine · Seizures · Soman · Life · CBRN - CBRN Protection · EELS - Earth, Environmental and Life Sciences
[Abstract]

4 Organophosphate Pesticide Metabolite Concentrations in Urine during Pregnancy and Offspring offspring attention-deficit hyperactivity disorder and autistic traits
article 2019    
Author: Dries, M.A. van den · Guxens, M. · Pronk, A. · Spaan, S. · Marroun, H. El · Jusko, T.A. · Longnecker, M.P. · Ferguson, K.K. · Tiemeier, H.
Keywords: Attention-deficit hyperactivity disorder · Autism spectrum disorder · Biomarkers · Organophosphate pesticides · Population-based birth cohort · Prenatal exposure
[PDF] [Abstract]

5 Fast temperature programming in gas chromatography using resistive heating
article 1999    
Author: Dallüge, J. · Ou-Aissa, R. · Vreuls, J.J. · Brinkman, U.A.T. · Veraart, J.R.
Keywords: alkane · organophosphate insecticide · polycyclic aromatic hydrocarbon derivative · triazine derivative · analytic method · article · gas chromatography · heating · reaction analysis · screening test
[Abstract]

6 The impact of skin decontamination on the time window for effective treatment of percutaneous VX exposure
article 2017    
Author: Joosen, M.J.A. · Berg, R.M. van den · Jong, A.L. de · Schans, M.J. van der · Noort, D. · Langenberg, J.P.
Keywords: Nerve agent · Organophosphate · Percutaneous · Skin decontamination · Treatment · VX · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

7 Data correlation in on-line solid-phase extraction-gas chromatography-atomic emission/mass spectrometric detection of unknown microcontaminants
article 1998    
Author: Hankemeier, Th. · Rozenbrand, J. · Abhadur, M. · Vreuls, J.J. · Brinkman, U.A.Th.
Keywords: Nutrition · Aqueous samples · Atomic emission and MS detection · Gas chromatography · Solid-phase extraction · Dimpylate · Ethion · Fenclofos · Organophosphate · Organophosphate pesticide · Phosphoric acid tris(2 chloroethyl) ester · Stirofos · Tap water · Triazophos · Atomic emission spectrometry · Calibration · Drug identification · Gas chromatography · Mass spectrometry · Priority journal · Solid phase extraction · Technique · Waste water · Water analysis · Water contamination
[Abstract]

8 Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R Study
article 2015    
Author: Spaan, S. · Pronk, A. · Koch, H.M. · Jusko, T.A. · Jaddoe, V.M.W. · Shaw, P.A. · Tiemeier, H.M. · Hofman, A. · Pierik F.H. · Longnecker M.P.
Keywords: Nutrition · Organophosphate pesticide metabolites · Environmental exposure · Variability; reliability · Cohort study · Epidemiologic studies · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

9 Quantitation of ortho-cresyl phosphate adducts to butyrylcholinesterase in human serum by immunomagnetic-UHPLC-MS/MS
article 2015    
Author: Johnson, D. · Carter, M.D. · Crow, B.S. · Isenberg, S.L. · Graham, L.A. · Erol, H.A. · Watson, C.M. · Pantazides, B.G. · Schans, M.J. van der · Langenberg, J.P. · Noort, D. · Blake, T.A. · Thomas, J.D. · Johnson, R.C.
Keywords: Butyrylcholinesterase · Dresyl saligenin phosphate · Jamaica ginger paralysis · Organophosphate-induced delayed neuropathy · Tri-ortho-cresyl-phosphate · Body fluids · Cabins (aircraft) · Calibration · Enzymes · Lubricants · Tribology · Butyrylcholinesterase · Esterase enzymes · Flame-retardant additives · Human exposures · Industrial lubricants · Jamaica · Neurotoxic effects · Organophosphate-induced delayed neuropathy · Cockpits (aircraft) · Cholinesterase · Tri ortho cresyl phosphate · Accuracy · Cholinesterase blood level · Controlled study · In vitro study · Limit of detection · Tandem mass spectrometry · Ultra performance liquid chromatography · Zingiber officinale · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

10 Therapy of organophosphate poisoning in the rat by direct effects of oximes unrelated to ChE reactivation
article 1991    
Author: Helden, H.P.M. van · Lange, J. de · Busker, R.W. · Melchers, B.P.C.
Keywords: Biology · Acetylcholinesterase · Direct effect · HGG-12 · HI-6 · Obidoxime · Organophosphate poisoning · P2S · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · [(3 benzoyl 1 pyridiniomethyl) (2 hydroxyiminomethyl 1 pyridiniomethyl)] ether · Obidoxime · Organophosphate · Oxime · Soman · Animal experiment · Animal tissue · Diaphragm · Enzyme inhibition · Enzyme reactivation · Intravenous drug administration · Male · Nonhuman · Priority journal · Rat · Animal · Antidotes · Blood-Brain Barrier · Cholinesterase Reactivators · Diaphragm · In Vitro · Male · Neuromuscular Junction · Obidoxime Chloride · Organophosphorus Compounds · Oximes · Pralidoxime Compounds · Pyridinium Compounds · Rats · Respiratory Insufficiency · Synaptic Transmission · Animalia
[Abstract]

11 Comprehensive gas chromatography with Time of Flight MS and large volume introduction for the detection of fluoride-induced regenerated nerve agent in biological samples
article 2010    
Author: Meer, J.A. van der · Trap, H.C. · Noort, D. · Schans, M.J. van der
Keywords: Defence · Comprehensive GC · Time of Flight MS · Nerve agents · Fluoride reactivation · Diagnosis · Chemicals/CAS: · Fluoride, 16984-48-8 · Sarin, 107-44-8 · Tabun, 77-81-6 · Chemical warfare agents · Cholinesterase inhibitors · Fluorides · Organophosphorus compounds · Phosphoric acid esters · Organophosphate · Organophosphorus compound · Blood · Chemistry · Human · Mass fragmentography · Methodology · Reproducibility · Sensitivity and specificity · Statistical model · Gas Chromatography-Mass Spectrometry · Linear models
[Abstract]

12 Activity-based protein profiling reveals broad activity of the nerve agent sarin
article 2009    
Author: Tuin, A.W. · Mol, M.A.E. · Berg, R.M. van den · Fidder, A. · Marel, G.A. van der · Overkleeft, H.S. · Noort, D.
Keywords: Chemistry · 1 alkyl 2 acetylglycerophosphocholine esterase · Acylamino acid releasing enzyme · Carboxylesterase · Dipeptidyl peptidase · Dipeptidyl peptidase 9 · Fatty acid synthase · Methylphosphonofluoridic acid · Organophosphate · Palmitoyl coenzyme A hydrolase · Prolyl endopeptidase · Sarin · Unclassified drug · Animal cell · Biotinylation · Chemical structure · Controlled study · Human · Human cell · Matrix assisted laser desorption ionization time of flight mass spectrometry · Nonhuman · Protein analysis · Quantitative analysis · Sensitivity analysis · Macaca mulatta
[Abstract]

13 A comparison of the oximes HS-6 and HI-6 in the therapy of soman intoxication in rodents
article 1978    
Author: Kepner, L.A. · Wolthuis, O.L.
Keywords: Biology · Atropine · Cholinesterase reactivator · Oxime · Soman · 1 (3 carbamoylpyridinio) 1 (2 hydroximinoethylpyridinio)dimethyl ether · Animal experiment · Breathing · Drug comparison · Drug intoxication · Drug response · Intoxication · Intraperitoneal drug administration · Mouse · Muscle · Musculoskeletal system · Neuromuscular transmission · Organophosphate poisoning · Rat · Respiratory system · Subcutaneous drug administration · Animal · Atropine · Comparative Study · Drug Synergism · Female · Male · Mice · Neuromuscular Junction · Organophosphorus Compounds · Oximes · Rats · Rats, Inbred Strains · Respiration · Soman
[Abstract]

14 Verification of exposure to organophosphates: Generic mass spectrometric method for detection of human butyrylcholinesterase adducts
article 2006    
Author: Noort, D. · Fidder, A. · Schans, M.J. van der · Hulst, A.G.
Keywords: Enzyme inhibition · Ethanol · Mass spectrometry · Phosphates · Plasmas · Proteins · Generic mass spectrometric · Human butyrylcholinesterase adducts · Organophosphates · Phosphylated peptides · Biochemistry · Cholinesterase · Cholinesterase inhibitor · Dichlorvos · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Nerve gas · Nonapeptide · Organophosphate pesticide · Organophosphorus compound · Pepsin A · Phosphoserine · Procainamide · Proton · Sarin · Soman · Analytic method · Article · Biological monitoring · Chemical warfare · Cholinesterase inhibition · Human · Liquid chromatography · Plasma · Solid phase extraction · Spectrometer · Tandem mass spectrometry · Terrorism · Time of flight mass spectrometry · Butyrylcholinesterase · Chromatography, Liquid · Humans · Phosphoric Acid Esters · Solid Phase Extraction · Tandem Mass Spectrometry
[Abstract]

15 Determination of polar organophosphorus pesticides in vegetables and fruits using liquid chromatography with tandem mass spectrometry: Selection of extraction solvent
article 2003    
Author: Mol, H.G.J. · Dam, R.C.J. van · Steijger, O.M.
Keywords: Packaging · Analytical research · Acephate · Fruits · Methamidophos · Monocrotophos · Omethoate · Organophosphorus compounds · Oxydemeton-methyl · Pesticides · Vamidothion · Vegetables · Fruits · Ionization · Mass spectrometry · Pesticides · Solvent extraction · Extraction efficiency · Liquid chromatography · acephate · acetic acid ethyl ester · methamidophos · monocrotophos · omethoate · organophosphate pesticide · oxydemeton methyl · solvent · unclassified drug · vamidothion · water · cabbage · conference paper · evaporation · extraction · fruit · grape · ionization · liquid chromatography · priority journal · spectrometer · tandem mass spectrometry · validation process · vegetable · Chromatography, High Pressure Liquid · Fruit · Insecticides · Mass Spectrometry · Organophosphorus Compounds · Reproducibility of Results · Vegetables · Brassica oleracea var. capitata · Vitaceae
[Abstract]

16 Long-term cognitive deficits accompanied by reduced neurogenesis after soman poisoning
article 2009    
Author: Joosen, M.J.A. · Jousma, E. · Boom, T.M. van den · Kuijpers, W.C. · Smit, A.B. · Lucassen, P.J. · Helden, H.P.M. van
Keywords: Toxicology · Learning · Memory · Neurogenesis · Olanzapine · Organophosphate · Soman · acetylcholine · acetylcholinesterase · atropine · doublecortin · olanzapine · soman · animal experiment · animal model · animal tissue · article · body weight · cell survival · cognitive defect · controlled study · corpus striatum · developmental disorder · drug efficacy · drug treatment failure · histopathology · learning disorder · male · maze test · memory disorder · nervous system development · neurotoxicity · nonhuman · osmotic minipump · priority journal · rat · recurrent disease · seizure · Acetylcholine · Acetylcholinesterase · Animals · Atropine · Benzodiazepines · Cholinesterase Reactivators · Corpus Striatum · Hippocampus · Male · Maze Learning · Neurogenesis · Pyridinium Compounds · Rats · Rats, Sprague-Dawley · Seizures · Soman · Animalia · Rattus
[Abstract]

17 Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication
article 2002    
Author: Bueters, T.J.H. · Groen, B. · Danhof, M. · IJzerman, A.P. · Helden, H.P.M. van
Keywords: Biology · Acetylcholine release · Adenosine A1 receptor · N6-Cyclopentyladenosine · Organophosphate · Adenosine A1 receptor agonist · Adenosine receptor stimulating agent · Cyclohexyladenosine · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Adenosine receptor · Cholinesterase · Drug derivative · N(6) cyclopentyladenosine · Organophosphate · Phosphorothioic acid derivative · Bioaccumulation · Cholinergic system · Concentration response · Controlled study · Corpus striatum · Crug efficacy · Enzyme activity · Hippocampus · Intoxication · Male · Microdialysis · Nonhuman · Rat · Reduction · Animal · Drug potentiation · Enzymology · Metabolism · Secretion · Wistar rat · Animals · Cholinesterase Inhibitors · Cholinesterases · Corpus Striatum · Male · Microdialysis · Organothiophosphorus Compounds · Parathion · Phosphoric Acid Esters · Rats · Rats, Wistar · Receptors, Purinergic P1 · Sarin · Acetylcholinesterase, 9000-81-1 · Cyclohexyladenosine, 36396-99-3 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Parathion, 3270-86-8, 56-38-2, 597-88-6 · Sarin, 107-44-8; tabun, 77-81-6 · Acetylcholine, 51-84-3 · Adenosine, 58-61-7; · Cholinesterase Inhibitors · Cholinesterases, EC 3.1.1.8 · N(6)-cyclopentyladenosine, 41552-82-3 · Organothiophosphorus Compounds · Parathion, 56-38- · Phosphoric Acid Esters · Receptors, Purinergic P1 · Sarin, 107-44-8 · Tabun, 77-81-6 · VX, 50782-69-9
[Abstract]

18 A novel safety assessment strategy for non-intentionally added substances (NIAS) in carton food contact materials
article 2014    
Author: Koster, S. · Rennen, M. · Leeman, W. · Houben, G. · Muilwijk, B. · Acker, F. van · Krul, L.
Keywords: Nutrition · Assessment · Complex mixture safety assessment strategy · CoMSAS · Evaluation · Food contact materials · Food matrix · NIAS · Non-intentionally added substances · Safety · Threshold of toxicological concern · TTC · Accident prevention · Electric contacts · Health · Mixtures · Safety engineering · Aflatoxin · Aflatoxin B1 · Aflatoxin B2 · Aflatoxin G1 · Aflatoxin G2 · Aflatoxin M1 · Alcohol derivative · Alkane · Alkene · Biphenyl derivative · Carbamate pesticide · Carboxylic acid · Dibenzodioxin derivative · Dibenzofuran derivative · Ergocornine · Ergocristine · Ergocryptine · Ergometrine · Ergotamine · Ether · Food additive · Fumonisin B1 · HT 2 toxin · Nivalenol · Ochratoxin · Organophosphate pesticide · T 2 toxin · Volatile agent · Vomitoxin · Zearalenone · Article · Concentration (parameters) · Controlled study · Fast food · Food analysis · Food packaging · Food safety · Genotoxicity · Health hazard · Limit of detection · Liquid chromatography · Mass fragmentography · Risk assessment · Food and Nutrition · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

19 Retrospective detection of exposure to nerve agents: Analysis of phosphofluoridates originating from fluoride-induced rectivation of phospylated BuChE
article 2004    
Author: Schans, M.J. van der · Polhuijs, M. · Dijk, C. van · Degenhardt, C.E.A.M. · Pleijsier, K. · Langenberg, J.P. · Benschop, H.P.
Keywords: Biology · Biomarker · Biomonitoring · Butyryl cholinesterase · Fluoride ions · Lexposure · Nerve agents · Organophosphates · Reactivation · Retrospective detection · Cholinesterase · Cholinesterase inhibitor · Cyclosarin · Fluoride · Nerve gas · Organophosphate · Paraoxon · Parathion · Phosphorus derivative · Sarin · Soman · Tabun · Unclassified drug · Biological monitoring · Biological warfare · Chemical structure · Concentration (parameters) · Environmental exposure · Enzyme activation · Enzyme active site · Enzyme inhibition · Gas chromatography · Half life time · Human · Nonhuman · pH · Priority journal · Retrospective study · Rhesus monkey · Animals · Butyrylcholinesterase · Chemical Warfare Agents · Cholinesterase Inhibitors · Cholinesterase Reactivators · Gas chromatography · Female · Fluorides · Half-Life · Humans · Injections, Intravenous · Macaca mulatta · Male · Organophosphorus compounds · Paraoxon · Reference standards · Time factors · Macaca mulatta · Cholinesterase, 9001-08-5 · Cyclosarin, 329-99-7 · Fluoride, 16984-48-8 · Paraoxon, 311-45-5 · Parathion, 3270-86-8, 56-38-2, 597-88-6 · Sarin, 107-44-8 · Soman, 96-64-0 · Tabun, 77-81-6 · Butyrylcholinesterase, EC 3.1.1.- · Chemical warfare agents · Cholinesterase inhibitors · Cholinesterase reactivators · Fluorides · Organophosphorus compounds
[Abstract]

20 A novel safety assessment strategy applied to non-selective extracts
article 2015    
Author: Koster, S. · Leeman, W.R. · Verheij, E.R. · Dutman, A.E. · Stee, L.L.P. van · Munch Nielsen, L. · Ronsmans, S. · Noteborn, H. · Krul, L.
Keywords: Nutrition · Non-selective extract · Safety · Complex mixture safety assessment · Strategy · Threshold of toxicological concern · TTC · Processing · Aflatoxin · Azoxy derivative · Biphenyl derivative · Carbamic acid derivative · Chemical compound · Dibenzodioxin derivative · Dibenzofuran derivative · Miscellaneous drugs and agents · Nitroso derivative · Non selective extract · Organophosphate · Polymer · Protein · Semi volatile substance · Steroid · Sugar · Unclassified drug · Volatile agent · Water · Yoghurt · allergenicity · Analysis · Analytical parameters · Ash · Chemical analysis · Chemistry · Comparative study · Complex mixture safety assessment strategy · Concentration (parameters) · Controlled study · Dietary fiber · Drug mixture · Exposure · Food · Food color · Food composition · Fuit gum · Fruit juice · Genotoxicity · Hazard assessment · Ice cream · Liquid chromatography · Liquid liquid extraction · Mass fragmentography · Mass fragmentography · Nonhuman · Prevention and control · Procedures · Risk assessment · Sambucus · Soft drink · Solid phase extraction · Solid phase microextraction · Squash · Threshold of toxicological concern · Toxicity testing · Chemistry · Complex Mixtures · Food Analysis · Food Contamination · Food Handling · Food Safety · Gas Chromatography-Mass Spectrometry · Hazard Analysis and Critical Control Points · Humans · Methods · Prevention and control · Toxicity · Animalia · Food and Nutrition · Healthy Living · Life Triskelion BV · RAPID - Risk Analysis for Products in Development ARPC - Analytical Research (Pharm & Chemistry) · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 21 found. Next | Sort by date