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1 GLC-analysis and pharmacokinetics of the four stereoisomers of soman
article 1981    
Author: Benschop, H.P. · Berends, F. · Jong, L.P.A. de
Keywords: Biology · Organophosphorus compound · Soman · Animal · Gas chromatography · Kinetics · Metabolism · Rat · Stereoisomerism · Animal · Chromatography, Gas · Kinetics · Organophosphorus Compounds · Rats · Soman · Stereoisomerism · organophosphorus compound · G agents · Prophylaxis · Therapy · Blood · Skin (anatomy) · GC - Gas chromatography · Reaction kinetics · Stereochemistry · Degradation
[Abstract]

2 Elimination kinetics and molecular reaction mechanisms of cyclosarin (GF) by an oxime substituted β-cyclodextrin derivative in vitro
article 2015    
Author: Kranawetvogl, A. · Müller, S. · Kubik, S. · Spruit, W.E.T. · Thiermann, H. · Worek, F. · Noort, D. · Reiter, G.
Keywords: Chemistry · Covalent conjugate · Detoxification · Organophosphorus compound · Supramolecular scavenger · β-cyclodextrin · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

3 The bispyridinium-dioxime HLö-7. A potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman
article 1989    
Author: Jong, L.P.A.de · Verhagen, M.A.A. · Langenberg, J.P. · Hagedorn, I. · Löffler, M.
Keywords: Biology · Bis(pyridinium oxime) derivative · Enzyme inhibitor · Organophosphorus compound · Radioisotope · Enzyme reactivation · Fish · Human · Nonbiological model · Nonhuman · Normal human · Rat · Stereoisomerism · Acetylcholinesterase 9000-81-1 · Animal · Cholinesterase Reactivators · Eels · Human · In Vitro · Organophosphorus Compounds · Oximes · Phosphoric Acid Esters · Pyridines · Pyridinium Compounds · Stereoisomerism · Structure-Activity Relationship · Organophosphorus compounds · Oximes · Phosphoric acid esters · Pyridines · Pyridinium compounds · Soman, 96-64-0 · Tabun, 77-81-6
[Abstract]

4 Retrospective detection of exposure to organophosphorus anti-cholinesterases: Mass spectrometric analysis of phosphylated human butyrylcholinesterase
article 2002    
Author: Fidder, A. · Hulst, A.G. · Noort, D. · Ruiter, R. de · Schans, M.J. van der · Benschop, H.P. · Langenberg, J.P.
Keywords: Warfare · Cholinesterase · Cholinesterase inhibitor · Nerve gas · Organophosphorus compound · Pronase · Sarin · Article · Colorimetry · Enzyme activity · Enzyme assay · High performance liquid chromatography · Hydrolysis · Intoxication · Mass spectrometry · Protein phosphorylation · Spectrometry · Synthesis · Butyrylcholinesterase · Cholinesterase Inhibitors · Environmental Exposure · Environmental Monitoring · Humans · Insecticides · Peptide Fragments · Sarin · Spectrometry, Mass, Electrospray Ionization · Terrorism · Butyrylcholinesterase, EC 3.1.1.- · Cholinesterase Inhibitors · Insecticides · Peptide fragments · Sarin, 107-44-8
[Abstract]

5 Comprehensive gas chromatography with Time of Flight MS and large volume introduction for the detection of fluoride-induced regenerated nerve agent in biological samples
article 2010    
Author: Meer, J.A. van der · Trap, H.C. · Noort, D. · Schans, M.J. van der
Keywords: Defence · Comprehensive GC · Time of Flight MS · Nerve agents · Fluoride reactivation · Diagnosis · Chemicals/CAS: · Fluoride, 16984-48-8 · Sarin, 107-44-8 · Tabun, 77-81-6 · Chemical warfare agents · Cholinesterase inhibitors · Fluorides · Organophosphorus compounds · Phosphoric acid esters · Organophosphate · Organophosphorus compound · Blood · Chemistry · Human · Mass fragmentography · Methodology · Reproducibility · Sensitivity and specificity · Statistical model · Gas Chromatography-Mass Spectrometry · Linear models
[Abstract]

6 Verification of exposure to organophosphates: Generic mass spectrometric method for detection of human butyrylcholinesterase adducts
article 2006    
Author: Noort, D. · Fidder, A. · Schans, M.J. van der · Hulst, A.G.
Keywords: Enzyme inhibition · Ethanol · Mass spectrometry · Phosphates · Plasmas · Proteins · Generic mass spectrometric · Human butyrylcholinesterase adducts · Organophosphates · Phosphylated peptides · Biochemistry · Cholinesterase · Cholinesterase inhibitor · Dichlorvos · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Nerve gas · Nonapeptide · Organophosphate pesticide · Organophosphorus compound · Pepsin A · Phosphoserine · Procainamide · Proton · Sarin · Soman · Analytic method · Article · Biological monitoring · Chemical warfare · Cholinesterase inhibition · Human · Liquid chromatography · Plasma · Solid phase extraction · Spectrometer · Tandem mass spectrometry · Terrorism · Time of flight mass spectrometry · Butyrylcholinesterase · Chromatography, Liquid · Humans · Phosphoric Acid Esters · Solid Phase Extraction · Tandem Mass Spectrometry
[Abstract]

7 Characterization of human cytochrome P450s involved in the bioactivation of tri-Ortho-Cresyl phosphate (ToCP)
article 2015    
Author: Reinen, J. · Nematollahi, L. · Fidder, A. · Vermeulen, N.P.E. · Noort, D. · Commandeur, J.N.M.
Keywords: Toxicology · Cytochrome P450 1A2 · Cytochrome P450 2C18 · Cytochrome P450 2D6 · Cytochrome P450 3A4 · Cytochrome P450 3A5 · Organophosphorus compound · Unclassified drug · Animal cell · Biotransformation · Cholinesterase inhibition · Controlled study · Enzyme inactivation · Humans · human cell · Hydrolysis · IC50 · In vitro study · Liver microsome · Liver microsome metabolism · Neurotoxicity · Nonhuman · Rats · Acetylcholinesterase, 9000-81-1 · Cholinesterase, 9001-08-5 · cytochrome P450, 9035-51-2 · Cytochrome P450 3A4, 329736-03-0 · Cytochrome P450 3A5, 336874-97-6 · Tri ortho cresyl phosphate, 78-30-8 · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

8 Improvements of the fluoride reactivation method for the verification of nerve agent exposure
article 2004    
Author: Degenhardt, C.E.A.M. · Pleijsier, K. · Schans, M.J. van der · Langenberg, J.P. · Preston, K.E. · Solano, M.I. · Maggio, V.L. · Barr, J.R.
Keywords: Warfare · Biological marker · Cholinesterase · Cyclosarin · Organophosphorus compound · Potassium fluoride · Sarin · Soman · Tabun · Unclassified drug · Calibration · Chemical analysis · Chemical warfare · Enzyme activity · Gas chromatography · Human · Mass spectrometry · Methodology · Neurotoxicity · Plasma · Solid phase extraction · Biological Markers · Butyrylcholinesterase · Chemical warfare agents · Cholinesterase reactivators · Environmental exposure · Environmental monitoring · Erythrocytes · Fluorides · Gas Chromatography-Mass Spectrometry · Humans · Reproducibility of results · Sensitivity and specificity · Cholinesterase, 9001-08-5 · Cyclosarin, 329-99-7 · Potassium fluoride, 7789-23-3 · Sarin, 107-44-8 · Soman, 96-64-0 · Tabun, 77-81-6 · Biological Markers · Butyrylcholinesterase, EC 3.1.1.- · Chemical Warfare Agents · Cholinesterase reactivators · Fluorides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date